CARBOHYDRATE POLYMERS
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2024
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IF 10.7
Tanjun Deng,Wenli Lu,Xiaoxian Zhao,Haoyu Wang,Yumeng Zheng,Ao Zheng,Zhengyu Shen
Chronic wounds with bacterial infection present formidable clinical challenges. In this study, a versatile hydrogel dressing with antibacterial and angiogenic activity composite of silk fibroin (SF), chondroitin sulfate (CS), and graphene oxide quantum dots (GOQDs) is fabricated. GOQDs@SF/CS (GSC) hydrogel is rapidly formed through the enzyme catalytic action of horseradish peroxidase. With the incorporation of GOQDs both gelation speed and mechanical properties have been enhanced, and the photothermal characteristics of GOQDs in GSC hydrogel enabling bacterial killing through photothermal treatment (PTT) at ~51 °C. In vitro studies show that the GSC hydrogels demonstrate excellent antibacterial performance and induces type H vessel differentiation of endothelial cells via the activated ERK1/2 signaling pathway and upregulated SLIT3 expression. While in vivo results show that the hydrogel significantly promotes type H vessels formation, which related to the collagen deposition, epithelialization and, ultimately accelerating the regeneration of infected skin defects. Collectively, this multifunctional GSC hydrogel, with dual action of antibacterial efficacy and angiogenesis promotion, emerges as an innovative skin dressing with potential for advancing in infected wound healing.
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PubMed
高影响因子
MICROCHEMICAL JOURNAL
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2024
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IF 4.9
Xiaohong Tan,Wenzhan Li,Wei He,Tingting Yu,Bingbing Wan,Yong Huang,Jintao Liang,Guiyin Li
Glypican-3 (GPC3), which is a surface heparan sulfate proteoglycan, has been widely known the ideal biomarker for diagnosis and treatment of hepatocellular carcinoma (HCC). Accurate and sensitive detection of serum GPC3 level is an important and challenging task. In this paper, a sandwich electrochemical aptasensor was designed to specifically detect serum GPC3 level through aptamer-target-aptamer recognition. A GPC3 aptamer (GPC3 Apt ) immobilized on the surface of gold nanoparticles@reduced graphene oxide modified screen-printed electrode (Au NPs@rGO/SPCE) was used as the capture probe. Hemin-reduced graphene oxide-carboxymethyl chitosan@platinum nanoparticles (H-rGO-CMC@Pt NPs), with good mimicking peroxidases activity, were labeled with amination GPC3 aptamer, which was employed as the signal probe. Once the target GPC3 was anchored on the surface of GPC3 Apt /Au NPs@rGO/SPCE, the H-rGO-CMC@Pt NPs-GPC3 Apt was further specifically bound to the GPC3, forming the aptamer-target-aptamer sandwich structure, which can catalyze the oxidation of hydroquinone (HQ) to benzoquinone (BQ) and lead the oxidation current of HQ recorded by DPV to changing. The linear relationship between the current signal of oxidation of HQ and GPC3 concentration range of 0.0001–3.0 µg/mL and 3.0–60.0 µg/mL, with a low detection limit (LOD) of 0.0685 ng/mL. Additionally, the electrochemical aptasensor was successfully applied for the detection of GPC3 in human serum samples with the recovery of 99.95–104.06 % and relative standard deviation (RSD) of 1.31–5.22 %. Thus, the sandwich aptasensor could provide a new strategy for detection of serum GPC3 level and improve the early diagnosis rate of HCC.
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高影响因子
NEW JOURNAL OF CHEMISTRY
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2025
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IF 2.5
Xiao-Jian Li,Xinli Lu,Yunxia Wang,Zhanquan Zhang,Yongfa Zhang
This study successfully developed a highly sensitive electrochemiluminescence (ECL) sensor based on the ECL resonance energy transfer mechanism for detecting the key biomarker of acute myocardial infarction, heart–type fatty acid binding protein (h–FABP). Through the meticulous design of the Ag/Cu2O/Ti3C2 ternary nanocomposite material, this material demonstrated significant catalase–like catalytic activity, enabling the efficient decomposition of H2O2 to generate more superoxide radicals (O₂•⁻), thereby significantly enhancing the ECL signal of the luminol–H2O2 system. Notably, AgS quantum dots (AgS QDs), due to broad–spectrum ultraviolet absorption overlapping with the ECL emission spectrum of luminol, triggered an efficient energy resonance transfer effect, resulting in the decrease of ECL intensity. NH2–MIL–101(Fe) was utilized to couple with AgS QDs (AgS QDs@NH2–MIL–101(Fe)), which can further enhance the quenching efficiency. Based on this signal–off strategy, an ultrasensitive detection platform for h–FABP was successfully constructed. Experimental results indicated that the immunosensor exhibited an excellent response relationship within a wide linear range from 1.00 fg mL–1 to 100 ng mL–1, and a low detection limit reached 0.36 fg mL–1 (S/N = 3). This study provides an innovative methodological approach for ultra–trace detection of myocardial injury markers and demonstrates significant application potential in early clinical diagnosis.
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高影响因子
Molecular Catalysis
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2024
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IF 3.9
XiaoNing Gao,YanXiao Zhang,Wei Fu,Hong Zhou,Lu Feng
Conventional hydrolysis of total saponins for the extraction of diosgenin, an essential ingredient in the production of steroid hormones, has caused significant ecological pollution, making efficient and clean extraction methods necessary. Here, UiO-66-NH 2 with defect sites containing Zr-coordinated hydroxide and water groups was synthesized using concentrated HCl as a crystal modulator, which was further treated with trimethylsilyl trifluoromethanesulfonate (Me 3 SiOTf) to afford UiO-66-NH 2 OTf using the oxygen affinity of the Me 3 Si group. The strong Lewis acid UiO-66-NH 2 OTf was used to extract diosgenin from the total saponin, and the extraction temperature, extraction time and amount of addition were optimized using single-factor experiments and the response surface method. In addition, high-resolution mass spectrometry has been used to analyze the resulting compounds, thus suggesting an alcoholysis pathway and an alcoholysis mechanism for the total saponins.
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高影响因子
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
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2024
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IF 4.9
Hongxin Yan,Guoqing Xiao,Chunlin Chen,Mingtan Wang,Rui Zou,Yinke Lan,Jing Gou,Junjie Cao,Xiyi Ma
Hexagonal boron nitride (h-BN) has excellent lamellar structure and electrical insulation properties, and excels in improving the corrosion resistance of coatings. By utilizing the abundant hydroxyl and amino functional groups on the polydopamine surface, h-BN is endowed with excellent hydrophilicity. Simultaneously, the polysaccharide polymer MD-GT-CS (MGC), formed by cross-linking maltodextrin (MD), gelatin (GT), and chitosan (CS), was combined with the active sites on the surface of BN@PDA, which conferred pH-responsive functionality to the BN@PDA@MGC hybrid material. In addition, cerium ions were introduced into the carboxyl and amino sites on the MGC surface, resulting in the synthesis of BN@PDA@MGC(Ce) (BPMGC), a hybrid material that combines the layered barrier properties, pH responsiveness, and self-repairing functions. The BPMGC/EP composite coating was prepared by doping the hybrid material with EP. The EIS test results showed that the |Z| 0.01 Hz value of the composite coating reached 1.45 × 10 9 Ω cm 2 after 40 d, which is an improvement of four orders of magnitude compared to EP (6.85 × 10 5 Ω cm 2 ). The results of EIS tests at different pH conditions showed that after 40 d of immersion at pH = 3 and 5, the |Z| 0.01 Hz value decreased by two orders of magnitude, but was still two orders of magnitude higher than that of EP at pH = 7. Meanwhile, the strong self-healing ability of BPMGC/EP was determined by EIS analysis of the scratched coating, salt spray test, SEM and EDS analysis of the corroded area. The experimental results show that the incorporation of BPMGC provides a new method to improve the barrier and self-healing properties of epoxy resins.
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高影响因子
Advanced Membranes
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2025
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IF 9.5
Yixin Wang,Yingda Huang,Kang Geng,Bin Hu,Ruofei Gao,Erqiang Yang,Junfen Li,Jiandang Xue,Nanwen Li
Anion exchange membrane (AEM) is a core component of potentially more efficient and cost-effective anion exchange membrane water electrolyzers (AEMWEs), which combine the advantages of traditional alkaline water electrolyzers (AWEs) and proton exchange membrane water electrolyzers (PEMWEs). Despite extensive research efforts in recent years, AEMs still face significant challenges, particularly insufficient alkaline stability and limited dimensional/mechanical stability. In this work, we enhanced the mechanical and alkaline stability of AEMs by incorporating the thermoplastic elastomer polystyrene-block-polybutadiene-block-polystyrene (SBS) into the poly (terphenyl piperidinium) (PTP) matrix. The optimal PTP-SBS-2.5% membrane exhibits outstanding dimensional stability (9.4% swelling at 20 °C), robust mechanical properties (tensile strength of 51.5 MPa and elongation of 63.1% at break in wet state), low alkali absorption (0.875%) and exceptional alkaline stability (92.4% conductivity retention after 1500 h). Notably, the membrane demonstrates stable operation in AEMWE for over 3000 h with a low voltage decay rate of 41.1 μV h –1 . These results highlight the significance of SBS in enhancing both the alkaline stability and mechanical performance of PTP-based AEMs.
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高影响因子
ADVANCED FUNCTIONAL MATERIALS
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2025
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IF 19
Yu Bai,Haiping Zhou,Jia-Lin Yang,Qingqing Pan,Jiawei Wang,Yunpeng Wu,Xing-Long Wu
Aqueous zinc-ion batteries (AZIBs) have great potential for large-scale energy storage applications. However, the parasitic reactions, such as continuous hydrogen evolution reaction (HER), seriously hamper the reversibility and cycling stability of the zinc metal anode (ZMA), limiting its practical application. In this paper, a pre-growth interfacial layer strategy is adopted to grow the enol/ketone conversion interfacial layer on the surface of ZMA (denoted as Zn@AA). H + can be reversible “lock/unlock” during reversible enol/ketone conversion reaction. It not only broadens the capacity of AZIBs (Zn 2+ /H + co-insertion), but also inhibits the HER reaction (the amounts of H 2 evolution decreased obviously in both Zn@AA||Zn@AA and Zn@AA||VO 2 ·H 2 O@Ppy (Ppy denote as polypyrrole) cells by on-line differential electrochemical mass spectrometry analysis), thereby improving its stability performance. The cycle life of the assembled Zn@AA||Zn@AA cell exceeded 3200 h at 1 mA cm −2 and 1 mA h cm −2 . Furtherly, the Zn@AA||VO 2 ·H 2 O@Ppy full cell also exhibited excellent cycling stability and capacity retention. This work provides new ideas for modifying the ZMA interfacial layer to inhibit the HER, which guides the development of AZIBs.
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高影响因子
CHEMICAL ENGINEERING JOURNAL
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2025
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IF 13.2
Mengting Liu,Fu Yang,Hongyao Zhao,Xiu Zhong,Ruiting Ni,Kwame Nana Opoku,Zhenxiao Wang,Yangping Zhang,Yanyun Wang,Feng Zeng,Yinlong Zhu,Weidong Shi
In electrochemical nitrate reduction reaction (NITRR), the generation of active hydrogen (*H) and its poor utilization in conversion of various nitrate intermediates often cause mismatched kinetics, resulting in low ammonia yield rate (YR NH3 ) and Faraday efficiency (FE NH3 ). Herein, we construct a spatially-confined Cu/Fe 2 O 3 heterointerfaces within porous carbon fiber, featuring oxygen vacancy-rich iron oxide nanoparticles (∼14.7 nm) interface-coupled well-dispersed Cu nanocrystals. The interfacial metallic copper sites with optimized interfacial electron transfer accelerate the consumption of NO 2 – through supplying the most abundant active *H to equilibrate NITRR kinetics. The easy desorption of generated NH 3 from active sites facilitates the accelerated reaction cycles by rapidly exposing the spent active sites. Correspondingly, this catalyst achieves nearly 100 % nitrate conversion, with a YR NH3 of 81.3 mg h −1 mg cat -1 , FE NH3 of 98.11 %, and 100 % NH 3 selectivity without any nitrite accumulation, outperforming most state-to-art catalysts as reported. Impressively, when nitrite acts as reactant, ammonia synthesis through nitrite reduction reaches YR NH3 of 99 mg h −1 mg cat -1 and FE NH3 of 99.44 % outperforming all the same series reported. Moreover, active *H quenching and isotope labeling experiments uncover the generation of the most abundant active *H species and their high utilization among the reported results. Density function theory (DFT) calculations further indicate the interfacial Cu/Fe 2 O 3 regulates the d-band center of the catalyst, optimizing the adsorption of nitrate and further lowering the reaction energy barrier of the decisive step (*NO→*NOH).
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高影响因子
CHEMICAL ENGINEERING JOURNAL
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2022
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IF 16.744
Weijie Zhang,Shunshun Zhao,Yupeng Xing,Hongjie Qin,Qiling Zheng,Penghui Zhang,Shouwei Zhang,Xijin Xu
The sustainable conversion from solar energy to chemical energy is realized by using photocatalytic technology to produce hydrogen and hydrogen peroxide. In this work, the construction of a direct Z-scheme heterojunction is of great significance for improving the efficiency and stability of photocatalytic hydrogen evolution (PHE) and photocatalytic hydrogen peroxide production (PHP). In this study, P-doped h-BN (PBN) nanosheets are used to support the in-situ growth of ZnIn 2 S 4 nanoflowers via wet chemical method, and sandwich-like PBN/ZnIn 2 S 4 hierarchical heterostructures are successfully synthesized. The PHE performance of PBN/ZnIn 2 S 4 (∼59.46 μmol/h) is ∼ 2.35 times than that of the original ZnIn 2 S 4 (∼25.27 μmol/h), and the PHP performance (∼122.82 μmol/L/h) is 39.37 times than that of PBN (∼3.12 μmol/L/h). The excellent photocatalytic performance of PBN/ZnIn 2 S 4 can be attributed to the following points: (1) the acceleration of the separation of photogenerated electron-hole pairs induced by the formation of Z-scheme heterostructure; (2) reasonable design and construction of sandwich-like PBN/ZnIn 2 S 4 hierarchical heterostructure; (3) the promotion the migration and separation of photogenerated carriers by the built-in electric field. This work provides new ideas for the development of high-efficiency PHE and PHP Z-scheme heterojunction photocatalyst design.
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高影响因子
JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY
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2025
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IF 14.3
Fan Fan,Hao Xiu,Huiting Ma,Yuting Wang,Yongpeng Cui,Wenqing Yao,Yajun Wang
Efficient separation and rapid migration of photogenerated charges are crucial for achieving high photocatalytic H₂O₂ production. In this study, a K, P, and O co-doped carbon nitride (KPOCN- x ) was synthesized through simple one-pot polymerization for efficient photocatalytic H₂O₂ production. The synergistic doping of metal and non-metal elements enhances light absorption and simultaneously promotes both in-plane and interplane photogenerated charge transfer. Induced by multi-heteroatom doping, especially the form of K bridging, the built-in electric field of KPOCN-5 increases up to 2.27 times that of undoped polymeric carbon nitride (Bulk CN), facilitating the efficient separation of photogenerated charges. Meanwhile, the rod-shaped structure shortens the migration distances of photogenerated charges, further promoting electron transfer and minimizing recombination. As a result, the H₂O₂ production rate of KPOCN-5 reached 3306.6 μmol g −1 h −1 under visible light, approximately 50 times higher than that of Bulk CN. This work highlights the construction of a giant built-in electric field as a powerful strategy for boosting the photocatalytic production of H₂O₂.
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高影响因子
ENVIRONMENTAL SCIENCE & TECHNOLOGY
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2019
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IF 7.149
Huiling Liu,Jinglong Han,Jili Yuan,Chengbin Liu,Dong Wang,Tian Liu,Meijun Liu,Jinming Luo,Aijie Wang,John C. Crittenden
Efficient elimination of antibacterial activity of halogenated antibiotics by dehalogenation pretreatment is desired for a biochemical treatment process. In this study, crystalline cobalt phosphide nanosheet arrays on a Ti plate (C-CoP/Ti) are fabricated by a simple electrodeposition and phosphorization process. The crystalline structure greatly promotes atomic hydrogen (H*) generation. Moreover, the nanosheet arrays can provide abundant active sites and accelerate electron transfer and mass transport. As a result, the dehalogenation rate of florfenicol (FLO, an emerging organic pollutant) on C-CoP/Ti is 11.1, 2.97, and 13.6 times higher than that on amorphous CoP/Ti, Pd/Ti, and bare Ti, respectively. The C-CoP/Ti electrode achieves 97.4% dehalogenation of FLO (20 mg L–1) within 30 min at −1.2 V (vs Ag/AgCl). Nearly 100% of Cl and 20% of F are broken away within 120 min, showing the highest electrocatalytic defluorination efficiency reported so far. Both experimental results and theoretical calculations reveal that the dehalogenation of FLO on C-CoP/Ti is synergistically accomplished via direct reduction of electron transfer and indirect reduction of H*. This study develops a highly efficient non-noble metal electrode material for dehalogenation of halogenated organic compounds.
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PubMed
高影响因子
JOURNAL OF ORGANIC CHEMISTRY
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2019
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IF 4.745
Na Li,Jinku Bai,Xiaolin Zheng,Honghua Rao
An iron-catalyzed methylene forming strategy is disclosed through sequential C–H and C–O bond functionalization of methanol with cosolvent water. This protocol provides an easy and novel access to methylene-tethered imidazo[1,2-a]pyridine and 2-aminopyridine analogues in a sustainable manner and represents a complementary approach to traditional methylene forming strategies.
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PubMed
高影响因子
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