COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
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2023
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IF 5.2
Aijing Li,Xinpeng Chen,Yurong Sun,Jin Cheng,Ping Yao,Tieling Xing,Guoqiang Chen
An essential factor affecting the photocatalytic efficiency of a catalyst is the efficient separation of photogenerated electrons and holes. In the present study, a novel heterojunction material, PCN@GO/AgNPs, was synthesized with the aim of improving the photocatalytic performance. This achievement was accomplished through the establishment of a heterojunction between graphitic phase carbon nitride (PCN) and nano silver (AgNO 3 ). The PCN was prepared from melamine powder calcined at high temperature under nitrogen environment, and was modified by graphene oxide (GO) to form heterojunction with silver nanoparticles, which resulted in a significant improvement in the photocatalytic efficiency of the catalyst. Under ultraviolet（UV）excitation, the catalytic rate constant of PCN@GO/AgNPs heterojunction on RhB dye can reach 10.594 × 10 −2 min −1 . This research represents a promising strategy to increase the surface area of PCN photocatalysts through simply doping noble metal and thus improving photocatalytic performance, which contributes to understand the reaction mechanism of photocatalytic effect.
研究领域:
材料科学
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环境科学
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化学
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产品关联
DOI
高影响因子
JOURNAL OF CHROMATOGRAPHY A
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2024
·
IF 3.8
Zirou Wang,Sitian Gu,Yu Ma,Huixiao Duo,Wei Wu,Qingli Yang,Xiudan Hou
An efficient PCN-224/graphene aerogel modified silica (PCN-224/GA@Sil)-based extraction method was established for monitoring the degradation process of two organophosphorus pesticides (OPPs) in juice. PCN-224/GA@Sil exhibited higher surface area (307.35 m 2 g -1 ) than graphene oxide modified silica (254.09 m 2 g -1 ). The introduction of PCN-224 endowed the sorbent with excellent adsorption specificity towards OPPs due to the ZrˑˑˑS/O coordination bond. PCN-224 exhibited relatively higher theoretical adsorption energies of PCN-224 towards fenitrothion and fenthion were 0.68 eV and -0.31 eV. The established PCN-224/GA@Sil-HPLC method showed the linearity of 0.2–500 μg L -1 for analytes. The matrix effects in juice were 9.68 % and 3.61 % for fenitrothion and fenthion. Finally, it was used for the sample pretreatment of juice preventing interference from food matrices to monitor the degradation of two OPPs. A combination method of ultrasound and xenon lamp was adopted to degrade fenitrothion and fenthion displaying the synergistic effect ( SE =2.12, 1.39).
研究领域:
分析化学
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环境科学
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食品科学
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材料科学
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产品关联
DOI
PubMed
高影响因子
PEST MANAGEMENT SCIENCE
·
2025
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IF 3.8
Haoxiang Zhu,Ying He,Yaqi Liu,Jianhua Guo,Jingxuan Zhu,Yunzhe Li,Kun Qian
BACKGROUND Pyrethroids are widely used insecticides due to their efficacy and safety for humans, yet their toxicity to beneficial insects like bees remains a critical environmental concern. Developing controlled-release formulations to mitigate non-target toxicity and enhance pesticide efficiency is imperative for sustainable agriculture. RESULTS In this experiment, two types of PCN-222 materials, with small and large particle sizes, were synthesized using a solvothermal method. Bifenthrin (Bif) was loaded onto PCN-222 to prepare the controlled-release agent Bif@PCN-222. The structure and properties of the prepared materials were characterized by morphology observation, infrared spectroscopy, thermogravimetric analysis, and contact angle measurements. The experimental findings indicated that Bif@PCN-222 demonstrated excellent release performance under alkaline conditions and exhibited better wettability on cabbage leaves compared to commercial formulations. Additionally, the Bif@PCN-222 controlled-release agent significantly improved resistance to UV photodegradation. Safety evaluations showed that Bif@PCN-222 had minimal impact on the growth of Zoysia grass and notably reduced toxicity to bees. CONCLUSION These results show that we have successfully prepared Bif@PCN-222, which can enhance the pest control effect, reduce the toxicity to non - target organisms, and have a relatively small impact on plant growth and the number of soil microflora. © 2025 Society of Chemical Industry.
研究领域:
环境科学
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农业化学
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纳米技术
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农药制剂
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生态毒理学
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产品关联
DOI
PubMed
高影响因子
MICROCHEMICAL JOURNAL
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2025
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IF 5.1
Xiudan Hou,Zirou Wang,Hui Yu,Yufei Liu,Qingli Yang
Excess residues of organophosphorus pesticides in traditional Chinese medicinal herbs has been driving the development of rapid and specific detection methods. Herein, a dual-mode sensing platform was established for the simultaneous determination of glyphosate and profenofos using the colorimetric and fluorescence sensors, respectively. A Zn-incorporated porous coordination network-224 (PCN-224) was prepared to selectively adsorb glyphosate based on the coordination effect of Zr and phosphate ion, which would inhibit the peroxidase-like activity of PCN-224(Zn). An aptamer-modified nitrogen-carbon quantum dots (N-CQDs) was used to specifically recognize profenofos, further adopting the quenching effect of PCN-224(Zn) towards N-CQDs to realize the quantitative analysis. The colorimetric sensing mechanism was also studied. Coupled with a smartphone application, the established method exhibited the linearity of 0.06–3.1 μg mL −1 (glyphosate), and 0.02–3.9 μg mL −1 (profenofos). The matrix effect was 100.58 % and 95.46 % in Angelica sinensis and Codonopsis , presenting a new horizon for the multi-model sensor in real samples.
研究领域:
分析化学
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环境科学
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药学
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产品关联
DOI
高影响因子
JOURNAL OF CATALYSIS
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2022
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IF 8.047
Hong Li,Yiming Wang,Rongxiu Guo,Jianwei Zheng,Zejun Sun,Xinyue Zhang,Ying Guo,Hongna Jia,Qionglin Liang,Hong-bin Sun
The heterogeneously tandem catalytic synthesis is a step-economic and work-up-saving strategy for producing chemicals, but it usually requires a special catalyst to achieve the sequential catalytic reactions . The development of metal organic frameworks provides an opportunity to fabricate multifunctional catalysts. In this work, a MOF-based sandwich-nanostructure catalyst UiO-66-NH 2 @Pt@PCN-222 is fabricated, which is made of the UiO-66-NH 2 as the core, Pt nanoparticles as the interlayer, and the defective PCN-222 as the shell. The developed catalyst shows outstanding performance for the tandem catalytic synthesis, which is the hydrogenation of nitroarenes cascaded with β-dicarbonyl compounds to form β-ketoenamines. The selectivity of β-ketoenamines reached 98% upon the completed hydrogenation of p-nitrotoluene. The stable PCN-222 shell can be regarded as an active armor, which not only protects the Pt particles from leaching or agglomerating, but also has plenty of acid sites that are conducive to the second-step condensation. At the same time, the kinetic studies show that the armor layer also affects the activity of hydrogenation, so that the hydrogenation and condensation reactions can proceed simultaneously to give the best selectivity. Various substituted dicarbonyl compounds and structurally different nitroarenes completed the conversion with excellent conversion (90–99%) and selectivity (87–98%), and this nanocatalyst can be recycled for up to six cycles without the expense of activity.
研究领域:
材料科学
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催化化学
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产品关联
DOI
高影响因子
ACS Applied Nano Materials
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2023
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IF 5.9
Longbao Zhu,Ting Gui,Ping Song,Wanzhen Li,Jun Wang,Chengrui Hu,Yuanchen Sun,Fei Ge,Weiwei Zhang
Chemodynamic therapy (CDT) is a highly promising tumor treatment modality that uses the Fenton reaction to convert intracellular hydrogen peroxide (H2O2) into cytotoxic hydroxyl groups (•OH). However, the therapeutic effects of CDT have been restricted by weak acidic pH values, insufficient H2O2 levels, and high glutathione (GSH) concentrations in the tumor microenvironment (TME). In this study, to construct PCN-224-Pt/GOD, porphyrin-based metal–organic framework nanoparticles (PCN-224) were used as the carrier to load Pt and glucose oxidase (GOD). The surface of PCN-224-Pt/GOD was covered with manganese dioxide (MnO2) to fabricate the multifunctional composite nanoparticles PCN-224-Pt/GOD@MnO2 (P–P/GOD@Mn). P–P/GOD@Mn was used to increase H2O2 levels and to decrease GSH levels for combined CDT and starvation therapy. As a result, we developed P–P/GOD@Mn nanoparticles (diameter, approximately 280 nm) with favorable size and biocompatibility. Under simulated TME conditions, P–P/GOD@Mn nanoparticles could catalyze H2O2 to generate cytotoxic hydroxyl radicals (•OH), consume glutathione (GSH), and decompose H2O2 to generate oxygen (O2). Cellular toxicity assay results showed that P–P/GOD@Mn killed MCF-7 cells in the TME, with a rate of 77%. The results of tumor-bearing mouse experiments proved that P–P/GOD@Mn nanoparticles could significantly suppress tumor cell growth, which shows the great potential of this entity in CDT and its possibility in bimodal cancer therapy.
研究领域:
生物医学工程
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肿瘤治疗
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纳米医学
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产品关联
DOI
高影响因子
ACS Applied Materials & Interfaces
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2021
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IF 9.229
Yuheng Bao,Jifan Chen,Huiqiang Qiu,Cong Zhang,Pintong Huang,Zhengwei Mao,Weijun Tong
Sonodynamic therapy (SDT) is a promising method for tumor treatment, but self-quenching property, low loading efficiency of sonosensitizers, and hypoxia tumor microenvironment (TME) hinder the efficiency of SDT. Herein, an erythrocyte membrane (EM)-camouflaged metal–organic framework (MOF) of PCN-224 nanoparticles (NPs) integrated with platinum (Pt) NPs as well as glucose oxidase (GOx) has been developed to overcome these limits. Porphyrin-based PCN-224 NPs are synthesized as a sonosensitizer with a large amount of well-organized porphyrin molecules while simultaneously acting as the nanocarriers (NCs) for Pt NPs and GOx. When the NCs are internalized by tumor cells, Pt NPs on their surface are able to utilize endogenous hydrogen peroxide (H2O2) to produce oxygen for the relief of tumor hypoxia, thus enhancing the SDT effect. After EM cloaking, the longer circulation time can improve biocompatibility in vivo and enhance accumulation in tumor tissue. Loaded GOx is beneficial to local glucose consumption and can realize the tumor starvation therapy effect. Consequently, these multifunctional NCs show amplified synergistic therapeutic effects of tumor SDT and starvation therapy, which can efficiently inhibit the tumor growth.
研究领域:
生物医学工程
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肿瘤治疗学
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纳米医学
✓ 已验证
DOI
PubMed
高影响因子
Small Structures
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2025
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IF 11.3
Jiaojiao Fan,Jianmin Chen,Wenji Li,Zhongxing Zhao,Zhenxia Zhao
Converting CO 2 into high-value-added products via “artificial photosynthesis” under mild conditions is a promising yet challenging strategy for developing efficient photocatalysts. This study reports a simple two-step solvothermal approach to fabricate the dual-metal–organic framework (MOF) nanocomposite NH 2 -UiO-66@PCN-224 (NU-66@PCN-224) with tightly integrated interfaces, which achieves efficient CO 2 to CO photocatalytic reduction under light irradiation. The epitaxially grown PCN-224, composed of Zr 6 clusters and tetrakis (4-carboxyphenyl) porphyrin (TCPP), serves as a shell layer and a visible light-absorbing antenna, thereby broadening the light absorption range of the composite material. Moreover, the tightly integrated interfaces of NU-66@PCN-224 enhance the mobility of photogenerated charge carriers, consequently enhancing its capability for CO 2 catalytic reduction. As a result, the combination of NU-66 and PCN-224 retains their individual advantages while achieving a synergistic enhancement of both adsorption and catalysis, further improving the photocatalytic performance. The as-prepared NU-66@PCN-224 catalyst exhibits outstanding photocatalytic performance, yielding 74.6 μmol g −1 h −1 of CO under irradiation without sacrificial agents or photosensitizers. This work demonstrates a straightforward and effective method for designing MOF-on-MOF photocatalysts with enhanced photoactivity.
研究领域:
材料科学
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纳米技术
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环境科学
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光催化
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能量转换
✓ 已验证
产品关联
DOI
高影响因子
FOOD CHEMISTRY
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2024
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IF 8.5
Bolong Fang,Xin Liu,Juan Peng,Yuzhi Li,Zhiyong Gong,Weihua Lai
In this study, a type of luminescent porous coordination network-224 (PCN-224) in alkaline conditions was synthesized with the dramatic fluorescence enhancement by 20.4 times, which was explained by the fact that the decrease of Zr 4+ content in alkaline conditions resulted in the partial recovery of the electron cloud density of 4,4′,4′′,4′′′-(Porphine-5,10,15,20-tetrayl) tetrakis(benzoic acid) (TCPP). Given the large overlap between the excitation spectrum of PCN-224 and the absorption band of Ag nanoparticles (Ag NPs), the coating of the Ag layer on PCN-224 triggered the fluorescence quenching effect, which was applied to “turn off” fluorescence immunoassay for sensitive detection of Escherichia coli O157:H7 ( E. coli O157:H7) in milk. The proposed immunoassay reached a low limit of detection (LOD) of 3.3 × 10 2 CFU mL −1 , 29.7 times more sensitive than the conventional ELISA. It will provide a novel alternative strategy for sensitively detecting pathogenic bacteria in the field of food safety.
研究领域:
材料科学
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分析化学
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食品安全
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生物传感器
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产品关联
DOI
PubMed
高影响因子
ACS Applied Nano Materials
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2024
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IF 5.3
Xinxing Sun,Qiuyue Wang,Hongyang Bao,Yitong Liu,Sicheng Yao,Mingming Li,Naiying Chen,Yang Chen
Sonodynamic therapy (SDT) is a novel therapeutic modality that is effective for the noninvasive treatment of dermatological diseases. As a ubiquitous large class of sonosensitizers, however, porphyrins suffer from poor skin permeability and the inefficient generation of reactive oxygen species. Herein, different-sized porphyrinic metal–organic frameworks (MOFs), PCN-224 (90, 125, and 200 nm), were developed via the coordination of tetra-kis(4-carboxyphenyl) porphyrin (TCPP) and the metal zirconium to enhance the local delivery of porphyrins, and fluorescent sonosensitizers (methylene blue or rhodamine 6G) were further incorporated to improve the sonodynamic effect, as well as to visualize the delivery of PCN-224 and its cargo. The skin penetration of PCN-224 was found to be increased with the reduction of particle size, and all three-sized samples could overcome the barrier of stratum corneum, even achieving the dermis of the porcine skin. Both intercellular and follicular pathways were noticed for three-sized PCN-224, while the follicular one played a more significant role in the penetration of the smallest PCN-224. The intact nanoparticles were found in the skin. At the initial stage, the nanoparticle and its cargo penetrated the skin as an intact entity, while the encapsulated rhodamine 6G was slowly released to the microenvironment of the skin from the nanoparticle with the prolongation of application. The combination of PCN-224 and methylene blue could increase the acoustically triggered generation of 1O2, distinctly boosting the lethal effect against the cancerous cell. Collectively, the study revealed the feasibility of PCN-224 for topical use, suggested an innovative method to enhance the sonodynamic effect, and proposed a possible mechanism for skin drug delivery of MOFs.
研究领域:
药学
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材料科学
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皮肤病学
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纳米技术
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治疗学
✓ 已验证
产品关联
DOI
高影响因子
Nano Research
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2020
·Vol. 13
·期 1
·273-281
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IF 8.183
Zhang Tao,Jiang Zhenqi,Chen Libin,Pan Chunshu,Sun Shan,Liu Chuang,Li Zihou,Ren Wenzhi,Wu Aiguo,Huang Pintong
As nanomedicine-based clinical strategies have continued to develop, the possibility of combining chemotherapy and singlet oxygen-dependent photodynamic therapy (PDT) to treat pancreatic cancer (PaC) has emerged as a viable therapeutic modality. The efficacy of such an approach, however, is likely to be constrained by the mechanisms of drug release and tumor oxygen levels. In the present study, we developed an Fe(III)-complexed porous coordination network (PCN) which we then used to encapsulate PTX (PCN-Fe(III)-PTX) nanoparticles (NPs) in order to treat PaC via a combination of chemotherapy and PDT. The resultant NPs were able to release drug in response to both laser irradiation and pH changes to promote drug accumulation within tumors. Furthermore, through a Fe(III)-based Fenton-like reaction these NPs were able to convert H 2 O 2 in the tumor site to O 2 , thereby regulating local hypoxic conditions and enhancing the efficacy of PDT approaches. Also these NPs were suitable for use as a T 1 -MRI weighted contrast agent, making them viable for monitoring therapeutic efficacy upon treatment. Our results in both cell line and animal models of PaC suggest that these NPs represent an ideal agent for mediating effective MRI-guided chemotherapy-PDT, giving them great promise for the clinical treatment of PaC.
研究领域:
肿瘤学
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放射学
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纳米医学
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治疗诊断学
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产品关联
DOI
高影响因子
ACS Applied Nano Materials
·
2020
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IF 0
Enqing Liu,Jiangping Zhu,Weijun Yang,Fan Liu,Can Huang,Shuangfeng Yin
In this work, a functionalized metal–organic layer (MTTB MOL) was first synthesized and characterized, where MTTB means that it was synthesized from TTB (4,4′,4″-s-triazine-2,4,6-triyl-tribenzoate). On this basis, a hybrid metal–organic framework of PCN-222(Co)@MTTB was further synthesized by combining two-dimensional (2D) MTTB MOLs and three-dimensional (3D) PCN-222(Co) MOFs (metal–organic frameworks) via a one-step method. When applied to the cycloaddition reaction of carbon dioxide (CO2) and epoxides, PCN-222(Co)@MTTB was found to exhibit excellent synergistic catalytic performance under mild conditions. The unique catalytic activity of the composite is due to the combination of the exposed acidic sites (Co2+, Zr4+) and basic sites (−N– groups) within the matrix of the MOF structure, thereby providing a new method for the exploration of effective catalysts for the conversion of CO2 to value-added chemicals under mild conditions.
研究领域:
材料科学
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催化
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化学工程
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环境化学
✓ 已验证
产品关联
DOI
危险品化学品经营许可证（带存储）