INORGANICA CHIMICA ACTA
·
2020
·
IF 2.304
Xue Dong,Yongcen Lin,Yuqin Ma,Lang Zhao
A post-synthetic approach using nitrogen-containing substances modify UiO-67 was proposed to enhance its adsorption for Congo red (CR). The newly synthesized materials were thoroughly analyzed by SEM, TEM, EDX, XPS, XRD, FT-IR, TGA and BET techniques. Results showed that N was successfully incorporated into UiO-67 frameworks to prepare of N X -UiO-67, through coordination interaction with Zr-O clusters. Compared to parent UiO-67, the obtained N X -UiO-67 exhibited a significant increase in adsorption of CR, and the adsorption capacities for CR were in the following order: N U -UiO-67 (2360 mg g −1 ) > N T -UiO-67 (1986.3 mg g −1 ) > N A -UiO-67 (1493 mg g −1 ). Moreover, the pseudo-second-order kinetics and the Langmuir isothermal model exhibited a better fit to describe the adsorption behavior of CR onto the N X -UiO-67.
研究领域:
材料科学
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环境化学
·
吸附技术
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产品关联
DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2023
·
IF 15.1
Mengshuo Du,Youyu Cao,Xueli Luo,Weixia Yang,Wanmei Lin,Yingying Wang,Wenzhi Tang,Zhonghong Li
Threats caused by heavy metal ions have prompted people to develop porous and functionalized materials to remove them. Metal–organic frameworks (MOFs) show potential for heavy metal ions removal due to the high specific surface area, tunable pore size, flexible designability and favorable stability. However, the intrinsic microporous structure and powder form limit their applications. Herein, we designed a shapeable aerogel bead incorporated with L-cysteine-modified defective UiO-67 for Pb(II), Cd(II) and Cu(II) adsorption. The pristine UiO-67 powders were firstly modified by introducing the modulator (octanoic acid) and an extra ligand (2,2′-bipyridine-5,5′-dicarboxylic acid) to construct defects, both of them competed with the original ligand to coordinate to Zr clusters, resulting in an increased BET surface area (from 337.66 to 1,037.14 m 2 /g) and mesoporous ratio (from 34 % to 74 %) of the pristine UiO-67. Then, the graft of L-cysteine containing –COOH and –SH introduced more active adsorption sites. Moreover, the powder material was incorporated into sodium alginate aerogel beads which enhanced the recyclability and further improved the adsorption capacity for Pb(II), Cd(II) and Cu(II). These appealing advantages endow the adsorbent with quicker adsorption equilibrium (240 min), and outstanding removal capacities for Pb(II) of 661.2 mg/g, Cd(II) of 296.2 mg/g and Cu(II) of 326.4 mg/g. The chelation and ions exchange between the numerous functional groups including –COOH, –OH and –SH and the heavy metal ions are the main mechanisms for effective adsorption. This work provided a novel approach for the application of MOFs in environmental remediation.
研究领域:
环境科学
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材料科学
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化学工程
·
水处理
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DOI
高影响因子
JOURNAL OF INORGANIC BIOCHEMISTRY
·
2025
·
IF 3.2
Anadil Gul,Munir Ahmad,Rizwan Ullah,Kamran Ullah,Wenchao Liao,Yan Kang
Metallophthalocyanines (MPcs) are highly promising photosensitizers owing to their exceptional photoelectronic properties, yet their practical photocatalytic applications are often limited by strong π–π self-aggregation. In this study, we report a facile in situ strategy to incorporate cobalt phthalocyanine (CoPc) into the porous matrix of UiO-67 metal-organic frameworks (MOFs), effectively suppressing aggregation and enhancing photo-activity. The resulting composite, UCoP2–32, exhibited outstanding antibacterial photodynamic therapy (APDT) performance under visible light, achieving over 96 % inactivation of methicillin-resistant Staphylococcus aureus (MRSA) within 12 min of light exposure. Photophysical studies confirmed the efficient generation of both type-I and type-II reactive oxygen species (ROS), with superoxide and hydroxyl radicals predominating, and electron spin resonance (ESR) analysis supported this mechanism. Moreover, UCoP2–32 demonstrated excellent biocompatibility with minimal hemolysis (~6.4 % at 110 μM) and structural stability. This work provides a robust and broadly applicable strategy for integrating MPcs into MOFs, offering significant potential for the development of high-performance photocatalytic materials in antimicrobial and other light-driven applications.
研究领域:
材料科学
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光动力治疗
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抗菌技术
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纳米技术
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无机化学
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生物医学工程
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产品关联
DOI
PubMed
高影响因子
BIOSENSORS & BIOELECTRONICS
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2018
·
IF 8.173
Xue Dong,Guanhui Zhao,Li Liu,Xuan Li,Qin Wei,Wei Cao
In this work, Ru(bpy) 3 2+ encapsulated in metal–organic frameworks (MOFs) UiO-67 (Ru(bpy) 3 2+ /UiO-67) as luminophor was easily prepared and firstly applied in constructing an electrochemiluminescence (ECL) immunosensor to efficiently estimate diethylstilbestrol (DES). The competitive method-based ECL immunosensor platform was fabricated by amino-silicon dioxide which possesses large surface area . The poriness of UiO-67 was splendid so that Ru(bpy) 3 2+ could be easily encapsulated. Ru(bpy) 3 2+ /UiO-67 with excellent ECL luminescence signal existed large specific surface area for easily labeled with antibodies. DES competed with bovine serum albumin-diethylstilbestrol (BSA-DES) for binding to antibody-specific sites in the constructed immunosensor. However DES was micromolecule, which was easier to bond to antibodies than BSA-DES. The ECL signal was gradually decreases with the increase of the concentration of DES. Under optimal conditions, the proposed immunosensor exhibited a wide linear range from 0.01 pg mL −1 to 50 ng mL −1 with a low detetion limit of 3.27 fg mL −1 (S/N = 3). The novel fabricated immunosensor with interference immunity and high stability may cause an attractive approach for the other targets determination.
研究领域:
分析化学
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环境科学
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生物技术
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DOI
高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
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2017
·
IF 5.401
Xin Zhang,Ke Jiang,Huajun He,Dan Yue,Dian Zhao,Yuanjing Cui,Yu Yang,Guodong Qian
A fluorescent pH sensor based on post-synthetically modified nanoscale UiO-67-bpydc by encapsulating Eu 3+ cations in the pores was fabricated. The Eu 3+ incorporated sample (Eu 3+ @UiO-67-bpydc) shows excellent luminescence due to the sensitization and protection provided by the parented framework. Subsequently, Eu 3+ @UiO-67-bpydc was developed as a pH sensor. Eu 3+ @UiO-67-bpydc shows good chemical resistance to both acidity and alkalinity solutions with pH ranging from 1.06 to 10.99, which makes it potentially useful for wide-range pH sensor. In addition, cycling experiments have demonstrated the utilizability of the sensor. The MTT analysis shows that Eu 3+ @UiO-67-bpydc possesses favourable biocompatibility. Furthermore, fluorescence imaging of Eu 3+ @UiO-67-bpydc in PC12 cells was also performed to test its feasibility in vivo. Given its exceptional stability and pH-dependent fluorescent intensity, the fluorescent probe should be a promising candidate for application in fluorescent pH sensing in vitro and in vivo.
研究领域:
材料科学
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生物医学工程
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分析化学
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DOI
高影响因子
JOURNAL OF FLUORESCENCE
·
2020
·Vol. 30
·期 3
·427-435
·
IF 2.093
Ruan Bo,Liu Huan-Li,Xie Lei,Ding Hui,Zhang Ya,Wu Jin,Huang Zhe,Shi Dean,Jiang Tao,Tsai Fang-Chang
Sulforhodamine B (SRB) is widely utilized for cell staining and laser field. But its application is limited by aggregation-caused quenching (ACQ). In this work, we evaluated the use of UiO-66 and UiO-67 of Zr-based metal organic frameworks (Zr-MOFs) as the host to adsorb SRB molecules due to the high stabily and good loading capacity of Zr-MOFs. The fluorescence properties of the compounds were then discussed respectively. Due to the aperture difference between UiO-66 and UiO-67, they showed distinct fluorescence properties after loading SRB. When the concentration reaches 5 ppm, fluorescence quenching begins to occur in SRB@UiO-66, while it occurs in SRB@UiO-67 at 2 ppm. The solution of quenching phenomenon could open new avenues for the extensive use of SRB.
研究领域:
材料科学
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生物医学
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产品关联
DOI
PubMed
高影响因子
Nanomaterials
·
2025
·Vol. 15
·期 11
·826
·
IF 4.3
Zan Cheng,Mei Yu,Yilong Wan,Huandong Xiang,Haoran Wei,Xu Zu,Xin Li,Ruiting Zhang,Fangshu Li,Shanshan Wang,Yongxin She
Metal–organic frameworks (MOFs) have great potential for drug delivery systems due to their tunnel pore size, structural versatility, and high surface area. Among them, UiO-67 have recently attracted substantial attention as functional nanocarriers for effective delivery of small molecule chemical drugs. However, the influence of the size on cellular uptake of UiO-67 remains ambiguous. Here, we use polyvinyl pyrrolidone (PVP) as the capping agent of UiO-67 to synthesize spherical Zr-based MOFs with various diameters, including 40 nm, 60 nm, and 120 nm. The highest cellular uptake is observed in the case of Zr-based MOFs with a diameter of 40 nm (PU 40 MOFs). Moreover, doxorubicin can be loaded into the inner pores of PU 40 MOF via π-π and electrostatic interactions (DPU 40 MOFs), with a loading capacity of 82 wt%, and gradually released under acidic conditions. In vitro, the resulting DPU 40 MOFs can be internalized by cancer cells more effectively, thereby enhancing the delivery of doxorubicin into cancer cells. Ultimately, this results in enhanced antitumor efficacy toward 4T1, Hs 578T, and MCF-7 cells. Our findings indicate that approximately 40 nm may be the optimum diameter for the special Zr-based MOFs to be internalized by cells more effectively, providing potent potential nanocarriers for drug delivery.
研究领域:
药剂学
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肿瘤学
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纳米医学
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产品关联
DOI
PubMed
高影响因子
MICROPOROUS AND MESOPOROUS MATERIALS
·
2021
·
IF 5.455
Mengmeng Zhang,Jiaying Lou,Rui Xu,Peng Li,Yunfei Sha,Hui Zhang,Yu Jia,Zhenxia Chen,Da Wu,Yun Ling,Yaming Zhou
Metal-organic frameworks (MOFs) featuring a fcu-type net based on 12-connected [Zr 6 (μ 3 -O) 4 (μ 3 -OH) 4 ] cluster have received considerable interest for the fundamental investigation of structure-property relationships in a wide range of catalytic reactions . In this work, the bipyridine (bpy) chelate group was introduced into the fcu-type framework of UiO-67, giving UiO-67bpy as the catalyst support. Then, FeCl 3 was post-synthetically anchored to the bpy group, resulting into the isolation of FeCl 3 /UiO-67bpy. Catalyzed hydrolysis of 5-hydroxylmethoxyfurfural (HMF) into levulinic acid (LA) was then explored and revealed that it can efficiently and selectively catalytic convert HMF into LA, which is superior to that of FeCl 3 /UiO-67 where FeCl 3 is encapsulated in the cage of UiO-67 and dispersed on the pore surface. The recyclability studies further confirmed the importance of anchored FeCl 3 where there is no significant decrease in catalytic activity as compared with that of FeCl 3 /UiO-67. Taking the detailed textural porosity and catalytic results of isomorphous structures in consideration, our studies revealed that narrowing the pore size with anchored FeCl 3 on the skeleton of the fcu-type Zr-MOF rather than encapsulating FeCl 3 inside the cage is more favored for the rehydration reaction of HMF to LA.
研究领域:
化学
·
材料科学
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产品关联
DOI
高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
·
2023
·
IF 8.6
Shushu Jia,Ping Lin,Yue Li,Yakun Teng,Jing Wang,Tianyi Yang,Lijuan Li,Ce Wang,Xiang Li
The efficient removal of pharmaceutical pollutants in groundwater has become an urgent issue in sewage treatment. β-cyclodextrin (β-CD), a polysaccharide and rich in raw materials, has broad applications in adsorption and separation due to its host–guest interaction with many molecules. In this paper, a flexible and water-insoluble UiO-67(Zr)-modified cyclodextrin-based nanofiber membrane (UiO-67@β-CD-NP) was synthesized via a combination of electrospinning and solvothermal methods. By virtue of the synergetic adsorption effect of cyclodextrin and MOFs, the UiO-67@β-CD-NP shows excellent performance for ibuprofen (IBP) removal. The adsorption of IBP onto UiO-67@β-CD-NP was well-fitted with the pseudo-second-order kinetic model and Freundlich isothermal model, yielding an adsorption capacity of 226.24 mg/g. Furthermore, the UiO-67@β-CD-NP nanofibers demonstrate a high removal rate of 100 % and exhibit good regenerability in dynamic adsorption experiments. After the filtration of UiO-67@β-CD-NP, the chemical oxygen demand (COD) concentration of IBP has evidently reduced below the discharge standard of pharmaceutical sewage. This study provides a simple and novel strategy for preparing low-cost and high-performance composite nanofiber membrane incorporating cyclodextrin and MOFs. This membrane holds great potential as a candidate for adsorption applications in practical pharmaceutical sewage treatment.
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DOI
高影响因子
MICROPOROUS AND MESOPOROUS MATERIALS
·
2019
·
IF 4.182
Ji-Min Yang,Bao-Chan Yang,Yan Zhang,Rui-Ning Yang,Shan-Shan Ji,Qiang Wang,Shuai Quan,Run-Zhi Zhang
Porous metal–organic frameworks (MOFs) exhibit excellent characteristics for the adsorptive removal of environmental pollutants. Herein, the surface charge, adsorption sites, and adsorption spaces in the pore channels of UiO-67 nanocrystals were modulated by Ce(III) doping to reveal the effects of these parameters on the removal of organic dyes such as methylene blue (MB), methyl orange, and Congo red from aqueous solution. The MB adsorption capacity of Ce(III)-doped UiO-67 (398.9 mg g −1 ) exceeded that reported for pristine UiO-67 by 85%, which was rationalized by zeta potential measurements and adsorption isotherm analyses. As a result, it was revealed that whereas electrostatic repulsion occurred between MB and pristine UiO-67, electrostatic attraction occurred between MB and Ce(III)-doped UiO-67. Furthermore, Ce(III) doping promoted π–π interactions between the adsorbent and the adsorbate. Thus, Ce(III) doping increased MB adsorption capacity despite decreasing the number of adsorption sites and spaces in channels. The obtained results shed light on the mechanism of organic dye adsorption on MOFs and revealed that the synergetic interplay of electrostatic and π–π interactions, adsorption sites, and adsorption spaces increases the adsorption capacity for cationic dyes while decreasing that for anionic dyes.
研究领域:
环境科学
·
材料科学
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产品关联
DOI
高影响因子
JOURNAL OF CHROMATOGRAPHY A
·
2020
·
IF 4.049
Lian Xia,Yanan Dou,Jie Gao,Yumeng Gao,Wenjing Fan,Guoliang Li,Jinmao You
In this work, a dispersive solid phase extraction (d-SPE) method for sulfonamides (SAs) has been developed using a stable and mesoporous metal organic framework (University in Oslo 67, UiO-67) as adsorbent, which was synthesized by coordination of Zr 4+ ions with 4, 4-biphenyl-dicarboxylicacid (H 2 BPDC) through a facile one-pot method. Owing to the synergistic effects of π-π interaction, hydrogen bonding , hydrophobic interaction and size match between SAs and the adsorbent, the extraction performance of UiO-67 for SAs was obviously improved. The adsorption behavior , evaluated by the kinetic models , showed that the intraparticle diffusion was involved during the adsorption process. The proper match between the pore size of UiO-67 (3.49 nm) and the molecular sizes of SAs (1.1 nm × 0.65 nm) not only allowed SAs to diffuse intraparticle but also permitted them to adjust their configurations to form hydrogen bonding with the UiO-67. By combination with HPLC analysis, a simple, sensitive, accurate and precise method for detection of SAs has been established. The method proposed in this work showed good performances, including wide linearity (14.6–250 ng/g) with high correlation coefficients ( R ≥ 0.9991), low limits of detection (LODs, 0.7–6.5 ng/g for all SAs), satisfactory precision (Intra-day RSDs ≤ 3.4%, inter-day RSDs ≤ 4.7%), and high accuracy (recovery: 83.4–103.8%). Furthermore, benefiting from the mesoporous structure and the Zr cluster center as well as the stability, UiO-67 shows great potential to be an excellent adsorbent of SPE for extraction of SAs from other complex matrices.
研究领域:
分析化学
·
食品科学
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DOI
高影响因子
ACS Applied Materials & Interfaces
·
2019
·
IF 8.456
Xueyun Li,Bo Li,Mingchen Liu,Yufeng Zhou,Liyuan Zhang,Xiaoqiang Qiao
Stationary phases with mixed-mode mechanisms have emerged as a hot research topic. In the present research, monodisperse core–shell UiO-67@SiO2 materials were prepared and further served as the packed column for mixed-mode hydrophilic interaction liquid chromatography/reversed-phase liquid chromatography. The developed UiO-67@SiO2 materials were characterized via thermogravimetric analysis, scanning electron microscopy, X-ray Powder diffraction, and Fourier transform infrared techniques. The developed UiO-67@SiO2 column shows flexible selectivity for separation of both hydrophobic (anilines, alkylbenzenes, and polycyclic aromatic hydrocarbons) and hydrophilic (thioureas) compounds. Furthermore, the UiO-67@SiO2 column was also utilized to characterize potential pollutants in lake water samples. In summary, the UiO-67@SiO2 column provided flexible selectivity and wide-range retention behaviors for both hydrophilic and hydrophobic analytes.
研究领域:
分析化学
·
材料科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）