JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY
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2015
·Vol. 15
·期 12
·9887-9891
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IF 1.556
Yuan Lin,Li Zhong Yan,Zhang Xing Yu,Li Wen Yi,Zhang Min,Yuan Xian You
A new chiral 1,3-dioxane compound was synthesized by aldol condensation reaction in this paper. The reaction of cinnamic aldehyde with 2.1 equiv. of 2,2-bis(hydroxymethyl) butanol in N, N-dimethylformamide and cyclohexane, nanosolid superacid SO2-
4/Fe2O3
was applied as catalyst, afforded the new chiral 1,3-dioxane compound (E)-(5-ethyl-2-styryl-1,3-dioxan-5-yl) methanol. The compound was fully characterized with infrared spectra, elemental analysis, melting points, 1H NMR and X-ray diffraction. Single crystal X-ray diffraction analysis revealed
that the compound crystallized in the monoclinic system, space group P2(1) with a = 5·717(2) Å, b = 11·684(4) Å, c = 10·569(4) Å, α = 90·00°, β = 99·646(4)°, γ = 90·00°,
V = 696·0(4) Å3, Z = 2, Dc = 1·185 g/cm−3, R = 0·0182, μ = 0·081 mm−1, F(000) = 268. In addition, the antibacterial activities of the compound against Bacillus subtilis, Escherichia
coli and Staphylococcus aureus have been investigated.
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DYES AND PIGMENTS
·
2016
·
IF 4.055
Yahui Zhang,Huiling Mao,Lingwei Kong,Yong Tian,Zhonglin Tian,Xiangkai Zeng,Junge Zhi,Jianbing Shi,Bin Tong,Yuping Dong
E/Z isomers of hexaphenyl-1,3-butadiene (HPB) derivative containing dialdehyde groups, 4,4’-((1E,3E)-1,2,3,4-tetraphenylbuta-1,3-diene-1,4-diyl)dibenzaldehyde (EE-HPB-CHO), 4,4’-((1Z,3E)-1,2,3,4-tetraphenylbuta-1,3-diene-1,4-diyl)-dibenzaldehyde (EZ-HPB-CHO) and 4,4’-((1Z,3Z)-1,2,3,4-tetra-phenylbuta-1,3-diene-1,4-diyl)dibenzaldehyde (ZZ-HPB-CHO), were firstly synthesized in one-pot and readily separated by silica gel column chromatography . The E/Z isomers containing conjugated diene exhibited remarkable differences in the fields of aggregation-induced emission (AIE) or aggregation-enhancement emission (AEE) behavior, thermostability, and mechanochromic performance. Among them, EE-HPB-CHO with dense molecular packing and strong intermolecular interaction was a better AIEgen while the EZ- and ZZ-isomers exhibited AEE behavior. Moreover, EE-HPB-CHO hardly displayed the mechanochromic performance. EZ-HPB-CHO irreversibly exhibited a blue-shift of 23 nm by grinding treatment, which could not be restored by fuming with organic solvents or heating. In contrast, owing to its twisting conformation and relative loose packing, ZZ-HPB-CHO reversibly displayed a red-shift of 20 nm during multiple repeating cycles of grinding and fuming treatments, showing superior mechanochromic performance.
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CHEMICAL ENGINEERING JOURNAL
·
2019
·
IF 8.355
Jun Song,Xiaohui Wu,Meng Zhang,Cheng Liu,Jianyong Yu,Gang Sun,Yang Si,Bin Ding
Functional semiconductor nanomaterials modified TiO 2 fibrous membranes with desirable heterostructures, good mechanical properties, and superior visible-light-driven photocatalytic activity would have broad applications in environmental remediation; however, constructing such fantastic fibrous membranes still remains an enormous challenge. Herein, we fabricated a soft and heterostructured g-C 3 N 4 @Co-TiO 2 (CNCT) nanofibrous membranes by a facile electrospinning approach and subsequent thermal polymerization process. The ultrathin g-C 3 N 4 nanoshell was in situ synthesized and uniformly wrapped onto Co-TiO 2 nanofiber to form core-shell quantum heterojunction , and the thickness and loading amount of g-C 3 N 4 nanoshell can be precisely controlled through simply regulating the content of precursor (melamine). Benefiting from the three-dimensional porous networks, enhanced visible-light response, and the effective charge transfer induced by uniform and compact heterojunction, the as-synthesized CNCT membranes exhibited a prominent photodegradation efficiency of 90.8% within 60 min towards tetracycline hydrochloride, and also displayed excellent antibacterial performance with a 6 log inactivation of E. coil after 90 min visible light exposure. Moreover, the stable core-shell structures and robust mechanical strength also endow the membranes with favorable reversibility and easy-recycling ability. This study may open up new avenues for designing and constructing flexible high-performance photocatalytic membranes for water purification.
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Marine Drugs
·
2026
·Vol. 24
·期 11
·378
·
IF 5.7
A-Long Zhang,Yan-Qing Guo,Zheng-Biao Zou,Xian-Wen Yang,Chun-Lan Xie
Chemical investigation of the deep-sea-derived fungusPenicillium maliMCCC 3A00140 afforded two new compounds, penimeroandranoid E (1) and malistatin (2), together with 16 known ones (3–18). Their structures were established by extensive spectroscopic analyses, including 1D and 2D NMR and HRESIMS. The relative configuration of1was supported by single-crystal X-ray diffraction, and its absolute configuration was assigned by comparison of the experimental and calculated electronic circular dichroism (ECD) spectra. Compound1was the meroterpenoid reported to possess a 6/6/6/5 spirocyclic framework—a spiro-fused variant of the 6/6/6/5 carbocyclic system that was characteristic of andrastin-type DMOA-derived meroterpenoids—and its structure and relative configuration were established by single-crystal X-ray diffraction. The stereochemical assignment of2was based on NOESY correlations and biosynthetic analogy with related statins. Screening of all isolates at 20 μM in a receptor activator of nuclear factor-κB ligand (RANKL)-induced osteoclastogenesis model using primary murine bone marrow-derived macrophages identified1as the bioactive secondary metabolite. Compound1reduced the formation of tartrate-resistant acid phosphatase-positive multinucleated osteoclasts at 12.5–50 μM without decreasing cell viability after 48 h at concentrations up to 50 μM. These findings expand the chemical diversity of fungal meroterpenoids and identify1as a structurally distinctive anti-osteoclastogenic metabolite warranting further mechanistic investigation.
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ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
·
2026
·
IF 3.5
Margarita A. Arbuzova,Olga Yu Selyutina,Nikolay E. Polyakov
Cholesterol drives E-protein depth redistribution via a matrix-mediated helix tilt adjustment. • Escin-induced peptide localization shifts strictly require the presence of charged DMPS lipids. • Escin is hypothesized to modulate the viroporin conformation via localized helix kinking rather than matrix disruption. • Escin is able to extract cholesterol from lipid membrane. β-Escin is a well-known saponin derived from the horse chestnut tree. Saponins, including escin, exhibit a wide range of biological activities, among which membrane-modifying activity is particularly notable. The latter is key to understanding the molecular mechanisms underlying escin's biological effects, including its antiviral properties. For example, altering membrane properties can strongly influence the life cycle of enveloped viruses such as SARS-CoV-2 by modulating the activity of its envelope protein (E protein). In the present paper, we studied the localization of both escin and the E protein transmembrane domain (ETM) in model membranes with different lipid compositions. We demonstrated that escin can alter ETM localization in membranes containing the negatively charged lipid DMPS, and that escin is also capable of extracting cholesterol from model lipid membranes. Download: Download high-res image (423KB) Download: Download full-size image
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Journal of Mechanical Science and Technology
·
2026
·
IF 2.2
Khalil Muhammad Kaleem Ullah,Gul Rizwan M.,Shah Nouman Ali,Jan Syed Rooh Ullah,Ahmad Adnan,Kamran M. Ali,Xu Jia-Zhuang,Li Zhong-Ming
Wear and oxidation resistance are among the primary requirements for successful and sustainable total joint replacements (TJRs). Both of these factors are major causes of TJRs failure. To address these issues and enhance the service life of TJRs, the effects of vitamin E (VE) and vitamin E-D-sorbitol (VE-DS), which are antioxidants (AOs), on stabilizing ultrahigh-molecular-weight polyethylene (UHMWPE) are presented. These antioxidants were blended with control-UHMWPE at a concentration of 0.3 % by weight and consolidated by compression molding. Wear occurs on the surface, and restricting the crosslinking to a layer on the surface is desirable, as bulk crosslinking reduces the toughness and fatigue strength of the implant. In this study, surface chemical crosslinking of control-UHMWPE, VE-UHMWPE and VE-DS-UHMWPE with dicumyl peroxide (DCP) is presented. The crosslinked density, crystallinity, wear volume, mechanical performance, biocompatibility and oxidation stability assessed by oxidation induction time (OIT) of the UHMWPE blends were characterized through different techniques. The control-UHMWPE blend showed the highest wear resistance but the lowest OIT, while the VE-DS-UHMWPE blend displayed highest crystallinity, best mechanical performance and the highest OIT, exhibiting the synergistic effect of vitamin E and D-sorbitol on the oxidation resistance of UHMWPE.
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FOOD RESEARCH INTERNATIONAL
·
2026
·
IF 8.8
Ke Han,Jiankang Ren,Boyan Sun,Xiaomei Wang,Qian Ran,Haiyang Jiang
A novel phage HH3 of E. coli was isolated and characterized. • A colorimetric sensor was developed for E. coli detection within 35 min. • The biosensor shows high sensitivity and accuracy in various food and water matrices. • The biosensor exhibited a wide linear range and a low LOD of 3.2 CFU/mL. • It distinguishes viable E. coli from dead cells, beyond conventional methods. A phage HH3-functionalized Ce-UiO-66-NH₂ nanozyme-based colorimetric biosensor was developed for the quantification of viable Escherichia coli ( E. coli ), overcoming the drawbacks of slow detection and inadequate live/dead bacterial discrimination in conventional analytical methods. The proposed platform achieves target detection within 35 min, with a low limit of detection (LOD) of 3.2 CFU/mL and satisfactory spiked recoveries ranging from 82.75% to 122.06%. Mechanistically, Ce-UiO-66-NH₂ exhibits intrinsic oxidase-like activity that directly catalyzes the oxidation of 3,3′,5,5′-tetramethylbenzidine (TMB) to blue-colored oxTMB. The color intensity of this chromogenic reaction is positively correlated with E. coli concentration, enabling quantitative analysis. Benefiting from the specific recognition capability of phage HH3, the biosensor shows negligible responses to non-host bacteria and heat-inactivated E. coli . This distinctive advantage cannot be achieved by antibody- or PCR-based strategies. This nanozyme-phage platform outperforms most reported sensors and possesses promising potential for rapid and selective quantification of viable E. coli in complex food and environmental matrices. Download: Download high-res image (252KB) Download: Download full-size image
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CHEMICAL ENGINEERING JOURNAL
·
2026
·
IF 12.5
He Zhao,Chu Xu,Caobin Zhou,Ling Zhang,Chunzhong Li
Existing triboelectric nanogenerators (TENGs) for wearable sweat sensors are plagued by low power density, which restricts their practical application. This study focuses on boosting TENGs output power via a fluorinated bi-layer electronic textile (e-textile) fabricated by electrospinning rotary collection, enabling self-powered dual functionality: real-time electrochemical sweat sensing and human motion detection. The key design includes a PCLU-HFDD negative triboelectric layer (molecularly incorporated with hexadecafluorodecanediol to enhance electron affinity) and a poly(lactic- co -glycolic acid) (PLGA) positive layer. Rotary collection creates vein-like nanostructures on PCLU-HFDD yarns (6.2 μm roughness, 114.8° water contact angle), increasing contact area. The PCLU-HFDD TENG achieves a high power density of 0.66 W m −2 , an open-circuit voltage (Voc) of 117.08 V, and excellent stability over 35,000 contact-separation cycles. Critically, integrated with both sweat-sensing and motion-detection capabilities, the e-textile enables 180-min continuous glucose monitoring (under sedentary conditions) and recognition of human motions. This work confirms that the power enhancement not only overcomes the bottleneck of TENGs for wearable sensors but also facilitates dual-modal health monitoring, advancing the development of practical wearable bioelectronics.
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Advanced Sustainable Systems
·
2019
·Vol. 3
·期 5
·1900026
·
IF 0
Yanyan Wang,Xue Yu,Gen Liu,Xiaodong Zhu,Rui Xu,Mei Ji,Yanqing Ma,Lei Ma
Proton exchange membrane water electrolysis (PEMWE) is known as an effective and environmental-friendly method for hydrogen production. However, the process is hindered by the necessity of large loading of high-priced noble metals in the conventional approaches. To resolve this problem, a highly efficient Nafion-based catalyst and proton exchange system are developed, which only need ultralow platinum loading by direct e-beam evaporation deposition. Scanning electron microscopy is performed before and after the deposition, which reveals a very smooth morphology. By assembling the PEMWE device with above-mentioned cathode and conventional iridium black anode, the current density reaches 500 mA cm −2 with a platinum loading of only 0.00379 mg cm −2 at 1.64 V under 80 °C. A mass activity of ≈132 A mg −1 is achieved, which is one order of magnitude higher than previously reported results. Moreover, powered by a commercial silicon solar cell, it realizes a solar-to-hydrogen conversion efficiency up to 8.26%. This work opens up an avenue of fabricating PEMWE with an ultralow catalyst loading, which may have enormous potential for future industrial scale applications.
研究领域:
能源材料
·
电化学
·
氢气生产
·
薄膜沉积
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Biomolecules
·
2026
·Vol. 16
·期 1
·152
·
IF 4.8
Zeyan Xu,Chuyu Qin,Ruohan Zhang,Mengting Wu,Anqi Cui,Wei Chen,Lu Chen,Daqing Gao,Ruihua Shi
Adherent-invasiveE. coli(AIEC) is closely related to inflammatory bowel disease (IBD). However, its pathogenic mechanism has not yet been fully elucidated. Using a BLASTP search, we discovered that the amino acid sequence of a putative protein (UFP37798.1) in the AIEC LF82 strain is highly homologous to some regulators in the SlyA family. We named it EruA. We displayed the secondary structures of EruA using bioinformatics, overexpressed the His6-tagged EruA protein using SDS-PAGE, and dissected the genetic organization of theeruAchromosomal region using 5′RACE. We constructed aneruAdeletion mutant (ΔeruA) and a complementary strain (CΔeruA) of the LF82 strain. The transcriptomes of wild-type (WT) and ΔeruA bacteria were compared using RNA sequencing and qRT-PCR, thereby identifying 32 differentially expressed genes (DEGs). Based on YASARA software and EMSA analysis, EruA directly binds to the consensus sequences (PfimAand PtnaB) in the promoter region of thefimAandtnaBgenes from these DEGs. By using a super-resolution confocal microscope (SCM), counting CFUs of colonies on plates, indole quantification, and crystal violet staining of biofilms adhered to tubes or 96-well plates, we found that EruA activates thefimAto promote bacterial adhesion to intestinal epithelial cells and activates thetnaBto enhance bacterial indole production and biofilm formation. Moreover, EruA helps AIEC resist environmental stress and enhances bacterial survival within macrophages as well as loading in mouse tissues. Notably, EruA promotes AIEC colonization in the colons of mice and exacerbates intestinal inflammation caused by bacterial infection in mice with DSS-induced inflammatory colitis, manifested by weight loss, colon length shortening, and pathological changes in colon tissues. Therefore, EruA plays a key role in the pathogenicity of AIEC.
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Frontiers in Chemistry
·
2026
·
IF 5.3
Pengfei Yang,Lingqi Kong,Qiongbo Wang,Qiang Liu,Xiujin Duan,Chen Hu,Zhengbo Feng,Qi Yang,Huabo Jv
Introduction To investigate the impact of different processing methods on the volatile components in Aglaia odorata flower extract (AOFEs). Methods Headspace solid-phase microextraction coupled with gas chromatography-mass spectrometry and electronic nose (E-Nose) analysis were employed to characterize volatiles of extracts obtained by ultrasound-assisted extraction (UAE), microwave-assisted extraction (MAE), and heated reflux extraction (HRE). Multidimensional assessment using aroma radar charts, orthogonal partial least squares-discriminant analysis (OPLS-DA), K-means clustering, and relative odor activity value (ROAV) revealed significant processing-dependent variations. Results and discussion The results indicated that the fiber coated with DVB/CAR/PDMS had optimal extraction efficiency. A total of 46 compounds were identified, including eight alcohols, four aldehydes, one acid, 25 terpenes, seven ketones, and one heterocyclic compound. UAE and MAE had 36 and 38 compounds respectively, sharing similar compositional profiles but differing in concentrations, while HRE produced only 25 compounds Sensory evaluation and E-Nose results revealed differences in the aroma profiles of the extracts, with UAE and MAE extracts exhibiting intensified floral and sweet notes, whereas HRE displayed prominent green and spicy characteristics. K-means clustering categorized volatile evolution trends into four distinct subclasses. OPLS-DA identified 13 differential volatiles with variable importance in projection greater than 1, with ROAV analysis further selecting eight key markers, including (1R,7 S )-germacra-4(15),5,10(14)-trien-1 β -ol, α -humulene, copaene, β -cadinene, (E)- β -caryophylene, Γ -cadinene, humulene oxide II, and caryophyllene oxide. These compounds collectively contribute to the sweet and floral attributes of AOFEs. This study elucidated extraction-method-dependent volatile profiles and aroma characteristics, providing theoretical guidance for process optimization and quality enhancement in AOFEs production.
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INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
·
2025
·
IF 3.9
Dengliang Cai,Guangxin Zhao,Wenan Tie,Ting Lei,Jiachun Feng
Polypropylene (PP) combines excellent mechanical properties with cost-effectiveness, yet its practical applications are hindered by poor thermo-oxidative resistance and slow crystallization kinetics. While conventional antioxidants and nucleating agents can mitigate these issues, increasing safety concerns over synthetic additives have spurred interest in natural alternatives. However, natural antioxidants such as vitamin E (VE) often exhibit inadequate stabilization at low loadings, and few industrially available biobased nucleating agents were developed. Here, we reported that myo-inositol (Ins), a bioderived compound, acted as a dual-functional additive, simultaneously improving both the thermo-oxidative stability and crystallization behavior of VE-containing PP. Incorporating 0.2 wt % Ins into PP stabilized with 0.1 wt % VE dramatically extended the oxidation induction time from 7.5 to 45.3 min, indicating strong synergistic antioxidant activity. Furthermore, Ins enhanced crystallization kinetics, increasing the peak crystallization temperature by 5.4 °C (10 °C/min cooling rate) and reducing the half-crystallization time by 69% during isothermal crystallization at 120 °C compared to VE-only PP. The dual role of Ins was attributed to its function as a metal chelator and a heterogeneous nucleation agent, offering a sustainable strategy for high-performance PP modification.
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