CHEMICAL PAPERS
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2026
·
IF 2.7
Weng Xuling,Guo Fang,Zhong Yu,Feng Wanyun,Shang Xiaoqiang,Chen Yufeng
A drug delivery system based on magadiite for gemcitabine (namely GEM-Mag) has been constructed by protonation, intercalation with tetrabutylammonium ions (TBA + ), and ion exchange. Various measurements were used to characterize the samples. XRD results showed that the basal spacing of Na-magadiite (15.17 Å) decreased to 11.40 Å after protonation. Following intercalation with TBA + , the basal spacing increased to 25.79 Å. After further ion exchange with the positively charged GEM, the basal spacing reduced to 18.21 Å. FT-IR and TG-DTG indicated that the GEM was incorporated into the magadiite. Based on CHN elemental analysis and EDS results, the chemical formula of GEM-Mag was estimated to be H 1.59 (C 9 H 12 F 2 N 3 O 4 ) 0.41 Si 14 O 29 ·2.33H 2 O. According to the chemical formula, the loading capacity of GEM-Mag for GEM was 10.74%. Drug release tests were carried out either in phosphate buffered solution (PBS, pH = 7.40) or in HCl solution (pH = 1.35). Results revealed that the GEM-Mag exhibited sustained-release of GEM. While the drug released for 96 h in the PBS, the cumulative release percentage of GEM from drug delivery system was only 53.46%; whereas in the HCl solution (pH = 1.35), the cumulative release percentage was 52.15% after 700 min. Cytotoxicity assay confirmed that the magadiite-based drug delivery system for GEM exhibited stronger inhibitory effects on HepG2 cells compared with that of the free GEM. In addition, the drug-loading process and mechanisms have been discussed in detail.
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高影响因子
NEUROCHEMICAL RESEARCH
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2026
·Vol. 51
·期 4
·237
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IF 4.5
Han Zhipeng,Li Xing,Yang Li,Li Jinglin,Zhao Kaiyang,Xie Junxiong,Zhou Siyuan,Shi Wenli,Zhang Xiaolina
Neuropathic pain (NP) is chronic pain caused by injury or disease affecting the nervous system. SIN@Lip-HA was prepared and characterised for particle size, zeta potential, encapsulation efficiency and morphology. Sprague-Dawley rats with spared nerve injury (SNI) were randomly divided into the six groups. Analgesic effects were assessed via behavioural tests. Histopathological changes were examined using H&E staining. Astrocyte polarisation was detected using immunofluorescence, and Western blotting was used to assess related protein expression. qRT-PCR measured mRNA level of genes, while ELISA evaluated inflammatory cytokines and oxidative stress markers. The study showed that the particle size of SIN@Lip-HA was 111 ± 5.13 nm, with an encapsulation efficiency of 85.47% and a zeta potential of -24.86 ± 1.20 mV. The in vitro release profile showed sustained drug release, and the formulation remained stable for 3 months. Compared with the model group, SIN@Lip-HA significantly increased PWT and PWL, alleviated spinal cord pathology and was associated with a shift in astrocyte reactivity, as indicated by a reduction in A1-related markers and an increase in A2-related markers. SIN@Lip-HA downregulated CGRP/SP and GFAP. It was also found to inhibit JAK2/STAT3 pathway activation by reducing p-JAK2/p-STAT3 expression and decrease TNF-α, IL-1β and IL-6 whilst increasing IL-10. It also mitigated oxidative stress. Concomitant use with gabapentin markedly enhanced therapeutic efficacy. These findings suggest that sinomenine liposomes alleviate NP in SNI rats in a manner associated with inhibition of JAK2/STAT3 signaling and correlated with astrocyte reactivity, and reduced pain mediators.
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Journal of the Iranian Chemical Society
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2026
·Vol. 23
·期 9
·283
·
IF 2.4
Wu Rui,Tian Guanghui,Liu Cunfang,Li Yapeng
The controlled synthesis of hybrids nanoparticles (NPs) and polymer have received significant attention for application in environment. In the paper, green and multifunctional polymer-based Fe 3 O 4 /hydroxyapatite (HAp)/polyacrylic acid (PAA)/ polyacrylamide (PAM) nanohybrids with magnetism was fabricated by polymerization. The obtained materials (Fe 3 O 4 /HAp/PAA/PAM) was characterized by hysteresigraph, X-Ray diffractometer (XRD), infrared spectrometer (IR), energy dispersive spectroscopy (EDS), mapping, scanning electron microscopy (SEM), transmission electron microscopy (TEM), X-ray photoelectron spectroscopy (XPS), vibrating sample magnetometer (VSM). The decontaminating performance of the nanohybrids was evaluated by adsorption methylene blue (MB). Adsorption kinetics and adsorption isotherms were employed to examine the adsorption behavior. The results showed that the adsorption process fitted the Langmuir isotherm and pseudo-second-order kinetic model and Fe 3 O 4 /HAp/PAA/ PAM displayed appreciable adsorption efficiency. The adsorption mechanism was also presumed. The removal of dye mainly attributed to polymer with multifunctional groups and the special structure of HAp. Moreover, it is facile to retrieve due to the incorporation of Fe 3 O 4 with strong magnetism. It proposed a novel route to design and fabricate multifunctional nanohybrid adsorbent for removal of dye with high capacity.
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高影响因子
Nature Communications
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2026
·
IF 18.1
Chu Zhaomiao,Zhou Zicong,Jin Keao,He Linghui,Li Chuang
Reconfiguring handedness in synthetic systems with spatiotemporal control and reversible behavior remains a fundamental challenge in bioinspired robotics and materials science—especially in structurally homogeneous materials that lack intrinsic chirality. Here, we demonstrate homogeneous photoactive hydrogels capable of ultrafast, programmable handed shape-morphing, including helices and twists, through spatially controlled light illumination. This transformation is driven by a photoexpansion exceeding 80,000% volumetric growth within 40 seconds, enabled by the synergistic combination of spiropyran photoisomerization and tailored polymer-network interactions. Deterministic strain mismatches at illuminated interfaces allow on-demand forming and shaping of handed architectures, which can be erased in darkness and reprogrammed reversibly with light. We further synchronize opposing handedness and complex tendril-like geometries in a single material, and exploit handedness to achieve self-propelled rotation for robotic locomotion. This work introduces a versatile method for adaptive, lifelike chirality in homogeneous matter, closing a key gap between biological shape-morphing and engineered soft robotics.
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高影响因子
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
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2026
·
IF 4.1
Xue Jun-Chang,Jiang Yue,Xia Huan,Hou Lu,Li Heng-Ye,Wang Zhong-Xia,Kong Fen-Ying,Wang Wei
An electrochemical sensor was developed for the sensitive voltammetric determination of 4-nitrophenol (4-NP) by integrating an in situ grown nanocomposite of amino-functionalized carbon nanotubes (NH 2 -CNTs) and a zinc porphyrin-tetrathiafulvalene covalent organic framework (TTCOF-Zn). This hybrid design strategically couples the electron donor–acceptor (D-A) architecture of TTCOF-Zn, featuring pre-engineered electron transport channels, with the exceptional electrical conductivity of NH 2 -CNTs via covalent bonding, synergistically enhancing charge transfer efficiency. Leveraging the high conductivity, abundant active sites, and hierarchical porosity of the TTCOF-Zn/NH 2 -CNTs nanocomposite, the modified electrode achieves an exceptional detection limit of 17 nM (linear range, 50 nM–1 mM) using differential pulse voltammetry, surpassing most reported sensors. The sensor also demonstrates excellent reproducibility, long-term stability, and strong anti-interference capability against common co-existing species. Its practical applicability was demonstrated through quantitative analysis of 4-NP in real lake water samples, with results validated by the HPLC method, underscoring the potential of D-A COF/CNT covalent hybrids for high-performance environmental monitoring. Graphic
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CELLULOSE
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2026
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IF 4.6
Chang Minmin,Peng Ke,Shen Peng,Jia Zhixin,Zhang Xuejin
Cellulose-based foams have received increasing attention in sustainable materials due to their biodegradability and environmental friendliness. However, the poor compressive resilience and insufficient structural stability caused by the dynamic hydrogen bond between cellulose molecular chains severely restrict their applications in flexible sensing. In this study, a synergistic strategy combining Fe 3 ⁺ cross-linking and fines reinforcement is successfully developed. Specifically, carboxymethyl cellulose (CMC) serves as the matrix, which is combined with fines to reinforce the network structure. Fines are fragmented microscale pulp fractions separated from beaten bleached softwood pulp after screening with a 200-mesh sieve. And carbon black (CB) is introduced to enhance the conductivity, while Fe 3 ⁺ is introduced for cross-linking to further strengthen the stability of materials, thus yielding the multifunctional CMC/fines/CB/Fe 3 ⁺ composite foams. The resulting foams possess excellent compressive resilience, with a height retention rate of 89.25% after 1000 cycles under 40% strain. Meanwhile, the foams also exhibit ultra-low density (0.0590 g/cm 3 ), high porosity (90.3%) and low thermal conductivity (0.049 W/(m·K)). Crucially, the CMC/fines/CB/Fe 3 ⁺ foams exhibit ultrahigh sensitivity (8.55 kPa⁻ 1 ), which can work stably in both air and underwater environments, and maintain sensing stability after water immersion-drying cycles. This study provides an effective strategy for the preparation of high-performance cellulose-based foams and lays a foundation for the development of waterproof wearable electronic devices.
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Nano-Micro Letters
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2026
·Vol. 18
·期 1
·417
·
IF 38.5
Lu Chunching,Zhang Guangxiang,Niu Yuxiang,Zhu Yupeng,Li Siyuan,Huo Hua,Ma Yulin,Zuo Pengjian,Yin Geping,Gao Yunzhi,Wang Liguang,Fu Chuankai,Chen Wei
Artificial solid electrolyte interphase offers a promising route to improve the lifespan and safety of quasi-solid-state sodium-metal batteries (QSMBs), yet its limited ion conductivity and the low liquidity of the polymer electrolyte often result in unstable Na plating/stripping kinetics and poor interfacial durability. Herein, we propose a surface-induced “top” Na deposition mechanism facilitated by an ultra-sodiophilic ionic/electronic mixed conductor interphase exhibiting strong Na + adsorption affinity, which ensures fast and dendrite-free Na anode operation. The embedded Na 3 Sb alloy phase, featuring high electronic conductivity and strong Na + adsorption energy, significantly accelerates interfacial ion diffusion and nucleation kinetics, forming a smooth and compact Na deposition layer that facilitates stable solid electrolyte interphase formation and preserves interfacial integrity. Consequently, Na||Na symmetric cells employing a 1, 3-dioxolane-based gel polymer electrolyte deliver an ultra-long-cycling lifespan of 1000 h at 0.5 mA cm −2 with a low overpotential of 40 mV. Moreover, QSMBs incorporating the modified Na anode and Na 3 V 2 (PO 4 ) 3 cathode demonstrate outstanding cycling stability (74.1% capacity retention after 9000 cycles at 2C) and superior rate capability (91.7 mAh g −1 at 5C). The work provides mechanistic insights and practical strategies for regulating Na deposition, paving the way toward high-performance QSMBs.
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PubMed
高影响因子
CELLULOSE
·
2026
·
IF 4.6
Li Zhen,Yang Jinqiu,Zeng Xiangdong,Xiong Zhengfeng,Li Jingjia,Su Xiuping,Li Yadong,Liu Feng
Passive radiative cooling technology offers a zero-carbon comfort solution for maintaining comfortable ambient temperatures. However, single-mode passive radiative cooling is significantly weakened by the shielding effect of high-humidity environments. Inspired by the thermoregulatory mechanisms of plant leaves, we designed a dendritic structure of amino-functionalized cellulose (ACE) for passive heat dissipation. ACE provides abundant amino groups and Schiff base sites, which not only enhance interactions with water molecules through hydrogen bonding but also facilitate solar radiation absorption via the stretching vibrations of the imine bonds (-C=N-). Leveraging these properties, an ACE@PVA dual-mode cooling film was fabricated using self-assembly technology. Despite its ultrathin profile (80 μm), the film achieves a hygroscopic capacity exceeding 3.32 ± 0.36 g/g and a solar reflectivity of 43.6 ± 2.1%. Under outdoor conditions, the film demonstrated excellent passive cooling performance, achieving subambient cooling of 4.7 °Cto 13.7 °Cduring daytime and 4.3 °Cat night. This ultrathin, dual-mode cooling film is well suited for dynamic seasonal and weather variations, achieving a theoretical cooling power of 142.9 W/m 2 , offering significant potential for mitigating the energy crisis and reducing greenhouse gas emissions.
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高影响因子
Advanced Fiber Materials
·
2026
·
IF 22.6
Ye Guomin,Chen Yi,Zhang Xinyang,Yang Nailiang,Wan Yanfen,Yang Peng
To overcome the limitations of conventional three-dimensional (3D) reconstruction methods in capturing detailed morphology and achieving rapid response, this study proposes a dimensionally hybridized zero-dimensional-one-dimensional (0D-1D) architecture inspired by Hertzian contact mechanics. Through finite element analysis, we identified that the 0D-1D contact mode achieves an optimal balance between stress concentration and distribution, with a moderate peak stress of 246.7 Pa, in contrast to the high-but-localized stress in 1D-1D and the overly dissipated stress in 0D-0D contacts. Guided by this insight, 0D Polyvinylidene fluoride (PVDF) microspheres are strategically deposited via electrospray onto both sides of an electrospun 1D PVDF nanofiber network. This hierarchical structure promotes efficient stress transfer, enhances dipole alignment, and improves charge generation efficiency, resulting in a 122.6% increase in pressure sensitivity, a broad sensing range (3-510 kPa), and exceptional cyclic stability, which retained 96.6% after 10000 cycles. Integrated with an artificial neural network, the sensor achieves 90.5% accuracy in classifying sliding trajectories, 99.3% accuracy in real-time 3D contour recognition, and 100% accuracy in 3D contour reconstruction. These results underscore its strong potential for advanced applications in intelligent robotics, wearable electronics, and human-machine interfaces. Graphical
The alternative text for this image may have been generated using AI.
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高影响因子
CHINESE JOURNAL OF POLYMER SCIENCE
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2026
·
IF 4.6
He Jie,Hu Chang-Ning,Yang Zhou-Ya,Yang Hui,Peng Yin-Jie
Conductive hydrogels, with their excellent flexibility and tunable electrical conductivity, have shown broad application prospects in emerging fields such as flexible strain sensors and triboelectric nanogenerators (TENG). In this study, a conductive sodium carboxymethyl cellulose (CMC)/ polypyrrole (PPy)/polyacrylamide (PAM)(CPA) hydrogel was developed by integrating a CMC/PPy composite, synthesized via in situ polymerization, into a hydrophobic-associated polyacrylamide network. This hydrogel exhibits excellent mechanical properties, with a tensile strain as high as 1735%, demonstrating extremely high ductility and deformation capacity. The flexible sensor based on CPA hydrogel has a wide detection range (0%–500%) and can monitor the movements of various parts of the human body. In addition, the TENG assembled based on CPA hydrogel achieves stable electrical output performance, enabling it to power small wearable electronic devices and promote self-powered signal transmission, showing broad application prospects in the fields of intelligent human-machine interaction and wearable electronics. The alternative text for this image may have been generated using AI.
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MICROCHIMICA ACTA
·
2026
·Vol. 193
·期 7
·458
·
IF 5.4
Zhou Yaqiu,Zhu Linlian,Li Mengwei,Yao Yi,Su Mengjie,Wu Zengqiang,Yu Chunmei
A flexible electrochemical sensing platform on the basis of carbon cloth modified with zeolite imidazole framework-67/carbon nanotubes nanocomposite with catalase-like activity was developed for in situ and real-time tracking of H 2 O 2 produced by living cells. The obtained sensor exhibits excellent electrochemical performance for detecting H 2 O 2 with a broad linear response range from 1 µM to 5.2 mM and a detection limit of 0.3 µM. Owing to the favorable biocompatibility and mechanical stability of the prepared electrodes, living cells can be proliferated well on their surfaces, thereby achieving in situ and real-time profiling of endogenous H 2 O 2 flux from normal and cancer cells. This work proposed a novel sensing platform for extracellular analysis, providing an innovative tool for the dynamic monitoring of biomarkers generated by cellular metabolism in cell biology. Graphical abstract The alternative text for this image may have been generated using AI.
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PubMed
高影响因子
Journal of Coatings Technology and Research
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2026
·
IF 3.4
Bao Qiuru,Xu Wen-Cong,Tian Yuyu,Zhang Kai,Wu Juying
In recent years, the development of intumescent fire-retardant coatings (IFRCs) has emerged as a critical strategy for enhancing fire safety in steel structures. However, traditional IFRCs exhibit limitations in meeting the demands of environmental protection, high-efficient fire resistance, and smoke suppression in construction applications. In this study, an organic-inorganic hybrid nanoflame retardant (HP@ZIF) was designed and synergistically applied with ammonium polyphosphate/triazine charring agent (APP/CFA) into an epoxy resin (EP) matrix, fabricating a high-performance IFRC. Back-surface temperature testing results suggested that HP@ZIF enhanced the thermal insulation of IFRC, which was also reflected in a significant increase in the char expansion ratio. The 20-min backside temperatures of the steel plate decreased from 576°C (uncoated steel) to 187°C (S3 coating), with the heat insulation efficiency of 67.5%, showing excellent fire retardant and thermal insulation performance of this EP coating. Additionally, total heat release (THR), total smoke release (TSR), and fire growth rate (FIGRA) of IFRC in the cone calorimeter test (CCT) were reduced by 70.1%, 72.0%, and 90.2%, respectively, demonstrating superior flame retardant and smoke suppression properties. Scanning electron microscopy (SEM) and Raman spectroscopy revealed that a dense, continuous char layer was formed after combustion, with enhanced mechanical integrity and thermal barrier functionality. More importantly, this EP coating maintained superior fire resistance after 7 d of water immersion. This study provides an economical and efficient solution for enhancing fire protection in modern buildings.
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危险品化学品经营许可证（带存储）