MOLECULAR CELL
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2026
·
IF 16
Ru-Feng Song,Lin Li,Xin-Ru Guo,Cai-Yi Liao,Wen-Cheng Liu
H 2 O 2 functions as a signaling molecule regulating plant growth, development, and stress responses; however, its role in jasmonic acid (JA) signaling transduction and JA-regulated biological processes remains elusive. Here, we report that General regulatory factor 8 (GRF8) is a critical factor inhibiting JA signaling, while H 2 O 2 removes this inhibition to facilitate the JA response during root growth and leaf senescence in Arabidopsis . GRF8 interacts with and inhibits MYC2, the key transcription factor in JA signaling. It recruits Jasmonate-ZIM domain (JAZ) repressors to enhance their interaction with and inhibition of MYC2. Additionally, GRF8 competes with Mediator 25 (MED25), a subunit of the Mediator coactivator complex, to interact with MYC2. Upon increased JA levels, H 2 O 2 sulfenylates GRF8 at cysteine-103, reducing its interaction with MYC2 and thereby releasing MYC2 activity to stimulate the JA response. Together, our findings suggest that H 2 O 2 -mediated sulfenylation of GRF8 provides a redox-based mechanism to modulate JA signaling in Arabidopsis .
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PubMed
高影响因子
Nature Communications
·
2026
·
IF 18.1
Meng Genping,Wei Shuai,Li Ning,Yin Yuhui,Dong Bin,Sun Shihao,Hu Guowen,Wang Hao,Wang Baodui
Lead halide perovskites are promising for artificial photosynthesis but suffer from aqueous instability. Here, we stabilize CsPbI 3 quantum dots within a hydrophobic chlorine-functionalized covalent organic framework through multisite atomic-chlorine passivation, forms dual Cl-Pb coordination and Cl-I halogen bonding at the interface. This suppresses ionic migration while creating a gas-solid-liquid triphase interface for enhanced O 2 diffusion. The resulting S-scheme heterojunction spatially separates carriers to concurrently drive two-electron oxygen reduction and water oxidation for H 2 O 2 synthesis without sacrificial agents. The system achieves production rates of 20.37 mmol h −1 g −1 in seawater, with a solar-to-chemical conversion efficiency of 1.38%, and operates stably for 20 h. Importantly, natural sunlight tests yield 11.7 mmol L −1 H 2 O 2 in 10 h. Mechanistic studies confirm synergistic interfacial charge transfer and dual-reaction pathways via both oxygen reduction and water oxidation. This work demonstrates an approach for robust perovskite-based photocatalysts toward solar-driven chemical synthesis from seawater.
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高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2018
·
IF 6.735
Yuwei Pan,Minghua Zhou,Jingju Cai,Xiang Li,Wei Wang,Bing Li,Xuejie Sheng,Zhuoxuan Tang
Nowadays, Fenton (Fe 2+ /H 2 O 2 ) process is increasingly applied to wastewater treatment, however, the treatment efficiency would be inhibited largely when treated salty wastewater. To overcome this limitation, pre-magnetization (pre-magn-Fe 0 )/H 2 O 2 process was investigated to treat salty wastewater, which could enhance the degradation rate of organic pollutants (1.2–171.2 folds enhancement) and reduce reagents dosage (save 75% H 2 O 2 ) in salty system compared with Fe 0 /H 2 O 2 process, using Orange G as the target pollutant and Na 2 SO 4 as the model salty system. The characterizations by SEM, XRD and XPS and the intensity of DMPO–OH adduct signals in different processes confirmed this enhancement attributed to the increase of corrosion of Fe 0 inducing fast catalysis of H 2 O 2 and generation of hydroxyl radicals. Pre-magn-Fe 0 /H 2 O 2 process could also have 5.9, 26.4 and 93.7 folds enhancement in NaCl, NaNO 3 and Na 2 HPO 4 salty system, respectively. Meanwhile, pre-magn-Fe 0 /H 2 O 2 process could keep close performance in Na 2 SO 4 and NaCl salty systems and have better performance in NaNO 3 and Na 2 HPO 4 salty systems than Fenton process. Pre-magn-Fe 0 /H 2 O 2 process also had remarkable improvement (1.1–5.3 folds) on the removal of many refractory contaminants in salty system. Furthermore, it could also keep good performance in real reverse osmosis concentrated wastewater and petrochemical wastewater. Therefore, pre-magn-Fe 0 /H 2 O 2 process is a more cost-effective process to treat salty wastewater, which could have not only improved performance than conventional system and Fe 0 /H 2 O 2 process, but also good performance as Fenton process.
研究领域:
环境工程
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化学工程
·
水处理技术
·
高级氧化技术
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DOI
高影响因子
Theranostics
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2021
·
IF 11.556
Nana Wang,Qin Zeng,Ruijing Zhang,Da Xing,Tao Zhang
Activatable theranostics, integrating high diagnostic accuracy and significant therapeutic effect, holds great potential for personalized cancer treatments; however, their chemodynamic modality is rarely exploited. Herein, we report a new in situ activatable chemodynamic theranostics PAsc/Fe@Cy7QB to specifically recognize and eradicate cancer cells with H 2 O 2 -catalyzed hydroxyl radical (•OH) burst cascade. Methods: The nanomicelles PAsc/Fe@Cy7QB were constructed by self-assembly of acid-responsive copolymers incorporating ascorbates and acid-sensitive Schiff base-Fe 2+ complexes as well as H 2 O 2 -responsive adjuvant Cy7QB. Results: Upon systematic delivery of PAsc/Fe@Cy7QB into cancer cells, the acidic microenvironment triggered disassembly of the nanomicelles. The released Fe 2+ catalyzed the oxidation of ascorbate monoanion (AscH - ) to efficiently produce H 2 O 2 . The released H 2 O 2 , together with the endogenous H 2 O 2 , could be converted into highly active •OH via the Fenton reaction, resulting in enhanced Fe-mediated T 1 magnetic resonance imaging (MRI). The synchronously released Cy7QB was activated by H 2 O 2 to produce a glutathione (GSH)-scavenger quinone methide to boost the •OH yield and recover the Cy7 dye for fluorescence and photoacoustic imaging. Conclusion: The biodegradable PAsc/Fe@Cy7QB designed for tumor-selective multimodal imaging and high therapeutic effect provides an exemplary paradigm for precise chemodynamic theranostic.
研究领域:
癌症治疗
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纳米医学
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医学影像
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生物医学工程
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DOI
PubMed
高影响因子
INTERNATIONAL JOURNAL OF HYDROGEN ENERGY
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2021
·
IF 5.816
Chunyu Zhang,Guozhu Liu,Bo Ning,Shuairen Qian,Danning Zheng,Li Wang
The electrochemical oxygen reduction reaction (ORR) via two-electron pathway is a sustainable way of producing hydrogen peroxide. Nanostructured carbon materials are proved to be effective catalysts for 2e − ORR. Herein, a series of mesoporous carbon with tunable nitrogen species and oxygen functional groups were synthesized by varying the added amount of dopamine hydrochloride as nitrogen and oxygen source. The modified catalysts exhibited higher content of pyrrolic-N and ether C–O groups which are confirmed by a series of characterization. Raman spectra and correlation analysis revealed that the increased proportion of defect sites in carbon materials are closely related to the introduced pyrrolic-N and ether C–O groups. And the rotating ring-disk electrode (RRDE) measurement carried out in 0.1 M KOH electrolyte showed the H 2 O 2 selectivity increased with the content of defect sites. Among them, the optimized catalyst (NOC-6M) exhibited a selectivity of 95.2% and a potential of 0.71 V vs. RHE at −1 mA cm −2 . Moreover, NOC-6M possessed the high H 2 O 2 production rate of 548.8 mmol g cat −1 h −1 with faradaic efficiency of 92.4% in a two-chamber H-cell. Further mechanistic analysis revealed that the introduction of pyrrolic-N and ether C–O are likely to improve the binding energy of the defect sites toward ∗OOH intermediate, resulting in a more favorable 2e − ORR pathway for H 2 O 2 production.
研究领域:
材料科学
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电化学
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高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
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2020
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IF 5.774
Min Lei,Qian Gao,Kemeng Zhou,Parikshit Gogoi,Jing Liu,Jiabao Wang,Hainong Song,Shuangfei Wang,Xinliang Liu
Adsorbable organic halogens (AOX) are used as a parameter to determine the total amount of organic halogens in the environment. 4-chlorophenol (4-CP), as a type of AOX, can persist in the environment for a long time and is not biodegradable. 4-CP has significant carcinogenic and teratogenic effects on humans and animals. In this study, a catalytic system employing phosphomolybdic acid (PMA) and hydrogen peroxide (H 2 O 2 ) was developed for degrading 4-CP. The degradation and the mechanisms of 4-chlorophenol (4-CP) as an AOX simulant was investigated. The removal efficiency of 4-CP, the AOX content, and total organic carbon were used to evaluate its molecular structure. The results show that 4-CP was fully converted, 19.81% to other species of AOX and 44.52% to CO 2 and H 2 O. Moreover, the intermediates were detected and analyzed, and the possible pathways of 4-CP degradation were drawn. 4-CP attached to PMA, there by leading to ring-opening or dichlorination, and the generation of some other chemical species, such as phenol , benzoquinone, cyclohexanone, 4-chlorohexa-2,4-dien-1-ol, and 3-chlorohexa-2,4-diene-1,6-diol. These species would then be mineralized under the effects of free radicals. PMA can promote the formation of free radicals and shows exceptional efficiency in the degradation of 4-CP.
研究领域:
环境化学
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催化
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水处理
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污染物降解
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高影响因子
Journal of Materials Chemistry A
·
2021
·Vol. 9
·期 29
·15948-15954
·
IF 12.732
Yani Ding,Wei Zhou,Liang Xie,Shuai Chen,Jihui Gao,Fei Sun,Guangbo Zhao,Yukun Qin
Hydrogen peroxide (H2O2) electrosynthesis through 2-electron oxygen reduction reaction (ORR) is an attractive alternative to the industrial anthraquinone oxidation method. Conventional H2O2 electrosynthesis processes usually operate under galvanostatic or potentiostatic conditions that occasionally result in unsatisfactory selectivity and efficiency. Herein, we applied pulsed electrocatalysis to achieve synergy between reactant adsorption, electrochemical reaction, and product diffusion by regulating the pulsed potential, pulsed width, and duty cycle, which could increase H2O2 production by 138.12%. For the first time, we revealed that pulsed electrocatalysis could regulate the adsorption of ORR intermediates by affecting the charge and discharge process of the electric double layer (EDL) based on density functional theory (DFT) calculations. Finally, we provided a new perspective on the mechanism of pulsed electrocatalysis to promote the production of H2O2via 2-electron ORR, thereby offering guidance for the precise control and efficient conduction of electrochemical reactions in the future.
研究领域:
电化学
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催化
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化工工程
·
材料科学
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DOI
高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
·
2020
·
IF 5.774
Yuwei Pan,Zhuoyu Bu,Cunxing Sang,Hongjin Guo,Minghua Zhou,Ying Zhang,Yusi Tian,Jingju Cai,Wei Wang
Ethylenediaminetetraacetic acid (EDTA) was used to enhance pre-magnetized Fe 0 /H 2 O 2 process for sulfamethazine (SMT) removal at neutral pH. Only 19.4% SMT was removed in pre-Fe 0 /H 2 O 2 within 60 min at neutral pH while 90.6% SMT was removed after addition of 0.1 mM EDTA. Meanwhile, k (10 3 ) value for SMT removal in pre-Fe 0 -EDTA/H 2 O 2 was 1.3 folds larger than in Fe 0 -EDTA/H 2 O 2 . Single-factor experiments and response surface methodology (RSM) were used to optimize the system for SMT removal. Maximum k (10 3 ) value was 81.4 min −1 obtainning at conditions of Fe 0 0.28 g L −1 , EDTA 0.13 mM, and H 2 O 2 36.2 μM. The presence of EDTA and magnetization could inhibit the generation of iron oxides , reduce the contact angle of Fe 0 , and improve the recovery of surface Fe II which induced a faster catalytic decomposition of H 2 O 2 . The system could still achieve good performance for removing SMT after six consecutive reaction cycles. These results demonstrated that pre-Fe 0 -EDTA/H 2 O 2 system has the potential application for wastewater treatment .
研究领域:
环境科学
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化学工程
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高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2018
·
IF 6.735
Mantang Chen,Zhimin Zhang,Lihua Zhu,Nan Wang,Heqing Tang
The present work aimed at using bisulfites (HSO 3 − ) to enhance the oxidative degradation of bisphenol A (BPA) in a Fenton process based on the Fe 3+ -H 2 O 2 reagents. It was confirmed that both the degradation and mineralization of BPA were drastically enhanced by the addition of HSO 3 − . Typically, the use of 0.1 mmol L −1 Fe 3+ , 0.3 mmol L −1 HSO 3 − and 10 mmol L −1 H 2 O 2 achieved a complete degradation of BPA (0.05 mmol L −1 ) in only 2 min. The addition of HSO 3 − increased the BPA degradation rate constant from 0.045 min −1 in the Fe 3+ -H 2 O 2 system to 2.71 min −1 in the Fe 3+ -HSO 3 − -H 2 O 2 system by 60 times. This drastic enhancement effect of HSO 3 − was attributed to its complexing and reducing abilities. The formation of FeSO 3 + complex prevented the precipitation of Fe 3+ and accelerated the cycling of Fe 3+ /Fe 2+ ; the reducing ability of HSO 3 − further favored the transformation of Fe 3+ to Fe 2+ . Several reactive species, including OH, SO 3 − and SO 4 − were responsible for the degradation of BPA, among which OH was the dominant one. The proposed Fe 3+ -HSO 3 − -H 2 O 2 system is suggested be able to act as the followed stage of a traditional Fe 2+ -H 2 O 2 system in the engineering setting.
研究领域:
环境科学
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化学工程
·
污染控制
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高影响因子
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
·
2023
·
IF 6.8
Wei Liu,Jin Zhang,Qun Kang,Hongbing Chen,Ru Feng
Environmental pollution by organic pollutants poses a great threat to the ecosystem and human development. Solar-powered catalytic oxidation technology can solve the existing energy and pollution crisis. Hence, in this work, cubic nano-In 2 O 3 modified g-C 3 N 4 composite was synthesized by in situ calcination, then it was coupled with hydrogen peroxide for the degradation of antibiotic under visible light. The results of SEM and XPS showed that In 2 O 3 and g-C 3 N 4 were closely combined. The catalytic oxidation efficiency of the antibiotic doxycycline was greatly improved when the as-prepared compound was coupled with hydrogen peroxide, and 88.2% of doxycycline was degraded within 80 min. By designing the active species inhibition test, it was found that a large number of hydroxyl radicals were generated in the system after adding hydrogen peroxide, which accelerated the degradation of the target. Hydrogen peroxide not only acts as a source of hydroxyl radical, but also as an active electron acceptor, which promotes the separation of photogenerated electron-hole pairs in the composite photocatalyst. Therefore, the double oxidation system formed by In 2 O 3 /g-C 3 N 4 coupled with hydrogen peroxide can degrade the target at a higher rate. This work provided a research basis for the synthesis of In 2 O 3 with regular morphology and simplified synthesis of In 2 O 3 /g-C 3 N 4 , and explored the practicability of the coupling method of double advanced oxidation for pollutant degradation.
研究领域:
环境科学
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材料科学
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PubMed
高影响因子
Journal of Environmental Chemical Engineering
·
2022
·
IF 7.968
Xiaolin Han,Nannan Wang,Wei Zhang,Xiaodong Liu,Qi Yu,Juying Lei,Lei Zhou,Guangli Xiu
In this work, the presence of ascorbic acid (AsA) in MIL-88B(Fe) / H 2 O 2 system was demonstrated to significantly increase the sulfamethoxazole (SMX) degradation efficiency. The SMX degradation rate in AsA/MIL-88B(Fe) / H 2 O 2 system was 0.177 L/(mg∙min), which was 60 times that of the MIL-88B(Fe) / H 2 O 2 system. Moreover, the study shows that AsA not only promotes SMX degradation in Fenton-like systems but also expands its pH application range. The effect of coexisting anions on the catalytic performance of the AsA/MIL-88B(Fe) / H 2 O 2 system was also investigated. Then, reactive species were detected via quenching experiments, which indicated •OH as the dominant free radical contributing to SMX degradation. Meanwhile, ESR determinations confirmed the existence of •OH and O2 − • in AsA/MIL-88B(Fe) / H 2 O 2 system. The high activity of the AsA/MIL-88B(Fe) / H 2 O 2 system was attributed to the effective surface Fe(III)/Fe(II) cycle promoted by AsA, and a possible mechanism of the AsA/MIL-88B(Fe) / H 2 O 2 system is proposed. The possible pathways for SMX and AsA degradation in the AsA/MIL-88B(Fe) / H 2 O 2 system are proposed based on the identified intermediates and the ecotoxicity analysis was conducted by ECOSAR . Finally, experimental results using the actual surface water and groundwater revealed the excellent availability of AsA/MIL-88B(Fe)/H 2 O 2 system in remediating SMX contaminated water . This study presents a novel, efficient Fenton-like system using AsA and iron-based metal-organic frameworks for sulfonamide removal from water.
研究领域:
环境科学
·
化学
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高影响因子
CHEMICAL RESEARCH IN CHINESE UNIVERSITIES
·
2018
·Vol. 34
·期 2
·260-268
·
IF 1.248
Ren Hejun,Ma Taigang,Zhao Jian,Zhou Rui
A simple and efficient colorimetric biosensing for hydrogen peroxide and glucose with peroxidase-like vitamin C(V c ) functionalized Fe 3 O 4 magnetic nanoparticles(V c Fe 3 O 4 MNPs) as a catalyst is reported. Compared with Fe 3 O 4 MNPs and other catalysts, V c Fe 3 O 4 MNPs exhibited superior catalytic properties. Kinetic studies indicated that vitamin C incorporated on Fe 3 O 4 MNPs improved the affinity toward H 2 O 2 . As low as 0.29 μmol/L H 2 O 2 can be detected with a wide linear range of 0.5―100 μmol/L H 2 O 2 ; moreover, as low as 0.288 μmol/L glucose can be detected with a linear range of 0.5―25 μmol/L glucose. The detection method was highly sensitive in sensing H 2 O 2 and glucose. The robustness of V c Fe 3 O 4 MNPs rendered them suitable for wide ranging applications.
研究领域:
生物化学
·
纳米医学
·
分析化学
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DOI
高影响因子
危险品化学品经营许可证（带存储）