DALTON TRANSACTIONS
·
2024
·
IF 3.5
Hang Liu,Haozhou Tian,Chunhui Sun,Qiang Wang,Hongqun Zhu,Xuezhong Yang,Haoran Wang,Yuhong Zhang
A series of Nd3+/Yb3+ co-doped Ca2LaTaO6 (CLTO) phosphors are synthesized by a high temperature solid phase method. Structural characterization confirms the successful incorporation of Nd3+ and Yb3+ ions into the CLTO host lattice. The photoluminescence excitation (PLE) spectra and photoluminescence (PL) spectra of CLTO:Nd3+ and CLTO:Nd3+/Yb3+ are investigated in detail. Under the excitation of ultraviolet (UV) and visible (VIS) light, the CLTO:Nd3+/Yb3+ phosphor emits broadband near infrared (NIR) luminescence. In particular, the luminescence intensity of the Yb3+ ion is increased through an energy transfer (ET) process from Nd3+ to Yb3+. The luminescence mechanism of the CLTO:Nd3+/Yb3+ sample is analyzed based on the decay lifetime and PL spectra. In addition, the NIR emission intensity of Yb3+ ions is also enhanced by doping K+ ions. The broadband luminescence (850–1050 nm) of the CLTO:Nd3+/Yb3+/K+ phosphor has good application in solar cells and anti-counterfeiting.
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DOI
PubMed
高影响因子
Bioanalysis
·
2024
·
IF 1.9
Xiemin Qi,Ning Chen,Qinxin Song,Yanan Chu,Haiping Wu,Jingwen Shan,Huijie Yue,Guohua Zhou
Aim: Differences are existed in the bioactivity among various vitamin K (VK) forms. To investigate the correlation between clinical parameters of initial anticoagulation and plasma levels of VK1 and VK2 (MK-4 and MK-7), it was necessary to establish a quantitative method for simultaneous determination.Materials & methods: Plasma samples in cardiovascular patients were extracted by cyclohexane and analyzed using a C18 column. Baseline concentrations of VK1, MK-4 and MK-7 were 0.98 ± 0.52 ng/ml, 0.45 ± 0.13 ng/ml and 0.65 ± 0.31 ng/ml, respectively. The concentrations of MK-7 and total VKs were significantly relevant to INR0, respectively (p = 0.010 and p = 0.048, respectively).Conclusion: Thus, when adjusting anticoagulation dosage, concentrations of various VK homologues might be considered.
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DOI
PubMed
高影响因子
PHYTOMEDICINE
·
2025
·
IF 8.3
Xueling Hu,Chunxia Liu,Ziling Tang,Mingyu Pan,Ailing Fang,Ling Li,Xiangbo Meng,Xiyang Tang,Yanzhi Liu,Xinluan Wang,Hao Gao,Jian Zou,Zuocheng Qiu
Background Cathepsin K (CTSK) is a key enzyme in bone resorption, making it a promising target for osteoporosis treatment. Active-site inhibitors of CTSK are effective but have undesirable side effects, while ectosteric inhibitors may provide a safer alternative. Purpose This study investigates whether Sophoraflavanone G (SG), derived from Rhizoma Drynariae , can act as an ectosteric CTSK inhibitor to attenuate osteoporotic bone loss and explores its underlying mechanisms. Study Design SG's effects were evaluated in an ovariectomized (OVX) osteoporotic mice model, with in vitro experiments assessing SG's interaction and binding affinity with CTSK. Methods Micro-CT, histology, and mechanical testing were used to evaluate bone density and strength. CTSK activity and expression were assessed by immunohistochemistry and western blotting. Cell thermal shift assays, isothermal titration calorimetry, CTSK site-specific degradation assays, molecular docking and dynamic simulation were performed to study SG's binding affinity and inhibitory effects. Biosafety, including body weight, uterine histomorphometry, and toxicity of the heart and lung, was also assessed. Results SG improved bone mineral density, microarchitecture, and strength, primarily by inhibiting bone resorption. It inhibited CTSK's enzymatic activity with a strong binding affinity (KD: 8.49 μM) and effectively inhibited osteoclast function. CTSK site-specific assays showed SG inhibited CTSK-mediated degradation of type I collagen. Unlike odanacatib, SG did not affect gelatin or TGF-β1 degradation in fibroblasts. Biosafety assessments revealed no adverse effects. Conclusion SG acts as an ectosteric CTSK inhibitor, offering a safer alternative for postmenopausal osteoporosis treatment by selectively inhibiting bone resorption without the side effects associated with active-site inhibitors.
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JOURNAL OF CHEMICAL AND ENGINEERING DATA
·
2025
·
IF 2.1
Cunzhi Zhao,Chuang Xie
The solubility of herbicide topramezone (TOP) in 16 pure solvents (methanol, ethanol, n-propanol, isopropanol, n-butanol, isobutanol, methyl acetate, ethyl acetate, n-propyl acetate, isopropyl acetate, n-butyl acetate, acetone, acetonitrile, acetonitrile, tetrahydrofuran, and toluene) was measured by the gravimetric method over temperatures ranging from 283.15 to 323.15 K at 0.1 MPa. With an increase in temperature, the solubility of TOP also increased in all solvents. Isopropanol exhibited the lowest solubility at 283.15 K, whereas tetrahydrofuran showed the highest solubility at 323.15 K. The solvent effects, including polarity, hydrogen bond donor propensity, hydrogen bond acceptor propensity, and cohesive energy density, were used to analyze the solubility of TOP in various solvents. For the effect of solvent type on solubility, hydrogen bond donation is dominant in alcoholic solvents, whereas hydrogen bond acceptors are dominant in nonalcoholic solvents. The experimental solubility data were correlated with four models, namely, the modified Apelblat equation, λh equation, van’t Hoff equation, and NRTL equation, with a relative deviation of less than 5%. Furthermore, mixing thermodynamic properties of TOP in selected solvents were calculated by the NRTL model, which showed that the mixing process was spontaneous and entropy driven.
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ACS Sustainable Chemistry & Engineering
·
2025
·
IF 7.3
Ya Chu,Weiqiang Zhang,Baoye Hu,Jinghong Wen,Mengmei Qin,Guangjiu Zhao
Regulation of surface ligands in hybrid organic–inorganic perovskite quantum dots (HOIP QDs) is key to enhancing their optoelectronic properties. However, achieving both high photoluminescence (PL) and long-term stability in chiral HOIP QDs remains challenging. Here, we report the use of chiral anthraquinone derivatives (AQ) as surface ligands, replacing conventional long-chain alkyl ligands, to construct two potassium-doped chiral QDs, (R)AQ-QDs and (S)AQ-QDs. These QDs exhibit high photoluminescence quantum yields (PLQYs) of 98.74 and 97.68%, respectively, along with notable stability. Optical characterization indicates an efficient chirality transfer from the organic ligands to the K0.23MA0.77PbBr3 lattice. Furthermore, density functional theory (DFT) calculations and femtosecond transient absorption (fs-TA) spectroscopy reveal reduced surface trap states, as evidenced by stronger ligand binding and prolonged carrier lifetimes. A white-light-emitting diode (LED) fabricated using the AQ-QDs shows a color rendering index (CRI) of 65.1 and a correlated color temperature (CCT) of 6169 K. The reported work highlights the potential of chiral ligand engineering in improving PL efficiency and stability in perovskite QDs.
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Nature Communications
·
2025
·Vol. 16
·期 1
·9977
·
IF 15.7
Qin Feiyu,Bai Xiaoya,Fang Yue-Wen,Zhu Pengli,Wang Jun,Cheng Pengtao,Wang Dunhui,Hu Lei,Sun Jun,Ding Xiangdong
Giant negative thermal expansion (NTE), defined by volumetric expansion α V
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CERAMICS INTERNATIONAL
·
2025
·
IF 5.6
Lanxuan Yang,Lianjiang Tan,Ruili Xu,Zeyuan Tian,Tian Tian,Zhifu Liu,Lili Liu,Yaoqing Chu
The local crystal-field symmetry within a host material plays a critical role in modulating the luminescence behavior of Sm 3+ ions. In this study, we propose a novel Si 4+ doping strategy to enhance the photoluminescence properties of Sm 3+ in a Sr 3 Ga 2 Ge 4 O 14 host, with the effects proposed to be associated with alterations in the symmetry of the local coordination environment. A series of Si 4+ /Sm 3+ co-doped phosphors was synthesized via solid-state reaction. At an optimal Si 4+ doping level of 50 mol%, the emission intensity of Sm 3+ increased by approximately 40%. Further introduction of K + as a charge compensator considerably improved the internal quantum efficiency from 25.12% to 47.28% and color purity from 96.8% to 99.9%. A prototype WLED using the optimized phosphor exhibited a low CCT (5769 K) and a high CRI ( R a = 87.6), satisfying the requirements for indoor lighting. The phosphor was also incorporated into a PVA-based anti-counterfeiting ink, showing bright, stable, and substrate-independent UV-excited fluorescence. This work provides a feasible doping strategy for developing high-performance orange-red phosphors and demonstrates their potential in high-quality WLED and advanced anti-counterfeiting applications.
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JOURNAL OF CHEMICAL AND ENGINEERING DATA
·
2021
·
IF 2.694
Yan Shi,Shui Wang,Jidong Wang,Tingting Liu,Yixin Qu
In this work, the solubility of amitriptyline hydrochloride (AMT) in 13 monosolvents was experimentally measured in the temperatures ranging from 283.15 to 323.15 K under atmospheric pressure with the aid of laser dynamic solubility monitor devices. The solubility as a function of temperature in different monosolvents was regressed using two activity coefficient models (Wilson and nonrandom two liquid (NRTL)) and three semiempirical equations (modified Apelblat, three-parameter Van’t Hoff, and λh), Based on the solubility data and the regression parameters of the Wilson model, the mixing thermodynamic properties (mixing Gibbs energy, mixing enthalpy, mixing entropy) as well as the activity coefficient and the reduced excess enthalpy at infinitesimal concentration were evaluated.
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JOURNAL OF CHEMICAL AND ENGINEERING DATA
·
2020
·
IF 2.369
Ying Zhang,Taotao Zhan,Junshuai Chen,Xin Li,Qi Zhou,Maogang He
The experimental speeds of sound for the binary system of ethanol (1) + n-heptane (2) with the mole fractions of ethanol being (0.100, 0.300, 0.500, 0.700, and 0.900) were measured by Rayleigh-Brillouin light scattering spectroscopy at temperatures from 293.35 to 433.89 K along three isobaric lines from 0.1 to 5.0 MPa. The expanded relative uncertainty for the reported speed of sound is estimated to be 1.6% with the level of confidence of 0.95 (coverage factor k = 2). The experimental data were correlated as a function of temperature and pressure, yielding absolute average percentage deviations of 0.34, 0.20, 0.38, 0.28, and 0.29% for the mole fractions of ethanol being 0.100, 0.300, 0.500, 0.700, and 0.900, respectively. Within the temperature limits of 298.15–318.15 K, the derived thermo-acoustic properties for the binary system of ethanol (1) + n-heptane (2), including the density, the specific isobaric heat capacity, the isentropic compressibility, the isobaric thermal expansivity, the isothermal compressibility, the specific heat ratio, the internal pressure and the free volume at pressures up to 5.0 MPa, and the intermolecular free length under atmospheric pressure were calculated and analyzed.
研究领域:
物理化学
·
热力学
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FLUID PHASE EQUILIBRIA
·
2014
·
IF 2.241
Xuehong Zhao,Shu’ni Li,Quanguo Zhai,Yucheng Jiang,Mancheng Hu
This article deals with the mean activity coefficients of LiCl in amide–water mixtures with both ɛ -increasing co-solvent (urea–water, N -methylformamide–water), and ɛ -decreasing co-solvent ( N , N -dimethylformamide–water, N , N -dimethylacetamide–water) systems at 298.15 K by potentiometric method. Meanwhile, thermodynamic properties including the osmotic coefficients, the excess Gibbs free energy, the standard solubility product, the primary LiCl hydration number and the standard free energy of transference from water to the mixtures were also calculated. The nonideal behavior of these systems has been discussed in terms of the Pitzer, the Modified Pitzer and the extended Debye–Hückel equations parameters.
研究领域:
物理化学
·
溶液化学
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高影响因子
APPLIED PHYSICS LETTERS
·
2022
·Vol. 121
·期 20
·
IF 3.971
Guan Xiaoli,Li Hongjiang,Yu Zhiyuan,Yu Xiaohan,Jin Shuaizhao,Gu Xin,Liu Xiang
A series of La 0.7 K 0.3− x Sr x MnO 3 (0.00 ≤ x ≤ 0.3) films were fabricated on LaAlO 3 substrates using a sol-gel spin-coating technique. The relationship between electrical transport properties and a microstructure was explained via the Jahn–Teller effect, a phenomenological percolation model, and a double-exchange mechanism. The results revealed the strong impact of K and Sr co-occupying A-sites on the formation of Mn 3+ /Mn 4+ pairs, crystal structure, conductivity, surface morphology, and in-plane and out-of-plane strains. The as-fabricated La 0.7 K 0.25 Sr 0.05 MnO 3 films showed a peak temperature coefficient of resistivity of 16.63% K −1 at 298.3 K.
研究领域:
材料科学
·
凝聚态物理
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JOURNAL OF SOLUTION CHEMISTRY
·
2017
·Vol. 46
·期 9
·1767-1777
·
IF 1.342
Guo Lijiang,Wang Yaxiao,Tu Lanying,Li Jianqiang
Water activities for the MgCl 2 –RbCl–H 2 O ternary system and its sub-binary MgCl 2 –H 2 O and RbCl–H 2 O systems at 298.15 K have been measured using the isopiestic method. The measured results for the binary systems agree well with literature data. The measured equal water activity lines for the MgCl 2 –RbCl–H 2 O ternary system deviate from Zdanovskii’s rule. The solubilities for the MgCl 2 –RbCl–H 2 O ternary system also have been measured using a isothermal visual first/last crystal method, and the results are consistent with one reported set of solubility data. Pitzer’s model was selected to correlate the measured water activity and solubility data and the parameters reported in the literature are re-examined by comparing the model-calculated equal water activity lines and solubilities with experimental values measured in this work. New and reasonable parameters are obtained by fitting the water activity and solubility data measured in this work and those reported in the literature. The water activities and solubilities were simulated with the new parameters and the results show that the Pitzer model can successfully represent the thermodynamic properties and be used to calculate the solubility isotherms.
研究领域:
化学热力学
·
物理化学
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