CHEMICAL ENGINEERING JOURNAL
·
2018
·
IF 6.735
Xuelian Huang,Dongxu Zhou,Yilin Wang,Chao He,Weifeng Zhao,Shudong Sun,Changsheng Zhao
In the present study, we firstly reported a green approach to prepare synthetic polymer-based particle adsorbents in aqueous solution. A novel spherical hydrogel capsule (SHC) was prepared through a facile method by partial ionic-crosslinking of carboxylated chitosan (CCS). Then, 2-acrylamido-2-methyl-propanesulfonic acid (AMPS) and acrylic acid (AA) were chosen as monomers to prepare P(AMPS- co -AA) hydrogel particles by using the SHCs as sacrificial mini-reactors. Different feed monomer molar ratios of core/shell structured CCS/P(AMPS- co -AA) hydrogel particles were synthesized through free radical polymerization. After removing the shells of the core/shell particles, the obtained P(AMPS- co -AA) particles were further used as adsorbents. The maximum adsorption capacities to the metallic ions of Ni 2+ , Cd 2+ , Cu 2+ , and Ag + were 171.6, 220.5, 366.0, and 668.4 mg/g, respectively. In addition, the adsorption amount towards methylene blue (MB) reached as high as 2970 mg/g, and the removal ratio to MB by the particle columns was over 92%. Furthermore, the particles showed excellent reusability. Thus, we provide a green and economical methodology for the preparation of tunable synthetic polymer-based hydrogel particles in aqueous solution that can be used as recyclable adsorbents for water remediation.
✓ 已验证
产品关联
DOI
高影响因子
INORGANICA CHIMICA ACTA
·
2018
·
IF 2.264
Xiao-Yin Zhang,Rui-Xue Wu,Cai-Feng Bi,Xia Zhang,Yu-Hua Fan
A new Organobismuth (V) complex, Ph 3 Bi(4-fbc) 2 [4-fbc = 4-fluorobenzoic carboxyl] was synthesized. The structure of the complex was characterized by IR spectra, elemental analysis, powder X-ray diffraction (PXRD) and single-crystal X-ray diffraction. Single crystal X-ray diffraction analysis reveals that the complex displays an 1D straight chain structure by the intermolecular hydrogen bonds (C-H⋯F and C-H⋯O), which are further constructed by π-π stacking interactions to form 2D layer and by crystal packing to form 3D supramolecular networks. Furthermore, the photodegradation properties of the complex has been investigated in organic dyes (RhB, MV, MB) and the results show that the complex has the best photocatalytic activity for RhB. The tentative photocatalytic degradations mechanism also has been discussed in details.
✓ 已验证
产品关联
DOI
高影响因子
CARBOHYDRATE POLYMERS
·
2019
·
IF 6.044
Xiaoliang Qi,Zhipeng Li,Liangliang Shen,Tao Qin,Yuna Qian,Shengzhe Zhao,Minchao Liu,Qiankun Zeng,Jianliang Shen
Wastewater treatment materials that combine high decontamination performance, ease of use and economic production are highly desirable for practical applications. Herein, we fabricated a low-cost and recyclable bio-adsorbent based on a microbial polysaccharide (salecan) for efficient removal of methyl violet (MV) from wastewater. The success fabrication and the properties (such as thermal stability, microarchitecture, mechanical strength and water uptake) of the adsorbent had been investigated, and the hydrogels were found to have tunable properties by simple adjusting the salecan dose in hydrogel composition. Adsorption data displayed that the adsorption of MV followed the pseudo second-order kinetic model (R 2 = 0.99015) and Freundlich isotherm model (R 2 = 0.99221) with a maximum adsorption capacity of 178.9 mg/g. Moreover, salecan-based hydrogels showed a good reversibility in adsorption–desorption cycles. These features indicate that salecan-based bio-adsorbent may be a promising device for dye removal from dyeing waste water.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
POLYMER
·
2014
·
IF 3.766
Xin Zhou,Yongyue Chen,Jin Han,Xuedong Wu,Gang Wang,Daoyi Jiang
Betaine ester-shell functionalized hyperbranched polyethylenimines (BEHPEI) were synthesized by Menschutkin reaction between per-N-methylated polyethylenimine (MeHPEI) and alkyl bromoacetate. BEHPEI could play dual antimicrobial roles that were, the betaine ester-shell acted as contact-based antibacterial polycations and the drug-loaded BEHPEI could controllably release the drugs due to the cleavage of the betaine ester groups under weak alkaline condition. The BEHPEI exhibited high transport capacities that per gram of BEHPEI could encapsulate 0.24–2.67 g of dyes or drugs. The model drug release experiment employing methyl orange (MO) showed that the drug release of MO-loaded BEHPEI complex occurred slowly in weak alkaline solutions and the release rate was controlled by varying pH, while the complex kept very stable under weak acid condition (pH = 3.0–7.0). BEHPEI generated from long chain alkyl bromoacetate was compatible with organic resins implying the possible usage in antimicrobial fibers and coatings. Another BEHPEI obtained from short-chain alkyl bromoacetate was water soluble and maybe used in lotion formula. The hydrolysis of BEHPEI afforded zwitterionic shell.
✓ 已验证
产品关联
DOI
高影响因子
TRANSITION METAL CHEMISTRY
·
2015
·Vol. 40
·期 7
·769-777
·
IF 1.306
Wang Hu,Zhang Xiao-Yin,Bi Cai-Feng,Fan Yu-Hua,Meng Xiang-Min
Abstract Three complexes, Zn(C 40 H 36 N 4 O 8 )·3CH 3 OH ( 1 ), Ni(C 40 H 36 N 4 O 8 )·3CH 3 OH ( 2 ) and Co(C 40 H 36 N 4 O 8 )·3CH 3 OH ( 3 ), with a sexidentate (N 2 O 4 ) symmetric bis-Schiff base ligand (C 40 H 36 N 4 O 8 = 1,2-bis(2-methoxy-6-formylphenoxy)ethane- l -tryptophan) have been synthesized and characterized by physicochemical and spectroscopic methods. The X-ray crystal structures show that the metal atoms of three complexes are all six-coordinated by two nitrogens from C=N groups, two oxygens from ether groups and two carboxylic oxygens in the mono-ligand, forming a distorted octahedral geometry. The complexes were screened as photocatalysts for the degradation of methylene blue, rhodamine B and methyl violet. All three complexes proved to be good candidates for the photocatalytic degradation of methylene blue and complexes 2–3 are also good photocatalysts for the degradation of rhodamine B. The mechanism of these photocatalytic degradations is discussed. Graphical Abstract The main characterization and photocatalytic experiment of three complexes.
✓ 已验证
产品关联
DOI
高影响因子
MACROMOLECULAR CHEMISTRY AND PHYSICS
·
2015
·Vol. 216
·期 19
·1945-1951
·
IF 2.616
Wei Ji,Guo Feng Liu,Ming Xin Xu,Chuan Liang Feng
A novel and simple strategy for preparing a redox-responsive supramolecular hydrogel coassembled from phenylalanine derivative gelator and 4,4′-dipyridine disulfide is reported in this study. The driving force for the coassembly process is intermolecular hydrogen bonds, as confirmed by various characterization methods, such as 1 H NMR, Fourier transform infrared (FTIR) spectroscopy, and circular dichroism spectroscopy. The disulfide-containing nanofibrous hydrogel is able to control over the release of encapsulated dyes in response to the reductive condition mimicking the intracellular environment like tumor tissues and should be a promising system for controllable drug release in the fields of nanomedicine and cancer therapy.
✓ 已验证
产品关联
DOI
高影响因子
ACS Sustainable Chemistry & Engineering
·
2015
·
IF 4.642
Zehong Cheng,Jie Liao,Benzhao He,Fan Zhang,Faai Zhang,Xiaohua Huang,Li Zhou
Graphene oxide (GO) is emerging as a potential adsorbent for environmental cleanup due to its attractive attributes associated with high removal efficiency toward water pollutants. However, it is difficult to separate GO from water after adsorption. Until now, the development of an effective approach that can simultaneously take advantage of the adsorption feature of GO and overcome the separation problem is still a challenge. Herein, we demonstrate a simple one-step approach to fabricate magnetic GO/poly(vinyl alcohol) (PVA) composite gels (mGO/PVA CGs), which not only exhibit convenient magnetic separation capability but also show remarkably enhanced adsorption capacity for cationic methylene blue (MB) and methyl violet (MV) dyes as compared with the one without GO (e.g., the adsorption capacities of mGO/PVA-50% and mGO/PVA-0% for MB are 231.12 and 85.64 mg/g, respectively). Detailed adsorption studies reveal that the adsorption kinetics and isotherms can be well-described by pseudo-second-order model and Langmuir isotherm model, respectively. Moreover, the adsorbent could be well regenerated in an acid solution without obvious compromise of removal efficiency. Considering the facile fabrication process and robust adsorption performance of the mGO/PVA CG, this work opens up enormous opportunities to bring GO from experimental research to practical water treatment applications. In addition, the mGO/PVA CG can act as a magnetic support for in situ growth of noble metal nanocatalyst with excellent catalytic performance, as exemplified by the synthesis of mGO/PVA-Pt catalyst in this paper.
✓ 已验证
产品关联
DOI
高影响因子
Analytical Methods
·
2014
·Vol. 6
·期 16
·6536-6540
·
IF 1.938
Jing Cao Si,Lu Lu,Zhong Feng Gao,Yu Zhang,Hong Qun Luo,Nian Bing Li
A sensitive and selective biosensor has been developed to detect the hydroxyl radical (˙OH), which was generated through the Fenton reaction. ˙OH could oxidatively damage DNA and cleave it into pieces. Based on this, taking [Ru(NH3)6]3+ as the electrochemical indicator, ˙OH was determined on a gold electrode with self-assembled DNA. The resulting electrochemical biosensor showed a wide linear range of detection from 125 pM to 625 nM with a detection limit of 80 pM and satisfactory selectivity.
✓ 已验证
产品关联
DOI
高影响因子
Chemical Science
·
2016
·Vol. 7
·期 11
·6715-6720
·
IF 9.144
Xiaoxia Le,Wei Lu,Jing Zheng,Dingyi Tong,Ning Zhao,Chunxin Ma,He Xiao,Jiawei Zhang,Youju Huang,Tao Chen
Shape memory polymers based on reversible supramolecular interactions have invoked growing research interest, but still suffer from limitations such as poor mechanical strength and finite shape memory performance. Here, we present a novel mechanical stretchable supramolecular hydrogel with a triple shape memory effect at the macro/micro scale. The introduction of a double network concept into supramolecular shape memory hydrogels endows them with excellent mechanical properties. The design of two non-interfering supramolecular interaction systems of both dynamic phenylboronic (PBA)–diol ester bonds and the chelation of alginate with Ca2+ endues the hydrogel with outstanding triple shape memory functionalities.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
FOOD CHEMISTRY
·
2017
·
IF 4.529
Lu Li,Ai-hong Peng,Zheng-zhong Lin,Hui-ping Zhong,Xiao-mei Chen,Zhi-yong Huang
A highly selective and sensitive enzyme-linked immunosorbent assay (ELISA) was developed for the detection of malachite green (MG) using a molecularly imprinted polymer (MIP) film as bionic antibody. The MIP film, based on the self-polymerization of dopamine, was fabricated on the surfaces of a 96-well microplate. It showed specific recognition for MG in aqueous solution. A direct competitive ELISA method was established with the sensitivity reaching 10.31 μg L −1 and the detection limit being 0.3 μg L −1 . The cross-reactivity of two structural analogues to MG was less than 10%. The average recovery tested by MG standard spiking was 88.8% for bass and 90.4% for water, and the relative standard deviations were less than 3.6%. All the above results indicated that the developed method could be used to detect MG in fish and water samples rapidly, specifically and accurately.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2024
·
IF 7.7
Hanyi Zhong,Shusen Li,Daqi Li,Junbin Jin,Changzhi Chen,Tingbo Mou,Zhengsong Qiu,Weian Huang
This study employed hydrothermal carbon microspheres (HCMs) as high-temperature stabilizers in drilling fluids. The HCMs were synthesized through a green hydrothermal carbonization method, using soluble starch as the precursor. The impact of HCMs on the thermal stability of xanthan, polyanionic cellulose and synthetic polymer solutions was assessed by comparing their rheological changes before and after thermal aging. The rheology and filtration properties of a polymer-based drilling fluid in the presence of HCMs were recorded before and after dynamic thermal aging at various temperatures for 16 h and static thermal aging at 200 °C for 96 h. The results demonstrated that HCMs effectively maintained stable rheology and low filtration loss following dynamic hot rolling at various temperatures and prolonged static thermal aging, surpassing the performance of conventional Na 2 SO 3 and nano-SiO 2 stabilizers. Mechanistic studies, including dissolved oxygen measurements, free radical detection, and cryo-scanning electron microscopy observations, revealed that HCMs can consume dissolved oxygen, scavenge free radicals, and physically crosslink polymers. This process prevents polymer thermo-oxidative degradation and ensures the stability of the drilling fluid. HCMs are novel, stable, sustainable, and highly effective high-temperature stabilizers for water-based drilling fluids. This study introduces a new application of biomass-derived hydrothermal carbonaceous materials for high-temperature drilling.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
CytoJournal
·
2024
·
IF 2.5
Yan Li,Zhenwei Jia,Xiaoyang Kong,Hongbo Zhao,Xiaoyan Liu,Guirong Cui,Jianmin Luo
Objective:
We currently face a sharp increase of T-cell acute lymphoblastic leukemia (T-ALL) incidence and a challenge of unmasking its complex etiology. The deoxycytidine analog 5-Aza-2’-deoxycytidine (5-Aza-dC) is currently the most common nucleoside methyltransferase inhibitor. The objective of this study was to clarify the role of 5-Aza-dC in T-ALL cell biological behaviors and phosphatase and tensin homolog deleted on chromosome ten (PTEN) expression.
Material and Methods:
T-ALL cell lines were divided into the experimental group with 5-Aza-dC solution treatment, and the control group without treatment. PTEN methylation was detected using methylation-specific polymerase chain reaction (MS-PCR). Following the measurement of cell proliferation, viability, apoptosis, invasion, migration, etc., quantitative reverse transcription-polymerase chain reaction (PCR) was conducted to detect PTEN, DNA methyl-transferases (DNMT1), DNMT3a, MBD2, and MeCP2 expressions; Western blot to detect PTEN, PI3K, AKT, and mTOR protein expressions. In addition, rescue experiments to inhibit and restore the expression of PTEN in different groups were performed for further identification of the results in the former parts.
Results:
MS-PCR results showed that in Jurkat cells, the target band was amplified using methylated primers for the PTEN gene promoter region; moreover, at 10 μmol/L of 5-Aza-dC for 24 h, PTEN methylation was completely removed without any un-methylated band observed. The experimental group had significantly lower cell proliferation and viability rates, higher apoptosis rates, decreased cell proportion in S phase, reduced invasion and migration; increased PTEN expression, decreased DNMT1, DNMT3a, MBD2, and MeCP2 mRNA expressions; and decreased PI3K, AKT, and mTOR protein expressions than those in the control group (all P < 0.05). Furthermore, according to the rescue experiment, silenced PTEN expression weakened the beneficial roles of 5-Aza-dC treatment, and resulted in significantly higher cell proliferation and viability rates, lower apoptosis rates, increased cell proportion in S phase, increased cell invasion and migration; decreased PTEN expression, elevated DNMT1, DNMT3a, MBD2, and MeCP2 mRNA expressions, and higher PI3K, AKT, and mTOR protein expressions (all P < 0.05). While restored PTEN expression enhanced functions of 5-Aza-dC treatment, leading to obviously lower cell proliferation and viability rates, higher apoptosis rates, increased cell proportion in G1 phase, and reduced cell invasion and migration; as well as increased PTEN expression, decreased DNMT1, DNMT3a, MBD2, and MeCP2 mRNA expressions, and lower PI3K, AKT, and mTOR protein expressions (all P < 0.05).
Conclusion:
Demethylation treatment with 5-Aza-dC can inhibit T-ALL cell malignant biological behaviors and enhance the sensitivity to chemotherapy agents possibly, which may be related to the inhibited expressions of DNMT1, DNMT3a, MBD2, and MeCP2, and restored expression activity of PTEN to negatively regulate the PI3K/AKT signal transduction. Our silencing and restoration of PTEN expressions further support our findings, highlighting that demethylation with 5-Aza-dC to restore the anti-tumor activity of the tumor suppressor gene PTEN may be a promising therapeutic option for treating T-ALL.
Keywords: 5-Aza-2’-deoxycytidine, T-cell acute lymphoblastic leukemia, PTEN, Tumor cell biological behaviors, Demethylation
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）