SENSORS AND ACTUATORS B-CHEMICAL
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2016
·
IF 4.758
Xueyuan Li,Xuezhong Du
The molybdenum disulfide (MoS 2 ) nanosheets supported Au-Pd bimetallic nanoparticles were synthesized using a facile thermal co-reduction method. The Au-Pd/MoS 2 nanocomposites showed good electrocatalytic activities toward the reduction of hydrogen peroxide (H 2 O 2 ) in neutral solution and the oxidation of glucose in alkaline solution, attributed to the synergistic effects of the Au-Pd bimetallic nanoparticles and MoS 2 nanosheets. The fabricated non-enzymatic electrochemical sensors exhibited the linear responses of H 2 O 2 and glucose in the concentration ranges of 0.8 μM–10 mM and 0.5–20 mM with the detection limits of 0.16 μM and 0.40 mM (S/N = 3), respectively, together with good stability and reproducibility. The Au-Pd/MoS 2 nanocomposites provide new potential materials for the development of other non-enzymatic sensors.
研究领域:
材料科学
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分析化学
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生物医学工程
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产品关联
DOI
高影响因子
BIOSENSORS & BIOELECTRONICS
·
2017
·
IF 7.78
Zengqiang Gao,Yueyun Li,Xiaobo Zhang,Jinhui Feng,Ling Kong,Ping Wang,Zhiwei Chen,Yunhui Dong,Qin Wei
A sensitive sandwich-type electrochemical immunosensor for the detection of hepatitis B e antigen (HBeAg) was successfully developed based on the gold@palladium nanoparticles (Au@Pd NPs) loaded by molybdenum disulfide functionalized multiwalled carbon nanotubes (Au@Pd/MoS 2 @MWCNTs). The resultant nanocomposites not only possessed high specific surface area and good biocompatibility , but also exhibited excellent electro-catalytical property. Au NPs functionalized porous graphene oxide (p-GO@Au) were used as sensing platforms and primary antibodies carriers, which can accelerate the electron transfer and improve the load capacity of primary antibodies (Ab 1 ), improving the sensitivity of the immunosensor. Under optimal conditions, the designed immunosensor could detect target HBeAg concentration in the range from 0.1pg/mL to 500 pg/mL, with a low detection limit of 26 fg/mL (S/N = 3) for HBeAg. Additionally, the designed immunosensor showed excellent specificity, good reproducibility and acceptable stability. The satisfactory results in analysis of human serum samples indicated that it had potential application in clinical monitoring of tumor markers.
研究领域:
生物医学工程
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分析化学
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纳米技术
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产品关联
DOI
PubMed
高影响因子
CATALYSIS TODAY
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2022
·
IF 6.562
Peng Bai,Tao Zhou,Xiaohua Wang,Xiaofei Liu,Yi Wang,Yue Wang,Edgar Muhumuza,Yonghui Zhang,Pingping Wu
A series of γ-Al 2 O 3 supported gold-palladium (Au-Pd) alloy nanoparticles (NPs) catalysts were synthesized by a one-pot approach applying mercapto-propyl-trimethoxysilane (MPTMS) as an anchoring ligand. Homogeneously dispersed Au-Pd alloy NPs were observed on the prepared catalysts and their catalytic performance in benzyl alcohol partial oxidation was investigated. Results showed that the highest benzaldehyde yield was achieved on catalyst Au-Pd/7%MPTMS-γ-Al 2 O 3 with a benzaldehyde selectivity of 90%. By establishing the structure-performance relationship, the high activity of catalysts with MPTMS modification was attributed to the anchoring and dispersion effect of MPTMS on Au-Pd NPs, while the high benzaldehyde selectivity was due to the formation of more surface Lewis acid sites after introducing MPTMS, protecting the benzaldehyde from over-oxidation to byproducts.
研究领域:
催化化学
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材料科学
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产品关联
DOI
高影响因子
Scientific Reports
·
2015
·Vol. 5
·期 1
·1-9
·
IF 5.578
Wang Liyuan,Feng Feng,Ma Zhanfang
Electrochemical redox-active species play crucial role in electrochemically multiplexed immunoassays. A one-pot method for synthesizing four kinds of new electrochemical redox-active species was reported using HAuCl 4 and Na 2 PdCl 4 as dual oxidating agents and aniline derivatives as monomers. The synthesized polyaniline derivative-Au/Pd composites, namely poly(N-methyl-o-benzenediamine)-Au/Pd, poly(N-phenyl-o-phenylenediamine)-Au/Pd, poly(N-phenyl-p-phenylenediamine)-Au/Pd and poly(3,3’,5,5’-tetramethylbenzidine)-Au/Pd, exhibited electrochemical redox activity at −0.65 V, −0.3 V, 0.12 V and 0.5 V, respectively. Meanwhile, these composites showed high H 2 O 2 electrocatalytic activity because of the presence of Au/Pd. The as-prepared composites were used as electrochemical immunoprobes in simultaneous detection of four tumor biomarkers (carcinoembryonic antigen (CEA), carbohydrate antigen 19-9 (CA199), carbohydrate antigen 72-4 (CA724) and alpha fetoprotein (AFP)). This immunoassay shed light on potential applications in simultaneous gastric cancer (related biomarkers: CEA, CA199, CA724) and liver cancer diagnosis (related biomarkers: CEA, CA199, AFP). The present strategy to the synthesize redox species could be easily extended to other polymers such as polypyrrole derivatives and polythiophene derivatives. This would be of great significance in the electrochemical detection of more analytes.
研究领域:
生物医学工程
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分析化学
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DOI
PubMed
高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
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2014
·
IF 3.84
Shan-Shan Li,Yuan-Yuan Hu,Ai-Jun Wang,Xuexiang Weng,Jian-Rong Chen,Jiu-Ju Feng
In this work, we developed a simple wet-chemical method for fabrication of worm-like Au–Pd nanostructures uniformly supported on reduced graphene oxide (Au–Pd/rGO), only with the assistance of polyethylene glycol monooleyl ether (Brij-35) as a growth-directing agent, a stabilizing agent, and a mild reducing agent. The as-prepared nanocomposites showed improved analytical performance for nitrite detection, which was further explored to construct a nitrite sensor with fast response, wide linear range from 0.05 to 1000.0 μM, low detection limit of 0.02 μM ( S / N = 3), good reproducibility, and long-term stability.
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DOI
高影响因子
MICROCHEMICAL JOURNAL
·
2026
·
IF 5.1
Qian Chen,Yutang Wang,Yuzhen Cui,Liran Lou,Zihan Yan,Haohua He,Xiangrong Zeng,Yangping Wen,Guixia Tan,Mingfang Li
Ustilaginoidea oryzae, the ascomycete fungus responsible for Rice False Smut (RFS), devastates global rice yields via rice panicles infection, threatening food security. To address the critical need for early pathogen detection, we developed an ultrasensitive electrochemical genosensor utilizing a gold‑palladium bimetallic nanoparticle (Au-PdNPs) decorated violet phosphorene/boron nitride (VP/BN) nanohybrid. The VP/BN support, synthesized via sonication-assisted liquid-phase exfoliation, enabled the uniform anchoring of Au-PdNPs through chemical reduction, creating an enhanced conductive interface. Thiolated DNA probes immobilized on Au-PdNPs via Au S bonds enabled specific recognition of U. oryzae DNA through hybridization. This design achieved exceptional sensitivity with a broad linear range (0.1 μM to 10 pM) and ultralow detection limit (3.67 pM), surpassing some traditional detection methods reported at present in speed and cost-efficiency. The genosensor exhibited high specificity against non-target sequences and delivered 96.6–98 % recovery in spiked rice samples, validating its effectiveness in practical applications. By integrating nanomaterials with electrochemical amplification, this work paves the way for field-deployable portable U. oryzae diagnostics in the future, offering a transformative strategy to mitigate economic and agricultural impacts.
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产品关联
DOI
高影响因子
ELECTROCHIMICA ACTA
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2014
·
IF 4.086
Jing-Jing Lv,Shan-Shan Li,Ai-Jun Wang,Li-Ping Mei,Jian-Rong Chen,Jiu-Ju Feng
In this work, a simple and facile strategy was developed for preparation of well-defined Au-Pd bimetallic alloyed nanoparticles uniformly supported on reduced graphene oxide nanosheets (RGOs) under solvothermal conditions. The detailed morphology, crystal structure, and composition were well characterized by (high-resolution) transmission electron microscopy (TEM), X–ray diffraction (XRD), and X–ray photoelectron spectroscopy (XPS). The as-prepared nanocomposites displayed the enhanced catalytic ability, better stability, and good methanol tolerance towards oxygen reduction reaction (ORR) in alkaline media, compared with commercial Pd black and RGOs (reduced by NaBH 4 ) catalysts. The as-developed method could be applied for synthesis of other morphology-controlled bimetallic electrocatalysts.
研究领域:
材料科学
·
电化学
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产品关联
DOI
高影响因子
Nanoscale Research Letters
·
2019
·Vol. 14
·期 1
·1-9
·
IF 3.159
Li Xiaoliang,Feng Jiangjiang,Sun Jia,Wang Zhe,Zhao Wei
TiO 2 (P25)-supported Au-Pd bimetal nanoparticles displayed excellent performance in the solvent-free benzyl alcohol catalytic oxidation. However, little research attention has been paid to investigate the effects of TiO 2 form on the catalytic activity of Au-Pd/TiO 2 . In the present research, rutile, brookite, and anatase TiO 2 were successfully synthesized and subsequently applied as the carrier to load Au-Pd nanoparticles by the deposition-precipitation method. The experimental results indicated that the benzyl alcohol conversion employing the rutile TiO 2 -supported Au-Pd catalyst is higher than the conversion of anatase and brookite TiO 2 -loaded Au-Pd catalysts. However, the Au-Pd/TiO 2 -rutile displayed the lowest and highest selectivity toward benzaldehyde and toluene, respectively. ICP-AES, XRD, XPS, and TEM were conducted to characterize these catalysts. The corresponding experimental results revealed that the excellent performance of Au-Pd/TiO 2 -rutile catalyst was attributed to both the smaller Au-Pd nanoparticle size distribution and the higher concentrations of O α and Pd 2+ species on the catalyst surface. In the recycle experiments, the Au-Pd/TiO 2 -rutile catalyst displayed lower reaction stability compared with the Au-Pd/TiO 2 -anatase and Au-Pd/TiO 2 -brookite, which might be due to the coverage of larger amount of aldehyde products on the surface.
研究领域:
化学
·
材料科学
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DOI
高影响因子
BIOSENSORS & BIOELECTRONICS
·
2014
·
IF 6.451
Wenju Xu,Huayu Yi,Yali Yuan,Pei Jing,Yaqin Chai,Ruo Yuan,George S. Wilson
In this work, a sensitive electrochemical aptasensor for thrombin (TB) based on synergetic catalysis of enzyme and porous [email protected] core–shell nanostructure has been constructed. With the advantages of large surface area and outstanding catalytic performance, porous [email protected] core–shell nanostructures were firstly employed as the nanocarrier for the immobilization of electroactive toluidine blue (Tb), hemin/G-quadruplex formed by intercalating hemin into the TB aptamer (TBA) and glucose oxidase (GOx). As a certain amount of glucose was added into the detection cell, GOx rapidly catalyzed the oxidation of glucose, coupling with the local generation of H 2 O 2 in the presence of dissolved O 2 . Then, porous [email protected] nanoparticles and hemin/G-quadruplex as the peroxidase mimics efficiently catalyzed the reduction of H 2 O 2 , amplifying the electrochemical signal and improving the sensitivity. Finally, a detection limit of 0.037 pM for TB was achieved. The excellent performance of the aptasensor indicated its promising prospect as a valuable tool in simple and cost-effective TB detection in clinical application.
研究领域:
生物化学
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医学检测
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纳米技术
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产品关联
DOI
PubMed
高影响因子
Analytical Methods
·
2018
·Vol. 10
·期 11
·1331-1338
·
IF 2.073
Huijuan Wang,Siyu Zhang,Shufang Li,Jianying Qu
Au@Pd core–shell nanoplates were synthesized successfully through the heterogeneous, epitaxial growth of Au on Pd nanoplates. The Pd nanoplates were prepared by reducing H2PdCl4 with PVP, and then served as seeds for the nucleation of Au atoms formed by reducing HAuCl4 with citric acid. Characterization of the as-prepared Au–Pd nanoplates by scanning electron microscopy revealed that a Au shell was formed around the Pd nanoplate. In order to avoid agglomeration, the Au@Pd nanoplates were loaded onto reduced graphene to give a Au@Pd/rGO nanohybrid, which exhibited excellent electrocatalytic activity towards the redox of hydroquinone (HQ) and catechol (CC) simultaneously. The linear detection ranges were 0.01–400.00 μM for HQ and 0.10–400.00 μM for CC, with detection limits of 0.01 μM for HQ and 0.10 μM for CC. Because of the excellent performance, lower detection, wider linear range, and better selectivity, the prepared Au@Pd/rGO nanohybrid has more potential applications and has an expected application in the electrochemical sensing field.
研究领域:
分析化学
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材料科学
·
电化学
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产品关联
DOI
高影响因子
BIOSENSORS & BIOELECTRONICS
·
2015
·
IF 6.409
Qian Zhou,Youxiu Lin,Yuping Lin,Qiaohua Wei,Guonan Chen,Dianping Tang
In this work, a sensitive and specific electrochemical biosensor for lead ion (Pb 2+ ) detection was developed by coupling with synergetic catalysis of porous Au–Pd bimetallic nanoparticles and hemin/G-quadruplex-based DNAzyme. In the presence of target Pb 2+ , the substrate strand was cleaved and the enzyme strand was released. Subsequently, G-rich DNA-labeled Au–Pd bimetallic nanoparticle was linked with the released enzyme strand through the helper DNA . Upon addition of hemin , a large number of hemin/G-quadruplex-based DNAzyme molecules were formed on the electrode to serve as nicotinamide adenine dinucleotide hydrogen (NADH) oxidase and peroxidase mimics. DNAzyme could catalyzed the reduction of H 2 O 2 , generated from NADH in the presence of O 2 , to produce an electrochemical signal when using thionine as the electron mediator. Introduction of porors Au–Pd bimetallic nanoparticles could enhance the detectable signal and cause the increase in the sensitivity. Experimental results showed that the variations (∆ I ) in the cathodic peak currents of the biosensor were linearly dependent on target Pb 2+ concentrations from 1.0 pM to 100 nM with a detection limit (LOD) of 0.34 pM. The excellent performance of the sensing platform indicated its promising prospect as a valuable tool for simple and cost-effective Pb 2+ detection in practical application.
研究领域:
生物化学
·
纳米技术
·
环境科学
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产品关联
DOI
PubMed
高影响因子
JOURNAL OF ALLOYS AND COMPOUNDS
·
2024
·
IF 5.8
Tianhang Liu,Kaisheng Yao,Shuaibo Li,Hang Li,Qi Wang,Tianhang Han,Aozhou Wang,Haili Zhao
Concave nanomaterials possess superior properties, but their synthesis usually requires complicated steps, specific conditions and additional reagents (surfactants, capping agents, seeds, etc.). Herein, the well-defined Au@Pd concave nanocubes (CNCs) is facile one-step fabricated in a deep eutectic solvent (DES, named reline) composed of choline chloride (ChCl) and urea. It is found that the reline is crucial to the formation of Au@Pd CNCs. Owing to the concave core-shell structures, and electronic effects between Au core and Pd shell, Au@Pd CNCs exhibited excellent catalytic performance, and recovery convenience in the selective hydrogenation of 4-nitrostyrene. Specifically, under normal temperature and pressure conditions (25°C, 0.1 MPa), 4-nitrostyrene can be completely hydrogenated to 4-nitroethylbenzene within 7.0 min. After five cycles, Au@Pd CNCs still maintain the highly catalytic activity and 100 % selectivity toward 4-nitroethylbenzene. It is expected that well-constructed Au@Pd CNCs also display advanced potentials in other applications.
研究领域:
纳米材料
·
催化化学
·
绿色化学
·
无机合成
·
加氢反应
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DOI
高影响因子
危险品化学品经营许可证（带存储）