RSC Advances
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2021
·Vol. 11
·期 47
·29590-29597
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IF 3.361
Chuanen Guo,Chengxiang Wang,Hongyan Sun,Dongmei Dai,Hongtao Gao
High-performance electrode modification materials play a crucial role in improving the sensitivity of sensor detection in electrochemical determination of heavy metals. In this study, a rGO/MoS2/CS nanocomposite modified glassy carbon electrode (GCE) was used to construct a sensitive sensor for detecting lead ions in tobacco leaves. The reduced graphene oxide (rGO) was used to increase the conductivity of the sensor, and the nano-flowered MoS2 could provide a large reaction specific surface area and a certain active site for heavy metal reaction. Chitosan (CS) was used to improve the enrichment ability of heavy metals and increase the electrocatalytic activity of electrode. Thus, an electrochemical sensor with excellent performance in reproducibility, stability and anti-interference ability was established. The stripping behavior of Pb(II) and the application conditions of the sensor were studied by square wave anodic stripping voltammetry (SWASV). The investigation indicated that the sensor exhibited high detection sensitivity in the range of 0.005–0.05–2.0 μM, and the limit of detection (LOD) was 0.0016 μM. This work can provide a fast and effective method for determination of Pb(II) in samples with low content, such as tobacco leaves.
研究领域:
分析化学
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环境科学
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PubMed
高影响因子
INORGANIC CHEMISTRY COMMUNICATIONS
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2022
·
IF 3.428
Jiangdong Gu,Qiufeng An,Jiamin Chen,Yafei He,Wenhuan Huang
To detect acetaminophen (AMP) and dopamine (DA) effectively and rapidly, the Au nanoparticles (AuNPs） were deposited on the surface of glassy carbon electrode (GCE) modified with Molybdenum dioxide-doped Reduced graphene oxide (RGO-MoO 2 ) nanosheets to form AuNPs/RGO-MoO 2 /GCE composite modified electrode (electrochemical sensor) was prepared The modified electrode was studied regarding its composition, structure and the effect of process parameters such as the electrochemical response characteristics of AMP and DA, the pH value of the buffer, the scan rate, and the sensitivity of both simultaneous detections. The results show that the synergy between AuNPs and RGO-MoO 2 nanomaterials can promote the electrochemical reaction of AMP and DA, and the oxidation peak potential differences of the two are greater than 180 mV. The linear ranges of the modified electrode are 0.05–320 μ mol/L for AMP and 0.6–260 μ mol/L for DA, and the detection limits are 7.2 nmol/L and 13 nmol/L (S/N = 3), respectively. The prepared AuNPs/MoO 2 -RGO/GCE modified electrode has a wider linear range, lower detection limit, excellent reproducibility, stability and selectivity.
研究领域:
分析化学
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生物医学工程
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材料科学
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DOI
高影响因子
FOOD CHEMISTRY
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2023
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IF 8.8
Ying Yu,Xiaodan Wang,Mingyang Li,Dengyong Liu
5′-Guanosine monophosphate (5′-GMP) is one main source of freshness in broths. Herein, an electrochemical platform based on a novel ternary nanocomposite glassy carbon electrode modified with advantageously-united gold nanoparticles, 2,2′-bipyridine hydrated ruthenium (Ru(bpy) 2 Cl 2 ) and sulfonated multi-walled carbon nanotubes (SMWCNTs)was prepared and used to detect 5′-GMP. After conditions optimization, the best performance of the electrochemical sensor was found in acidic media, including high specificity, sensitivity and selectivity. The electrochemical sensor exhibited a wide linear range under the optimal conditions. The enhanced sensitivity of this sensor was attributed to the Ru(bpy) 2 Cl 2 and functionalized SMWCNTs that provided high electrical conductivity and electrocatalytic properties during electrochemical reaction . Precise analysis of 5′-GMP in actual broth samples showed satisfactory recovery. Thus, the sensor can be used in the market and food enterprises.
研究领域:
分析化学
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电化学
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纳米技术
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食品科学
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DOI
PubMed
高影响因子
ANALYST
·
2023
·Vol. 148
·期 9
·2100-2109
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IF 4.2
Yanxue Xu,Guihua Chen,Yunting Qin,Dan Xiao
A glassy carbon electrode (GCE) was modified with graphite powder (G/GCE), and then treated with a solution of sodium peroxide for several minutes to prepare an oxidized G/GCE (OG/GCE). The OG/GCE has prominently improved responses toward dopamine (DA), rutin (RT) and acetamidophenol (APAP), of which the anodic peak current was increased by 2.4, 4.0 and 2.6 fold compared with that obtained using the G/GCE. The redox peaks of DA, RT and APAP on the OG/GCE could be separated sufficiently. The corresponding redox processes were confirmed as diffusion-controlled and parameters such as the charge transfer coefficients (α), saturating adsorption capacity (Γ*) and catalytic rate constant (kcat) were estimated. In individual detection, the linear ranges for DA, RT and APAP were 10 nM–10 μM, 1.00 nM–150 nM and 20 nM–30 μM, respectively, and the LODs for DA, RT and APAP were estimated as 6.23 nM, 0.36 nM and 13.1 nM with 3σ/S, respectively. The contents of RT and APAP in drugs were determined and agreed with the labeled contents. The recoveries of DA in serum and sweat were in the range of 91–107%, indicating that the determination results achieved by the OG/GCE are reliable. The practical use of the method was verified with a graphite-modified screen-printed carbon electrode (G/SPCE), which was also activated by Na2O2 to prepare OG/SPCE. The recovery of DA in sweat achieved using the OG/SPCE was 91.26%.
研究领域:
电化学
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分析化学
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材料科学
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PubMed
高影响因子
BIOSENSORS & BIOELECTRONICS
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2023
·
IF 12.6
Yongfeng Chen,Yufeng Sun,Ruiqiang Wang,Geoffrey I.N. Waterhouse,Zhixiang Xu
Herein, we prepared a self-crosslinked conductive molecularly imprinted gel (CMIG) using cationic guar gum (CGG), chitosan (CS), β-cyclodextrin (β-CD), amaranth (AM) and multi-walled carbon nanotubes (MWCNTs) by a simple one-pot low temperature magnetic stirring method. The imine bonds, hydrogen-bonding interactions and electrostatic attractions between CGG, CS and AM facilitated CMIG gelation , while β-CD and MWCNTs enhanced the adsorption capacity and conductivity of CMIG, respectively. Next, the CMIG was deposited onto the surface of a glassy carbon electrode (GCE). After selective removal of AM, a highly sensitive and selective CMIG-based electrochemical sensor was obtained for AM determination in foods. The CMIG allowed specific recognition of AM and could also be used for signal amplification , thus improving the sensitivity and selectivity of the sensor. Due to the high viscosity and self-healing properties of the CMIG, the developed sensor was very durable retaining a 92.1% of original current after 60 consecutive measurements. Under optimal conditions, the CMIG/GCE sensor showed a good linear response for AM detection (0.02–150 μM) with a limit of detection of 0.003 μM. AM recovery tests were performed in milk powder and white vinegar samples, yielding satisfactory recoveries (89.00%–111.00%). Furthermore, the levels of AM in two kinds of carbonated drinks were analyzed with the constructed sensor and an ultraviolet spectrophotometry method, with no significant difference found of the two methods. This work demonstrates that CMIG based electrochemical sensing platforms allow the cost-effective detection of AM, with the CMIG technology likely being widely applicable to the detection of other analytes .
研究领域:
分析化学
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电化学
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食品科学
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材料科学
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PubMed
高影响因子
MICROCHEMICAL JOURNAL
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2026
·
IF 5.2
Sadia Yousaf,Usman Naseer,Mehwish Shah,Qingyun Cai
Arsenic contamination is a major threat to public health and environmental protection, necessitating the development of a rapid, sensitive, and reliable analytical approach for its monitoring. Here, a cauliflower-like gold‑silver nanostructured modified glassy carbon electrode (CF-AuAg/GCE) was fabricated as a novel electrochemical sensor for ultrasensitive determination of total arsenic using square-wave anodic stripping voltammetry (SWASV). The properties of the proposed sensor were characterized by scanning electron microscopy (SEM), X-ray photoelectron spectroscopy (XPS), X-ray diffraction (XRD), cyclic voltammetry (CV), electrochemical impedance spectroscopy (EIS), and square-wave anodic stripping voltammetry. The CF-AuAg/GCE has a high electrochemically active surface area (ECSA) and good electrical conductivity for efficient arsenic determination. Meanwhile, the proposed sensor exhibits excellent anti-interference properties, repeatability, long-term stability, and reproducibility. Under optimal conditions, peak current was proportional to arsenic concentration over 0 to 300 μg/L linear dynamic range (LDR), with a limit of detection (LOD) of 0.06 μg/L. Finally, CF-AuAg/GCE was successfully applied to determine total arsenic in industrial wastewater, medicinal herbs (licorice root, ginseng root, astragalus root, and chrysanthemum flower), and artificial saliva, yielding high recoveries and good practicability. The excellent electrochemical sensing performance, with a low detection limit and high sensitivity at the μg/L level, is attributed to the unique structure of CF-AuAg/GCE and fast electron-transfer kinetics. Therefore, CF-AuAg/GCE is a robust and promising approach for arsenic determination in environmental and biological matrices. Download: Download high-res image (150KB) Download: Download full-size image
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高影响因子
MICROCHEMICAL JOURNAL
·
2024
·
IF 4.9
Yujun Zhong,Zhiyang Li,Anlin Zhang,Yuqing Peng,Hao Zhou,Yaping Guo,Danqing Lu,Lianwu Xie,Shuyun Shi
A novel electrochemical sensor MIP/AuNPs/GCE was developed by depositing gold nanoparticles and electropolymerizing molecularly imprinted film on the surface of glassy carbon electrode (GCE) for highly sensitive detection of neutral phosmet residues in fruits and vegetables. Scanning electron microscopy, energy dispersive spectroscopy, atomic force microscopy, cyclic voltammetry and electrochemical impedance spectroscopy were used to characterize the imprinted sensor. The results showed that the imprinted film on GCE was evenly prepared with better specific recognition of phosmet on MIP/AuNPs/GCE than that on bare GCE. Several parameters including deposition time, functional monomer and its molar ratio, scanning cycles, and elution time were optimized in detail. The linear range of the MIP/AuNPs/GCE prepared in this work was 0.020–4.0 nmol/L with limit of detection of 0.010 nmol/L, which was much lower than MIP/GCE (0.17 nmol/L). The identification mechanism of MIP/AuNPs/GCE for phosmet was also confirmed as adsorption-diffusion model with effective surface area increasing after mediated by AuNPs. Selectivity, reproducibility and repeatability of the MIP/AuNPs/GCE were acceptable. The recovery of applying the sensor to detect PM in real samples ranged from 91.40 % to 107.3 %, which agreed well with those of HPLC. The method of developing MIP/AuNPs/GCE sensor herein could be extended to detecting other neutral pesticide residues in food and environment.
研究领域:
分析化学
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环境科学
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食品科学
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DOI
高影响因子
JOURNAL OF APPLIED POLYMER SCIENCE
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2023
·Vol. 140
·期 14
·e53686
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IF 3
Yanwei Zhang,Hong Wang,Yaru Liu,Baolong Niu,Wenfeng Li
Accurate measurement of hydrogen peroxide is of great significance in monitoring human diseases and environmental safety. At present, there are a variety of testing methods, among which the use of electrochemical sensors to accurately measure hydrogen peroxide has gradually become a research hotspot. In this article, phytic acid (PA) with dual functions of doping and cross-linking and HCl with strong ionization capacity was introduced as dopants to co-doping polyaniline, and polyaniline hydrogel with a three-dimensional network structure was prepared. The influence of the HCl/PA co-doping ratio on conductive polyaniline hydrogel (CPAniH) was explored. The synthesis process and mechanism of HCl/PA-CPAniH were analyzed and explained. In addition, the conductivity and mechanism of HCl/PA-CPAniH, as well as the hydrogel characteristics were characterized and studied. A new electrochemical sensor based on polyaniline hydrogel and silver nanoparticles was constructed to detect hydrogen peroxide. The sensor has a good linear relationship, a wide linear range, and a high-detection limit for H 2 O 2 . In addition, it also shows that HCl/PA-CPAniH is a good interface material for electrochemical sensors and has a certain application potential.
研究领域:
材料科学
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生物医学工程
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分析化学
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DOI
高影响因子
ANALYTICAL LETTERS
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2023
·
IF 2
Jie Zhang,Yulin Fu,Lin Li,Liqiang Yan,Xiongzhi Wu,Chenghong Lei
Ascorbic acid (AA) determination is of high importance in the diagnosis and treatment of diseases. Herein, we report a new ratiometric electrochemical sensor for ascorbic acid using a glassy carbon electrode (GCE) modified with a copper nanoparticle@resin nanosphere nanocomposite (CuNPs@RNS). The ratiometric strategy was established by immobilizing an internal reference (thionine) on the modified electrode using cyclic voltammetry (CV). The performance of the modified electrodes as well as the newly established ratiometric strategy was explored. The sensing platform had good electrocatalytic ability, reproducibility, and stability. In addition, the ratiometric strategy significantly improved the performance of electrochemical sensing with a wide linear range (0.0837 to 15.5 μM) and a low detection limit of 0.0279 μM under the optimal conditions. The original ratiometric electrochemical sensor was successfully applied to monitor ascorbic acid in tablets and urine. These results showed that the sensor provides a new strategy and broad prospects for biomolecular sensing with reliability and high sensitivity.
研究领域:
分析化学
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生物医学工程
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电化学传感
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DOI
高影响因子
BIOSENSORS & BIOELECTRONICS
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2021
·
IF 10.618
M.R. Ali,M.S. Bacchu,M.A.A. Setu,S. Akter,M.N. Hasan,F.T. Chowdhury,M.M. Rahman,M.S. Ahommed,M.Z.H. Khan
Due to the epidemics of emerging microbial diseases worldwide, the accurate and rapid quantification of pathogenic bacteria is extremely critical. In this work, a highly sensitive DNA-based electrochemical biosensor has been developed to detect Vibrio cholerae using gold nanocube and 3-aminopropyltriethoxysilane (APTES) modified glassy carbon electrode (GCE) with DNA carrier matrix. Electrochemical impedance spectroscopy (EIS), cyclic voltammetry (CV), Fourier transform infrared spectroscopy (FTIR), scanning electron microscope (SEM) experiments were performed to interrogate the proposed sensor at each stage of preparation. The biosensor has demonstrated high sensitivity with a wide linear response range to target DNA from 10 −8 to 10 −14 ( R 2 = 0.992 ) and 10 −14 to 10 −27 molL −1 ( R 2 = 0.993 ) with a limit of detection (LOD) value of 7.41 × 10 −30 molL −1 ( S/N = 5 ). The biosensor also exhibits a selective detection behavior in bacterial cultures that belong to the same and distant genera. Moreover, the proposed sensor can be used for six consecutive DNA assays with a repeatability relative standard deviations (RSD) value of 5% ( n = 5). Besides, the DNA biosensor shows excellent recovery for detecting V. cholerae in poultry feces, indicating that the designed biosensor could become a powerful tool for pathogenic microorganisms screening in clinical diagnostics, food safety, and environmental monitoring.
研究领域:
微生物学
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电化学
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生物技术
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环境科学
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临床诊断
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DOI
PubMed
高影响因子
Journal of Environmental Chemical Engineering
·
2024
·
IF 7.4
Peipei Song,Zhirui Fan,Shuai Sun,Chengye Sun,Jun Wang
In recent years, lead (Pb) contaminated soil has caused irreversible damage to human beings. It is urgent to develop a novel technology for accurate detection of Pb in the soil solution. Herein, a new electrochemical sensor was fabricated. Fe/ZIF-8 was used as the modification material, gold nanoparticles (AuNPs) were electrodeposited, and DNAzyme was applied on the surface as the probe. Under the optimum conditions (DNAzyme concentration of 1 μmol, fixation time of 4 min, incubation time of 17 h and reaction time of 30 min), the detection range was 5×10 −12 ∼ 5×10 −5 M, and the minimum detection limit was 10 −13 M (3δ). Furthermore, the electrochemical sensor demonstrated outstanding anti-interference ability to common cations, anions, organic compounds and other interference factors. After four consecutive tests, the relative standard deviation (RSD) was only 0.39%, and it still displayed excellent reproducibility with 0.69% of RSD. After 20 days, the sensor’s response to Pb 2+ remained at 93.58%. In addition, the sensor could accurately detect Pb 2+ in the actual soil solutions, and the recoveries of the samples ranged from 92% to 109.4%. In conclusion, this electrochemical sensor can specifically detect Pb 2+ in the soil solution with enhanced sensitivity, anti-interference capability and stability, which is of great significance for Pb 2+ detection in the field.
研究领域:
环境科学
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分析化学
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纳米技术
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DOI
高影响因子
ANALYST
·
2026
·
IF 3.6
Sadia Yousaf,Usman Naseer,Mehwish Shah,Liufang Chen,Hailong Yan,Qingyun Cai
Efficient and sensitive monitoring of toxic ions, particularly arsenic in actual water samples and various food matrices, is crucial for effective health risk management. In this work, a glassy carbon electrode (GCE) is modified with the nano-granular network of gold-copper (NG-AuCu/GCE) for total arsenic determination in actual water and food matrices. Square wave anodic stripping voltammetry (SWASV) using NG-AuCu/GCE confirms the successful determination of total arsenic with negligible interference from commonly coexisting ions. Gold-copper nano-granular network provides a large surface area, resulting in a high sensitivity with a limit of detection (LOD) of 0.03 ppb only. Our modified sensor exhibited an excellent response and a linearity from 0 to 500 ppb. Eventually, the NG-AuCu/GCE was successfully applied to actual water samples and various food matrices for total arsenic determination with high recoveries. Our proposed approach is a simpler, more reliable, and faster alternative to existing methods, while the proposed sensor is cost-effective and environmentally friendly. Moreover, it demonstrates promising efficiency in the rapid determination of total arsenic, with excellent anti-interference properties and long-term stability.
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高影响因子
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