MATERIALS RESEARCH BULLETIN
·
2019
·
IF 3.355
Zheng Gong,Jian Yang,Hancheng Zhu,Duanting Yan,Chunguang Liu,Changshan Xu,Yuxue Liu
Gd 3+ and Cr 3+ codoped zinc gallogermanate (ZGGO:Cr 3+ , Gd 3+ ) nanoparticles were prepared by a hydrothermal method in combination with a subsequent vacuum annealing. It is found that Gd 3+ doping not only endows ZGGO:Cr 3+ nanoparticles with magnetic property, but also results in the decreased nanoparticle size and the enhanced near infrared (NIR) afterglow intensity. Strikingly, amino group functionalized SiO 2 layer coating enabling Gd 3+ doped ZGGO:Cr 3+ nanoparticles well dispersed in water enhances persistent luminescence which is because of the weakened quenching effect of OH − groups in water. Validation of high-quality bioimaging was demonstrated using the surface functionalized Gd 3+ doped ZGGO:Cr 3+ nanoparticles dispersed in human serum albumin (HSA). In particular, it is found that the longitudinal relaxivity (7.33 s −1 (mM) −1 ) of Gd 3+ doped ZGGO:Cr 3+ nanoparticles is higher than that of commercial magnetic resonance imaging (MRI) contrast agent (Gd-DTPA) and it leads to the high-quality in vitro T 1 -weigthed images.
研究领域:
材料科学
·
医学影像学
·
纳米技术
✓ 已验证
DOI
高影响因子
INORGANIC CHEMISTRY
·
2022
·
IF 5.436
Yi Zhang,Yanjie Liang,Xihui Shan,Dongxun Chen,Shihai Miao,Ruiqi Shi,Fei Xie,Weili Wang
Persistent phosphors emitting in the narrowband ultraviolet-B (NB-UVB) spectral region have aroused significant interest, owing to their special self-illuminating feature in realizing many advanced technological applications under excitation-free conditions, such as dermatological therapy and invisible optical tagging. Here, we focus our discussion on a new Gd3+-doped persistent phosphor, Sr2P2O7:Gd3+, which exhibits long-lasting NB-UVB persistent luminescence peaking at 312 nm for more than 24 h after charging by an X-ray beam. The NB-UVB light emission from the charged Sr2P2O7:Gd3+ phosphor can be clearly detected by a UVB camera in bright indoor environment. More importantly, the enhancement of NB-UVB afterglow intensity and decay time can be observed under continuous photostimulation of polychromic indoor ambient light. Furthermore, applying charged Sr2P2O7:Gd3+ phosphors as invisible optical taggants, clear and interference-free recognition of the encrypted message and location of different objects have been realized due to the lack of UVB light in bright indoor environment. The as-prepared Sr2P2O7:Gd3+ persistent phosphor is expected to offer new directional solutions for the development and application of ultraviolet luminescence technology.
研究领域:
材料科学
·
发光材料
·
光学工程
·
光子学
·
生物医学应用
✓ 已验证
DOI
高影响因子
COMPOSITES SCIENCE AND TECHNOLOGY
·
2022
·
IF 9.879
Jin-Ke Wu,Wei-Wei Zhang,Jian-Jun Wang,Jiang-Tao Zhu,Yu-Hang Zhang,Yi-Xuan Li,Ya-Jun Luo,Ya-Fei Zhang,Li-Xing Dai,Chuan-Xiang Qin,Jun Sun,Jia-Jia Chen
In this work, Gd 3+ ionic nano-aggregate clusters were introduced into metallo-polyelectrolytes to balance the conflicts between high mechanical robustness and X-ray attenuation of flexible shielding materials. The segmented polyurethanes (PUs) containing main-chain bisferrocene and pendant sulfonates in hard segments is applied as a macromolecular template for the subsequent self-assembly with Gd 3+ . Rare earths aggregate into dynamic clusters about 2.2 nm, which is beneficial to improve the radiation attenuation ability and mechanical properties of materials. The hierarchical noncovalent interactions (ionic interactions, coordination interactions, hydrogen bonds , and ferrocene-metal interactions, etc.) in the aggregate PUs enable the co-existence of high mechanical strength , large stretchability, and fast radiation dissipation. As a result, this Gd 3+ hybrid bisferrocene-based PU demonstrates extremely high tensile properties (breaking stress = 27.8 ± 0.2 MPa, breaking strain = 576 ± 7%) as well as super atomic shielding efficiency (14.39 cm 2 g −1 ) at 65 keV.
研究领域:
材料科学
·
辐射防护
·
聚合物化学
·
纳米技术
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF LUMINESCENCE
·
2023
·
IF 3.6
Shaolian Sun,Shan Shao,Wuyang Fan,Wenhu Zhang,Fan Xu,Haoming Wei,Bingqiang Cao,Yangqing Wu
The synthesis of efficient nano-scintillators is of great significance for the development of X-ray imaging and other applications. Here, X-ray excited afterglow rare earth nanoparticles β-NaLuF 4 :Gd 3+ /Tb 3+ are investigated. The X-ray-induced luminescence intensity and afterglow duration of NaLuF 4 :Gd 3+ /Tb 3+ nanoparticles are effectively improved by Ca 2+ doping. The optimal luminescence and afterglow performance are achieved when Ca 2+ doping ratio reaches 10%. The change of crystal field symmetry is the main reason for the improvement of luminescence performance. According to the thermoluminescence curve, it is proved that Ca 2+ doping increases the trap concentration and further enhances the afterglow. This study provides the research basis for the application of persistent luminescence materials in biomedical and other fields.
研究领域:
材料科学
·
医学影像
·
生物医学工程
✓ 已验证
产品关联
DOI
高影响因子
Theranostics
·
2017
·
IF 8.766
Feng Fan,Yue Yu,Fei Zhong,Meng Gao,Tianmeng Sun,Jiaxin Liu,Huimao Zhang,Haisheng Qian,Wei Tao,Xianzhu Yang
Imaging-guided cancer therapy, which integrates diagnostic and therapeutic functionalities into a single system, holds great promise to enhance the accuracy of diagnosis and improve the efficacy of therapy. Specifically, for photodynamic therapy (PDT), it is highly desirable to precisely focus laser light onto the tumor areas to generate reactive oxygen species (ROS) that are cytotoxic tumor cells and avoid light-associated side effects. Herein, a distinct three-layer nanostructured particle with tumor acidity-responsiveness (S-NP) that encapsulates the photosensitizer chlorin e6 (Ce6) and chelates Gd 3+ is successfully developed for fluorescence/magnetic resonance (MR) dual-model imaging-guided precision PDT. We show clear evidence that the outer PEG layer significantly prolongs circulation time, and the inner poly(ε-caprolactone) (PCL) core can physically encapsulate Ce6. More interestingly, the middle layer of the S-NP, acting as a molecular fence to keep Ce6 in the circulation system, was dismantled by the slightly acidic tumor microenvironment. Afterwards, the PEG shell is deshielded from the S-NP at the tumor tissue, resulting in improved cell uptake, enlarged MR signal intensity, rapid release of Ce6 within tumor cells, and elevated PDT efficacy. Our results suggest that tumor-acidity-responsive nanoparticles with fine design could serve as a theranostic platform with great potential in imaging-guided PDT treatment of cancer.
研究领域:
生物医学工程
·
癌症治疗
·
分子影像学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF LUMINESCENCE
·
2020
·
IF 3.28
Wanggui Ye,Yuzhen Wang,Chong Zhao,Zicheng Wen,Zhiquan Cao,Zhijun Cao,Xiaofei Shen,Yingkui Li,Xuanyi Yuan,Chong Wang,Chaoyang Ma,Yongge Cao
Herein, we propose a series of unprecedented Dy 3+ -doped triclinic Gd 2 Ge 2 O 7 nanophosphors by solid-state reaction method. As the doping concentration arises, the XRD peaks shift to large angle and absorption edge energy increases from 5.42 to 5.45 eV. Under 275 nm excitation, Dy 3+ ions are sensitized by Gd 3+ and exhibits two strong emission peaks at 484 and 575 nm as well as two weak emission peaks at 455 and 663 nm. The interaction between Gd 3+ and Dy 3+ is dipole-dipole interaction and the critical distance is estimated to be 16.58 Å. For sample with optimal doping concentration, along with temperature increases from 300 to 570 K, PL intensity of 484 nm and 575 nm slightly decreases, while that of 455 nm sharply increased about 4 times. The interval of thermally coupled levels Dy 3+ : 4 F 9/2 and 4 I 15/2 is estimated to be 1317 cm −1 . Population at Dy 3+ : 4 I 15/2 , 4 F 9/2 energy levels in GGO lattice can be attributed to thermally-coupled levels of Dy 3+ and phonon-assisted absorption transition of Gd 3+ . The temperature sensitivity of 1.5 at% Dy 3+ ions in GGO is calculated to be as high as 2029.5/T 2 . This work paves a new way to search for high performance optical thermometric materials based on phonon-assisted transition and energy-transfer mechanism.
✓ 已验证
DOI
高影响因子
Journal of Materials Chemistry C
·
2025
·Vol. 13
·期 19
·9747-9755
·
IF 5.1
Chunli Peng,Jueran Cao,Baoling Tang,Tianrui Li,Mingkai Wei,Haoran Zhang,Xuejie Zhang,Mingtao Zheng,Maxim S. Molokeev,Bingfu Lei
Far-red (FR) light is involved in plant photomorphogenesis as a light signal. To realize the match between the absorption peak (730 nm) of a plant photosensitive pigment (Pfr) and the emission spectrum (708 nm) of a Y3Ga4.87O12:0.13Cr3+ (YGO:0.13Cr3+) phosphor, in this study, we employed an ‘A site modification-B site response’ crystal-field-modulation strategy using the garnet structure Y3Ga5O12, where doping large radius Gd3+ at the A site induced [YO8] polyhedral expansion and triggered [GaO6] octahedral distortion, thereby weakening the crystal field strength to achieve a red shift in the spectrum. The optimized Gd1.2Y1.8Ga4.87O12:0.13Cr3+ (GYGO:0.13Cr3+) phosphor exhibited high external quantum efficiency (34%) and excellent thermal stability (85.5% intensity at 423 K) under 450 nm excitation. Its emission peak at 726 nm was significantly close to 730 nm, while its luminescence intensity was improved by 141% that of the original system. It was successfully fabricated as an FR pc-LED device, achieving a 36.86 mW output power and 13.5% photoelectric efficiency at 100 mA current. Lettuce growth experiments showed that the device enhanced biomass production by 30% through precise spectral adaptation. The present work can promote the leap in plant lighting from rough supplementation to spectral customization through the whole chain of structural aberration–photoelectricity–biological effects.
研究领域:
植物生理学
·
光学材料
·
园艺照明
·
光子学
·
材料科学
·
农业技术
✓ 已验证
产品关联
DOI
高影响因子
Functional Materials Letters
·
2023
·
IF 1.3
Chaoqian Qin,Jinghong Du,Jiaxing Chen,Jiarui Yang,Shengyang He
Titanium dioxide nanotube arrays doped with Mo 6 + , Gd 3 + , and Mo 6 + - Gd 3 + were prepared by anodic oxidation combined with a two-step electrochemical method. The crystalline structure, surface morphology, light absorption properties, and crystalline transformation process were characterized using XRD, SEM, UV–Vis, DSC, and FT-IR. The results show that Mo 6 + and Gd 3 + single doping of TiO 2 can promote the transformation of amorphous TiO 2 to anatase and inhibit the transformation of anatase phase to rutile, but Mo 6 + – Gd 3 + co-doping promotes both phase transformations, and the anatase compositions of the TiO 2 heat-treated at 450 ∘ C were all over 91%; The tube diameters of TiO 2 nanotubes were all around 60–70 nm; the Mo 6 + - and Gd 3 + -doped TiO 2 light absorption peaks were all significantly red-shifted, with the most obvious change in the Mo 6 + – Gd 3 + co-doping, where the forbidden bandwidth was reduced to 3.01 eV; The degradation rate of pure TiO 2 photocatalytic degradation of methylene blue for 8 h was only 41.9%, while the degradation rate of Mo 6 + – Gd 3 + co-doped TiO 2 was as high as 91.51%; Mo 6 + , Gd 3 + , single doping and co-doping could increase the amount of •OH, •OOH adsorbed on the surface of TiO 2 , which led to the improvement of catalytic performance.
研究领域:
材料科学
·
纳米技术
·
环境科学
✓ 已验证
DOI
高影响因子
Science China-Materials
·
2023
·Vol. 66
·期 10
·4090-4099
·
IF 8.1
Yang Kaidong,Yang Yating,Sun Dongquan,Li Shihua,Song Xiaorong,Yang Huanghao
X-ray nanoscintillator-based photoresponsive therapy is emerging as a promising strategy to treat in vivo tumors, necessitating the development of nanoscintillators with X-ray-excited luminescence in the ultraviolet region (UV-XEL) for the photoactivation of therapeutic precursors. However, it remains a challenge to achieve high-efficiency X-ray-activated tumor therapy due to the limited UV-XEL efficacy. Herein, we developed novel Gd 3+ /Ce 3+ -codoped LiLuF 4 nanoscintillators with strong UV-XEL for in vivo tumor therapy. Significantly, through optimization of host materials, dopants, and energy transfer process, the developed nanoscintillators enabled effective enhancement of UV-XEL (up to 18-fold) as compared with the traditional Ce 3+ -doped counterparts. As a proof-of-concept study to evaluate the in vivo therapeutic applications of the nanoscintillators, we integrated them with nitric oxide (NO) precursors for controllably generating NO upon the X-ray exposure, achieving superior in vivo antitumor effect upon X-ray-induced synergetic NO therapy and radiotherapy. Moreover, X-ray-activated NO therapy can inhibit tumor metastasis into liver to suppress tumor regrowth and prolong mice survival. This work might motivate future development of X-ray nanoscintillators for treating diseases in deep tissue.
研究领域:
生物医学工程
·
放射治疗学
·
纳米医学
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF LUMINESCENCE
·
2022
·
IF 4.171
Chao Zhou,Denghao Li,Lei Lei,Gongxun Bai,Huanping Wang,Xiaofeng Liu,Shiqing Xu,Jianrong Qiu
High energy X-rays have been widely employed in biological and medical fields because of its unlimited penetration depth in biological tissues and near-infrared (NIR) emission is considered as a preferred signal in bioimaging and biosensing. However, it remains a big challenge for nanoparticles to emit high intensity NIR light upon X-ray radiation due to the presence of defects and material's intrinsic low X-ray absorption ability. In this work, we prepare NaLuF 4 : Gd, Tm nanoparticles with different doping levels of Gd 3+ and Tm 3+ ions and systematically study the NIR emission properties under X-ray irradiation. NaLuF 4 : 20Gd, 1 Tm nanoparticles exhibits ∼3.5 times stronger radioluminescence at 800 nm as compared to solely Tm 3+ doped nanoparticles. When X-ray induced electrons and holes recombine, Gd 3+ ions serve as energy absorber and transfer the optical energy to Tm 3+ ions. Excessive amount of Gd 3+ ions will result in efficient energy flow to defects and apparent decreased NIR emission which can be confirmed by the lifetime curves of 3 H 4 states of Tm 3+ ion. We further examine the X-ray-induced afterglow intensity of nanoparticles at 800 nm and demonstrate conceptually bioimaging with a deep penetration depth using the developed nanoparticles. The clear picture taken by a NIR camera indicates the NaLuF 4 : 20Gd, 1 Tm nanoparticles can be used a promising probe for X-ray luminescence optical imaging .
研究领域:
材料科学
·
纳米技术
·
生物医学成像
·
光学材料
·
辐射探测
✓ 已验证
DOI
高影响因子
Nanoscale
·
2018
·Vol. 10
·期 28
·13402-13409
·
IF 7.233
Sihan Ma,Jiaxin Zhang,Shibo Xia,Wenyan Yin,Yanxia Qin,Runhong Lei,Jianglong Kong,Linqiang Mei,Juan Li,Gengmei Xin,Gongping Li
Designing nanosized multi-modality contrast agents for high-resolution imaging is challenging since most agents are only useful for single-mode imaging. In this work, we successfully synthesized biocompatible polyethylene glycol (PEG-) and L-glutamine (GLN-) modified Ba4Yb3F17:Lu3+,Gd3+ nanoparticles (LNPs@PEG@GLN) that can be employed as a multi-modality contrast agent. Fluorescence dye-modified LNPs@PEG@GLN nanoparticles can be used for computed tomography (CT), magnetic resonance imaging (MRI), and fluorescence imaging (FI). They display high X-ray absorption, outstanding T2-weighted imaging capability, and good fluorescence uptake. Furthermore, LNPs@PEG@GLN enhances contrast efficiencies for different imaging modalities in vivo. Interestingly, LNPs@PEG@GLN is a promising agent for CT angiography. These nanoparticles could be a promising contrast agent for multi-modality imaging and diagnosing vascular diseases.
研究领域:
医学影像学
·
纳米医学
·
分子影像学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Materials
·
2024
·Vol. 17
·期 6
·1258
·
IF 3.1
Min Liu,Yansen Zhang,Song Hu,Guohong Zhou,Xianpeng Qin,Shiwei Wang
Ce-doped gadolinium gallium aluminum oxide (Ce: GGAG) precursors were first prepared by the microwave-assisted homogeneous precipitation method (MAHP). Thermal gravity-differential thermal analysis (TG-DTA), X-ray diffraction (XRD), specific surface area analysis (BET) and field emission scanning electron microscopy (FE-SEM) were employed to investigate the crystal structure, phase evolution and morphologies of the Ce: GGAG precursors and powders. The influence of Ga ion concentration in the salt solution on the properties of Ce: GGAG powders was investigated. All the precursors were transformed into single-phase GGAG after being calcined at 950 °C in a furnace for 3 h. Monodispersed Ce: GGAG powders were obtained as the Ga ion concentration was lower than 0.06 mol/L. Single-phase and dense Ce: GGAG ceramics were obtained after sintering at 1600 °C in a flowing oxygen atmosphere for 10 h. Specifically, the Ce: GGAG ceramic reached its maximum density of ~6.68 g/cm3, which was close to its theoretical density of 6.70 g/cm3, and exhibited the highest optical transmittance of 65.2% at 800 nm after hot isostatic pressing sintering (HIP) as the Ga ion concentration was 0.02 mol/L. The decay time and light yield of the GGAG ceramic were 35 ns and 35,000 ± 1250 ph/MeV, respectively, suggesting that Ce: GGAG ceramics prepared using MAHP-synthesized nanopowders are promising for scintillation applications.
研究领域:
材料科学
·
无机化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）