SEPARATION AND PURIFICATION TECHNOLOGY
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2026
·
IF 9.1
Liuyang Su,Wensi Zhang,Nilupuli Pabasara Nandasiri Solon Achchige,Yue Zhou,Susu Long,Zhaohui Wang,Xiaozu Wang,Zhaoliang Cui
Membrane-based dehumidification offers an energy-efficient alternative to conventional methods but requires membranes that concurrently exhibit high water vapor permeability and robust mechanical strength, a combination that is challenging to achieve. While sulfonated polyether ether ketone (SPEEK) provides excellent hydrophilicity for vapor transport, its high swelling tendency often compromises mechanical integrity. This work aims to optimize this critical performance–strength balance through microstructure engineering of SPEEK/polyethersulfone (PES) blend membranes fabricated via non-solvent induced phase separation (NIPS). By modulating the coagulation bath and the SPEEK/PES blending ratio, precise control over membrane morphology is demonstrated, enabling a tailored transition from finger-like to sponge-like pore structures. This structural evolution directly governs the key membrane properties: reducing the SPEEK content enhances mechanical strength but diminishes hydrophilicity and dehumidification efficiency. The optimal dehumidification performance of the 4:6 SPEEK/PES blend arises from the synergistic effect of enhanced hydrophilicity and optimized asymmetric microstructure, where morphological regulation via skin layer thinning plays a dominant role in mass transfer enhancement. The findings establish a rational design strategy for polymer blend membranes, demonstrating that synergistic microstructural control enables effective optimization of the performance–strength balance within the inherent trade-off framework for air dehumidification applications.
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高影响因子
Journal of Environmental Chemical Engineering
·
2024
·
IF 7.4
Mengyu Ren,Tianya Chen,Junxia Chang,Lin Ding,Feilong Hu,Yong Zhang,Shujuan Yang
The study focused on the preparation of spongy polyether sulfone (PES) ultrafiltration membrane and investigated the effects of N-vinylpyrrolidone (NVP) and air exposure time on membrane properties. NVP was used as a pore-forming additive to create interconnected pores in the membrane structure, leading to higher water permeability. Furthermore, longer air exposure generally improved membrane porosity and performance. However, excessive exposure led to membrane shrinkage and reduced mechanical strength . The incorporation of NVP and air exposure effectively mitigates the trade-off effect between permeability and selectivity. this work might provide an effective process for preparing spongy PES ultrafiltration membrane with outstanding antifouling performance, high throughput, and great stability. Therefore, an optimized composite membrane was confirmed by combining the addition of 10 wt% NVP with 40 s air exposure, referred to as M4. The water flux of the M4 membrane reached 797.62 L·m −2 ·h −1 , which was 1.9 times higher than that of a pure PES membrane. Additionally, the rejection rate of bovine serum albumin (BSA) increased from 57.97 % to 95.89 % compared to the pure PES membrane. The spongy PES ultrafiltration membrane exhibited desirable properties for protein separation and wastewater treatment , making them promising materials for various applications in the field.
研究领域:
材料科学
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环境工程
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生物技术
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高影响因子
MICROPOROUS AND MESOPOROUS MATERIALS
·
2023
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IF 5.2
Lei Wu,Mengmeng Zhao,Qiuyan Ye,Xian Xin,Kun Zhang,Yongnan Chen,Ziwei Wang
Electrochemical synthesis of polymer/MOF composite membranes holds great potential for practical applications, yet the preparation of flexible and dense MOF layers remains a challenge, which is crucial for achieving practicality. Herein, a novel ultra-flexible polyethersulfone (PES)/Cu-based metal–organic framework (HKUST-1) composite membrane has been fabricated via an electrochemical synthesis method. Various reaction conditions, including voltage, stirring speed, and reaction time, were systematically investigated to elucidate their influence on crystal growth and the resulting membrane uniformity. The characterization results showed that high voltage and moderate stirring as well as are conducive to obtaining uniform fine crystals. Additionally, a relatively extended reaction time is advantageous for achieving a more continuous and denser MOFs membrane with outstanding flexibility. The optimized membrane possesses an excellent separation flux (2.81 × 10 3 ±32 L m −2 h −1 ·bar −1 ) and efficiency (99.7 ± 0.3%) for n -hexane/water mixtures, as well as excellent photodegradation efficiency (>99%) for methylene blue (MB). Remarkably, the optimized membrane exhibits remarkable scalability and stability, maintaining superior separation performance even after being rolled up 10 times with a curvature of 200 m −1 . This suggests that it has great potential for practical applications in complex environments.
研究领域:
材料科学
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环境工程
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膜技术
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电化学
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纳米材料
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DOI
高影响因子
CHEMICAL ENGINEERING RESEARCH & DESIGN
·
2019
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IF 3.073
Kai Wang,Yun Qin,Shuai Quan,Yingjie Zhang,Peng Wang,Heng Liang,Jun Ma,Xi Quan Cheng
With suitable pore size, narrow pore size distribution and charged surface, nanofiltration (NF) membranes show great potential in removing or recovering dyes from effluents of printing and dyeing industries. However, low permeance of commercial nanofiltration membranes hampers their widespread application. Herein, we design a kind of high permeance mixed matrix membranes through layer-by-layer (LbL) self-assembly of polyelectrolytes (PEs). The additional solvent pathways constructed by incorporation of UiO-66, a type of Zr-based metal organic frameworks (MOFs), accelerate the water passing through the membranes; the pure water permeance of UiO-66 incorporated PEs membrane (PEM/UiO-66) achieves at as high as 14.8 L m −2 h −1 bar −1 which is 160% higher than the pristine PEs membrane. Meanwhile, the membrane exhibits 96.3% rejection towards MgSO 4 with molecular weight cut off (MWCO) of 464.2 g mol −1 . The comprehensive separation performance of the mixed matrix membrane outperforms most of state-of-the-art NF membranes fabricated by LbL self-assembly to the best of our knowledge. Most interestingly, the mixed matrix membrane demonstrates solution flux as high as 102 L m −2 h −1 with 99.9% rejection of Congo Red under optimized operation conditions in 240 h continuous operation. Taken together, the UiO-66 incorporated NF membranes show strong promise in removing and recovery of dyes in industrial scale.
研究领域:
材料科学
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环境工程
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高影响因子
Journal of Materials Chemistry B
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2018
·Vol. 6
·期 47
·7908-7915
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IF 4.776
Chaoqun Liu,Hongshuang Qin,Lihua Kang,Zhaowei Chen,Huan Wang,Hao Qiu,Jinsong Ren,Xiaogang Qu
Photodynamic therapy (PDT) has been widely used as a noninvasive and moderate technique in precision cancer therapy by destroying cancer cells via light-induced reactive oxygen species (ROS). However, the overproduction of heat shock protein 70 (HSP70) induced by ROS will contribute to the cell survival under harsh conditions, finally leading to decreased PDT efficiency. To overcome this issue, herein, for the first time, we have prepared an HSP70 inhibitor (2-phenylethynesulfonamide (PES))-loaded graphitic carbon nitride nanosheet (GCNS) as a multifunctional nanoplatform (GCNS-PES) for enhanced PDT. By taking advantage of commendable PDT efficiency, strong blue fluorescence, satisfactory drug loading capacity and good water dispersity, the GCNS can simultaneously serve as a photosensitizer, an imaging agent and a drug carrier. Moreover, when the nanoplatform is restricted in the endo/lysosome vesicles through endocytosis, the GCNS can generate ROS effectively under visible light irradiation to promote the lipid peroxidation of endo/lysosomal membranes and accelerate the liberation of GCNS and PES into the cytoplasm. Finally, the tolerance of cancer cells to ROS is decreased by PES-induced HSP70 inactivation, and therefore the efficiency of PDT is significantly enhanced. As a result, GCNS-PES can serve as a promising therapeutic nanoplatform for photo-controlled cancer therapy.
研究领域:
生物医学工程
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癌症治疗
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纳米医学
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DOI
PubMed
高影响因子
JOURNAL OF POLYMER ENGINEERING
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2022
·Vol. 42
·期 9
·885-898
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IF 1.624
Yadi Zhang,Chengcong Wang,Lijuan Zhang,Jianghuan Shi,Haikuan Yuan,Jie Lu
Multiwall carbon nanotubes (MWCNTs) are often used to modify polymer membranes as additives, however, MWCNTs are easy to agglomerate and entangle in polymer matrix due to their own strong van der Waals force. MWCNTs were doubly modified by bonding octadecylamine (ODA) and SiO 2 through the respective amidation and esterification reactions to prepare SiO 2 -MWCNT-ODA nanocomposites. The amino groups on ODA were amidated with the carboxyl groups on MWCNT-COOH. Then the hydroxyl groups on SiO 2 were bonded to MWCNT-COOH through esterification to obtain SiO 2 -MWCNT-ODA nanocomposites. PES/SiO 2 -MWCNT-ODA composite ultrafiltration (UF) membrane was prepared by non-solvent induced phase separation (NIPS) method. SiO 2 -MWCNT-ODA nanocomposites and PES/SiO 2 -MWCNT-ODA membrane were characterized by FTIR, XRD, TGA, and SEM, etc. The results showed that PES/SiO 2 -MWCNT-ODA membrane had significantly improved permeability, rejection, and antifouling properties for comparison with PES membrane. The pure water flux of PES/Nano.2-0.5 reached 212.5 L m −2 h −1 , which was approximately 2.6 times than that of PES membrane, and the rejection of BSA protein for composite membrane was as high as 94.2%. PES/SiO 2 -MWCNT-ODA composite membrane had excellent antifouling performance and the flux recovery rate ( FRR ) of PES/Nano.2-0.5 membrane could still maintain at higher value of 84.82% after two cycles in the antifouling test.
研究领域:
材料科学
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环境工程
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膜技术
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高影响因子
Journal of Materials Chemistry B
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2017
·Vol. 5
·期 29
·5763-5773
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IF 4.543
Keke Wu,Wufeng Yang,Yanpeng Jiao,Changren Zhou
Electrospinning has been widely recognized as a facile and scalable method for fabricating fibrous materials, which could be used as adsorption materials because of their high surface area. Surface molecular imprinting based on adsorption materials has shown excellent adsorption performance, including large binding capacity, a fast adsorption rate and selective adsorption. In this study, electrospinning and surface molecular imprinting were used together to prepare a surface molecularly imprinted electrospun polyethersulfone (PES) fiber mat (PES@MIP). The mat was prepared by self-polymerization of dopamine (as a functional monomer) on the electrospun PES fiber mat surface in weak alkaline aqueous solution in the presence of a template, bilirubin. The results indicated that a polydopamine coating was formed on the PES fiber mat surface successfully, and the template bilirubin could be removed. The adsorption performance of PES@MIP was investigated in detail, showing a higher adsorption capacity (184.24 mg g−1), faster adsorption kinetics and a short adsorption equilibrium time of 2 h, as well as a good selectivity toward bilirubin with an imprinting factor (IF) of 1.4. In addition, the selectivity coefficient (α) of PES@MIP toward cholesterol and testosterone could be calculated to be 1.11 and 1.43. Also, both adsorption kinetic and isotherm models were used to analyze the adsorption process. Besides, the dynamic adsorption indicated that PES@MIP adsorbed much more bilirubin, and had a shorter equilibrium time of about 40 minutes for bilirubin removal. In addition, PES@MIP had a much lower hemolysis ratio and exhibited a little anticoagulant property compared to the original PES fiber mat. Therefore, this work provided a new strategy to build practical PES@MIP for bilirubin adsorption.
研究领域:
生物材料学
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医学工程
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DOI
PubMed
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
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2025
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IF 8.5
Xinlu Zhang,Zelin Liao,Xiaokun Wang,Xuehua Ruan,Hao Gong,Gaohong He,Xiujuan Zhang
Agarose, the natural hydrophilic polysaccharide with good biocompatibility, low immunogenicity and low cost which has been widely used in tissue engineering and regenerative medicine but not in biomedical equipment, was employed to modify the potential oxygenation membrane, the core component for blood oxygenation ex vivo in the artificial lung machine. The oxidized agarose was successfully coated onto the hydrophobic polydimethylsiloxane (PDMS) surface forming a hydrophilic layer via intermolecular chemical bonding as well as physical interactions based on characterization and analyses from SEM, HNMR, FTIR, XPS and water contact angle measurement. The agarose modification significantly improved the hemocompatibility, reducing protein adsorption by 50–60 % and hemolysis rate from ∼0.45 % to ∼0.2 %, elongating the plasma recalcification time and blood clotting time, as well as alleviating platelet adhesion, and the antibacterial performance of the membrane, which would reduce the contamination of the membrane thus prolonging the membrane service life as well as blood clotting, blood damage and blood fouling. Meanwhile, the CO 2 /O 2 gas selectivity was promoted to ∼9, an 64 % increase in comparison to that of unmodified membranes, which would significantly enhance the gas exchange efficiency of the oxygenation membrane. Moreover, the membrane modified with agarose exhibited long-term stability against platelet adhesion and blood leakage. This agarose modification strategy is simple yet effective, providing new ideas for oxygenation membrane synthesis and improvement.
研究领域:
生物医学工程
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材料科学
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DOI
PubMed
高影响因子
COLLOIDS AND SURFACES B-BIOINTERFACES
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2025
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IF 5.6
Yue Huang,Lunhao Zhi,Chong Cheng,Qiang Wei,Shudong Sun,Changsheng Zhao
In extracorporeal membrane oxygenation (ECMO) treatment, designing membrane with self-anticoagulant properties can solve problems resulting from the adverse effect of anticoagulants. In this study, 2,4,6-Triformylphloroglucinol (Tp) and 2,5-Diaminobenzenesulfonic acid (Pa-SO 3 H) were applied to grow a sulfonated COF film in situ on the polyethersulfone (PES) membrane. The introduction of sulfonic groups increased the hydrophilicity and electronegativity of the TpPa COF film, improved its anti-protein adhesion properties, maintained the normal morphology of blood cells, and endowed the COF film with antithrombotic properties. In the porcine blood circulation test, the duration to increase So 2 (O 2 saturation) from ∼75–95 % in TpPa-SO 3 H COF/PES membrane (M-TpPa-SO 3 H) was 70 min shorter than that in TpPa COF/PES membrane (M-TpPa). This preparation method is applicable to the preparation of not only flat membranes, but also hollow fiber membranes. These findings emphasize the potential of M-TpPa-SO 3 H in ECMO applications, providing superior antithrombotic property and CO 2 efflux potential.
研究领域:
生物医学工程
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材料科学
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血液学
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DOI
PubMed
高影响因子
Polymers
·
2024
·Vol. 16
·期 9
·1194
·
IF 4.7
Huyang Zhao,Ting He,Shuang Yao,Long Tao,Xinhai Zhang,Zhaohui Wang,Zhaoliang Cui,Rizhi Chen
The research used polyethersulfone (PES) as a membrane material, polyvinylpyrrolidone (PVP) k30 and polyethylene glycol 400 (PEG 400) as water-soluble additives, and dimethylacetamide (DMAc) as a solvent to prepare hollow-fiber ultrafiltration membranes through a nonsolvent-induced phase separation (NIPS) process. The hydrophilic nature of PVP-k30 and PEG caused them to accumulate on the membrane surface during phase separation. The morphology, chemical composition, surface charge, and pore size of the PES membranes were evaluated by SEM, FTIR, zeta potential, and dextran filtration experiments. The paper also investigated how different spinning solution compositions affected membrane morphology and performance. The separation efficiency of membranes with four different morphologies was tested in single-protein and double-protein mixed solutions. The protein separation effectiveness of the membrane was studied through molecular weight cutoff, zeta potential, and static protein adsorption tests. In addition, the operating pressure and pH value were adjusted to improve ultrafiltration process conditions. The PES membrane with an intact sponge-like structure showed the highest separation factor of 11, making it a prime candidate membrane for the separation of bovine serum albumin (BSA) and lysozyme (LYS). The membrane had a minimal static protein adsorption capacity of 48 mg/cm2and had excellent anti-fouling properties. When pH = 4, the BSA retention rate was 93% and the LYS retention rate was 23%. Furthermore, it exhibited excellent stability over a pH range of 1–13, confirming its suitability for protein separation applications.
研究领域:
生物工程
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材料科学
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DOI
PubMed
高影响因子
COLLOIDS AND SURFACES B-BIOINTERFACES
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2022
·
IF 5.999
Qianyu Wei,Shuman Feng,Zezhen Zhang,Lulu Liu,Lili Wu
A high protein retention polyethersulfone (PES) membrane was prepared by nonsolvent-induced phase separation and surface coating , which exhibited enhanced hemocompatibility and antioxidant stress performance. The cross-linked network was constructed by tannic acid (TA) and alpha-lipoic acid (α-LA) on the surface of the membrane, which controlled the pores to a reasonable size. The enrichment of heparin-like groups on the membrane surface, implemented by “hydrophobic interaction” and “click reaction”, confers anticoagulant properties; the presence of a large number of phenolic hydroxyl groups from TA and the introduction of α-LA allows the modified membranes to intervene in oxidative stress . The hemocompatibility characterizations included plasma recalcification time (PRT), activated partial thromboplastin time (APTT), prothrombin time (PT), thrombin time (TT) and hemolysis rate (HR). Additionally, the DPPH ABTS radical scavenging capacity was tested to evaluate the antioxidant performance. The results show that the modified membrane presents an outstanding protein retention rate (99.3%) along with permeability. In addition, the PRT is prolonged to 341.7 s, and the DPPH• scavenging ability reaches 0.74 µmol•cm -2 . The membranes can be easily prepared and present excellent comprehensive performance. This work provides a simple and facile strategy for the fabrication of hemodialysis membranes with controllable pore sizes.
研究领域:
生物材料
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医学工程
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膜科学
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产品关联
DOI
PubMed
高影响因子
JOURNAL OF MEMBRANE SCIENCE
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2020
·
IF 7.183
Jianxiu Wang,Ziyuan Liu,Ming Qiu,Chunju He
Natural heparin macromolecule has been widely used to improve the hemocompatibility of biomaterials. However, heparin can cause spontaneous bleeding in some patients, which is troublesome for clinical applications. Fortunately, analogous heparin polymers have shown promise to replace heparin. Here a new class of composite polyethersulfone (PES) membranes were constructed, which offered tunable permeability together with excellent hemocompatibility via incorporating heparin-mimicking semi-interpenetrating polymer. The polyurethane macromer was synthesized as an effective cross-linker to incorporate functional polyacrylic acid and poly-2-acrylanmido-2-methylpropanesulfonic acid segments into PES solution through in-situ cross-linking polymerization. Then the heparin-mimicking semi-interpenetrating composite PES membranes were fabricated from the resulting casting solution via alkali-induced phase separation technique. The resulting composite membranes showed excellent inhibition of protein adsorption , suppression of platelet adhesion, reduction of hemolysis ratio and prolongation of clotting times, while displayed high hydrophilicity, permeability and clearance to urea, creatinine and lysozyme. Interestingly, the composite membranes also exhibited excellent mechanical properties due to the synergistic effect of polyurethane composition and in-situ cross-linking copolymerization . To further demonstrate the applicability and effectiveness of this method, a composite PES hollow fiber with excellent ultrafiltration and mechanical properties was also fabricated. This straightforward and facile method is constructed as an ideal candidate to suppress blood clotting for a range of blood purification membrane-related applications.
研究领域:
生物材料
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生物医学工程
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膜科学
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DOI
高影响因子
危险品化学品经营许可证（带存储）