JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY
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2026
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IF 4.4
Kaihuai Duan,Tao Yang,Zhongyou Xu,Yijie Sun,Huiyun Hu,Hu Yang,Zhenliang Xu
Self-supporting and degradable (Zn-MOF/SA/CNF) acts as multifunctional photoactive membrane. • Zn-MOF acts as a porous skeleton to enhance flux, SA as a binder, and CNF as a photo-Fenton catalyst. • Membrane shows 96–98% rejection of dye, 80% rejection of tetracycline and a flux of 50–60 L‧m −2 ‧h −1 ‧bar −1 . • Membrane shows antibacterial property, photo-Fenton induced flux recovery and acid-triggered regeneration. In this study, self-supporting multifunctional photoactive membranes with a sandwich structure were prepared via a green route using eco-friendly materials for water treatment. The Zn-BDC synthesized at 25 °C was employed to construct a strippable skeleton with high flux. Sodium alginate (SA) acted as both a binder and cavity filler to repair defects and enhance tensile properties. Meanwhile, C₃N₄-Fe₂O₃ (CNF) was synthesized and applied as a photo-Fenton catalyst. The results showed that both the membrane with SA on the top (MCS) and the membrane with SA in the middle (MSC) achieved over 98% rejection toward Congo red, Alcian blue, and nickel(II) phthalocyanine-tetrasulfonic acid tetrasodium salt, with a flux ranging from 50 to 70 L·m −2 ·h −1 ·bar −1 . While the MSC membrane displayed better photocleaning performance and mechanical flexibility than the MCS membrane. Its flux could be restored via the photo-Fenton reaction. Moreover, the MSC membrane also attained over 80% rejection of tetracycline with the assistance of the photo-Fenton reaction. Furthermore, the membrane showed over 95% dye rejection in ethanol and exhibited favorable antibacterial performance. In addition, the membrane could be dissolved in a citric acid solution, which offers a convenient strategy for membrane disposal or recycling. Collectively, this work provides a green and sustainable membrane candidate for water treatment applications. Download: Download high-res image (129KB) Download: Download full-size image
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DOI
高影响因子
DESALINATION
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2026
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IF 9.9
Hui Wang,Heyao Lu,Kaiqi Chen,Guanbing Zhou,Yihui Yuan,Ning Wang
Efficient adsorption and recoverable removal of uranium from aqueous media are crucial for resource utilization and environmental risk mitigation. However, conventional adsorbents often suffer from poor structural stability, limited reusability, and difficulties in deployment and recovery, which hinder practical applications. Herein, a robust macroporous ternary composite gel bead (PEI/SA-XLS) was fabricated from sodium alginate (SA), polyethyleneimine (PEI), and synthetic hectorite-type clay (laponite XLS) via synergistic polyelectrolyte complexation, supramolecular crosslinking, and freeze-drying. SA and PEI formed a 3D network through electrostatic interactions, while XLS nanosheets reinforced the framework through hydrogen bonding between surface silanol groups and amino/hydroxyl groups. Freeze-drying generated macropores (~100 μm), thereby significantly enhancing mass transfer and facilitating uranyl diffusion into the bead interior. Mechanistically, negatively charged XLS surfaces promoted electrostatic enrichment of UO 2 2+ , while silanol, amino, and carboxyl groups provided cooperative binding sites for efficient uranyl capture. The maximum adsorption capacity ( q m ) was ~2707 mg·g −1 (Langmuir). A removal efficiency of ~98% was achieved at 15.1 mg·L −1 ( V = 100 mL), and ~ 93% efficiency was maintained after ten adsorption-desorption cycles. These results highlight that macroporous transport channels and mechanically robust pore walls play a dominant role in adsorption efficiency and cycling stability for macroscopic adsorbents.
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高影响因子
MOLECULES
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2025
·Vol. 30
·期 7
·1631
·
IF 4.6
Shuochao You,Shan Zhang,Yahao Geng,Tianhao Wu,Guiyong Xiao
Rapid functional soft tissue restoration has shown considerable promise as a framework for stability and coordination in the human body. Inspired by the anisotropic arrangement of structures with soft and hard phases in biological tissues, such as tendon, cartilage, and ligament, many methods have been used to fabricate composite hydrogels with appropriate mechanical properties. The development of a high-strength hydrogel with strong bioactivity remains a key barrier to replace soft tissues with comparable synthetic structures. In this study, a highly dispersed hydroxyapatite nanofiber (HANF) reinforced polyvinyl alcohol-sodium alginate (PVA/SA) composite hydrogel is prepared for soft tissue replacement. The effect of the addition of HANF on the microstructure and properties of composite hydrogel is also investigated. The results show that the PVA/SA hydrogel, after the incorporation of HANF, combines well with the PVA/SA hydrogel (HANF@PVA/SA). SEM morphologies show that dispersed HANF can enter the holes of the three-dimensional structure of the composite hydrogel. Additionally, the addition of HANF can enhance the compressive strength of the PVA/SA composite hydrogel from 4.66 MPa to 7.72 MPa. At the same time, the HANF@PVA/SA hydrogel maintains the same excellent hydrophilicity as the original PVA/SA hydrogel. Finally, cytotoxicity and live/dead cell staining tests also confirmed its excellent biocompatibility, demonstrating its tremendous potential for use in soft tissue repair.
研究领域:
材料科学
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生物医学工程
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组织工程
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DOI
PubMed
高影响因子
DESALINATION
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2024
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IF 8.3
Ting Shu,Yuliang Zhang,Xiahui Liu,Zhuo Liu,Ying Qin,Fei Wang,Xueting Chang,Dongsheng Wang,Lihua Dong,Xiaobo Chen,Xijia Yin,Zecheng Qian
Solar interfacial evaporation technology is an effective and sustainable method for seawater desalination. It is crucial to achieve high photothermal conversion efficiency, rapid evaporation rate, and long-term stability. In this study, a vertically aligned porous aerogel evaporator is prepared using sodium alginate as the substrate material and graphene oxide (GO) and polypyrrole (PPy) as the photothermal materials through a directional freezing technology. The polypyrrole@graphene oxide-sodium alginate evaporator exhibits a high solar photothermal conversion efficiency as high as 98.6 % and an evaporation rate of up to 4.66 kg·m −2 ·h −1 under 1 sun. During the 144-hour desalination, the evaporator transports brine for evaporation in the daytime and removes salt residue from the evaporator surface at night. It has demonstrated a self-cleaning behavior and restored its desalination stability. Thus, this aerogel evaporator with a high evaporation rate and stable salt resistance shows great potential for practical applications in solar thermal conversion and seawater desalination.
研究领域:
材料科学
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环境科学
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能源科学
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高影响因子
BIOSENSORS & BIOELECTRONICS
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2024
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IF 10.7
Yi Chen,Hengyi Chen,Xiaohui Chen,Yufang Zhang,Wei Tu,Jiaxi Mo,Shanshan Tian,Chenyu Sun,Xiaoqin Meng,Zhizeng Wang,Jichun Yang,Yang Luo
Accurate intracellular visualization of human telomerase RNA (hTR) is imperative for early diagnosis and treatment monitoring of hepatocellular carcinoma (HCC). While isothermal amplification-based DNA cascade strategies are promising, challenges persist in achieving great intake efficiency of detection probes within tumor cells and enhancing intracellular reaction efficiency. This study introduces a SA@Comb-HCR nanosystem , a highly effective approach for in situ hTR detection in HCC cells. Sodium alginate-coated liposomes ensures efficient nanoprobe delivery, which are then combined with proximity effect-inspired signal amplification . The coating of sodium alginate facilitates receptor-mediated endocytosis , prevents serum protein adhesion, and mitigates cationic liposome cytotoxicity. The designed Comb-like consolidated hairpin probe enhances the concentration of the local reactant, resulting in cascade amplification upon hTR activation. This technique achieves precision detection of intracellularly overexpressed hTR in HCC cells with a remarkable detection limit of 0.7 pM. This approach holds great promise for advancing targeted and sensitive early clinical diagnosis of HCC.
研究领域:
分子生物学
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肿瘤学
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生物医学工程
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PubMed
高影响因子
JOURNAL OF MATERIALS SCIENCE
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2024
·Vol. 59
·期 5
·1968-1988
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IF 3.5
Li Xiangyu,Ma Zhenfang,Wang Lili,Li Shuokang,Duan Yinhe,Wu Minghua
The composite films with flexible and high electromagnetic-shielding (EMI) performance have been attracting more and more attention. Herein, using MXene as an interlayer and carbon nanotube/sodium alginate (CNT/SA) as a core layer, a flexible and high EMI MXene@CNT/SA@MXene (MCS) film with a sandwich structure was successfully prepared via alternating vacuum filtration. The optimal MCS film was obtained with a MXene dosage of 15 mg, a CNT/SA dosage of 6 mg and a CNT:SA mass ratio of 6:4. The thickness of the MCS film had a linear relation with the MXene and CNT/SA dosages. The best MCS film was 12 μm thick and exhibited an EMI total electromagnetic wave efficiency ( SE T ) of 61.3 dB, SSE / t of 2.34 × 10 5 dB cm 2 g −1 and conductivity of 1.74 × 10 5 S m −1 . The breaking strength, breaking elongation and toughness of MCS film increased by 24.3%, 16.7%, and 40.0% in comparison with pure MXene film, and by 40.3%, 40.0%, and 100% in comparison with MXene/CNT/SA blend film, respectively.
研究领域:
材料科学
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电磁学
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高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
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2024
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IF 8.1
Hao Deng,Yanling Wu,Leyi Li,Xiaojia jiang,Peng Wang,Kui Fang,Jun Li,Derek Hao,Huayue Zhu,Qi Wang,Qiang Li
To tackle the issues of low adsorption capacity, poor regeneration efficiency, and limited recoverability in wastewater treatment adsorbents, we innovatively developed a low−cost Fe(III)−SA gel ball aerogel (FA) through a simple chemical crosslinking method. FA aerogel exhibits exceptional adsorption performance for a wide range of antibiotics, including norfloxacin (NOR), ciprofloxacin (CIP), and tetracycline hydrochloride (TC), showcasing its broad applicability. Remarkably, FA achieved a maximum NOR adsorption capacity of 338.4 mg/g (Langmuir isotherm model, pH 7.0, 298 K, m/V=0.1 g/L). Furthermore, under the synergistic effect of photocatalysis, FA demonstrated a breakthrough by removing 97 % of NOR (30 mg/L, 50 mL) within just 150 min. Notably, FA displayed innovative regeneration capabilities, successfully completing 10 continuous and stable NOR removal cycles without loss of performance. The DFT calculations alongside experimental evidence were employed to elucidate the NOR degradation pathway, while electron density distribution and Fukui function analysis confirming the proposed degradation pathways through HPLC−MS results. Moreover, plant stress and zone of inhibition tests verified that the degradation intermediates were significantly less toxic, ensuring the safety of the regeneration process. This research introduces an innovative approach for designing superior adsorbents and provides critical insights into efficient and sustainable adsorbent regeneration.
研究领域:
环境科学
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材料科学
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化学工程
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高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
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2024
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IF 7.7
Xinxin Fan,Yu Lu,Yujun Xie,Xiaodong Yan,Wanyu Fan,Yuji Ishii,Boyang Yu,Renshi Li
Anemarrhena asphodeloides Bge. (AAB), a traditional medicinal herb, has a long history of delaying the aging process. Yet, the anti-aging effects of its polysaccharides have not been thoroughly investigated. This study marks the first exploration of the anti-aging activity of Anemarrhena asphodeloides Bge. polysaccharides (AABP). The MW of AABP-1a was determined to be 210.062 kDa, with a composition consisting predominantly of glucose and mannose in a molar ratio of approximately 4:1. The backbone of AABP-1a was mainly composed of →4)-2Ac-β-Man(1→ and →4)-β-Glc(1→ and a small amount of branched →4,6)-β-Glc(1→ and →3,4)-β-Glc(1→, the branching part was composed of →6)-β-Glc(1→ and t-α-Glc(1→. AABP-1a has antioxidant capacity and can improve cell cycle arrest mediated by senescence markers such as p53 , p21 , p16 and SASP, and reduce the accumulation of damaged DNA. In addition, it could reduce the activity of SA- β -Gal in zebrafish, prolong the lifespan of C. elegans and reduce the expression of lipofuscin. This study found a glucomannan and demonstrated its anti-aging activity in various aging models. These results provide a theoretical basis for further study of the anti-aging effect of AAB.
研究领域:
中药学
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生物化学
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衰老研究
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DOI
PubMed
高影响因子
JOURNAL OF ALLOYS AND COMPOUNDS
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2025
·
IF 6.3
Dongju Liu,Kunlan Diao,Daohai Zhang,Yupeng Hu,Zhi Lei,Teng Zhou,Kaixiang Zou,Shuhao Qin
With the popularity of wireless communication technology, the problem of electromagnetic radiation and interference is highlighted, and the development of efficient electromagnetic shielding materials has become a research priority. In this study, firstly, polyvinyl alcohol/sodium alginate (PVA/SA) hydrogels were prepared by physical cross-linking method, and further, iron-based metal-organic frameworks (Fe-MOFs) were prepared by solvothermal synthesis method, and with reduced graphene oxide (RGO) as a conductive filler, and γ-aminopropyltriethoxysilane (KH550) as a cross-linking agent, were prepared by chemical cross-linking method. Modified polyvinyl alcohol/sodium alginate/iron based metal organic framework/reduced graphene oxide (PVA/SA/Fe-MOF/RGO-KH550) composite hydrogel. The results show that the composite hydrogel has a compressive stress of 20.13 MPa, a compressive strain of 83.28 %, and an electromagnetic shielding efficiency of 39.98 dB at a thickness of 3 mm, which reaches the mid-range and high-end level, and it can be applied to industrial control, small and medium-sized data centres, automotive electronics, and general medical devices with medium-high requirements. The excellent performance of the hydrogel comes from the conductive properties and interfacial polarisation effect of RGO, the dielectric loss of Fe-MOF, which work in synergy, and KH550 optimises the interfacial bonding between the filler and the substrate to form a denser crosslinked structure, which strengthens the mechanical properties and electromagnetic shielding effect. The hydrogel preparation process is simple and low-cost, which provides a reference for the design of high-performance electromagnetic shieldingmaterials and an effective solution to the problem of electromagnetic interference.
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高影响因子
Pharmaceutics
·
2022
·Vol. 14
·期 7
·1337
·
IF 6.525
Lijun Song,Jiabo Chen,Yuxuan Feng,Yujing Zhou,Feng Li,Guiqin Dai,Yue Yuan,Haosen Yi,Yupei Qian,Siyan Yang,Yang Chen,Wenchang Zhao
Genistein (Gen), a kind of natural isoflavone drug monomer with poor water solubility and low oral absorption, was incorporated into oral nanoparticles with a new mesoporous carrier material, NH2-MCM-41, which was synthesized by copolycondensation. When the ratio of Gen to NH2-MCM-41 was 1:0.5, the maximum adsorption capacity of Gen was 13.15%, the maximum drug loading was 12.65%, and the particle size of the whole core–shell structure was in the range of 370 nm–390 nm. The particles were characterized by a Malvern particle size scanning machine, XRD, Fourier transform infrared spectroscopy, scanning electron microscopy, and nitrogen adsorption and desorption. Finally, Gen-NH2-MCM-41 was encapsulated by sodium alginate (SA), and the chimerism of this material, denoted as GEN-NH2[email protected], was investigated. In vitro release experiments showed that, after 5 h in artificial colon fluid (pH = 8.0), the cumulative release reached 99.56%. In addition, its anti-rotavirus (RV) effect showed that the maximum inhibition rate was 62.24% at a concentration of 30 μM in RV-infected Caco-2 cells, and it significantly reduced the diarrhea rate and diarrhea index in an RV-infected-neonatal mice model at a dose of 0.3 mg/g, which was better than the results of Gen. Ultimately, Gen-NH2[email protected]was successfully prepared, which solves the problems of low solubility and poor absorption and provides an experimental basis for the application of Gen in the clinical treatment of RV infection.Keywords:genistein;mesoporous silica;Caco-2 cells;sodium alginate;targeted release
研究领域:
药学
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纳米技术
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病毒学
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药物递送系统
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DOI
PubMed
高影响因子
NANO
·
2021
·
IF 1.556
Wenlong Li,Weiwei Zhang,Weihao Jin,Longbao Zhu,Wanzhen Li,Ping Song,Yugui Tao,Fei Ge
Design of high-performance drug delivery system is necessary to improve the anticancer ability of 5-fluorouracil (5-FU). In this work, we developed a pH-responsive 5-FU loaded and sodium alginate (SA) modified mesoporous silica nanoparticles (MSNs) drug delivery system (5-FU@MSN-SA). After 5-FU was loaded into the pores, MSNs were successfully functionalized with amino groups and then capped by sodium alginate. Compared to acidic conditions, the drug release rate in the neutral environment was quite low. Moreover, detailed investigations confirmed that 5-FU@MSN-SA can easily be up-taken by cancer cells and proved the high cytotoxicity to 4T1 cells. The calculated IC 5 0 values for 5-FU and 5-FU@MSN-SA were 34.67 μ g/mL and 54.95 μ g/mL, respectively. These results indicated that 5-FU@MSNs-SA can be a promising nanoplatform in cancer therapy.
研究领域:
药剂学
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肿瘤学
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纳米医学
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DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2026
·
IF 12.5
Shuyue Long,Ying Huang,Zhihao Lin,Sujuan Yan,Xiaoyi Luo,Xia Ren,Xianjun Fu,Zhengao Wang,Wuyi Zhou
Emulsion electrospinning co-delivered nano cuttlebone and quercetin in fibers. • Nano cuttlebone enabled rapid hemostasis and > 96% antibacterial activity. • Nanofiber membrane afforded antioxidant activity and promoted hemostasis. • The membrane suppressed biofilms and coordinated staged infected-wound repair. Persistent bleeding, bacterial colonization, oxidative stress, and prolonged inflammation are major barriers to the repair of infected wounds. An ideal dressing should rapidly control bleeding and bacterial contamination, while regulating oxidative and inflammatory microenvironments to support tissue regeneration. Herein, a multifunctional PCL-PVA/SA@nano CB composite nanofiber membrane was developed by emulsion electrospinning for infected-wound therapy. In this system, polycaprolactone (PCL) provided structural stability, while the hydrophilic polyvinyl alcohol/sodium alginate (PVA/SA) phase improves wettability, water absorption, breathability, and bioactive-agent delivery. Nano Cuttlebone acted as a calcium-rich component for rapid hemostasis and antibacterial activity, whereas quercetin contributes antioxidant and anti-inflammatory functions. In vitro , the optimized membrane achieved antibacterial efficiencies of 96.72% against S. aureus and 96.58% against E. coli , inhibited S. aureus biofilm formation, scavenged DPPH radicals, and promoted L929 fibroblast proliferation and migration. In vivo , the membrane accelerated hemostasis in a mouse liver bleeding model and promoted S. aureus -infected full-thickness wound healing, reaching 98.9% closure on day 14. The nanofiber membrane also reduced bacterial burden, regulated macrophage polarization, suppressed CD86/TNF-α, enhanced CD206/IL-10, and promoted collagen deposition and re-epithelialization. This study provides a promising multifunctional electrospun dressing for complex infected wounds.
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高影响因子
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