ANALYTICA CHIMICA ACTA
·
2026
·
IF 6.1
Juliana Gaithan Kauno,Haili Wei,Shiyu Xia,Wenping Gao,Zohaib Saddique,Fenghua Li,Fengxia Wu,Guobao Xu,Hsien-Yi Hsu,Ziaur Rehman,Yu Tian,Wenxin Niu
The phosphate ion (PO 4 3− ) is essential for growth, especially skeletal development. However, high PO 4 3− levels can signal health problems, such as hyperphosphatemia, which indicates chronic kidney disease due to reduced filtration, leading to serum phosphate buildup. Therefore, there is a pressing need for an accurate and convenient method for PO 4 3− analysis. Considering the significance of its detection, several techniques based on nanozymes have been employed, and among them, fluorometry is one of the most robust and efficient techniques. In terms of nanozymes, current developments suffer from low catalytic activity and non-specific inhibition. To address these issues, we present a solid-solution strategy for synthesizing Ce–Zr–O nanozymes with a defect-rich polycrystalline structure, providing a highly specific and efficient sensing platform. The approach is simple and cost-effective, yielding Ce–Zr–O nanozymes with excellent uniformity, controllable size, and morphology. Incorporating Zr 4+ into the CeO 2 lattice induces abundant oxygen vacancies and structural heterogeneity, which synergistically enhance the phosphatase-like activity by enhancing Lewis acid catalysis and aiding the nucleophilic hydrolysis of 4-methylumbelliferyl phosphate (4-MUP). Notably, phosphate (PO 4 3− ) ions specifically bind to Zr sites, altering their electronic environments and attenuating catalytic performance. In exploiting this selective inhibition, we developed a fluorometric phosphate assay with high selectivity and sensitivity. The Ce–Zr–O nanozymes detected phosphate with a limit of detection (LOD) of 0.061 nM, allowing precise measurement of phosphate in urine. This study presents a generalizable defect-engineering method for Ce–Zr–O nanozymes, creating a reliable platform for interference-resistant biosensing in biological fluids.
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产品关联
DOI
PubMed
高影响因子
Advanced Energy Materials
·
2026
·
IF 26
Xianghui Shi,Zhihao Zhang,Liuxin Xu,Zhe Wang,Qianjiang Mao,Yue Jiang,Xiaoxin Yang,Zihao Ma,Dan Cheng,Wenkun Jiang,Mingzhen Hu,Kebin Zhou
Globally, the proton exchange membrane water electrolyzers (PEMWEs) already account for approximately 30% of the hydrogen market and are undergoing rapid expansion. However, the commercially used iridium-based anodic oxygen evolution reaction (OER) catalysts in PEMWEs still suffer from notably poor reactivity. At present, the oxide pathway mechanism (OPM) is an important route to achieve both high activity and durability in OER. Nevertheless, the performance of conventional Ir-based crystalline OER catalysts following the OPM pathway remains far below their theoretical limit, which is significantly hindered by two intrinsic limitations. First, their rigid lattice structures prevent the shortening of metal-metal distances, which is essential to facilitate the rate-determining O * ─O * dimerization. Second, the repulsion between O * adsorbates during OER inevitably weakens the metal = O * bond and undermines the overall oxygen evolution efficiency. Herein, we report that an amorphous IrMO x catalyst elegantly overcomes the limitations of the OPM pathway by virtue of its dynamic surface structure and strong oxophilicity of M. The dynamic surface structure promotes O * ─O * coupling, while the oxophilic nature of M compensates for the inherent weakening of the metal = O * bond during OER. Because of that, the catalyst exhibits outstanding OER performance, along with excellent catalytic durability over 1200 h’ PEM testing.
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产品关联
DOI
高影响因子
MEDICINAL CHEMISTRY RESEARCH
·
2017
·Vol. 26
·期 3
·672-679
·
IF 1.277
Liu Zhenbao,Wang Xiaohong,Zhang Hang,Zhang Shanshan,Li Yiqian,Liu Yanfei,Peng Dongming
Berberine owns multiple pharmacological activities, especially anti-inflammatory activity. To enhance the anti-inflammatory therapeutic efficiency of berberine, a series of novel 9- O -substituted berberine derivatives ( 5a – 5d ) were synthesized and their anti-inflammatory activities were evaluated. 13 C-NMR, 1 H-NMR, IR and high resolution mass spectrum (HRMS) results indicated that these derivatives were successfully synthesized. The xylene-induced inflammatory mice model demonstrated that these derivatives showed dose-dependent inhibition of ear inflammatory swelling. Comparing to berberine, ibuprofen and naproxen-modified berberine derivatives enhanced anti-inflammatory activities, while aspirin and nicotinic acid-modified berberine derivatives showed lower anti-inflammatory effects at the same dosages. This could be attributed to the enhanced inhibition of secretion of cytokines, including interleukin-6 and tumor necrosis factor-α, by ibuprofen and naproxen berberine derivatives, while aspirin and nicotinic acid berberine derivatives showed lower inhibition of tumor necrosis factor-α than berberine. These results suggest that ibuprofen and naproxen-modified berberine derivatives are promising new anti-inflammatory drug candidates.
研究领域:
药物化学
·
炎症研究
·
生物合成
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DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2022
·
IF 16.744
Kang An,Siran Zhang,Hong Wang,Ningyan Li,Ziyang Zhang,Yuan Liu
Direct hydrogenation of CO 2 into ethanol has been considered as an up-and-coming way to achieve CO 2 utilization. Ethanol can be generated by reverse water gas shift as well as CO hydrogenation over Co-based catalysts, where the regulation of Co 0 − Co δ+ is critical. Herein, we designed a supported Co-based catalyst doped with gallium, which was derived from Co-Al-O spinel precursor to facilitate synergistic catalyzing for CO 2 -to-ethanol transformation. The selectivity of ethanol reached 20.1 % in a continuous flow fixed micro-reactor over reduced CoGa 1.0 Al 1.0 O 4 /SiO 2 catalyst at 270 °C and 3.0 MPa. Results of characterization show that the existence of the strong interaction between Ga oxide and cobalt induced the configuration of Co 0 − Co δ+ active pairs, which promotes the process of ethanol synthesis by coupling the dissociation (CH x *)/non-dissociation (CO*) of the intermediates. The strategy by tuning the interaction between cobalt and gallium and/or aluminum oxide brings an avenue to tailor Co 0 − Co δ+ active pairs for the hydrogenation of CO and CO 2 .
研究领域:
催化化学
·
能源化学
·
材料化学
·
环境化学
·
工业催化
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DOI
高影响因子
JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY
·
2021
·
IF 8.067
Fengnian Zhang,Fuhao Cheng,Chufei Cheng,Meng Guo,Yufeng Liu,Yang Miao,Feng Gao,Xiaomin Wang
Abatract A series of compositionally complex fluorite oxides (CCFOs) were prepared by ball milling the mixture of ZrO 2 , HfO 2 , Y 2 O 3 , La 2 O 3 , and Pr 6 O 11 followed by conventional solid-state sintering. Both XRD and TG-DSC results demonstrated that single-phase (Zr 0.2 Hf 0.2 Pr 0.2 Y 0.2 La 0.2 )O 2-δ was formed at 1400 °C. Elements in bulk ceramic were uniformly distributed without evident accumulation according to SEM-EDS pictures. TEM results revealed that polycrystalline ceramic powder was assignable to cubic Fm-3m fluorite structure. The electrical conductivity ( σ ) was measured via EIS technology and activation energy ( E a ) of CCFOs was calculated in Arrhenius plots. In the temperature range of 300-750 °C, CCFOs preserved the same conduction mechanism and (Zr 0.1667 Hf 0.1667 Pr 0.1667 Y 0.25 La 0.25 )O 2-δ possessed higher σ and lower E a than other high entropy fluorite oxides which is related to the incorporation of Pr element or the connection of cation-V o complex.
研究领域:
材料科学
·
无机非金属材料
·
固体离子学
·
功能陶瓷
·
能源材料
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DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2013
·
IF 3.473
Manhong Liu,Qiang Bai,Hailian Xiao,Yanyan Liu,Jun Zhao,William W. Yu
Colloidal platinum–ruthenium bimetallic nanoparticles with 2.3 nm were synthesized in solution and then immobilized on tin dioxide powder to make a supported nanocatalyst (Pt–Ru/SnO 2 ). The immobilized bimetallic nanoparticles had the same size and size distribution as the solution dispersed ones. Selective hydrogenation of o -chloronitrobenzene to o -chloroaniline was performed over the as-prepared Pt–Ru/SnO 2 nanocatalyst without using any solvent; 99.5% selectivity to o -chloroaniline at ∼100% conversion was achieved.
研究领域:
催化化学
·
纳米材料
·
有机合成
·
绿色化学
·
应用化学
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DOI
高影响因子
ACS Applied Energy Materials
·
2022
·
IF 6.959
Shuaiqi Han,Jingjing Jiang,Xinge Liu,Bingyan Li,Kangjie Zhang,Shasha Hao,Shaotang Yu,Weibo Yan,Hao Xin
The state-of-the-art copper indium gallium selenide Cu(In,Ga)Se2 (CIGS) thin-film solar cells are fabricated based on vacuum methods and use cadmium sulfide as the buffer layer. Considering the cost-effective production and environmental safety, fabrication of a CIGS absorber via the solution process and using a cadmium-free buffer layer is desirable. Here, we report engineering of a chemical-bath-deposited zinc sulfoxide Zn(S,O) buffer layer for solution-processed CIGS solar cells. Our results show that optimization of the deposition time and annealing process of the Zn(S,O) film to avoid cracking is critical to obtain a dense and uniform Zn(S,O) buffer layer. Benefited from the large band gap of Zn(S,O) and light-soaking-induced device performance improvement, a champion CIGS solar cell with a power conversion efficiency of 12.0% (without antireflection coating) has been achieved. This is the first time that the Zn(S,O) buffer layer has been applied to a solution-processed CIGS absorber and achieves highly efficient CIGS solar cells. The effect of light-soaking on the heterojunction property and the stability of device performance are discussed.
研究领域:
光伏技术
·
材料科学
·
薄膜太阳能电池
·
可再生能源
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DOI
高影响因子
ACS Applied Materials & Interfaces
·
2018
·
IF 8.097
Huachao Tao,Shaolin Du,Fei Zhang,Lingyun Xiong,Yaqiong Zhang,Hui Ma,Xuelin Yang
Carbon materials with high initial Coulombic efficiency (ICE) and specific capacity in lithium-ion batteries are highly attractive. Herein, P-doped carbon has been prepared, and as an anode for lithium-ion batteries, it exhibits remarkably improved ICE and reversible capacity. P atoms are apt for the formation of the P–O bond in carbon with oxygen-containing groups. The doped P content strongly depends on the O content in carbon. The high-doped P content of 5.79 at. % can be obtained through changing the O content in carbon. Carbon with high contents of P and O displays high ICE and capacity as an anode for lithium-ion batteries. The P–O bond in carbon changes the morphology and composition of the solid electrolyte interface (SEI) layer and is beneficial to the formation of a thin and dense SEI layer. The P–O bond in carbon prevents the permeation and decomposition of solvated PF6– in the interior of the electrode during cycling, resulting in the improved ICE, reversible capacity, and rate capability. As an anode for lithium-ion batteries, the ICE can be improved to 70.9% for carbon with the P–O bond from 36.9% for carbon without the P–O bond. Carbon with the P–O bond displays high specific capacities of 566 mA h g–1 after 100 cycles at 0.1 A g–1 and 432 mA h g–1 after 1000 cycles at 1 A g–1. This design offers a simple and efficient method to improve the ICE and reversible capacity of hard carbon.
研究领域:
材料科学
·
储能
·
电化学
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DOI
高影响因子
ENVIRONMENTAL SCIENCE & TECHNOLOGY
·
2023
·
IF 11.4
Guoquan Liu,Pengfei Wang,He Zhang,Yi Li,Sihui Zhan
Improving the reaction rate of each step is significant for accelerating the multistep reaction of NO reduction by H2. However, simultaneously enhancing the activation of different gaseous reactants using single-atom catalysts remains a challenge to maximize the activity. Herein, we propose a strategy that utilizes titanium-vacancy-regulated electronic properties of single atoms and defective support (Pt1/d-TiO2) to facilitate electron transfer from edge-share O atoms (OTi) to adjacent Pt single atoms. This leads to the formation of low-valence Pt and unsaturated-charge OTi sites, which causes the catalytic reaction to follow a synergistic mechanism. Specifically, experimental and theoretical analyses demonstrate that low-valence Pt sites finely tune the adsorption of H2 molecules, consequently lowering the dissociation energy from 0.15 to as low as 0.01 eV. Moreover, using quasi-in situ spectroscopy, we clearly observe NO molecules being adsorbed on interfacial oxygen sites of a defective support. Then, the bond energy of the N–O bond is weakened through an electron acceptance–donation mechanism between unsaturated-charge OTi sites and NO, thereby facilitating NO activation. The designed single-atom catalysts with synergistic sites exhibit unmatched activity at low temperatures (above 90% NOx conversion at 100 °C), along with higher turnover frequency value (0.74 s–1) and superior stability, making them potentially suitable for industrial applications.
研究领域:
催化化学
·
环境化学
·
材料科学
·
表面科学
·
纳米技术
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DOI
高影响因子
DALTON TRANSACTIONS
·
2022
·Vol. 51
·期 10
·4097-4103
·
IF 4.569
Zhikang Chen,Kewang Zhang,Bei Zhang,Jun Zhang
A new borate, Na2SrB16O26, was synthesized by the high-temperature solution method. It exhibits complicated interpenetrating 3D B–O frameworks composed of the functional building block (FBB) [B8O16]. The UV-vis-NIR diffuse reflectance spectroscopy shows that it has a deep-ultraviolet (DUV) cutoff edge (<200 nm). The relationship between the structures and optical properties was uncovered by theoretical calculations. By the first-principles calculation, the birefringence is estimated to be 0.07 at 1064 nm. The response electron distribution anisotropy (REDA) analysis indicates that the [BO3] units contribute mainly to the generation of the moderate birefringence.
研究领域:
材料科学
·
无机化学
·
光学材料
·
非线性光学
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DOI
高影响因子
JOURNAL OF ORGANOMETALLIC CHEMISTRY
·
2021
·
IF 2.369
Ke Cao,Ji Wu,Cai-Yan Zhang,Li-Fang Ding,Junxiao Yang
A palladium catalyzed intramolecular amination of B(7)-H for synthesis of o -carborane fused isoquinolinones has been developed. Kinds of o -carborane fused isoquinolinones decorated with active groups have been synthesized with good to excellent yields. A plausible mechanism involving palladium catalyzed electrophilic B-H activation/amination was proposed.
研究领域:
有机化学
·
催化化学
·
硼化学
·
药物化学
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DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2019
·
IF 8.355
Peng Liu,Qiang Ru,Peiming Zheng,Zhenglu Shi,Yang Liu,Chiquan Su,Xianhua Hou,Shichen Su,Francis Chi-Chung Ling
Currently, there are three primary obstacles to the development of high-performance supercapacitors: low electron conductivity of the electrode materials used, their poor ion-transport efficiency, and the unstable structure. Herein, to overcome these obstacles, one-dimensional Zn 2 GeO 4 (ZGO) rods were grown within a carbon nanotube (CNT) framework using a simple one-step hydrothermal strategy for use as a supercapacitor electrode material. The crosslinked ZGO/CNT-O hybrid exhibits a large contact surface area with respect to electrolytes, contains abundant electrochemical active sites, and has short ion-diffusion paths. Further, the flexible CNTs act as superior connective bridges, promoting electron transmission and resulting in a stable structure. The ZGO/CNT-O hybrid showed a specific capacitance of 164.25 F/g at a current density of 1 A/g. It also displayed superior cycling durability, exhibiting a specific capacity of 120 F/g at a current density of 10 A/g, even after 200,000 cycles. A simple crosslinking strategy and prolonged cycle durability are demonstrated, which endow ZGO/CNT-O with potential for use in supercapacitor electrodes.
研究领域:
材料科学
·
储能
·
纳米技术
·
电化学
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DOI
高影响因子
危险品化学品经营许可证（带存储）