Bioactive Materials
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2026
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IF 23.6
Rui Yuan,Sa Du,Jieyao Cheng,Zeyu Ma,Ruoxi Wang,Xiue Yan,Yonghui Huang,Yuwei Wu,Lei Tao
Harmful blue rays (HBRs, 400-450 nm) originating from the sun and numerous electronic devices are similar to ultraviolet rays (UVRs) and can induce skin photoaging. Ordinary sunscreens exhibit poor HBR-blocking capability, and traditional anti-HBR materials are unsuitable for skin protection. Herein, we develop a polymer-metal complex that can be applied to the skin to effectively block HBRs. Hydroxyquinoline is introduced into the polymer backbone via the Biginelli reaction. This polymer (P) exhibits strong coordination with Zn(II). The resulting P-Zn(II) complex undergoes a spectral redshift through metal-ligand orbital transitions, enabling effective shielding of both UVRs and HBRs. The P-Zn(II) complex protects fibroblasts from HBR-induced cell death, oxidative stress, and cellular aging by preventing HBR-triggered dysregulation of multiple photoaging-related signaling pathways and genes. In mouse experiments, the P-Zn(II) complex exhibits minimal skin irritation and low hepatic and renal toxicity. It can be applied to the skin in a manner similar to sunscreens and effectively prevents HBR-induced skin damage, which fills the gap in HBR protection left by current commercial products. This study highlights the potential of polymer-metal ion complexes as advanced photoprotective materials and provides valuable insights into the development of anti-HBR biomaterials.
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TALANTA
·
2026
·
IF 6.7
Xiao Ma,Junjie Wang,Xin Chen,Jingcheng Li,Jiaqi Xue,Yufan Hou,Shihao Zhao,Jingxiang Zhao,Xiaomi Meng,Huajun Chen,Fang Wang,Fangya Guo,Jian Sun,Dan Zhao
Oxidase-like nanozymes use dissolved O 2 as the terminal electron acceptor and do not require exogenous H 2 O 2 , offering methodological advantages; however, conventional “one-pot carbonization” often causes concurrent carbonization and active-site formation, making the coordination environment difficult to control. Here, a sequential “pre-coordinate-polymerize-pyrolyze” site-engineering route was developed. On carbon black, OPD-Fe 3+ pre-coordination and in situ oxidative polymerization were carried out, followed by thermal treatment and purification, by which Fe–N moieties were immobilized within the shell region of the material to afford highly dispersed Fe–N x moieties predominantly featuring Fe–N 4 -like coordination (Fe–N 4 @CB d ). Multiscale characterization (XRD/XPS/XANES/EXAFS) consistently showed that iron resided predominantly in a first coordination sphere dominated by Fe–N (coordination number CN ≈ 3.7; R ≈ 2.01 Å), with no resolvable Fe–Fe scattering and only minor, non-dominant Fe-containing phases. ROS-trapping and time-dependent EPR measurements further confirmed continuous O 2 activation with the generation of O 2 • - , •OH, and 1 O 2 in the Fe–N 4 @CB d /O 2 system. DFT calculations additionally supported Fe–N 4 -like Fe–N x sites as the most plausible dominant active structures for O 2 activation. Under a unified TMB/O 2 system, steady-state enzyme kinetics exhibited outstanding performance, with V max = 351 nmol L −1 s −1 and K m = 0.56 mM, which are competitive among reports using the same substrate/readout. An H 2 O 2 -free colorimetric platform for alkaline phosphatase (ALP) was constructed on this material, achieving a low limit of detection and good linearity; acceptable accuracy and precision were verified by standard additions in diluted serum. This sequential strategy predefines the Fe–N neighborhood and topology at the precursor stage, reduces uncertainty in site formation, and avoids metal-organic framework (MOF)/hard-template/ionic-liquid multi-step procedures, thereby providing a strong basis for reproducible Fe–N 4 -like/Fe–N x oxidase-like nanozyme preparation and streamlined, robust bioanalysis.
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COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
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2026
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IF 5.4
Xiaojing Chen,Fan Ye,Jianan Song,Shengye You,Xiaobi Fang
Injectable HGL2 hydrogel forms in situ for infected diabetic oral ulcers. • Polycatechin nanoparticles provide broad ROS scavenging to relieve oxidative stress. • Quaternized chitosan confers rapid antibacterial action against oral pathogens. • HGL2 accelerates angiogenesis and mucosal regeneration, achieving near closure. Diabetes-associated oral ulcers represent a difficult-to-treat mucosal wound type characterized by persistent inflammation and delayed tissue regeneration. In such lesions, excessive oxidative stress, bacterial colonization, and insufficient angiogenesis synergistically compromise healing outcomes and limit the effectiveness of conventional topical therapies. However, a single therapeutic platform that can concurrently mitigate infection and redox imbalance while providing structural support for mucosal remodeling remains largely unavailable. Here, we show an injectable and in situ forming polysaccharide hydrogel patch (HGL2) composed of polycatechin nanoparticles, oxidized β-glucan, and quaternized chitosan for targeted ulcer care. Our results demonstrate that this system exhibits potent antimicrobial efficacy against Staphylococcus aureus and Escherichia coli alongside superior radical scavenging capabilities to reshape the hostile wound microenvironment. Furthermore, the multifunctional network enhances cellular survival under oxidative stress and promotes robust angiogenesis to achieve rapid lesion closure in diabetic rodent models. Collectively, our hydrogel provides a clinically deployable strategy for synchronizing antimicrobial action and tissue reconstruction in the management of complex diabetic mucosal wounds. Download: Download high-res image (236KB) Download: Download full-size image
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BIORESOURCE TECHNOLOGY
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2026
·
IF 8.2
Chen-Xi Li,Qian Ren,Feng Peng,Ming-Fei Li
A synergistic catalyst was prepared on lignin-derived carbon via two-step strategy. • The catalyst achieved an exceptional lactic acid yield of 58.91% from xylan. • The catalyst demonstrated remarkable versatility across diverse biomass-derived sugars. • High recyclability was realized attributable to Co–N 4 /Zn AC configuration. Hydrothermal catalysis offers a sustainable route for lignocellulosic valorization, while conventional catalysts often necessitate demanding conditions and efficient hemicellulose conversion remains challenging. Herein, a nitrogen-doped lignin-derived carbon-based synergistic catalyst, embedding cobalt single-atom and zinc atomic clusters (Co SAC -Zn AC @LCN), was constructed via a pre-coordination and pyrolysis two-step coupled strategy for one-pot conversion of hemicellulose to lactic acid (LaA). Characterizations revealed well-dispersed and spatially proximate Co single-atom and Zn clusters anchored on stacked two-dimensional carbon–nitrogen nanosheets. The strong synergistic interaction between Co single-atom and Zn clusters enhanced Lewis acidity and further facilitated C C bond cleavage and intermediate rearrangement. Co SAC -Zn AC @LCN exhibited a mesoporous structure with a high surface area (140.61 m 2 /g) and elevated carbon defects, promoting reactant diffusion and adsorption. Under optimized conditions (240 °C, 1 h), the catalyst achieved 58.9% LaA yield and 113.7 h −1 TOF from xylan and maintained over 42% yield across various biomass-derived sugars, demonstrating its remarkable catalytic performance and universality. Owing to the stable Co–N 4 /Zn AC configuration, it retained over 56% LaA yield after six cycles. This work provides a general strategy to design atomic-scale synergistic catalysts from biomass carbon for efficient lignocellulosic conversion to high-value chemicals. A nitrogen-doped carbon catalyst embedded with Co single-atom and Zn atomic clusters was constructed leveraging a lignin-derived framework. The strong synergistic interaction between Co single-atom and Zn clusters enhanced Lewis acidity and facilitated the efficiently conversion of hemicellulose to lactic acid. Owing to the stable Co–N 4 /Zn AC configuration, it retains excellent cycling stability. Download: Download high-res image (145KB) Download: Download full-size image
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INORGANIC CHEMISTRY COMMUNICATIONS
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2026
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IF 5.9
Le Wang,Jinwen Zhao,Siqing Zhang,Yanqin Zhu,Qinhong Yin
The hazards of bisphenol A (BPA) represent a significant public health concern, and developing accurate methods for its detection in water is of great importance for both human health and environmental protection. To address this, we have developed a dual-quantum dots fluorescent (FL) probe for highly efficient BPA recognition. This probe is fabricated by embedding iron‑manganese quantum dots (Fe Mn QDs) and copper‑zinc quantum dots (Cu Zn QDs) into a molecularly imprinted polymer matrix using a one-pot synthesis method. The constructed Fe Mn QDs/Cu-Zn QDs@MIPs sensor integrates dual FL emissions at 575 nm (Fe Mn QDs) and 525 nm (Cu Zn QDs) for specific recognition of BPA. Upon interaction with BPA, the sensor exhibits enhanced yellow fluorescence from Fe Mn QDs while the blue-green fluorescence of Cu Zn QDs is quenched. The fluorescence intensity ratio (F575 nm/F525 nm) demonstrates a single-exponential function relationship with BPA concentration. The employment of a dual-signal transduction mechanism enables the sensor to exhibit exceptional selectivity and ultrahigh sensitivity, with a wide linear detection range of 2.283–228.3 μg/L and a low detection limit (LOD) of 1.142 μg/L. To demonstrate its practical applicability, the sensor was employed for the quantitative detection of BPA in commercially bottled water, achieving satisfactory recoveries ranging from 96.0% to 104.4%. This work presents a practical and innovative approach for developing a ratiometric sensing system with dual fluorescence signals integrated with a smartphone-based visual detection platform for monitoring trace-level BPA.
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INTERNATIONAL JOURNAL OF HYDROGEN ENERGY
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2026
·
IF 9.2
Xingxing Jiang,Yu Li,Xiao Du,Yang Zhao,Donghong Duan,Zhonglin Zhang,Xiaogang Hao
Developing stable and efficient non-precious metal electrocatalysts for oxygen evolution reaction (OER) is crucial for advancing water electrolysis and sustainable energy systems. Herein, we exploit a trimetallic MoNiFe metal-organic framework (MOF) with high surface area, porosity, synergistic active sites derived from metallic components, and charge-tunable organic ligands. Via a solvothermal synthesis followed by gas-phase phosphorization, the MoNiFe-MOF/NF precursor is transformed into Mo–NiFeP@NC/NF. Benefiting from structural and compositional advantages, Mo–NiFeP@NC/NF exhibits superior OER activity and stability in alkaline media compared to commercial RuO 2 /NF. The catalyst achieves current densities of 50 and 100 mA cm −2 at low overpotentials of 271 and 303 mV, respectively, along with a reduced Tafel slope, indicating favorable reaction kinetics. Moreover, the electrode shows negligible activity degradation after continuous operation at 50 mA cm −2 for 61 h. This work provides a new insight into the rational construction of efficient and stable non-precious metal OER catalysts based on metal doping and MOF-derived strategies.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
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2026
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IF 8.7
Lanlan Dong,Reyihanguli Alimu,Zhongwang Li,Xin Zheng,Patiguli Aihemaiti,Wurikaixi Aiyiti,Cijun Shuai,Houfeng Jiang
Hyaluronic acid-xanthan gum-NAGA composite hydrogels were made using polyphenols. • Tea polyphenols optimizes mechanical, pH-response, and antioxidant properties. • NHXTP significantly upregulates IL-10 and suppresses IL-1β and TNF-α expression. • NHXTP accelerates wound closure in a rat full-thickness skin defect model. • NHXTP promotes organized tissue regeneration in full-thickness skin defect rats. Functional hydrogel dressings that combine excellent mechanical properties, biological activity, and environmental responsiveness are urgently needed in wound management. Polyphenols have antioxidant, anti-inflammatory, and wound-healing properties. However, their impact on structural fidelity and long-term stability in 3D-printed hydrogel systems remains poorly understood. Additionally, previous studies lack systematic investigation into swelling behavior within the dynamic pH environment of wound healing. This study aims to develop a multifunctional wound dressing capable of adapting to dynamic pH changes within wounds through systematic modification with polyphenols. Functionalized hyaluronic acid (HA)-xanthan gum (XG)-N-acryloylglycine (NAGA) composite hydrogels (NHX) were prepared using a polyphenol (tea polyphenols (TP), tannic acid (TA), and gallic acid (GA) immersion modification strategy. The effects of polyphenol type, concentration, and immersion time on the material properties were systematically investigated. Incorporating TPs synergistically optimized mechanical properties (337% tensile strain, 0.45 MPa stress), pH-responsive swelling behavior (up to 160% swelling at pH 9), and antioxidant activity (ABTS scavenging >99%) of the hydrogel by forming dynamic hydrogen bonds within the polymer network. In vitro anti-inflammatory experiments confirmed that the NHXTP hydrogel significantly upregulates IL-10, and suppresses IL-1β and TNF-α expression. In a rat full-thickness skin defect model, NHXTP dressings markedly accelerated wound closure (98.1% healing rate at 14 days) and promoted organized tissue regeneration. These findings contribute to the development of next-generation high-performance wound dressings.
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JOURNAL OF ALLOYS AND COMPOUNDS
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2026
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IF 6.7
Hao Liu,Yaji Huang,Huikang Song,Tianhang Tang,Hao Shi,Lang Kai,Chenlu Yang
A novel pathway for the co-disposal of municipal solid waste incineration fly ash (MFA) and bottom slag (BS) with waste glass (WG) was proposed. Combined melting experiments and theoretical calculation were employed, which revealed the structural evolution of the CaO-Fe₂O₃-SiO₂ system and the underlying mechanisms of heavy metal immobilization. It was demonstrated that stable glassy products were obtained within a CaO/(Fe₂O₃+SiO₂) mass ratio ( M C / ( SF ) ) range of 0.13~0.41. The leaching concentrations of heavy metals in these vitrified products were suppressed to the relevant regulatory standards. With an increasing M C / ( SF ) , the glass network became more depolymerized, as evidenced by a higher population of low-connectivity Qⁿ units in the structure. However, under Fe₂O₃-enriched system, the Fe coordination shifted from solely tetrahedral [FeO₄] towards a mixed tetrahedral/octahedral environment. Moreover, Pb and Cd were incorporated into the glass matrix via interstitial doping. The depolymerized network dominated by CaO favored the Pb enrichment. Cd tended to be stabilized in the Fe-rich structure, facilitated by the formation of highly localized Cd-O bonds. This study elucidated the coupling effects of oxide composition on glass structure and heavy metal immobilization behavior, providing a fundamental theoretical basis for understanding and optimizing the vitrification process for solid waste treatment.
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CHEMICAL ENGINEERING JOURNAL
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2026
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IF 12.5
Zhengyu Ding,Yalong Liu,Jiali Yu,Zheyao Xia,Jun Zhang,Kainan Guo,Jinke Guo,Binjie Xin,Shouzhi Yan
Biomimetic “flower-on-fiber” Janus membranes were engineered. • Achieved >99% emulsion separation and 97.4% TCH degradation under visible light. • Proposed Z-scheme supported by EPR/DFT boosts visible-light charge separation. • Asymmetric wettability enables unidirectional oil transport and “Janus boat” application. • Synergistic physical/photocatalytic mechanism confers 99.99% antibacterial rate. The remediation of complex industrial wastewater—characterized by the coexistence of emulsified oils, soluble organic micropollutants, and pathogenic bacteria—necessitates a paradigm shift from passive filtration to active, multifunctional interface engineering. To address this, a novel biomimetic “flower-on-fiber” Janus membrane was engineered via a sequential electrospinning and spray-deposition strategy. The membrane features a rationally designed asymmetric architecture, integrating a hydrophobic Z -scheme photocatalytic top-layer (BiOBr/ZnO/TiO 2 @PVDF) with a hydrophilic substrate (PAN@PEG). Molecular Dynamics (MD) simulations were used as qualitative support to examine the water/BiOBr interfacial behavior, indicating that water molecules tend to remain aggregated rather than spread on the BiOBr lattice. Consequently, the membrane achieved high-efficiency separation (>99%) of surfactant-stabilized water-in-oil emulsions with a superior flux of 2120 ± 119 L m −2 h −1 . Beyond physical separation, the constructed heterojunction promoted visible-light absorption and suppressed charge recombination. This endowed the membrane with exceptional “active” defense capabilities: a 97.4% degradation efficiency for tetracycline hydrochloride (TCH) and a 99.99% antibacterial rate against E. coli via a synergistic “physical puncture-photocatalytic oxidation” dual-mode mechanism. This work demonstrates a proof-of-concept Janus membrane platform that couples structural biomimicry with Z -scheme heterojunction engineering to integrate water-in-oil emulsion separation, visible-light-driven tetracycline degradation, and antibacterial activity against E. coli .
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Small Science
·
2026
·Vol. 6
·期 4
·e202500570
·
IF 7
Rongyan He,Qiuyu Cao,Wenhui Yan,Shuting Xiao,Xiaoying Liang,Yuxiu Ye,Dongting Zhangsun,Sulan Luo
Effective wound management is crucial for improved outcomes through timely, personalized therapies. Current dressing-based treatments lack dynamic regulation and microenvironment modulation, leading to suboptimal healing. Integrating electrical stimulation therapy with electro-controlled drug delivery promotes skin generation, ensures precise dosing, and accelerates healing. Flexible electronic patches are ideal platforms for these synergistic therapies but face challenges: rigid post-manufacture shapes and sizes limit adaptability to diverse wound geometries, and substrate materials struggle to meet both wound-healing and electronic requirements. This study develops a tailorable, transferable flexible electronic patch with a hexagonal modular design, enabling shape/size customization while maintaining electrical continuity. The water-transfer printing (WTP) technique is used to conveniently transfer conductive chondroitin sulfate (CS) hydrogel (as electrodes and drug reservoirs) and silver circuits onto clinical dressings. This method endows clinical dressings with functionality of electro-controlled drug release and electrical stimulation, simultaneously addressing substrate performance limitations of flexible electronic patches. The patch demonstrates uniform electrical signal transmission, precise electro-responsive drug control in CS hydrogels, and adaptability to wounds of different geometries. It retains electrostimulation and electro-controlled drug delivery performance after cutting, significantly promoting wound healing. This study provides a potential approach to support the advancement of flexible electronics research and clinical translation.
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COLORATION TECHNOLOGY
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2026
·
IF 2.6
Lin Cai,Zhaoyong Gao,Benzhi Ju,Wei Ma,Bingtao Tang,Shufen Zhang
Disperse dyes are virtually insoluble in water, necessitating the addition of substantial quantities of dispersants and extensive grinding to produce commercially viable dyes suitable for polyester fabric dyeing. In this study, a series of 2,4-bis(4-sulfonylanilino)-1,3,5-triazin-6-yl starch ethers (BSATS) with varying molecular weights were prepared through non-directive sulfonation of acid-degraded starch in an aqueous medium for application as disperse dye dispersants. The dispersing performance and underlying mechanisms of these dispersants were analysed. The results showed that the BSATS series of dispersants exhibited superior dispersing ability for disperse dyes. Compared with the commercial dispersant NNO (dye filtration time 68 s after treatment, dispersibility rating C, particle size change 68% after high temperature treatment), the dispersants BSATS 3–7 with molecular weights ranging from 13.2 × 10 4 to 21.0 × 10 4 g-mol −1 showed superior dispersibility (dispersibility rating B) and thermal stability (particle size change only 12% after high temperature treatment). Additionally, the BSATS dispersants were employed to disperse C.I. Disperse Orange 30 primary dyes, yielding uniformly dispersed dye liquors for polyester fabric dyeing. In terms of dyeing performance, the dye suspension containing BSATS dispersant achieved a dye uptake of 90% and colour fastness grades of 4–5. This study presents a methodology for the preparation of starch-based high-performance dye dispersants, thereby expanding the efficient utilisation of biomass starch in the printing and dyeing industry.
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ACS Sensors
·
2026
·
IF 10.9
Peng Xu,Yanlei Guo,Xin Lv,Shuting Wei,Dan Yang,Renquan Guan,Yuxin Wang,Yingmin Teng,Aiceng Li,Huaqiao Tan,Zhongling Lang,Zheng Lou,Lili Wang,Zhao Zhao
The necessity for high-efficiency, low-power room-temperature (RT) ammonia (NH3) sensors is particularly acute in environmental monitoring, industrial safety, and medical diagnostics. However, conventional chemiresistive sensors frequently require elevated temperatures to initiate reactions, leading to high energy consumption and potential safety risks. Inspired by plant photosynthesis, this paper successfully designs a ternary S-scheme heterojunction for a photo-activated RT NH3 sensor. The design effectively mimics the efficient charge transfer process in photosynthesis, thereby significantly promoting the separation and migration of photogenerated carriers and enhancing the sensing performance. Experimental results demonstrate exceptional performance under illumination: a high response value of 1679% (representing a 20-fold improvement over the dark state), rapid response and recovery times of 2.1 s and 1.9 s, respectively, along with outstanding selectivity, excellent stability, and a detection limit as low as 17 ppb. This work demonstrates a novel, efficient RT photo-activated NH3 sensor and provides innovative insights into designing biomimetic, smart gas-sensing materials and devices.
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危险品化学品经营许可证（带存储）