KINETICS AND CATALYSIS
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2013
·Vol. 54
·期 6
·716-723
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IF 0.543
Zeng Minfeng,Sun Xudong,Qi Chenze,Zhang Xian-Man
A novel and environmentally friendly heterogeneous catalyst has been prepared through the wet impregnation of copper(I) species onto the highly porous chitosan microspheres (CuI/PCMS). This novel CuI/PCMS heterogeneous catalyst with no additional ligands is much better than CuI homogeneous catalysts when applied in Heck reactions. Moreover, the reaction conditions are much milder than those for the similar copper catalysts mediated cross-coupling reactions reported in the literature. PCMS has been demonstrated not only the excellent solid support, but also have many unique functional groups to chelate the copper (I) species to enhance its catalytic activity.
研究领域:
催化化学
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有机合成
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材料化学
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环境友好化学
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功能高分子材料
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DENTAL MATERIALS
·
2026
·
IF 6.3
Zhiwen Liu,Danni Wang,Leiqing Zhang,Yuan Xie,Taoyu Chen,He Wen,Wenjia Chen,Baiping Fu,Ruikang Tang,Hongqiang Cheng,Zhe Wang
Mineralization of reconstituted type I collagen and demineralized dentin exhibited a biphasic concentration-dependent response to Sr²⁺. • Higher intrafibrillar mineralization was observed at 0.1–0.5 mM Sr²⁺, whereas lower levels were observed at 0.75–1 mM Sr²⁺. • Dentin mineralization showed a similar trend consistent with the collagen observations. • A Sr²⁺ concentration-dependent hypothesis is proposed for ion-regulated biomineralization. Objectives To investigate the concentration-dependent effects of strontium on the mineralization of reconstituted type I collagen and demineralized dentin remineralization. Methods Sr²⁺ at varying concentrations (0, 0.1, 0.25, 0.5, 0.75, 1 mM) was incorporated into polyacrylic acid-stabilized amorphous calcium phosphate (PAA-ACP) mineralization solutions. The mineralization solutions with 1 mM Sr²⁺ were characterized by scanning electron microscopy (SEM), transmission electron microscopy (TEM), Fourier-transform infrared spectroscopy (FTIR), and X-ray diffraction (XRD). Cytocompatibility was assessed using the CCK-8 assay. Reconstituted type I collagen and demineralized dentin models were employed to explore mineralization differences; high-resolution TEM (HRTEM) and selected area electron diffraction (SAED) were applied to investigate the underlying biphasic mineralization mechanism of Sr²⁺. Results In the reconstituted type I collagen model, early crystalline mineralization was detected at 12 h in the 0.25 mM group, while 0.5 mM Sr²⁺ induced more ordered apatite crystal alignment along the collagen long axis. The observed lattice expansion ( d -spacings of 0.35–0.37 nm and 0.29 nm) was consistent with the formation of Sr-containing apatite-like mineral. At ≥ 0.75 mM Sr²⁺, the minerals deposited preferentially on the fibril surface replaced intrafibrillar mineralization. In the demineralized dentin model, a consistent biphasic concentration-dependent pattern was observed: 0.1–0.5 mM Sr²⁺ was associated with increased density of the remineralized layer and enhanced dentinal tubule occlusion, the enlarged lattice spacing ( d -spacings of 0.35 nm) was consistent with that observed in the reconstituted type I collagen model. In contrast, 0.75–1 mM Sr²⁺ was associated with reduced remineralization and intratubular mineral filling. Both the collagen and dentin models suggested the biphasic effect of strontium on biomimetic mineralization. Significance Sr²⁺ shows a biphasic concentration-dependent response on collagen mineralization and dentin remineralization. These findings provide preliminary concentration-response information for the rational design of Sr-containing biomimetic materials. Download: Download high-res image (196KB) Download: Download full-size image
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Results in Chemistry
·
2026
·
IF 5.8
Xianping Luo,Sihao Yu,Hepeng Zhou,Yongbing Zhang,Jin-Ru Feng
Porous biochar derived from discarded corn stalks was developed as a regenerable adsorbent for treating Tl-containing wastewater. The Tl adsorption capacity of Fe–Mn–Y doped biochar (FMYBC) was significantly enhanced compared to unmodified biochar. The IPD model accurately described Tl(I) adsorption on FMYBC, indicating that intraparticle diffusion is a key controlling step. Removal efficiency remained largely stable over a broad initial pH range of 3–13. Doping with rare earth elements markedly improved the adsorption performance of Fe Mn modified biochar under acidic conditions. However, the presence of coexisting ions (Na + , Mg 2+ , Ca 2+ ) reduced FMYBC's Tl + adsorption capacity. After two adsorption–desorption cycles, MFYBC retained 86.4% of its initial Tl removal capacity, demonstrating good stability and regeneration potential. Based on XPS and FTIR analyses, the primary Tl(I) removal mechanisms include ion exchange, surface complexation, and oxidation.
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ADVANCED MATERIALS
·
2026
·
IF 29.1
Haoyang Guan,Luxuan Men,Zhuoer Cai,Yiping Du,Qingsong Hu,Taifeng Lin,Feng Luo,Zhengguang Yan,Jiawen Xiao
Copper(I)-based halides are promising for X-ray detection due to their excellent scintillation efficiency and solution processability. However, the structure–property relationship remains elusive, and their practical viability for X-ray imaging is largely unverified. In this work, we employ a bond‑mode control strategy to synthesize two compounds from the same amine precursor: ionic (4‑ATHP) 2 CuI 3 and coordinative (4‑ATHP) 4 Cu 4 I 4 (4-ATHP = 4-Aminotetrahydropyran), providing a model system to study their photophysics and underlying mechanism. (4‑ATHP) 2 CuI 3 adopts a unique 1D crystal structure with alternating arrangement of Cu 2 I 6 dimers, which shows excitation‑dependent dual emissions. Experimental and calculation results indicate that the dual emissions originate from the Cu 2 I 6 dimer with a different Cu─Cu bond length. In contrast, the (4‑ATHP) 4 Cu 4 I 4 shows single emission centered at 635 nm, in which the organic component contributes to the excited state. The ionic (4‑ATHP) 2 CuI 3 achieves a much higher light yield (55 923 photons/MeV) than that of the coordinative counterpart (31 866 photons/MeV). Furthermore, a large‑area flexible film (15 × 20 cm 2 ) based on (4‑ATHP) 2 CuI 3 delivers a spatial resolution of 20 lp/mm. Critically, integrating this film into a CMOS imager demonstrates superior dynamic imaging without afterglow, outperforming the commercialized CsI: Tl screen. This study not only deciphers the bond‑mode‑dependent photophysics but also validates a commercial‑grade scintillator, paving the way for high‑performance X‑ray imaging materials.
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Advanced Healthcare Materials
·
2026
·
IF 11
Jinling Zheng,Yingying Ke,Dandan Meng,Marie Helene Delville,Shiwen Yu,Yiteng Huang,Xiaoyu Xu,Xu Zhang,Shayibai Shabiti,Na Liang,Yujue Wang,Fangjie Li,Hongfei Chen,Wenjun Li
Sono-photodynamic therapy (SPDT) offers a non-invasive, spatiotemporally precise approach to cancer treatment, but its effectiveness is still limited by poor tumor specificity and penetration. To address this, we developed a cascade-targeted type I/II sensitizer, Ce6-TPP-Phe-Tyr (CTPT), which integrates chlorin e6 (Ce6), triphenylphosphonium (TPP), and a phospho-peptide motif for precise tumor targeting and potent SPDT. Upon dephosphorylation by tumor-overexpressed alkaline phosphatase (ALP), CTPT undergoes enzyme-instructed self-assembly (EISA) into nanoparticles (CTPT NPs), promoting their accumulation and retention in tumors. The TPP cations then guide these nanoparticles to mitochondria, concentrating the therapeutic payload at this critical organelle for cellular energy metabolism. Subsequent ultrasound/laser irradiation further enhances tissue permeability and triggers the generation of both type I and type II reactive oxygen species (ROS), leading to potent oxidative damage. This integrated strategy of EISA and mitochondria-targeted SPDT achieved approximately 86% tumor regression in ALP-overexpressing xenografts. This strategy minimizes systemic toxicity and achieves potent tumor regression by cascade delivery of the therapeutic agent, thereby significantly enhancing the precision and efficacy of SPDT.
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BIOELECTROCHEMISTRY
·
2026
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IF 4.9
Huang Wei,Xu Yiwei,Guo Yaojie,Chen Dingyao,Ren Wenjie,Suo Zhiguang,He Baoshan
In this work, a novel electrochemical aptasensor was constructed for the sensitive detection of DON by integrating the synergistic effect between the catalytic signal enhancement of Cu-Pt NPs and Exo I-assisted cyclic amplification, with an MWCNTs-AuNPs modified electrode serving as the sensing platform. Cu-Pt NPs with outstanding peroxidase-like catalytic activity were synthesized and used as signal probes to catalyze the substrate, generating significantly enhanced electrochemical signals. Meanwhile, Exo I enabled target recycling via specific strand cleavage. The two amplification mechanisms synergistically amplify the detection signal by enhancing catalytic efficiency and increasing cycle numbers. MWCNTs-AuNPs possess both a high specific surface area and superior conductivity, facilitating efficient electron transfer and biomolecule immobilization. In the presence of DON, the Exo I mediated recycling reaction is triggered, which leads to a reduction in the amount of the immobilized Cu-Pt NPs signal probes on the aptasensor surface. Under optimal conditions, the proposed aptasensor demonstrated a detection range from 0.1 to 500 ng/mL, and a low detection limit of 0.06 ng/mL, along with high selectivity, reproducibility, and stability for DON detection. Furthermore, the proposed aptasensor achieved satisfactory recovery rates in real sample analysis, indicating its promising potential for practical applications.
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CHEMICAL ENGINEERING SCIENCE
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2026
·
IF 5.1
Huiyun Xia,Zeliang Wu,Kaixuan Fan,Lifang Song,Sen Huang,Meiqi Yang
In response to the problem of nitrogen oxide pollution in tunnel environments, this study successfully prepared I - doped Bi 2 O 2 CO 3 photocatalyst I-BOC through solid-phase grinding method. The introduction of I - leads to a notable reduction in the bandgap of BOC, while also enhancing the specific surface area and pore volume, thereby facilitating the effective separation of photogenerated carriers. When exposed to visible light, I-BOC demonstrates a peak degradation efficiency of 58% for NO, and experiments involving free radical capture indicate that ·O 2 – is the primary active species, and explore the impact of the tunnel environment on the degradation efficiency of the catalyst. Additionally, epoxy resin served as the substrate for film formation, and 1H, 1H, 2H, 2H-perfluorodecyltrimethoxysilane (PFDTES) was incorporated as a low surface energy additive. A superhydrophobic photocatalytic self-cleaning coating (FBIE) characterized by a micro-nano rough structure was created using a one-step spraying technique. This coating showcases outstanding superhydrophobic properties and water contact angle exceeding 150°, along with excellent mechanical durability and chemical stability, achieving a visible light degradation efficiency of up to 65% for NO, and outstanding physical and chemical self-cleaning ability. By exploring the catalytic effects of I-BOC and FBIE coatings under different humidity conditions, the synergistic mechanism of coating photocatalysis and self-cleaning is revealed, providing broad application prospects for coatings in tunnel air purification.
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Inorganic Chemistry Frontiers
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2026
·
IF 6.2
Jia-Wei Liu,Dan Li,Peng-Xu Lu,Tao-Xiao Wen,Yan-Ru Chen,Jian-Hua Jia,Ming-Liang Tong
Luminescent metal nanoclusters featuring near-infrared (NIR) emission hold promise for diverse applications. Although ligand engineering can modulate their NIR optical properties, separating the effects of single-ligand in dual-ligand systems remains challenging. In this study, we employed a controlled variable approach to prepare three structurally comparable silver-rich clusters-Ag11Cu3, Cu@Ag14-xCux, and Ag18. By maintaining a constant thiolate ligand and solely varying the phosphines, we elucidated the synergistic regulatory impacts of the ligands on the core configuration and excited-state dynamics. Structural and optical analyses reveal that the monodentate phosphine (TPP) stabilizes an Ag6@Ag5Cu3 core of the cluster Ag11Cu3, leading to NIR-I emission (720 nm) originating from mixed triplet state metal-centered and charge transfer transitions. In contrast, the bidentate phosphine (trans-dppe) facilitates the formation of a nested Ag6@Ag8@Ag4 core of the cluster Ag18, triggering NIR-II emission (1424 nm) associated with highly delocalized core-based excited states. Moreover, the spatial influence of the chiral bidentate phosphine ((S,S)-BDPP) can induce core-structural distortion, which promotes nonradiative decay and results in luminescence quenching of the cluster Cu@Ag14-xCux. This work clarifies the relation between the structure and luminescence properties of ligand-mediated metal clusters, offering valuable insights for the design of tailored NIR optical materials.
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Collagen and Leather
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2026
·Vol. 8
·期 1
·23
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IF 10.1
Wei Nannan,Zhang Yuchen,Huang Wenjie,Tian Xinyu,Yao Linyan,Xiao Jianxi
Ultraviolet (UV) irradiation is a major cause of photoaging, driving oxidative stress, inflammation, and extracellular matrix (ECM) degradation. Collagen is central to dermal integrity, yet animal-derived sources pose immunogenic and pathogen risks, while recombinant collagens reported to date often lack the stable triple-helical architecture required for bioactivity. Here, we present a triple-helical recombinant humanized type I collagen (THRCI) that combines native-like conformation with excellent biosafety and regenerative efficacy. THRCI supported fibroblast adhesion, proliferation, migration, and collagen synthesis, while suppressing intracellular reactive oxygen species and pro-inflammatory cytokines. In zebrafish, THRCI reduced oxidative stress and alleviated UV-induced caudal fin atrophy. In a murine model of acute UV photodamage, topical THRCI accelerated epidermal recovery, restored hydration and barrier function, increased dermal density, and promoted collagen fiber remodeling, while downregulating IL-6 , IL-1β , MMP-1 , and MMP-9 . Collectively, these findings indicate that THRCI exhibits effective photodamage-repair properties in our established models and represents a promising animal-free collagen biomaterial for skin regeneration. Graphical The alternative text for this image may have been generated using AI.
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CERAMICS INTERNATIONAL
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2026
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IF 6
Yutong Zhang,Guoquan Yang,Jieling Zhang
Tendon injuries are common in table tennis and remain difficult to repair because of oxidative stress and limited regenerative capacity. This study developed an electrospun PPDO-COL-I/ x %CeMnBG fiber membrane with potential applications in tendon repair. The membranes exhibited uniform, bead-free morphology, good flexibility, a tensile strength of 5.89 MPa, and an elongation at break of 80%. All groups maintained cell viability above 80% over 5 days, while PPDO-COL-I/1.5%CeMnBG showed the best cell performance, with 110% proliferation on day 5. This group also displayed excellent ROS-scavenging activity, achieving 60% DPPH, 40% SOD, and 60% ABTS clearance, together with reduced intracellular ROS and enhanced L929 migration. These results indicate that PPDO-COL-I/1.5%CeMnBG is a potential candidate for tendon regeneration by integrating structural support, bioactive ion release, and antioxidant protection.
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Materials Today Bio
·
2026
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IF 11
Zhipeng Li,Yaoyao Wu,Jialin Wu,Cheng Zhang,Xinsheng Cheng,Hongzhen Zhang,Shikai Wang
Ulcerative colitis (UC) is a chronic inflammatory bowel disease characterized clinically by recurrent abdominal pain and bloody diarrhea, for which there is currently a lack of curative therapeutic strategies. In recent years, neutrophil extracellular traps (NETs) have been identified as playing a key role in the pathogenesis of UC, emerging as a potential therapeutic target. Although deoxyribonuclease I (DNase I) can exert therapeutic effects by degrading the DNA backbone of NETs, its clinical application is limited by inherent drawbacks, including poor in vivo stability, low bioavailability, and inefficient penetration of biological barriers. Herein, this study constructed a biomimetic membrane-based nanodelivery system. Initially, zeolitic imidazolate framework-8 (ZIF-8) was used to encapsulate DNase I, forming ZD nanoparticles to enhance enzymatic stability. Subsequently, these nanoparticles were coated with bacterial outer membrane vesicles (BOMVs), yielding the final BVZD composite system, designed to improve targeting to inflammatory sites. The BVZD system exhibited suitable particle size, good biocompatibility, and a demonstrated ability to specifically accumulate in the inflamed intestinal regions of a UC model. Both in vitro and in vivo experiments confirmed that BVZD effectively degraded NETs, suppressed endoplasmic reticulum stress (ERS) by downregulating the expression of prostaglandin-endoperoxide synthase 2 (PTGS2), and promoted the repair of the intestinal epithelial barrier. These findings highlight the promising therapeutic potential of BVZD for the treatment of UC.
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Nanomaterials
·
2025
·Vol. 15
·期 12
·897
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IF 4.3
Haiwei Wu,Jiaming Zhang,Fangbo Zhao,Wei Fan,Song Yang,Jun Ma
In chlorination disinfection treatment, residual iodinated X-ray contrast media (ICMs) are the precursors to iodinated disinfection by-products (I-DBPs). This study employed CoFe2O4nanoparticle catalytic peracetic acid oxidation (CoFe2O4/PAA) to remove iopamidol (IPM) and control I-DBP formation. The experimental results demonstrated that over 90% of the IPM degradation was achieved in 40 min. The metastable intermediate (≡Co(II)-OO(O)CCH3), rather than the alkoxyl radicals, was identified as the dominant oxidation species (ROS). The electron transfer pathways between the metastable intermediate and IPM were oxygen-atom transfer and single-electron transfer. The monoiodoacetic acid formation potential (MIAAFP) was investigated. In ultraviolet-activated ClO−(UV/chlorine), a portion of I−generated through IPM dehalogenation underwent conversion to reactive iodine species (RIS), consequently elevating the MIAAFP. In CoFe2O4/PAA, the MIAAFP was less than 43% of that in UV/chlorine, which can be attributed to the complete conversion of I−into iodate IO3−without generating RIS. CoFe2O4/PAA is thus a promising treatment for removing ICMs and controlling I-DBP formation due to the efficient degradation of ICMs while avoiding the generation of RIS.
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