International Journal of Nanomedicine
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2012
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IF 3.13
Xiaowei Ma,Huan Wang,Shubin Jin,Yan Wu,Xing-Jie Liang
Background There is an urgent need to develop drug-loaded biocompatible nanoscale packages with improved therapeutic efficacy for effective clinical treatment. To address this need, a novel poly (2-hydroxyethyl methacrylate)-poly (lactide)-1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine [PHEMA-g-(PLA-DPPE)] copolymer was designed and synthesized to enable these nanoparticles to be pH responsive under pathological conditions.Methods The structural properties and thermal stability of the copolymer was measured and confirmed by Fourier transform infrared spectroscopy, nuclear magnetic resonance, and thermogravimetric analysis. In order to evaluate its feasibility as a drug carrier, paclitaxel-loaded PHEMA-g-(PLA-DPPE) nanoparticles were prepared using the emulsion-solvent evaporation method.Results The PHEMA-g-(PLA-DPPE) nanoparticles could be efficiently loaded with paclitaxel and controlled to release the drug gradually and effectively. In vitro release experiments demonstrated that drug release was faster at pH 5.0 than at pH 7.4. The anticancer activity of the PHEMA-g-(PLA-DPPE) nanoparticles was measured in breast cancer MCF-7 cells in vivo and in vitro. In comparison with the free drug, the paclitaxel-loaded PHEMA-g-(PLA-DPPE) nanoparticles could induce more significant tumor regression.Conclusion This study indicates that PHEMA-g-(PLA-DPPE) nanoparticles are promising carriers for hydrophobic drugs. This system can passively target cancer tissue and release drugs in a controllable manner, as determined by the pH value of the area in which the drug accumulates.
研究领域:
药剂学
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肿瘤学
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生物材料科学
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高影响因子
INORGANIC CHEMISTRY
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2018
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IF 4.7
Leyan Nian,Kui Wu,Guijie He,Zhihua Yang,Shilie Pan
In the exploration of new infrared nonlinear optical (IR NLO) materials, element substitution has been developed as an effective way to adjust the structural features and material performances. A series of new IR NLO materials have been discovered in the I–Ba–MIV–Q system (I = Li, Na, Cu, and Ag; MIV = Si, Ge, and Sn; Q = S and Se), and they undergo interesting structural transformation with different element substitution except Li analogues. Herein, we have successfully synthesized three selenides with different space groups (Ag2BaSiSe4: I4̅2m; Ag2BaGeSe4 and Ag2BaSnSe4: I222) in the above system and studied their properties through experimental and theoretical methods. Remarkably, the detailed analysis on the structural changes and properties comparison was also systematically investigated in the I–Ba–MIV–Q system and the results indicate that the distortion degrees of different IQ4 tetrahedra play the critical role to cause the structural transformation with the M or Q elements substitution. More importantly, we have also found that the structural changes have the close relationship with the distance d(I–I) between adjacent I cations in the I2BaSnSe4 system, which makes the four-membered rings formed by edge-sharing BaSe8 units change from the square to rhombus with the increase of d(I–I). The properties comparisons (band gap and NLO effect) in this system have been also systematically studied.
研究领域:
材料科学
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无机化学
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光学材料
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固态化学
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ACS Applied Materials & Interfaces
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2019
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IF 8.456
Deliang Cheng,Lichun Yang,Renzong Hu,Jiangwen Liu,Renchao Che,Jie Cui,Yanan Wu,Wanyu Chen,Jianling Huang,Min Zhu,Yu-Jun Zhao
Developing anodes with a high and stable energy density for both gravimetric and volumetric storage is vital for high-performance lithium/sodium-ion batteries. Herein, an SnSe/few-layered graphene (FLG) composite with a high tap density (2.3 g cm–3) is synthesized via the plasma-milling method, in which SnSe nanoparticles are strongly bound with the FLG matrix, owing to both Sn–C and Se–C bonds, to form nanosized primary particles and then assemble to microsized secondary granules. The FLG can effectively alleviate the large stress generated from the volume expansion of SnSe during cycling based on its superstrength. Furthermore, as demonstrated by the density-functional theory calculations, the Sn–C and Se–C co-bonding benefitting from the formation of substantial vacancy defects on the P-milling-synthesized FLG enables strong affinity between SnSe nanoparticles and the FLG matrix, preventing SnSe from aggregating and detaching even after long-term cycling. As an anode for lithium-ion batteries, it exhibits high gravimetric and volumetric capacities (864.8 mAh g–1 and 1990 mAh cm–3 at 0.2 A g–1), a high rate (612.6 mAh g–1 even at 5.0 A g–1), and the longest life among the reported SnSe-based anodes (capacity retention of 92.8% after 2000 cycles at 1.0 A g–1). Subsequently, an impressive cyclic life (capacity retention of 91.6% after 1000 cycles at 1.0 A g–1) is also achieved for sodium-ion batteries. Therefore, the SnSe/FLG composite is a promising anode for high-performance lithium/sodium-ion batteries.
研究领域:
材料科学
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储能
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电化学
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纳米材料
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电池技术
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高影响因子
ACS Applied Materials & Interfaces
·
2026
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IF 7.8
Berhanu Telay Mekonnen,Daniel Manaye Kabtamu,Sun-Tang Chang,Guan-Cheng Chen,Amil Aligayev,Francisco Javier Dominguez-Gutierrez,Yao-Ming Wang,Sheng-Yu Wang,Wenyi Huo,Chen-Hao Wang
Developing cost-effective, high-performance bifunctional electrocatalysts for the oxygen reduction reaction (ORR) and oxygen evolution reaction (OER) is crucial for advanced clean energy technologies. This work details Sn–Fe bimetallic nanoparticles anchored on S,N-codoped graphitic carbon nitride (C3N4)-derived tubular carbon (SnFe/SNC_T), which are synthesized via a facile pyrolysis method at 850 °C (SnFe/SNC_850). The optimized SnFe/SNC_850 catalyst, which is characterized by a distinct bamboo-like tubular morphology, demonstrates superior ORR activity with a half-wave potential (E1/2) of 0.86 V vs RHE in 0.1 M KOH, surpassing commercial Pt/C (0.82 V). Furthermore, it exhibits excellent OER performance, requiring only 340 mV overpotential to achieve 10 mA cm–2, and displays remarkable overall bifunctionality. When SnFe/SNC_850 is integrated into an anion exchange membrane fuel cell (AEMFC), it delivers a peak power density of 277 mW cm–2, significantly outperforming Pt/C-based cells (168 mW cm–2). The catalyst also demonstrates exceptional durability, with only 20 mV of E1/2 decay after 30,000 cycles, compared to 50 mV for Pt/C. This enhanced performance is attributed to the synergistic interplay between Fe–Nx/Fe–Sx active sites and intermetallic Fe3SnC/FeS domains. These findings establish SnFe/SNC_850 as a highly promising nonprecious-metal bifunctional electrocatalyst for practical energy-conversion applications, paving the way for sustainable clean-energy solutions.
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高影响因子
JOURNAL OF MATERIALS SCIENCE
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2023
·Vol. 58
·期 22
·9382-9393
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IF 4.5
Wang Bingying,Zhang Keke,Gao Yijie,Liu Peng,Liu Bo,Zhang Zhansheng
The trend toward miniaturized and highly integrated chip packaging has created a pressing need for lead-free solders with high strength, toughness, and conductivity. In this paper, we designed a scheme of Al 2 O 3 -modified nanomaterial-reinforced low silver Sn1.0Ag0.5Cu (SAC105) solder matrix. To begin with, a novel amorphous carbon and nickel core–shell structure plating modified on Al 2 O 3 (C/Ni/Al 2 O 3 ) were prepared by the electroless plating method. Then, the nano-C/Ni/Al 2 O 3 particle as reinforcement phase was mixed into the matrix solder alloy by ultrasonic vibration stirring. Finally, the morphology and relationship between coated carbon, deposited nickel and original solder interface were analyzed. The microstructure and main properties of the modified solders were also investigated. The experimental results suggested that amorphous carbon and nickel film were prepared on the surface of Al 2 O 3 by electroless plating method. The outer layer of nano-Al 2 O 3 was coated with non-uniform thickness of nickel and carbon coatings. The mass percentage of amorphous carbon was about 3.50%. Adding C/Ni/Al 2 O 3 (0–0.5%) into the SAC105 solder matrix resulted in a gradual increase in conductivity and wettability. The strength and toughness of the modified solder alloy improved as well with the adjunction of reinforced phase. The tensile fracture surface exhibited from a mixture of ductile and brittle, characterized by dimples and cleavage surface, to a purely ductile mode consisting mainly of dimples.
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JOURNAL OF THE ENERGY INSTITUTE
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2024
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IF 5.6
Haonan Shi,Sihao Shu,Zhongze Wang,Xing Zhang,Xiaoyu Gu,Jixiang Chen
Deoxygenation of fatty acid esters in aqueous phase using in-situ generated H 2 has emerged as a promising approach to producing sustainable diesel-like hydrocarbons. In this study, we employed a solvothermal method to synthesize novel Ni–Sn metal–organic frameworks (MOFs) with a homogeneous distribution of Ni and Sn elements. Subsequently, various Ni–Sn intermetallic compounds (IMCs) encapsulated with a porous carbon layer (<3 nm) (Ni–Sn IMC@C) were prepared through the facile pyrolysis of metal–organic frameworks under a controlled N 2 atmosphere. Applying methyl palmitate as model reactant and methanol as hydrogen donor, Ni 3 Sn 2 IMC@C gives approximately 100% conversion and 93% yield towards n-C 15 and n-C 16 alkanes at 330 °C, without significant deactivation during the recycling for five times. The deoxygenation pathway is dominated by decarbonylation (DeCO) on Ni–Sn IMCs. In Ni–Sn IMCs, the oxophilic nature of Sn, along with its charge transfer with Ni, enhances the adsorption of an η 2 (C, O)-aldehyde configuration. The strategic isolation of adjacent Ni by Sn effectively inhibits methanation and C–C bond hydrolysis, reducing H 2 consumption and increasing carbon yield. Moreover, the ultrathin porous carbon encapsulation not only prevents the loss and sintering of Ni 3 Sn 2 IMC under harsh hydrothermal condition but also mitigates mass transfer limitation. Surface oxidation of Ni 3 Sn 2 IMC, particularly the formation of SnO 2 , is detrimental to deoxygenation. Additionally, Ni 3 Sn 2 IMC@C exhibits high hydrocarbon yields (>89.6%) in in-situ aqueous phase deoxygenation of methyl laurate, methyl stearate and methyl oleate. These findings highlight the remarkable potential of MOF-derived catalysts for hydrothermal deoxygenation.
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高影响因子
Journal of Cleaner Production
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2024
·
IF 9.7
Feifei Wang,Sizhi Xu,Nannan Wang,Toyohisa Fujita,Shunyan Ning,Yuezhou Wei,Xinpeng Wang
A silica-based adsorbent (P507@COF-TpAzo/SiO 2 ) with nitrogen and phosphorus donors was prepared for industrial separation and recovery of Sn(IV) by in-situ growth of covalent organic framework (COF) on a silica substrate combined with vacuum impregnation. The materials were tested and analyzed by the scanning electron microscope (SEM), X-ray diffraction (XRD) and other characterization techniques, which demonstrated that the adsorbent has an enormous specific surface area, excellent heat resistance, and a regular morphological structure. The static experimental results showed that the adsorbent displayed remarkable selectivity for Sn(IV) in high HCl and HNO 3 concentration environments, with excellent kinetics (∼60 min) and outstanding adsorption capacities (60.02 mg/g in 3 M HCl, 92.59 mg/g in 3 M HNO 3 ) in different media at 3 M acidity. Cycle performance testing demonstrated that the adsorbent exhibited excellent stability (cycle times ≥8). Analysis using Fourier transform infrared spectroscopy (FT-IR) and X-ray photoelectron spectroscopy (XPS) showed that the synergistic adsorption results of N and P were reflected, mainly by the synergistic complexation of P=O and N=N-C. The potential sites for the adsorption of the adsorbent towards Sn(IV) were predicted by density functional theory (DFT) calculations, and the adsorbent demonstrated a more stable binding energy with Sn(IV). Finally, dynamic separation and efficient enrichment (>210) of Sn(IV) in highly acidic wastewater were realized by designing a penetrating column separation process. P507@COF-TpAzo/SiO 2 satisfied the requirements of the dynamic adsorption experiments, bridging the research gap of dynamic separation, and provides a new strategy for the industrial removal and recovery of Sn(IV), as well as a way for environmental protection and industrial green production.
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高影响因子
NEW JOURNAL OF CHEMISTRY
·
2024
·Vol. 48
·期 38
·16734-16741
·
IF 2.7
Xiaoshuai Zhang,Chengrun Liu,Xiaoyan Yu,Zixuan Wang,Panlai Li,Yawei Shi,Zhijun Wang
Although there has been a considerable amount of research on near-infrared (NIR) phosphor-converted light-emitting diodes (pc-LEDs), narrow-band emission and poor thermal stability continue to be problems associated with NIR phosphors. To solve these problems, La3ZrxSn1−xGa5O14:0.015Cr3+ phosphors with ultra-broadband NIR emission were obtained by partially replacing Sn4+ with Zr4+ through a strategy of multiple lattice site occupancy and cationic modulation, which altered the crystal field environment of the material. The spectrum was broadened, and the luminous intensity and thermal stability of the material were successfully improved. Finally, the phosphor was combined with a blue LED chip package, and the broad prospects of the phosphor in the NIR application field were proved by experiments of level detection, biomedical imaging, and night vision monitoring.
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高影响因子
ACS Applied Materials & Interfaces
·
2026
·
IF 8.2
Yunling Tian,Shuang Li,Zhan Wang,Quanchao Zhuang,Zhicheng Ju,Jiangmin Jiang
Silicon monoxide (SiO), with its high specific capacity and low discharge voltage plateau, stands out as a promising anode material for high-energy lithium-ion batteries. However, the application of SiO anodes suffers from an inferior initial Coulombic efficiency (ICE), the instability of the solid electrolyte interface (SEI) layer, and inferior Li+ transport kinetics, leading to unsatisfactory cycling stability and rate capability. Herein, a LiF/Sn–Li hybrid SEI layer is in situ constructed on chemically prelithiated SiO by spontaneous reaction with SnF2 (SnF2–SiO), driven by the redox potential difference between SnF2 and Li, which induces the reductive decomposition of SnF2 and interfacial chemical transformation. Chemical prelithiation compensates for irreversible lithium loss by introducing additional active lithium, thereby enhancing the ICE of the SiO anodes. Notably, the cooperative effect of LiF and Sn–Li alloy stabilizes the electrochemical interface, enhances Li+ diffusion kinetics, and reduces charge transfer resistance. As expected, the SnF2–SiO delivers a remarkable ICE (99.7%) and cycling stability (1126.0 mAh g–1 after 200 cycles), together with superior overall performance for lithium-ion full batteries (SnF2–SiO//LiFePO4). This work confirms the significance of chemical prelithiation and regulation of the hybrid SEI layer for advancing silicon-based anodes in high-performance lithium batteries.
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PubMed
高影响因子
JOM
·
2022
·Vol. 75
·期 5
·1515-1529
·
IF 2.597
Ge Yang,Liu Zhihong,Yu Zhiqian,Wang Huanwen,Lu Xingwu,Zhang Leru,Xia Longgong
The present study focused on the Cu-Pb system and investigating the distribution behaviors of various minor elements through the equilibration-quenching-EPMA analysis experimental technique. Obtained results showed that: (1) An intermetallic compound consisting mainly of Cu-Pb-Se-Te formed below 956°C. (2) As, Sb and Sn had similar distribution behaviors, which mainly entered the solid Cu phase at the temperature range of 500–900°C, but became concentrated in the liquid alloy phase at temperature range of 900–1060°C, and their distribution ratios increased along with increasing temperature. (3) Bi was mainly found in the liquid alloy phase, and its distribution ratio ranged from 6.8 to 836.5 at the experimental conditions. (4) Se and Te formed an intermetallic alloy phase under 900°C, and they enriched in the liquid alloy phase between 960°C and 1060°C. (5) Au was mainly found in the solid Cu phase at the temperature range of 500–900°C, and its distribution ratio was about 1.5 at 900–1060°C. The distribution ratio of Ag decreased from 8.7 to 2.3 when increasing the temperature from 500°C to 1060°C. Distribution behavior of As, Sb, Bi and Sn is consistent with their interfacial enthalpies with Cu and Pb.
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高影响因子
FOOD RESEARCH INTERNATIONAL
·
2025
·
IF 8
Duan Zhou,Mouming Zhao,Xiaorong Zhong,Ning Liu,Xuefeng Chen,Daoming Li
1,3-diacylglycerol (DAG) is a natural lipid and known as functional oil. Here, we evaluated the potential of different natural deep eutectic solvents (NADESs) in synthesis of 1,3-DAG through Candida antarctica lipase B (CALB)-catalyzed esterification. Interestingly, we found that the 1,3-DAG content could be increased by 19.21 %, 13.10 %, and 8.74 % in three choline chloride (ChCl)-based NADESs, respectively, compared with that in solvent-free system. Confirmatory experiments demonstrated that NADESs could inhibit the acyl transfer of 1,3-DAG through modulating the water activity of the reaction system. Meanwhile, circular dichroism spectra and fluorescence spectroscopy results indicated that NADESs could not change the secondary structure of CALB, but could affect the tertiary conformation of CALB. Furthermore, molecular dynamics studies showed that the NADESs could induce a more compact tertiary conformation of CALB and enhance the sn -1,3 positional selectivity of CALB. Overall, the NADESs could induce a higher 1,3-DAG yield through inhibiting the acyl transfer of 1,3-DAG and enhancing the sn -1,3 positional selectivity of CALB. This study provides theoretical support for enzymatic production of structural lipids in NADESs.
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高影响因子
CERAMICS INTERNATIONAL
·
2022
·
IF 5.532
Yingquan Chen,Rui Li,Yan Zhang,Yanping Long,Na Liu,Haijun Xia,Xiong Luo,Bin Meng
A series of lead-free perovskite-structured high-entropy dielectric ceramics with a composition of (La 0.25 Sr 0.25 Ba 0.25 Na 0.25 )(Ti 0.5 Me 0.5 )O 3 (Me = Sn, Zr, Hf) were designed by doping at both the A and B sites. Specifically, these ceramics were prepared via a solid-state reaction method combined with conventional sintering at 1500 ° C for 10 h. All high-entropy ceramics were consisted of a perovskite-structured single solid solution with an average grain size of 2.78–3.85 μm. Of the three samples, (La 0.25 Sr 0.25 Ba 0.25 Na 0.25 )(Ti 0.5 Sn 0.5 )O 3 exhibited the highest dielectric constant, which remained stable from in 25–312 ° C. All three groups of high-entropy ceramics showed typical relaxor behaviour. The discharge energy density ( W d = 0.31 J/cm 3 ), energy storage efficiency ( η = 90.88%) and breakdown strength ( BDS = 300 kV/cm) of (La 0.25 Sr 0.25 Ba 0.25 Na 0.25 )(Ti 0.5 Sn 0.5 )O 3 were much higher than those of BaTiO 3 ( W d = 0.08 J/cm 3 , η = 46.09%, BDS = 30 kV/cm) and other reported lead-free dielectric ceramics. These results demonstrate that high-entropy (La 0.25 Sr 0.25 Ba 0.25 Na 0.25 )(Ti 0.5 Me 0.5 )O 3 ceramics are promising new candidates for high-performance, lead-free dielectric ceramics.
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