SENSORS AND ACTUATORS B-CHEMICAL
·
2023
·
IF 8.4
Qian Chen,Yunxin Xue,Yali Huang,Wenyan Guo,Mimi Wan,Jian Shen
Efficiently capturing and detecting α-synuclein (α-syn) in the bloodstream is crucial for early Parkinson's Disease (PD) diagnosis. In this study, we achieved efficient α-syn detection using electrochemical methods with Mg-based micromotors containing Fe 3 O 4 /GOx nanoparticles (NPs) and anti-α-syn antibodies. Leveraging the asymmetrical structure of the micromotors, we significantly improved the movement range of the magnesium (Mg) microsphere within the blood environment. By harnessing its enhanced motility in blood, we achieved efficient capture of α-syn in whole blood. Moreover, we developed an electrochemical detection device capable of detecting captured α-syn and amplifying the current signal through GOx's catalytic activity. This novel strategy offers potential insights for early PD detection and timely treatment.
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高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
·
2023
·
IF 8.4
Qian Chen,Wenyan Guo,Dan Fang,Ting Li,Lin Chen,Chun Mao,Mimi Wan,Jian Shen
The efficient capture and detection of circulating tumor cells (CTCs) in blood is very important for the early detection of cancer. In this work, efficient detection of CTCs through electrochemical means utilizing Mg-Based micromotors was realized, the prepared Fe 3 O 4 /P/anti-E nanoparticle was subjected to modification using an aldehyde-amine condensation reaction to attach it to the Mg ball. Utilizing the asymmetrical structure of micromotor, we find that the movement range of the magnesium microsphere has obviously improved. On this basis, efficient capture of CTCs can be realized upon the modification of Fe 3 O 4 /P/anti-E with capturing cyclability ability. Such a behavior can be attributed to the anti-E modified on the micromotor can target the epithelial cell adhesion factors on CTCs. Furthermore, A funnel-shaped electrochemical detection device was developed to realize the electrochemical detection of captured CTCs based on the insularity of CTCs. The strategy can potentially provide new visions for the early detection and timely treatment of cancer.
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CATALYSIS COMMUNICATIONS
·
2016
·
IF 3.389
Xiaomin Xiang,Bin Zhang,Guoqiang Ding,Jinglei Cui,Hongyan Zheng,Yulei Zhu
The oxidation of furfural in H 2 O 2 and H 2 O 2 –Mg(OH) 2 system were systematically investigated and a rational explanation for the reaction mechanism was proposed. 2-formyloxyfuran, from selective oxidation of HC O group in furfural, was a crucial intermediate. The addition of Mg(OH) 2 suppressed the oxidation of furan ring of furfural and enhanced selectivities of 2(5H)-furanone (44.8%) and succinic acid (38.0%). FT-IR, Gaussian calculation and experimental results indicated that the process of furfural oxidation with H 2 O 2 is homogeneous, and the synergy between dissolved Mg 2 + cations and OH − ions facilitates the HOO − attacking the carbon atom of HC O other than the C C bound of furan ring.
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ELECTROCHIMICA ACTA
·
2013
·
IF 3.777
Wei Wang,Bo Jiang,Weiyi Xiong,Zhen Wang,Shuqiang Jiao
A nanoparticle Mg-doped Li 4 Ti 5 O 12 with a grain size of 20–30 nm has been successfully synthesized through a simple hydrothermal method . The first-principle simulations are employed to theoretically study the crystal structure, unit cell volume, lattice parameters , and band gaps. Galvanostatic charge–discharge tests have been carried out, using the as-prepared Li 4 Ti 5 O 12 and Mg-doped Li 4 Ti 5 O 12 as the working electrodes with a voltage range of 0.5–2.5 V vs. Li + /Li. The tests show promising results with high capacity and long term stability. When discharging at 350 mA g −1 (corresponding to a 2 C rate), the discharge capacity remains at 170 mAh g −1 over 100 cycles. As the C-rate rises to an ultrafast charge–discharge rate of 50 C, the discharge capacity can still retain at 115 mAh g −1 . The excellent electrochemical performance is due to both the nanomorphology and better conductivity after Mg doping. The results show that the Mg-doped Li 4 Ti 5 O 12 can act as a fast charge–discharge anode material for high rate lithium-ion batteries (LIBs).
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ChemElectroChem
·
2025
·
IF 3.5
Wenzheng Nan,Shaojiu Yan,Xiang Chen,Sheng Long Dai
Graphical In situ Mg seeds are generated on the lithium metal surface during cycling by incorporating MgCl 2 into the electrolyte. These Mg seeds function as thiophilic sites, which lower the Li nucleation barrier and promote uniform Li nucleation and growth. Consequently, symmetric cells constructed with the carbonate electrolyte can cycle stably for over 400 h under 1 mA cm −2 . Lithium metal, recognized for its extremely low reaction potential and ultrahigh theoretical specific capacity, is regarded as the “Holy Grail” of anode materials. However, the formation of lithium dendrites result in rapid cell capacity degradation and considerable safety issues, hindering its further advancement. In this study, in situ Mg seeds are generated on the lithium metal surface during cycling by incorporating MgCl 2 into the electrolyte. These Mg seeds function as thiophilic sites, which lower the Li nucleation barrier and promote uniform Li nucleation and growth. Consequently, symmetric cells constructed with the carbonate electrolyte can cycle stably for over 400 h at a current density of 1 mA cm −2 and a capacity of 1 mAh cm −2 . Notably, full cells using Li 4 Ti 5 O 12 as the cathode can maintain stable cycling for 300 cycles, achieving a capacity retention rate of 71.9 %. This method has demonstrated its effectiveness in mitigating lithium dendrites formation and enhancing the performance of lithium metal batteries.
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Advanced Composites and Hybrid Materials
·
2025
·Vol. 8
·期 1
·1-13
·
IF 21.8
Tang Yubo,Huang Sheng,Chen Wei-chih,A Garu,Linghu Xitao,Wa Qingde,Huang Shuai,Chen Jian
Zn-Mn alloys are particularly promising biodegradable implant materials, but they are plagued by poor mechanical performance. In this work, a Zn-Mn alloy with ultrahigh strength and excellent ductility was achieved through addition of trace Mg (0.1 wt%) and equal channel angular pressing (ECAP). Specifically, the ECAP processed Zn-0.5Mn-0.1 Mg alloy exhibits an ultimate tensile strength (UTS) of 428 MPa, which is highest ever achieved in Zn-Mn-based alloys, along with a good elongation (EL) of 39%. In addition, the alloy exhibits excellent antibacterial performance against Staphylococcus aureus ( S. aureus ) and Escherichia coli ( E. coli ). Trace Mg addition results in the formation of Mg 2 Zn 11 and MgZn 2 nano-precipitates in the alloy, which effectively pins grain growth during dynamic recrystallization (DRX) and postpones the inverse Hall–Petch relation. Consequently, the alloy possesses quite fine grains of an average grain size (AGS) of 0.71 μm, much smaller than that of its counterpart without Mg (AGS = 2.54 μm). The ultrahigh strength of the alloy is mainly ascribed to grain boundary strengthening and precipitation strengthening. The remarkable ductility of the alloy is related to deformation twinning suppression, pyramidal < c + a > slip activation, and low dislocation density.
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Journal of Materials Research and Technology-JMR&T
·
2025
·
IF 6.6
Ziyi Zhu,Hongbin Ma,Zhen Liu,Siting Cheng,Caihong Zhang,Rulin Jia,Peipeng Jin,Yupeng Wei
The corrosion behaviors of Mg-3Nd alloy in Qinghai Lake water (Cl − , SO 4 2− , HCO 3 − , CO 3 2− ) were studied, focusing on synergistic anion effects between Cl − and HCO 3 − . HCO 3 − demonstrates dual roles in Mg alloy corrosion mechanisms: it induces localized micro-galvanic coupling effects that exacerbate anodic dissolution during initial exposure, while facilitating the progressive formation of a composite Mg(OH) 2 /MgCO 3 passivation layer through interfacial precipitation reactions during long-term immersion. Cl − induced interfacial degradation triggers lamellar spallation of Mg(OH) 2 /MgCO 3 layers. The results revealed the competitive effects of anion interactions and transient protective phase MgCO 3 on corrosion behaviors of Mg alloy, providing insights for the design of corrosion-resistant lightweight equipment in salt-lake water environments.
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SusMat
·
2025
·
IF 21.3
Xuechun Hu,Yuchen Pang,Chaoqun Li,Xiaoyue Zhang,Xuebin Yu,Fang Fang,Guanglin Xia
Magnesium hydride (MgH 2 ) has been regarded as an attractive candidate for solid-state hydrogen storage, yet its practical applications are limited by the requirement of elevated temperatures and sluggish hydrogen uptake and release kinetics. Herein, TiO 2 polyhedral frameworks with uniformly distributed V 2 O 5 (denoted as V 2 O 5 /TiO 2 ) are constructed to improve hydrogen storage performance of Mg/MgH 2 . During the reversible hydrogenation and dehydrogenation process, metallic V and Ti along with low-valent Ti- and V-based oxides are in situ formed. Among them, metallic V supported on TiO 2 exhibits the lowest hydrogen adsorption energy, enabling superior catalytic performance over TiO 2 and V 2 O 5 . As a result, the peak dehydrogenation temperature of MgH 2 decreases to 215°C, 105°C lower than that of pristine MgH 2 , with a decrease of the apparent activation energy from 139.50 kJ·mol −1 to 68.99 kJ·mol −1 . Moreover, electron migration from V toward TiO 2 leads to charge accumulation around Ti and O atoms, shifting the V 3 d -band center toward the Fermi level and thereby improving the catalytic function of V's d-electrons, facilitating hydrogen dissociation without energy barriers. Therefore, the V 2 O 5 /TiO 2 -catalyzed Mg absorbs 4.12 wt% H 2 under an ultralow pressure of 1 bar at 25°C. This provides a new strategy for developing advanced Ti and V-based catalysts for mild-condition hydrogen storage of MgH 2 .
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ACS Omega
·
2019
·
IF 2.584
Weiwei Wu,Xiaoming Yu,Yan Zhao,Xiran Jiang,Huazhe Yang
Biodegradable Mg alloys have good bioactivity and suitable mechanical properties, which is desirable for application in the clinical fields. However, the biocompatibility of Mg alloys during the degradation process has always been a concern. In this paper, the corrosion behavior of AZ91 alloys in a simulated cell culture environment was studied, especially the insoluble corrosion product during the degradation was characterized, and the biocompatibility of the insoluble corrosion products was evaluated. The results of immersion test showed that the corrosion rate of the AZ91 alloy was low under the condition of high CO2 and humidity, especially in phosphate-buffered saline. Moreover, the insoluble corrosion product was MgCO3·3H2O, which showed a needle-like, circular aggregated, and square-radial feature. Meanwhile, MgCO3·3H2O showed poor cell biocompatibility by increasing the pH and Mg2+ content of the culture solution, which may affect the biocompatibility of Mg alloys.
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PubMed
高影响因子
JOURNAL OF ALLOYS AND COMPOUNDS
·
2022
·
IF 6.371
Hui Liang,Hao Zhang,Yi Zong,Heng Xu,Jun Luo,Xijun Liu,Jie Xu
Doping engineering is an effective strategy to improve the hydrogen storage capacity of magnesium-based materials. Here, we report a magnesium composite containing trace amounts of nickel catalyst (Ni-Mg), in which Ni and Mg layers form a new structural phase. The test shows that Ni-Mg composite has a hydrogen storage capacity of 7.5 wt%, with rapid absorption/desorption kinetics and stable reversible absorption/desorption performance on cycling. Ni-Mg exhibits a superior hydrogen storage performance as compared to the MgNi alloys and Mg-based materials previously reported in the literature. We conclude that a new MgNi phase and MgNi 2 intermetallic compound are formed during the H 2 adsorption process . Based on the theoretical calculations, we show that Ni facilitates hydrogenation by accelerating the dissociation of H 2 molecules into the H atoms, while the MgNi phase formed during the hydrogenation is conducive to the subsequent dehydrogenation, promoting H atoms diffusion between the subsurface and the surface. This work provides a guidance for the development of the efficient hydrogen storage materials .
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ACTA PHYSICO-CHIMICA SINICA
·
2023
·
IF 10.9
Wencheng Fang,Dong Liu,Ying Zhang,Hao Feng,Qiang Li
Photoelectrochemical water splitting using semiconductor materials is one of the most promising methods for converting solar energy into chemical energy. Among the commonly used semiconductors, p-type CuBi 2 O 4 is considered one of the most suitable photocathode materials and can allow a theoretical photocurrent density of about 20 mA·cm −2 for photoelectrochemical water splitting. However, due to severe charge carrier recombination, the obtained photocurrent density is much lower than the theoretical value. Highly efficient photoelectrochemical performance relies on fast charge carrier separation and transport, and prompt reaction kinetics. In this study, we report the development of a polyoxometalate-modified CuBi 2 O 4 /Mg-CuBi 2 O 4 homojunction photocathode to improve both the bulk and interfacial charge carrier transport in the photocathode. For the bulk of the photocathode, the built-in electric field originating from the CuBi 2 O 4 /Mg-CuBi 2 O 4 homojunction promotes the migration of photo-excited electrons on the conduction band from pure CuBi 2 O 4 to Mg-doped CuBi 2 O 4 . Additionally, the electric field facilitates the transfer of holes from the valence band of Mg-doped CuBi 2 O 4 to pure CuBi 2 O 4 . This directional transfer of both photo-excited electrons and holes plays a significant role in promoting separation and suppressing the recombination of the charge carriers. On the surface of the photocathode, the reduced polyoxometalate co-catalyst Ag 6 [P 2 W 18 O 62 ] (AgP 2 W 18 ) was used as a proton sponge to accelerate surface reaction kinetics and suppress carrier recombination. These synergistic effects improved the photo-generated charge carrier transfer and reaction kinetics. As a result, the novel photocathode displayed excellent photoelectrochemical properties, and the photocurrent density was observed to be −0.64 mA·cm −2 at 0.3 V vs. RHE, which is better than that of −0.39 mA·cm −2 for a pure photocathode. Furthermore, the novel photocathode had an applied bias photon-to-current efficiency (ABPE) higher than 0.19% at 0.3 V vs. RHE. In contrast, the pure photocathode had an ABPE of ~0.12% under the same conditions. Additionally, when H 2 O 2 was used as an electron scavenger, the photocurrent density was −3 mA·cm −2 at 0.3 V vs . RHE, which is an improvement of approximately 1.5 times compared to the pure photocathode. Furthermore, the charge separation and charge injection efficiency of the novel photocathode were significantly improved compared with the pure photocathode. The experimental results conclusively indicate that the formation of the CuBi 2 O 4 /Mg-CuBi 2 O 4 homojunction and AgP 2 W 18 modification played a significant role in the improved performance of the CuBi 2 O 4 photocathode. The performance of the novel photocathode was comparable with the results reported in previous studies, demonstrating its promising potential in real applications. Download: Download high-res image (83KB) Download: Download full-size image
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TRANSACTIONS OF NONFERROUS METALS SOCIETY OF CHINA
·
2025
·Vol. 35
·期 11
·3919-3932
·
IF 4.7
Jia ZHAO,Zhi-tao SONG,Gui-min LU
The alloying process of Mg-La in NaCl-KCl-MgCl 2 -LaCl 3 (NKML) melts during electroreduction was elucidated using electrochemical techniques and deep potential molecular dynamics (DPMD) simulations. In the NKML system, the Mg 2+ /La 3+ electrodeposition on the tungsten (W) electrode at 973 K was found to be a one-step process. The nucleation of metal ions on the electrode surface followed an instantaneous nucleation mode and was not influenced by the alloying process. The redox potential and underpotential deposition behavior of the metal ions in the NKML system were accurately predicted by the DPMD simulations, confirming the alloying process of the Mg-La. Additionally, scanning electron microscopy with energy dispersive spectroscopy (SEM-EDS) analysis results confirmed that the cathodic deposits consisted of a bright phase and a dark phase, corresponding to the Mg-La alloys and Mg, respectively. The distribution of electrolytic products suggests that the cathodic deposit initially favors the Mg phase, with the Mg-La alloy forming more easily when the Mg source in the melt is depleted.
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