JOURNAL OF CRYSTAL GROWTH
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2025
·
IF 2
Kang Han,Dandan Gong,Chengwei Du,Lijuan Zhang,Lu Wang,Jing Lian,Aniruddha Majumder,Jie Lu
The influence of 2,2,6,6-Tetramethylpiperidinooxy (TEMPO) cellulose nanofibers (TCNF) on the nucleation and growth of sulfathiazole (STZ) crystals is uncovered, aiding in the precise control of drug crystal morphology. To elucidate the mechanism by which TCNF regulates the nucleation and growth of STZ crystals, cooling crystallization experiments and molecular simulations were conducted. Initially, the crystal forms of STZ in pure water were determined. Subsequently, crystallization experiments with the addition of TCNF were conducted. The experiments aimed to investigate their effects on crystal form and crystal habits. The results revealed that a pure Form III was obtained due to the hydrogen bonding interactions on the surface of TCNF. Molecular simulations helped better explain the influence on specific crystal faces. This study indicates that the influence of TCNF on the characteristics of STZ crystals is mediated through interaction with the z-axis crystal facets, leading to the formation of block-shaped crystals. In addition, the higher concentration of TCNF forms a local closed space, resulting in blocked mobility, allowing STZ molecules in the solution to grow at the defects of STZ crystallization.
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INDUSTRIAL CROPS AND PRODUCTS
·
2024
·
IF 5.6
Lu Liu,Xuejun Zhang,Lin Chen,Feng F. Hong
Many attempts have been made on the efficient production and high value-added application of a nano-scale cellulose product (nanocellulose), composed of plant nanocellulose fiber (PNC) and bacterial nanocellulose (BNC). However, the functional performance of products composed of PNC and BNC is poorly understood. It was hypothesized that nanocomposites based on these two nanocellulose types would show similar physicochemical properties, biocompatibility, and therapeutic efficacy for wound treatment, despite the presence of a unique 3D nanofibril network in BNC. With the aim of determining the more efficient hemostatic sponge for widespread application, two nanocomposite sponges produced from TEMPO-oxidized PNC (OPNC) and BNC (OBNC) were therefore compared in detail with two commercial hemostatic sponges. Two nanocomposite sponges, OPNC/COL/CS and OBNC/COL/CS, were obtained via electrostatic self-assembly using a combination of anionic oxidized cellulose and cationic chitosan (CS) to wrap collagen (COL) in a sandwich structure. The physical characterization of the two nanocomposites revealed minimal differences. The results demonstrated that both OPNC/COL/CS and OBNC/COL/CS exhibited strong antimicrobial properties, with similar in vitro hemocompatibility, in vivo hemostatic efficiency, histocompatibility, and biodegradability. Further experiments using two animal bleeding models demonstrated that both materials outperformed commercial hemostatic sponges in blood absorption and hemostatic efficacy.
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JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2025
·
IF 9.7
Yao Gong,Wenxin Qi,Wenyi Lu,Qing Chang,Yijun Xie,Jiao Wang,Xiaoyong Deng
Diabetic wounds are highly prone to persistent pathogenic infections due to the complex nature of their microenvironment, which significantly hinders the healing process under hyperglycemic conditions. In this study, we developed a bio-heterojunction enzyme system consisting of hollow CeO 2 /Ti 3 C 2 T x MXene quantum dots (CeO 2 @MQD) integrated with glucose oxidase (GOx-CeO 2 @MQD). The GOx-CeO 2 @MQD system exhibits multifunctional enzymatic activities, including peroxidase (POD) and catalase (CAT)-like activity, resulting in the production of •OH and O 2 , alongside the consumption of glucose and glutathione (GSH). The incorporation of GOx effectively mitigates the hyperglycemic microenvironment by catalyzing glucose, leading to a significant increase in H 2 O 2 production, which is subsequently converted into bactericidal •OH through POD activity. Furthermore, H 2 O 2 can be catalyzed into H 2 O and O 2 via the CAT pathway, thereby alleviating inflammation caused by the excessive accumulation of reactive oxygen species. In vitro antibacterial assays demonstrated that the GOx-CeO 2 @MQD system achieved remarkable bactericidal efficiencies of 99.99% against E. coli and S. aureus at concentrations of 12.5 ppm and 2.0 ppm, respectively. In vivo experiments further revealed that GOx-CeO 2 @MQD significantly promoted angiogenesis, accelerated wound epithelialization, and induced a strong anti-inflammatory response, thus facilitating the regeneration of infected diabetic skin. This study proposes a novel approach for diabetic wound treatment by harnessing the synergistic effects of multiple enzyme-like activities.
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Results in Engineering
·
2024
·
IF 6
Wei Li,Shengxian Chen,Yongqi Lu,Jiangjie Yu,Shiguang Zhao
The co-immobilized laccase-mediator system (LMS) has broad development prospects in the fields of biocatalysis, biochemistry, and environmental remediation. In this study, laccase and mediator molecules were co-immobilized in functionally modified calcium alginate microspheres to improve their catalytic activity and stability and to systematically characterize the physicochemical properties and evaluate the catalytic performance of the co-immobilized laccase-mediator system. The co-immobilized LMS was used to catalyze the synthesis of theaflavins (TFs) from tea polyphenols, improve the catalytic efficiency, realize the recycling of the system, and explore the safety of the catalytic products. The results showed that the catalytic efficiency of the co-immobilized LMS was significantly improved and the relative activity remained above 50% after 10 cycles. The in vitro safety of the catalytic product was verified by Human hepatocellular carcinoma (HepG2) cell-related indexes. The results show that the co-immobilized laccase mediator system has great development potential in the industrial application of theaflavins.
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SEPARATION AND PURIFICATION TECHNOLOGY
·
2024
·
IF 8.1
Diejing Feng,Bingxu Lu,Wenjing Wu,Shenggang Yang,Yukun Sun,Bo Bai,Shijie Li
The regulation of heterogeneous material properties to strengthen the peroxymonosulfate activation to destroy refractory pharmaceuticals remains a challenge. Herein, a promising nitrogen-deficient catalyst (FeCN) with single atom Fe and Fe 2 O 3 nanoparticles dispersing on g -C 3 N 4 matrix was synthesized and applied as a competent peroxydisulfate (PDS) activator for tetracycline (TC) degradation under visible light. The K-edge X-ray absorption fine structures and 57 Fe Mössbauer measurements confirmed the unique configuration of Fe 2 O 3 and single atom Fe active sites (pyrrolic and pyridinic FeN 4 ) induced by the neighbouring nitrogen vacancies. The theory calculations and experiments provided a deep insight into the PDS activation and TC degradation via radical and non-radical pathways. The pyrrolic FeN 4 active sites dominated the electron transfer, while the pyridinic FeN 4 and Fe 2 O 3 decomposed PDS to produce free radicals. The synergistic effect between the Fenton-like oxidation and photocatalysis is responsible for efficient TC degradation. This study offers a new strategy by integrating novel catalysts and advanced oxidation technology for effective wastewater purification.
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FOOD CHEMISTRY
·
2024
·
IF 8.5
Xinling Wu,Qiang Zhang,Deyi Zhou,Li Zhang,Haigen Zhou,Xiaodi Gao,Xuwen Fang,Chao Huo,Jinsong Zhang
Pickering emulsions (PEs) have wide applications in delivering nutraceuticals. However, the impact of extracting nanocellulose from corn stover on stabilizing PEs and delivering nutraceuticals remains unclear. In this study, four types of nanocellulose, cellulose nanocrystals (CNC), cellulose nanofibers (CNF), lignin-containing cellulose nanocrystals (LCNC), and lignin-containing cellulose nanofibers (LCNF) were successfully prepared from corn stover, an agricultural waste. Among them, LCNC and LCNF exhibited stable reticulated microstructures, lower crystallinity, and excellent thermal stability. Besides, lignin enhanced the nanoparticles' hydrophobicity, promoting the formation of more ideally amphiphilic particles, resulting in denser emulsions at the oil-water interface. Furthermore, emulsions stabilized by LCNC and LCNF demonstrated remarkable resistance to quercetin degradation under UV light exposure (with residual level exceeding 90 %) and improved quercetin's bioaccessibility during the in vitro digestion tests, achieving the highest bioaccessibility of 48.3 %. This study provided an innovative perspective on utilizing stover-derived materials for stabilizing PEs and delivering lipophilic nutrients.
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Energy & Environmental Science
·
2024
·Vol. 17
·期 8
·2945-2955
·
IF 32.4
Binyang Tuo,Ziyu Wang,Ziqiu Ren,Hanwen Zhang,Xinqi Lu,Yiqiang Zhang,Shuangquan Zang,Yanlin Song
The stability issues of perovskite solar cells (PSCs), especially illumination stability, have become a bottleneck that limits their further development, which needs urgent attention. Herein, we present a novel strategy for enhancing the illumination stability of PSCs using the radical scavenger of 2,2,6,6-tetramethylpiperidine-1-oxyl (TEMPO) to interrupt photoinduced radical decomposition. It is demonstrated that selectively generated triiodide with the addition of TEMPO can obliterate I-deficient phases during crystallization and passivate defects. More importantly, the photochemical decomposition of targeted perovskite polycrystalline films has been observably inhibited by the free-radical elimination effect of TEMPO. By harnessing TEMPO's defect passivation and radical-scavenging effects, target perovskite devices achieve an outstanding power conversion efficiency of 25.03%, maintaining over 90% of their initial efficiency after continuous maximum power point tracking under ISOS-L-2 conditions at 65 °C for 1000 hours. We demonstrate a novel perspective on the management of photochemical behavior in perovskite devices.
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Frontiers in Bioengineering and Biotechnology
·
2024
·
IF 4.3
Wang Dan,Huang Guifang,Yu Chunming,Wang Yawen,Baek Nawon,Zhu Ruofei
The emergence of environmental endocrine disruptor chlorobenzene (CB) in surface water and its potential environmental impacts have attracted serious global attention. It is still very difficult to achieve effective degradation of it by catalytic oxidation process under mild conditions. Here, an optimized method for degrading CB in aqueous solution using Trametes versicolor laccase and surfactant-assisted laccase-mediator (SALM) system was investigated. The use of a Tween 80 surfactant enhanced the solubility of CB and promoted its efficient degradation. Under favorable conditions, the SALM system yielded a degradation efficiency of 43.5% and a dechlorination efficiency of 41.55% for CB (25 mg/L) within 24 h. The possible degradation pathway of CB by this system was speculated by detecting the intermediates produced during the reaction. The outcome of the proliferation assays on MCF-7 human breast cancer cells demonstrated a reduction in the estrogenic activity of the CB solution following treatment with the SALM system. Furthermore, the influence of the quantity and positional variation of chlorine substituents on the degradation process was methodically investigated. Moreover, molecular analyses were employed to study the detailed interaction mechanism between laccase and CB, which revealed that the hydrophobic interaction contributed dominantly to binding process. These findings provide an efficient and environmentally friendly degradation system for the development of purification strategies for halogenated pollutants.
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Nano Research
·
2024
·
IF 9.5
Tang Jianfu,Fan Xueqin,Huang Haozhou,Dong Xiaofei,Li Xueqi,Wang Peiru,Yin Ran,Xie Yanjun,Li Jian,Tan Gang,Pang Zhenqian,Gan Wentao
Using biodegradable material derived from renewable resources as petroleum-based plastics replacement is a promising way towards sustainable development. However, the insufficient mechanical properties and complex manufacturing process of bioplastics still need to be improved for high-quality food packages. Herein, we report a top-down strategy to transform natural wood into a clear wood packaging film through scalable delignification and polyvinyl alcohol (PVA) infiltration. The wood packaging film demonstrates a laminated structure with completely collapsed cell walls and PVA intertwined together after energy-saving air drying, resulting in high light transmittance with low haze, good mechanical performance, and high barrier performance for oxygen and water vapor. Molecular dynamics simulations reveal the underlying fracture mechanism between cellulose and PVA, which effectively enhances the Young’s modulus and strength of the wood packaging film. These findings contribute to the development of biodegradable and strong packaging materials, as well as other food-related applications, using sustainable wood.
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Polymers
·
2024
·Vol. 16
·期 6
·805
·
IF 4.7
Xinyuan Wan,Xiaojian Xia,Yunxiang Chen,Deyuan Lin,Yi Zhou,Rui Xiong
Thermal conductive coating materials with combination of mechanical robustness, good adhesion and electrical insulation are in high demand in the electronics industry. However, very few progresses have been achieved in constructing a highly thermal conductive composites coating that can conformably coat on desired subjects for efficient thermal dissipation, due to their lack of materials design and structure control. Herein, we report a bioinspired thermal conductive coating material from cellulose nanofibers (CNFs), boron nitride (BN), and polydopamine (PDA) by mimicking the layered structure of nacre. Owing to the strong interfacial strength, mechanical robustness, and high thermal conductivity of CNFs, they do not only enhance the exfoliation and dispersion of BN nanoplates, but also bridge BN nanoplates to achieve superior thermal and mechanical performance. The resulting composites coating exhibits a high thermal conductivity of 13.8 W/(m·K) that surpasses most of the reported thermal conductive composites coating owing to the formation of an efficient thermal conductive pathway in the layered structure. Additionally, the coating material has good interface adhesion to conformably wrap around various substrates by scalable spray coating, combined with good mechanical robustness, sustainability, electrical insulation, low-cost, and easy processability, which makes our materials attractive for electronic packaging applications.
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CHEMICAL ENGINEERING JOURNAL
·
2024
·
IF 13.3
Hui Liu,Hongxiang Zhu,Shanshan Yu,Zihan Zhao,Yujie Duan,Siyuan Xia,Huanhuan Huang,Lei Wang,Hui He
Self-erasing materials with stepwise decryption are ideal for the security of information transmission. Here, a time-locked self-erasing material (TLSEM) with stepwise decryption is constructed by means of cellulose nanocrystal (CNC) bridge bond phosphor donor and gold nanoclusters (GNCs) acceptor. CNC integrated donor and acceptor, inhibited self-aggregation, enhanced the fluorescence intensity, and stability of GNCs and improved the energy transfer efficiency (49.65 %). The color pattern of TLSEM presented on the time scale was regulated by the donor and acceptor ratios based on the change in the energy transfer degree. Therefore, a TLSEM with different donor and acceptor ratios were implemented for the information encryption array, which presented the “time lock” information at 2 min and completely disappeared after 15 min through pH and cysteine encoding, and changed significantly from intricate orange–red–green to correct green with time. This time-dependent self-erasing material with stepwise decryption is excellent for special information transmission security.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2024
·
IF 7.7
Jiawen Sun,Xingda Liu,Jizhou Duan,Kunyan Sui,Xiaofan Zhai,Xia Zhao,Yuqing Zhu,Ding Guo,Baorong Hou
Nanocomposite polymer coatings are being used as a new generation of marine antibiofouling coatings because of their toxin-free chemical composition and ease of large-scale adoption. Cellulose nanocrystal (CN) exhibits significant potential for composite reinforcement. Herein, CN was surface-modified via α,ω-bis(3-(2-hydroxyl-terminated polydimethylsiloxane (HTPDMS), resulting in dihydroxyl-terminated poly(dimethylsiloxane)-grafted CN (HP-g-CN). The amine-terminated PDMS as the foundational component was sequentially reacted with isophorone diisocyanate, isophthalaldehyde, and carbon disulfide to produce PDMS-based poly (urea-thiourea-imine) (PDMS-PUTI). Subsequently, a composite (PDMS-PUTI/HP-g-CN) was produced through physical blending. The intrinsic imine bonds and dynamic hydrogen-bonding network were responsible for the self-healing properties, which achieved a healing efficiency of up to 89.2 %. HP-g-CN was grafted with the non-leaching lubricant, HTPDMS, resulting in improved mechanical properties (1.38 MPa of ultimate strength) and adhesion strength (2.43 MPa), along with the self-cleaning and self-lubricating performance (0.700 coefficient) of the coating. Additionally, the fouling resistance to bovine serum albumin (BSA, 10.44 μg cm −2 ), bacteria (∼97.08 % and ∼ 98.05 % reduction for Pseudomonas sp. ( P. sp.) and Shewanella sp. ( S. sp.), respectively), and diatoms (∼27 cells mm −2 ) was further enhanced. Marine field tests conducted over 90 days revealed that the coatings were static fouling-resistant for an extended period. This study demonstrated a multifunctional, high-performance, and environmentally friendly nanocomposite polymer coating for preventing marine biofouling.
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