CERAMICS INTERNATIONAL
·
2026
·
IF 6
Yutong Zhang,Guoquan Yang,Jieling Zhang
Tendon injuries are common in table tennis and remain difficult to repair because of oxidative stress and limited regenerative capacity. This study developed an electrospun PPDO-COL-I/ x %CeMnBG fiber membrane with potential applications in tendon repair. The membranes exhibited uniform, bead-free morphology, good flexibility, a tensile strength of 5.89 MPa, and an elongation at break of 80%. All groups maintained cell viability above 80% over 5 days, while PPDO-COL-I/1.5%CeMnBG showed the best cell performance, with 110% proliferation on day 5. This group also displayed excellent ROS-scavenging activity, achieving 60% DPPH, 40% SOD, and 60% ABTS clearance, together with reduced intracellular ROS and enhanced L929 migration. These results indicate that PPDO-COL-I/1.5%CeMnBG is a potential candidate for tendon regeneration by integrating structural support, bioactive ion release, and antioxidant protection.
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DOI
高影响因子
Materials Today Bio
·
2026
·
IF 11
Zhipeng Li,Yaoyao Wu,Jialin Wu,Cheng Zhang,Xinsheng Cheng,Hongzhen Zhang,Shikai Wang
Ulcerative colitis (UC) is a chronic inflammatory bowel disease characterized clinically by recurrent abdominal pain and bloody diarrhea, for which there is currently a lack of curative therapeutic strategies. In recent years, neutrophil extracellular traps (NETs) have been identified as playing a key role in the pathogenesis of UC, emerging as a potential therapeutic target. Although deoxyribonuclease I (DNase I) can exert therapeutic effects by degrading the DNA backbone of NETs, its clinical application is limited by inherent drawbacks, including poor in vivo stability, low bioavailability, and inefficient penetration of biological barriers. Herein, this study constructed a biomimetic membrane-based nanodelivery system. Initially, zeolitic imidazolate framework-8 (ZIF-8) was used to encapsulate DNase I, forming ZD nanoparticles to enhance enzymatic stability. Subsequently, these nanoparticles were coated with bacterial outer membrane vesicles (BOMVs), yielding the final BVZD composite system, designed to improve targeting to inflammatory sites. The BVZD system exhibited suitable particle size, good biocompatibility, and a demonstrated ability to specifically accumulate in the inflamed intestinal regions of a UC model. Both in vitro and in vivo experiments confirmed that BVZD effectively degraded NETs, suppressed endoplasmic reticulum stress (ERS) by downregulating the expression of prostaglandin-endoperoxide synthase 2 (PTGS2), and promoted the repair of the intestinal epithelial barrier. These findings highlight the promising therapeutic potential of BVZD for the treatment of UC.
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产品关联
DOI
高影响因子
Nanomaterials
·
2025
·Vol. 15
·期 12
·897
·
IF 4.3
Haiwei Wu,Jiaming Zhang,Fangbo Zhao,Wei Fan,Song Yang,Jun Ma
In chlorination disinfection treatment, residual iodinated X-ray contrast media (ICMs) are the precursors to iodinated disinfection by-products (I-DBPs). This study employed CoFe2O4nanoparticle catalytic peracetic acid oxidation (CoFe2O4/PAA) to remove iopamidol (IPM) and control I-DBP formation. The experimental results demonstrated that over 90% of the IPM degradation was achieved in 40 min. The metastable intermediate (≡Co(II)-OO(O)CCH3), rather than the alkoxyl radicals, was identified as the dominant oxidation species (ROS). The electron transfer pathways between the metastable intermediate and IPM were oxygen-atom transfer and single-electron transfer. The monoiodoacetic acid formation potential (MIAAFP) was investigated. In ultraviolet-activated ClO−(UV/chlorine), a portion of I−generated through IPM dehalogenation underwent conversion to reactive iodine species (RIS), consequently elevating the MIAAFP. In CoFe2O4/PAA, the MIAAFP was less than 43% of that in UV/chlorine, which can be attributed to the complete conversion of I−into iodate IO3−without generating RIS. CoFe2O4/PAA is thus a promising treatment for removing ICMs and controlling I-DBP formation due to the efficient degradation of ICMs while avoiding the generation of RIS.
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产品关联
DOI
PubMed
高影响因子
iScience
·
2025
·
IF 4.1
Hechen Shen,Xu Bao,Bingcai Qi,Xiaoyu Liang,Yun Chang,Xiaomin Hu,Wenqing Gao,Di Sun
Myocardial infarction (MI) poses a severe threat to human life, and timely reperfusion of ischemic myocardium stands as the most effective treatment approach. However, myocardial ischemia-reperfusion (I/R) could lead to the excessive generation of reactive oxygen species (ROS), worsening myocardial injury. In this investigation, a ROS-responsive injectable hydrogel encapsulating melatonin (MLT) was synthesized. This hydrogel could provide a controlled release of MLT, markedly enhancing its antioxidant, anti-inflammatory, anti-apoptotic, and autophagy-modulating effects, thereby significantly mitigating myocardial ischemia-reperfusion injury (MIRI). Moreover, this study proposes an injection method of ultrasound delivery, which offers significant advantages to MI patients without the necessity of thoracotomy In conclusion, This ROS-responsive hydrogel loaded with MLT established the basis for minimally invasive treatment of myocardial I/R injury, which has considerable potential for the treatment of MIRI.
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产品关联
DOI
PubMed
高影响因子
Journal of Cleaner Production
·
2021
·
IF 9.297
Chuankun Yin,Siji Zhou,Keyi Zhang,Jiale Bai,Yangyang Lv,Xuewen Zhang,Xiaoxia Li,Aihua Xu
p-Nitrophenol (PNP) is one of the highly toxic and mutagenic pollutants existed in aquatic environment. In this work, the crednerite CuMnO 2 nanoflake was prepared and used to degrade PNP with peroxymonosulfate (PMS) as the oxidant. It was found that CuMnO 2 exhibited much higher activity than other Cu-based catalysts such as CuO, Cu 2 O, CuFe 2 O 4 and CuFeO 2 , with 90% of PNP degraded after 10 min under mild reaction conditions. The catalyst was also stable during five successive runs. Sulfate and hydroxyl radicals produced from PMS reduction by Cu(I) species, as well as superoxide ions and single oxygen, contribute to the degradation of PNP. More importantly, the interactions between Mn and Cu species in CuMnO 2 were identified by X-ray photoelectron spectroscopy (XPS), fourier transform infrared spectroscopy (FT-IR) and linear sweep voltammetry (LSV), and were further confirmed by the control experiment with the mixture of Cu 2 O + Mn 2 O 3 . The results implied that the high valent Mn(III) species acted as Lewis acids to withdraw electron from PMS, resulting that the Cu(I) species can be easier oxidized to Cu(II) by PMS with the formation of radicals. These findings provide an ideal bimetallic heterogeneous catalyst and a new mechanism for PMS-mediated reaction.
研究领域:
环境科学
·
催化化学
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DOI
高影响因子
INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
·
2017
·
IF 2.843
Ya-Wen Zhang,Guan Wu,Hui Dang,Kangzhe Ma,Su Chen
Organometal halide perovskites (such as CH3NH3PbX3, X = Cl, Br, I) have received enormous interest due to their strikingly photoelectric properties. Here we develop a facile ligand-assisted reprecipitation method to synthesize NH2CH═NH2PbX3 (NH2CH═NH2+, FA; X = Br and I) perovskite quantum dots (QDs) at room temperature. The FAPbX3 perovskite QDs with uniform monodispersity (sized 4–7 nm) display relatively high photoluminescence quantum yields (PLQYs) of 60–75%. Through manipulating the mixed-organic-cation reactions, we achieve a series of multicolored perovskite QDs with continuously controllable emission wavelengths from 460 to 565 nm. Furthermore, we discuss the influence of ligands (oleic acid and n-octylamine) on PL properties and stabilities of perovskite QDs. Finally, we have successfully designed a white LED via compositing perovskite QDs and poly(methyl methacrylate) (PMMA), which presents a high color rendering index. Considering those remarkable achievements, we believe our work will have great potential to meet various optoelectronic applications.
研究领域:
材料科学
·
光学工程
·
电子工程
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DOI
高影响因子
JOURNAL OF ALLOYS AND COMPOUNDS
·
2026
·
IF 6.7
Jitang Chen,Qian Li,Chengbing Ma,Yupeng Yuan,Huiquan Li
The rational design of heterojunction photocatalysts is essential for overcoming the persistent challenge of charge recombination in solar water-splitting systems. Herein, a step-scheme (S-scheme) AgI/Bi₇O₉I₃ heterojunction was fabricated using a facile one-pot hydrothermal method, where deliberate interfacial engineering enables efficient charge separation and transfer. The optimized heterojunction demonstrated remarkable photocatalytic oxygen (O₂) evolution activity, achieving a rate of 2046.22 μmol·g⁻¹·h⁻¹ under visible-light irradiation (λ ≥ 420 nm)—3.1 and 1.97 times higher than those of pristine AgI and Bi₇O₉I₃, respectively. Ultraviolet photoelectron spectroscopy (UPS) and electron spin resonance (ESR) analyses collectively revealed that a built-in electric field formed at the interface drives the directional migration of electrons from AgI to Bi₇O₉I₃, following an S-scheme charge transfer pathway. This mechanism not only enhances the separation of photogenerated carriers but also preserves strong redox capabilities for the water oxidation reaction. This study presents an effective interfacial engineering strategy for developing high-performance heterojunction photocatalysts and provides fundamental insights into charge behavior in S-scheme photocatalytic systems.
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产品关联
DOI
高影响因子
LETTERS IN ORGANIC CHEMISTRY
·
2024
·Vol. 22
·期 1
·56-60
·
IF 0.7
Xin-Yu Lin,Guo-Jun Chen,Su-Zhe Wu,Ke-Xuan Xu,Xiao-Tian Zhang,Qi Feng
4-Hydroxyquinoline-2(1H)-ones exhibit multiple biological activities, and studying their synthetic methods is of great significance. In the presence of tetramethylguanidine and silver nitrate, 4-hydroxyquinoline-2(1H)-ones were efficiently synthesized from 2-ethynylanilines and carbon dioxide under atmospheric pressure. The reaction conditions, such as types of silver catalysts and reaction solvents, were optimized, and the applicability of the substrate was preliminarily investigated. This method provides an alternative pathway for the synthesis of 4-hydroxyquinoline-2(1H)-ones and the conversion and utilization of carbon dioxide.
研究领域:
有机化学
·
药物化学
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DOI
高影响因子
Materials Today Energy
·
2024
·
IF 9
Songyu Li,Penghui Ren,Di Zhao,Dan Liu,Jianqiao Wang,Hang Zhou,Wei Liu,Yuheng Zeng,Xuegong Yu,Can Cui,Peng Wang
Recently, p-type inorganic copper-based compounds have attracted increasing interest as hole-selective layers for crystalline silicon (c-Si) heterojunction solar cells. Among them, copper(I) thiocyanate (CuSCN) has a small valence band offset with c-Si and high stability, however, it has not been explored in c-Si solar cell applications. Herein, we successfully demonstrate that solution-processed CuSCN film acts as an effective hole-selective contact layer for p-Si solar cells. Nevertheless, the p-Si/CuSCN heterostructure suffers from an unsatisfactory surface passivation and a relatively high contact resistivity originated from the uncontrollable vacancy defects in the film. The I − doping of CuSCN film (CuSCN:I − ) not only suppresses the generation of SCN vacancies, but also increases the Cu vacancies, significantly improving the hole selectivity . Moreover, a better energy band alignment is formed based on CuSCN:I − /MoO 3 bilayer for hole selective contact of p-Si substrate, achieving a remarkably high photoelectric conversion efficiency (PCE) of 19.42 %. The PCEs of unencapsulated p-Si/CuSCN heterojunction solar cells maintain over 92 % of the initial values under storing in air atmosphere for 1200 h or after annealing at 350 °C. This work highlights that CuSCN is a very promising hole selective layer with superior stability for c-Si solar cell applications.
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DOI
高影响因子
NEW JOURNAL OF CHEMISTRY
·
2020
·Vol. 44
·期 33
·14103-14107
·
IF 3.288
Chanchan Xu,Le Lv,Dawei Luo,Wei Liu
By using pyrazine derivatives, three different types of copper(I) iodide based inorganic–organic hybrid structures, 1D-CuI(2-mo-pz) (1, 2-mo-pz = 2-methoxy-pyrazine), 2D-CuI(2,3-dm-pz)0.5 (2, 2,3-dm-pz = 2,3-dimethyl-pyrazine), and 2D-Cu2I2(2,5-dm-pz)2 (3, 2,5-dm-pz = 2,5-dimethyl-pyrazine), have been obtained by using a slow-diffusion method. Single crystal and powder X-ray diffraction analyses reveal that these hybrid structures are a one-dimensional (1D) staircase chain based structure, two-dimensional (2D) staircase-chain based structure, and 2D rhomboid dimer based structure, respectively. All of the three compounds show photoluminescence, with the internal quantum yield (IQY) as high as 88.2% for 1. This work provides evidence that for this type of hybrid materials, the structure of the inorganic module could be determined by the selection of the organic ligands and that the substituted group on the organic ligands can influence the luminescence efficiency of the hybrid structures.
研究领域:
无机化学
·
材料化学
·
配位化学
·
光物理
·
功能材料
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DOI
高影响因子
ACS Nano
·
2015
·
IF 12.881
Feng Zhang,Haizheng Zhong,Cheng Chen,Xian-gang Wu,Xiangmin Hu,Hailong Huang,Junbo Han,Bingsuo Zou,Yuping Dong
Organometal halide perovskites are inexpensive materials with desirable characteristics of color-tunable and narrow-band emissions for lighting and display technology, but they suffer from low photoluminescence quantum yields at low excitation fluencies. Here we developed a ligand-assisted reprecipitation strategy to fabricate brightly luminescent and color-tunable colloidal CH3NH3PbX3 (X = Br, I, Cl) quantum dots with absolute quantum yield up to 70% at room temperature and low excitation fluencies. To illustrate the photoluminescence enhancements in these quantum dots, we conducted comprehensive composition and surface characterizations and determined the time- and temperature-dependent photoluminescence spectra. Comparisons between small-sized CH3NH3PbBr3 quantum dots (average diameter 3.3 nm) and corresponding micrometer-sized bulk particles (2–8 μm) suggest that the intense increased photoluminescence quantum yield originates from the increase of exciton binding energy due to size reduction as well as proper chemical passivations of the Br-rich surface. We further demonstrated wide-color gamut white-light-emitting diodes using green emissive CH3NH3PbBr3 quantum dots and red emissive K2SiF6:Mn4+ as color converters, providing enhanced color quality for display technology. Moreover, colloidal CH3NH3PbX3 quantum dots are expected to exhibit interesting nanoscale excitonic properties and also have other potential applications in lasers, electroluminescence devices, and optical sensors.
研究领域:
材料科学
·
纳米技术
·
光电子学
·
显示技术
·
光子学
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DOI
高影响因子
NEW JOURNAL OF CHEMISTRY
·
2018
·Vol. 42
·期 17
·14332-14339
·
IF 3.201
Nan Zhou,Xingwei Zhang,Yanping Shi,Zeliang Li,Zhibiao Feng
Nitrogen-doped carbon quantum dots (CDs) were synthesized in ethanol media by using citric acid (CA) as the carbon source and ethanediamine (EDA) as the nitrogen source. The obtained CDs were characterized by multiple analytical techniques including high resolution transmission electron microscopy (TEM), X-ray photoelectron spectroscopy (XPS) and Fourier transform infrared spectroscopy (FTIR). The prepared CDs can be constructed as a fluorescent probe for the detection of Hg2+ with good sensitivity and selectivity. Upon addition of I−, the fluorescence can be restored due to the strong interaction between Hg2+ and I−. The fluorescence can also be restored with the addition of Br− by changing the buffer solution. The linear ranges and the limits of detection were 0–20 μM and 65 nM for I−, and 0–28 μM and 98 nM for Br−, respectively. In addition, the UV-vis spectrum of this sensing system was studied to validate the detection mechanism of Hg2+, I− and Br−.
研究领域:
分析化学
·
纳米材料
·
环境监测
·
传感器与生物传感器
·
荧光光谱学
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DOI
高影响因子
危险品化学品经营许可证（带存储）