JOURNAL OF CHROMATOGRAPHY A
·
2022
·
IF 4.601
Meilin Xu,Lunzhao Yi,Dabing Ren,Boyan Li
Citrus flavonoids are attracting great interest due to their well-known beneficial effects, but many of them have not been characterized. In this work, ultra-high liquid chromatography coupled to high resolution mass spectrometry (UHPLC HRMS) was used for profiling flavonoids in citrus fruit. We proposed a strategy combining mass defect filtering (MDF) and MS/MS–based molecular networking (MMN) to handle complex UHPLC–HRMS data. The proposed strategy was explained and validated in the fruit of Citrus sinensis ( L. ) Osbeck, and when specific mass and mass defect windows were pre-defined, MDF enable removal of considerable un-related and/or interference MS 1 peaks. In citrus fruit, the number of MS 1 peaks in positive and negative modes were reduced by 70.80% (from 15,113 to 4413) and 55.30% (from 5617 to 2511), respectively, and thus the potential MS features of flavonoids were retained and exposed. After MDF, an MS/MS similarity-based MMN map was constructed to cluster flavonoids with similar chemical structures. MMN facilitated the annotation of 65 unknown citrus flavonoids by using only 21 pre-identified flavonoids as references. The compounds comprised 42 polymethoxylated flavonoids, 17 flavones, 24 flavanones, and 3 flavonols. Eleven of them had not been previously reported in Citrus sinensis ( L. ) Osbeck to our knowledge. Results of the current work indicated that the combination of MDF and MMN is a useful strategy for removing interference MS 1 peaks and performing the structural annotation of unkonwn compounds in complex samples.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
MICROCHEMICAL JOURNAL
·
2022
·
IF 5.304
Panpan Wang,Junxia Wang,Tingting Liu,Zhengpeng Sun,Ming Gao,Kai Huang,Xuedong Wang
As one kind of high nutrition fruits, abandoned loquat causes great waste due to short storage period. For resource utilization, we herein fabricated the loquat fruit-based carbon quantum dots (CQDs) by a facile/green hydrothermal method. The as-fabricated CQDs showed spherical shape with an average size of 4.46 nm, and richness in functional hydroxyl and carboxyl moieties on their surface. Under daylight and UV light, the as-fabricated CQDs displayed light yellow and blue color, respectively, with a fluorescence quantum yield of 10.36%. Upon the addition of MnO 4 − , the fluorescence intensity of loquat-based CQDs was prominently quenched in a concentration-dependent manner, suggesting the feasibility for constructing a sensitive “ON-OFF” nanoprobe. By virtue of changes in UV-Vis absorption, fluorescence lifetime, Stern-Volmer constant and zeta potential, the MnO 4 − -triggered quenching mechanisms were attributable to the joint action of inner filter effect and static quenching. Under optimized conditions, the CQDs supplied wide linear range of 0.2–150 μM, low detection limit of 0.06 μM, and high recovery of 96.0–106.0% for MnO 4 − in environmental waters. Especially, it exhibited the superior selectivity and anti-inference capacity for other commonly existed cations and anions in waters. In contrast to China authentic indirect iodometry method and previously reported approaches, the newly developed “ON-OFF” nanoprobe possesses comparable or even better analytical performance. As far as our information goes, it is the first report on the loquat fruit-based CQDs for successful application in the assay of trace-level MnO 4 − in environmental waters, thereby showing great potential in conventional monitoring.
✓ 已验证
产品关联
DOI
高影响因子
FOOD CHEMISTRY
·
2026
·
IF 10.4
Lingshuai Meng,Meirun Zhu,Xu Song,Junjie Yi,Guangcan Tao,Siyao Wu,Tingting Zheng,Sen Cao,Su Xu
This study systematically evaluated thermal drying methods effects on characteristic volatile organic compounds of passion fruit peel using E -nose, GC–MS, GC-IMS combined with multivariate statistical analysis. Specifically, GC–MS exhibited higher sensitivity for hydrocarbons and other compounds, whereas GC-IMS was esters, aldehydes, and alcohols. Multiple Factor Analysis confirmed that the combination of these two methods was shown to more comprehensively evaluate the volatile flavor compounds and aroma characteristics of passion fruit peel. Overall, HPD exhibited the best retention of characteristic volatile organic compounds (e.g., Methyl benzoate-M, Nonanal, Decanal), generated new compounds (e.g., (E)-2-octenal, Benzaldehyde, 2-methylbutanal) and enriched the aroma characteristics (e.g., apple, chocolate, fruity). Therefore, HPD was recommended as the optimal pretreatment method for obtaining the best aroma quality of passion fruit peel. Besides, methyl benzoate could serve as a key marker for evaluating the aroma quality of passion fruit peel dried by VMD.
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF CHROMATOGRAPHY A
·
2020
·
IF 4.049
Zhixu Chen,Qi Li,Taicheng Yang,Yaofeng Zhang,Minhong He,Huiyun Zeng,Xiaoman Mai,Yingtao Liu,Huajun Fan
A simple, green and efficient method for extraction, purification and enrichment of pesticide residues of triazoles and pyrethroids in Longan fruit was developed by ultrasonic-assisted aqueous two-phase extraction (UAATPE) coupled to vortex-assisted dispersive liquid-liquid microextraction (VADLLME). Using an aqueous two-phase system (ATPS) of ethanol/K 2 HPO 4 as extraction solvent, the composition of the ATPS, extraction temperature and time were investigated, respectively. Then VADLLME process also was optimized by investigating type and volume of extracting and dispersive solvents, vortex-assisted time and salt addition. The optimum conditions were as follows: the ATPS composition of ethanol concentration 30.0% (w/w) and K 2 HPO 4 concentration 25% (w/w), extraction temperature 70 °C and extraction time 15 min for UAATPE; 1-dodecanol 200 μL as extraction solvent, ethanol 1.25 mL as dispersive solvent, vortex-assisted time 1.5 min and addition of NaCl 4% (w/v) for VADLLME. Ethanol as extraction solvent and dispersive solvent could directly connect UAATPE with VADLLME without extra steps. By means of HPLC-DAD detection, nine pesticides had good linearity ranged from 0.0200 to 13.59 μg/mL (R 2 ≥ 0.9957). LODs and LOQs were in the range of 0.005576−0.01740 μg/mL and 0.01859−0.05010 μg/mL, respectively. UAATPE-VADLLME coupled to HPLC was successfully applied to simultaneous determination of multiple pesticides in Longan fruit, and mean recoveries and RSDs were between 76.95% and 98.63%, 1.2% and 9.8%, respectively. Furthermore, myclobutanil, fenpropathrin and deltamethrin were detected in pericarp and pulp of Longan samples from different districts, respectively.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ANALYTICA CHIMICA ACTA
·
2022
·
IF 6.911
Hanlong Yan,Guo Zhao,Wei Lu,Can Hu,Xiaochan Wang,Gang Liu,Ning Shi,Nguyen Thi Dieu Thuy,Litao Zhang
This study developed a flexible and wearable paper-based chemoresistive sensor (FWPCS) by modifying a SWCNT-PdNP-polystyrene microsphere (SPPM) composite (SPPM/FWPCS) for the low-cost and online determination of fruit ripeness and corruption. A new method for the batch and low-cost fabrication of SPPM/FWPCSs based on laser direct writing was proposed. The sensing mechanism of FWPCS relies on the electron depletion layer in the sensing composite created by the Schottky barriers among SWCNTs, PdNPs, and the adsorbed oxygen, along with the construction of O 2 − . When the SPPM sensing film is exposed to ethylene, trapped electrons are released into the conduction band through oxidation and cleavage of ethylene, causing a decrease in resistance. The properties and morphology of the synthesized SPPM composite were investigated by X-ray diffraction (XRD), scanning electron microscopy (SEM), transmission electron microscopy (TEM), and Raman spectroscopy . Additionally, the key parameters for the fabrication of SPPMs/FWPCS related to the sensing performance were optimized. The concentration of C 2 H 4 can be detected down to 100 ppb using the SPPMs/FWPCS at 25 °C. Finally, the real-time determination of banana ripeness and corruption verified the feasibility of the sensor, indicating that the SPPMs/FWPCS has prospects in monitoring fruit ripeness and corruption during storage and transportation.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Journal of Physical Chemistry C
·
2023
·
IF 3.7
Nguyen Ngoc Huyen,Le Minh Tung,Tuan Anh Nguyen,Thi Lan Huong Phung,Pham Duc Thang,Nguyen Thanh Vinh,Quy Van Nguyen,Thi Kim Oanh Vu,Vu Dinh Lam,Vinh Khanh Le,Ngo Xuan Dinh,Anh-Tuan Le
The recent advancement in designing novel spinel nanostructures has opened virtually infinite possibilities for the development of high-performance electrochemical sensors to detect target species. The electrocatalytic activity of spinel structures can be enhanced by tuning the cation distribution; however, the role of cation distribution at tetrahedral ions on the electrochemical sensing responses has rarely been considered. Herein, the effect of cation distribution at tetrahedral sites (Td) in the spinel nanostructure ZnCo2O4 on the electrochemical sensing performance toward carbaryl (CBR) was first investigated. The ZnCo2O4 nanoflake samples with different cation ratios of Zn/Co at tetrahedral sites were designed by using a facile solvothermal method. We found that a higher Zn ion content at tetrahedral sites significantly enhanced the electron transfer ability through the electrolyte/electrode interface. More interestingly, a higher Co ion ratio between octahedral sites and tetrahedral (CoOh/CoTd) promoted the electrochemical oxidation process of CBR with a higher catalytic rate constant (kcat). Under optimized conditions, the ZnCo2O4-NF-based electrochemical nanosensor showed a linear response from 0.15 to 100 μM with a limit of detection of 0.05 μM and a high electrochemical sensitivity of 2.04 μA μM–1cm–2. The designed nanosensor also exhibited good repeatability, long-time stability, high anti-interference ability, and excellent recovery with fruit and vegetable samples. Furthermore, this study offers insights into the cation distribution-dependent electrocatalytic activities of spinel nanostructures, which is helpful to the design of advanced spinel nanostructure-based electrocatalysts for improving the electrochemical sensing performance.
✓ 已验证
DOI
高影响因子
JOURNAL OF CHROMATOGRAPHY A
·
2017
·
IF 3.981
Linna You,Man He,Beibei Chen,Bin Hu
In this work, zeolitic imidazolate framework-8 (ZIF-8)/poly (methyl methacrylate-ethyleneglycol dimethacrylate) (MMA-EGDMA) composite monolith was in situ synthesized on stir bar by one-pot polymerization. Compared with the neat monolith, ZIF-8/poly(MMA-EGDMA) composite monolith has larger surface area and pore volume. It also exhibits higher extraction efficiency for target phytohormones than poly(MMA-EGDMA) monolith and commercial polyethylene glycol (PEG) coated stir bar. Based on it, a method of ZIF-8/poly(MMA-EGDMA) monolith coated stir bar sorptive extraction (SBSE)-high performance liquid chromatography-ultraviolet detection (HPLC-UV) was established for the analysis of five phytohormones in apple and pear samples. The developed method exhibited low limits of detection (0.11–0.51 μg/L), wide linear range (0.5–500 μg/L) and good recoveries (82.7–111%), which demonstrated good application potential of the ZIF-8/monolith coated stir bar in trace analysis of organic compounds.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
CHIRALITY
·
2022
·Vol. 34
·期 7
·968-976
·
IF 2.183
Haijuan Jiang,Xin Huang,Haoyue Xue,Min Wang,Yanli Qi,Liyan Jia,Xu Jing
A switchable deep eutectic solvent-based homogeneous liquid–liquid microextraction (SDES-HLLME) technique was developed and combined with high-performance liquid chromatography–diode-array detection for the determination of the chiral fungicide mefentrifluconazole. A (green) SDES was synthesized from 4-methoxyphenyl and 3-amino-1-propanol and used as an extraction solvent (thus avoiding the use of toxic extraction solvents). To improve the efficiency of the extraction process, a hydrophobic extraction solvent was subsequently generated in situ by adjusting the pH. The detection process is linear in the range of 0.01 to 1 μg ml −1 . The limit of detection and limit of quantification were determined to be 0.003 and 0.01 μg ml −1 , respectively. Recovery rates of 79.2% to 104.6% were acquired with relative standard deviations of 0.6% to 2.5%. The method is fast, simple, and environmentally friendly. Moreover, it was successfully used to enantioselectively determine the concentrations of mefentrifluconazole residues in water, fruit juice, and fermented liquor samples.
✓ 已验证
DOI
高影响因子
TALANTA
·
2017
·
IF 4.162
Xiaoling Yang,Kexin Qiao,Fang Liu,Xiaoling Wu,Miyi Yang,Jing Li,Haixiang Gao,Sanbing Zhang,Wenfeng zhou,Runhua Lu
In this research, a novel method using magnetic mixed hemimicelles dispersive solid-phase extraction (MMHDSPE) based on C 16 mimBr-coated attapulgite/polyaniline-polypyrrole/Fe 3 O 4 (ATP/PANI-PPY/Fe 3 O 4 ) nanocomposites were investigated for enrichment and separation of three acaricides in fruit juice. In this method, we combined the simplicity and speed of dispersive solid-phase extraction, the advantages of mixed hemimicelles and the facility of the phase separation of the magnetic nanoparticles to develop a simple, rapid, sensitive, and effective method for detecting target analytes from the juice samples. ATP/PANI-PPY/Fe 3 O 4 nanocomposites were successfully synthesized using a one-pot method. The as-prepared nanocomposite sorbents were characterized by Fourier transform infrared spectra (FT-IR), X-ray diffraction (XRD), scanning electron microscopy (SEM), and transmission electron microscopy (TEM). The experimental factors affecting the extraction efficiency including the sorbent type, amount of ATP/PANI-PPY/Fe 3 O 4 nanocomposites, volume of ILs , sonication time, pH, and desorption conditions were optimized. Under the optimal conditions, good linearity was observed for all target analytes, with correlation coefficients (r 2 ) ranging from 0.9994 to 0.9999; the limits of detection (LOD) were in the range of 0.16–0.57 μg L −1 , and the recoveries of analytes using the proposed method ranged between 88.67% and 95.10%. The sorbents exhibited excellent repeatability in the range of 1.83–4.24% in extracting the three target analytes. In addition, the intra-day and inter-day precision values were found to be in the range of 0.19–6.24% and 2.23–8.36%, respectively. The method was successfully applied to analyze fruit juice samples by rapid preconcentration of acaricides.
✓ 已验证
DOI
高影响因子
JOURNAL OF FOOD COMPOSITION AND ANALYSIS
·
2023
·
IF 4.3
Mohammad Nazari Kalojeh,Roghayeh Hassanpour Sabet,Mir Ali Farajzadeh,Mohammad Reza Afshar Mogaddam,Elnaz Marzi Khosrowshahi,Mustafa Tuzen
A dispersive solid phase extraction procedure was established for the extraction of some pesticides from fruit juices and then it was combined with dispersive liquid-liquid microextraction for more enrichment of the analytes. For this purpose, 40 mg of zeolitic imidazolate framework-carbon dot composite was dispersed into the sample solution as the sorbent via vortex agitation. After that, the sorbent was collected by centrifugation and the supernatant was wasted. Then, 1 mL of a water-soluble organic solvent (acetone) was added onto the sorbent as the elution solvent. After desorption of the analytes from the sorbent surface, the eluate was mixed with a water-immiscible organic solvent (1,1,2-trichloro-1,2,2 trifluoroethane) at µL-level (45 µL) and the mixture was quickly injected into 5 mL deionized water. The resulting cloudy mixture was centrifuged and 1 µL of the sedimented phase was injected into a gas chromatography-flame ionization detection system. After the optimization of the method, its validation was evaluated. The data showed that the limits of detection and quantification obtained by this method were in the ranges of 0.22–0.72 and 0.73–2.40 ng mL −1 , respectively. The plotted calibration curves were linear in the range of 0.73–1000 µg L −1 for all analytes. High enrichment factors (375−445), and extraction recoveries (75–89%), and negligible matrices effect were obtained for the investigated analytes by the introduced method. Also, the obtained data showed that all samples were free of the analytes.
✓ 已验证
DOI
高影响因子
Pharmacognosy Magazine
·
2017
·
IF 1.069
Feng Shao,Lifei Gu,Huijuan Chen,Ronghua Liu,Huilian Huang,Lanying Chen,Ming Yang
Background: Hawthorn ( Crataegus pinnatifida ) fruit has enjoyed a great popularity as a pleasant-tasting food associated with hypolipidemic and antioxidant effects. Objective: Our aim was to screen the effective fraction of hawthorn fruit in the treatment of hyperlipidemia rats. Materials and Methods: In this study, ethanol extract of hawthorn fruit (Fr.1) and four fractionated extracts (Fr.2, Fr.3, Fr.4, and Fr.5) were compared to total phenol content evaluated using Folin–Ciocalteu method, and hypolipidemic and antioxidant effects were assessed in hyperlipidemic rats. Results: Total phenol content of Fr.4 was higher than other fractions by at least 2 fold. Furthermore, this fraction possessed the strongest hypolipidemic and antioxidant effects in hyperlipidemic rats. On this basis, 15 phenolic compounds and four organic acids in Fr.4 were positively or tentatively identified using ultra-performance liquid chromatography coupled with quadropole time-of-flight mass spectrometry. In addition, 5-O-caffeoyl quinic acid butyl ester was first reported in hawthorn fruit. Conclusion: Phenol-rich fraction in hawthorn fruit exhibited satisfactory hypolipidemic and antioxidant effects, and this could be exploited for further promotion of functional foods. SUMMARY Phenol-rich fraction in hawthorn fruit possesses most potent hypolipidemic and antioxidant effects in hyperlidemia rats. Abbreviations used: UPLC-Q-TOF-MS/MS: Ultra performance liquid chromatography coupled with quadropole time-of-flight mass spectrometry; TC: Total cholesterol; TG: Triglyceride; LDL-C: Low-density lipoprotein-cholesterol; HDL-C: High-density lipoprotein-cholesterol; GSH-Px: Glutathione peroxidase; SOD: Superoxide dismutase; MDA: Malondialdehyde; CAT: Catalase; NO: Nitric oxide; NOS: Nitric oxide synthase; ROS: Reactive oxygen species; •OOH: Superoxide anions, •OH: Hydroxyl radicals.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）