Journal of Environmental Chemical Engineering
·
2025
·
IF 7.2
Weirui Chen,Weijie Chen,Yimin Luo,Yanqi Feng,Xukai Li,Jing Wang,Ping Li,Liying Bin,Bing Tang,Laisheng Li
g-C 3 N 4 (CN) based catalysts were effective for photocatalytic ozonation (PCO), but their stability during reaction remained a mystery. This study investigated the change on PCO activity and stability of CN induced by F or I doping. Compared with CN, F-CN had the greater VB potential while I-CN had a greater CB position, which both led to their better O 3 activation. F-CN and I-CN PCO showed the greater oxalic acid (OA) degradation than that of CN PCO process. Though the enhanced activity, both F-CN and I-CN demonstrated the lower stability compared with that of CN. Because of the existing of reactive oxygen species (ROS) like •OH, •O 2 - and h vb + , CN, F-CN and I-CN were partially oxidized, generating NO 3 - and organic molecules such as cyanuric acid. h vb + and •OH mainly accounted for the decomposition of three CN. Triazine ring oxidation resulted in internal tearing and edge fracture as well as the formation of O-containing groups on all CN-based catalysts. O contents in catalysts initially increased and then decreased with reaction time, indicating that surface O-containing groups were unstable. The structural destroy could be eased with the present of organic pollutants. This study deepened the understanding of fate of CN based catalysts during PCO application.
✓ 已验证
产品关联
DOI
高影响因子
Inorganic Chemistry Frontiers
·
2024
·
IF 6.1
Zhiyuan Li,Xiangjun Wang,Peng Zhao,Jingquan Liu,Xiangxin Tian
Two-dimensional perovskites have demonstrated superior application prospects in optoelectronic fields, such as X-ray detection, light emitting diodes, and photovoltaics, as their tunability of band structures, improved stability, fast responses, and suppressed noise signal. In this work, bulk single crystals of MA3Bi2Br9 (MA+=CH3NH3+) and its two mixed crystal MA3Bi2(Br0.74I0.26)9, MA3Bi2(Br0.62I0.38)9 were successfully grown using the bottom-seeded solution growth method. MA3Bi2I9 crystals were also prepared and characterized for comparisons. X-ray diffraction analysis revealed that all the crystals had quasi-two-dimensional (2D) structures and the partial substitution of I- for Br- did not alter the space group symmetry. However, with the increase of I- concentrations, the incongruently melting temperature gradually decreased from 342 oC for MA3Bi2Br9 to 328 oC for MA3Bi2(Br0.62I0.38)9, respectively. For optoelectronic properties, the MA3Bi2Br9 was measured to have a direct bandgap of 2.60 eV, while the values decreased to 2.15 eV for MA3Bi2(Br0.74I0.26)9, 2.04 eV for MA3Bi2(Br0.62I0.38)9, and 1.97 eV for MA3Bi2I9, respectively. Similarly, the photoluminescence peaks blue-shifted from 550 nm for MA3Bi2Br9, to 453 nm for MA3Bi2(Br0.74I0.26)9, 445 nm for MA3Bi2(Br0.62I0.38)9, and 444 nm for MA3Bi2I9, respectively. Due to the strong dielectric confinement effects and anisotropic exciton transportation characteristics of the 2D structures, the targeted crystals studied all exhibited ultrafast fluorescence decay characteristics, where decay time as short as 0.65 ns the sub-nanosecond, for MA3Bi2Br9, 1.06 ns for MA3Bi2(Br0.74I0.26)9, 3.00 ns for MA3Bi2(Br0.62I0.38)9, and 3.12 ns for MA3Bi2I9, respectively, were observed. Besides, the low dimensional structures also brought the crystals superior environmental stability as the suppressed ion migrations. This work provides simple, straightforward method for the large-sized crystal growth of low dimensional MA3Bi2X9 (X-=Br-, I-), and reveals their promising application prospects in novel optoelectronic fields.
✓ 已验证
产品关联
DOI
高影响因子
TALANTA
·
2024
·
IF 5.6
Wei Zhang,Jidong Jiang,Tao Liu,Xun Wang,Wei Zhang,Yiqing Wang,Zhenyu Chu,Wanqin Jin
Acute myocardial infarction (AMI) is a life-threatening disease with a short course and a high mortality rate. However, it is still a great challenge to achieve the on-site diagnosis of this disease within minutes, meaning there is an urgent need to develop an efficient technology for realizing the rapid diagnosis and early warning of AMI in clinical emergencies. In this study, an ultrasensitive electrochemical aptasensor based on an extended-gate ion-sensitive field-effect transistor (EGISFET) was designed to achieve the quantitative assay of cardiac troponin I (cTnI), which is a highly sensitive and specific biomarker of AMI, within only 5 min. The EGISFET exhibits extremely high detection sensitivity due to its separated structure with a large sensing area and the surface-modified Prussian blue-gold nanoparticles (PB-AuNPs) composite, which serves as a signal magnifier and DNA loading platform for good electrocatalytic ability with a large specific area. Additionally, a target-induced strand-release strategy is proposed to shorten the recognition time of cTnI using a particular DNA strand. Under optimal conditions, the as-prepared aptasensor exhibits a wide linear range of 1–1000 pg/mL, an ultralow detection limit of 0.3 pg/mL, and reliable detection results in real serum samples. It is highly anticipated that this EGISFET-based aptasensor will have broad applications in the early warning and rapid diagnosis of AMI and other acute diseases in emergency treatment.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
PHYTOMEDICINE
·
2024
·
IF 6.7
Sheng Zhang,Rongrong Huang,Junsong Jing,Xueping Wei,Yu Zhang,Youping Wu,Guoteng Ou,Jingjin Hu,Yueguo Wu,Yuanyuan Li,Shibo Ying,Zhenqiang You
ABSTRACT Background Acute respiratory distress syndrome (ARDS) is an acute respiratory disease characterized by bilateral chest radiolucency and severe hypoxemia. Quzhou Fructus Aurantii ethyl acetate extract (QFAEE), which is prepared from the traditional Chinese respiratory anti-inflammatory natural herb Quzhou Fructus Arantii, has the potential to alleviate ARDS. In this work, we aimed to investigate the potential and mechanism underlying the action of QFAEE on ARDS and how QFAEE modulates the STING pathway to reduce type I interferon release to alleviate the inflammatory response. Methods Lipopolysaccharide (LPS), a potential proinflammatory stimulant capable of causing pulmonary inflammation with edema after nasal drops, was employed to model ARDS in vitro and in vivo . Under QFAEE intervention, the mechanism of action of QFAEE to alleviate ARDS was explored in this study. TREX1 −/− mice were sued as a research model for the activation of the congenital STING signaling pathway. The effect of QFAEE on TREX1 −/− mice could explain the STING-targeted effect of QFAEE on alleviating the inflammatory response. Our explorations covered several techniques, Western blot, histological assays, immunofluorescence staining, transcriptomic assays and qRT-PCR to determine the potential mechanism of action of QFAEE in antagonizing the inflammatory response in the lungs, as well as the mechanism of action of QFAEE in targeting the STING signaling pathway to regulate the release of type I interferon. Results QFAEE effectively alleviates ARDS symptoms in LPS-induced ARDS. We revealed that the mechanism underlying LPS-induced ARDS is the STING-TBK1 signaling pathway and further elucidated the molecular mechanism of QFAEE in the prevention and treatment of ARDS. QFAEE reduced the release of type I interferons by inhibiting the STING-TBK1-IRF3 axis, thus alleviating LPS-induced pneumonia and lung cell death in mice. Another key finding is that activation of the STING pathway by activators or targeted knockdown of the TREX1 gene can also induce ARDS. As expected, QFAEE was found to be an effective protective agent in alleviating ARDS and the antagonistic effect of QFAEE on ARDS was achieved by inhibiting the STING signaling pathway. Conclusions The main anti-inflammatory effect of QFAEE was achieved by inhibiting the STING signaling pathway and reducing the release of type I interferons. According to this mechanism of effect, QFAEE can effectively alleviate ARDS and can be considered a potential therapeutic agent. In addition, the STING pathway plays an essential role in the development and progression of ARDS, and it is a potential target for ARDS therapy.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Nanomaterials
·
2024
·Vol. 14
·期 19
·1579
·
IF 4.4
Liying Jiang,Dongyang Li,Mingxing Su,Yirong Qiu,Fenghua Chen,Xiaomei Qin,Lan Wang,Yanghai Gui,Jianbo Zhao,Huishi Guo,Xiaoyun Qin,Zhen Zhang
Cardiac troponin I (cTnI) monitoring is of great value in the clinical diagnosis of acute myocardial infarction (AMI). In this paper, a highly sensitive electrochemical aptamer sensor using polystyrene (PS) microspheres as the electrode substrate material in combination with Prussian blue (PB) and gold nanoparticles (AuNPs) was demonstrated for the sensitive and label-free determination of cTnI. PS microspheres were synthesized by emulsion polymerization and then dropped onto the glassy carbon electrode (GCE); PB and AuNPs were electrodeposited on the electrode in corresponding electrolyte solutions step by step. The PS microsphere substrate provided a large surface area for the loading mass of the biological affinity aptamers, while the PB layer improved the electrical conductivity of the modified electrode, and the electroactive AuNPs exhibited excellent catalytic performance for the subsequent electrochemical measurements. In view of the above mentioned AuNPs/PB/PS/GCE sensing platform, the fabricated label-free electrochemical aptamer sensor exhibited a wide detection range of 10 fg/mL~1.0 μg/mL and a low detection limit of 2.03 fg/mL under the optimal conditions. Furthermore, this biosensor provided an effective detection platform for the analysis of cTnI in serum samples. The introduction of this sensitive electrochemical aptamer sensor provides a reference for clinically sensitive detection of cTnI.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
·
2017
·
IF 3.359
Fuyin Ma,Zheng Li,Haogui Zhao,Yiyun Geng,Wei Zhou,Qingnuan Li,Lan Zhang
As a new carbon-based membrane material used for ionic and molecular sieving, the graphene oxide (GO) membrane also has potential application in radiochemical separation. In this work, the permeation performances of some typical metallic elements in high level-liquid waste (HLLW) through the ionic sieving 5-μm-thick GO membranes were investigated. It was found that the permeation rates of ions through GO membranes markedly decreased with the increase of hydrated ionic radii. Cs(I) and Sr(II) permeated through GO membranes quickly, whereas lanthanide ions and actinide ions infiltrated much more slowly, thus providing the feasibility of separation according to the difference of hydrated ionic radii. Moreover, the concentrations of initial metal ions and acidity in feed solutions also had influences on the permeation of ions through GO membranes, and higher initial metal ions and feed solution acidity were favorable to the removal of Cs(I) and Sr(II). The barrier separation test indicated that GO membranes had promising ability for the separation of Cs(I) and Sr(II) from lanthanide and actinide ions due to the difference of hydrated ion radius, and the separation factor of Cs(I)/U(VI) and Sr(II)/U(VI) would reach about 10 and 3 in single penetration. The presented results demonstrated that the membrane separation based on GO membrane would be a promising candidate for the removal of Cs(I) and Sr(II) from HLLW.
✓ 已验证
产品关联
DOI
高影响因子
RSC Advances
·
2017
·Vol. 7
·期 11
·6605-6614
·
IF 3.108
Ce Gao,Qingda An,Zuoyi Xiao,Shangru Zhai
Nowadays, processing of ultra-low sulfur fuel oil has been a hot topic of research all over the world; hence, an efficient adsorption process to tackle this issue is eliciting increasing attention. However, the preparation of high-performance adsorbents is still a challenge. Herein, zirconium-substituted mesoporous SBA-15 with highly dispersed active Cu(I) species has been successfully synthesized by our group at 493 K via a mild vapor-reduction method. The as-prepared material was characterized by powder X-ray diffraction (XRD), nitrogen adsorption and desorption, scanning electron microscopy (SEM), transmission electron microscopy (TEM), and UV-vis diffuse reflectance (DRUV) spectroscopy. All characterization methods demonstrated that the Cu(I) species were highly dispersed in an ordered mesoporous framework with short channels rather than piled on the surface. The as-prepared materials also exhibited an excellent adsorption capacity for thiophene (up to 29.86 mg g−1 at 323 K). Pseudo-second-order kinetics model and Freundlich isotherm can well describe the adsorption kinetics and isotherm data, respectively. More remarkably, an ultrasound-assisted treatment can be effectively employed to regenerate adsorbent, with only a slight reduction in the adsorption capacity after five cycles.
✓ 已验证
DOI
高影响因子
JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY
·
2016
·Vol. 92
·期 4
·819-826
·
IF 2.738
Xiao Liang,Ying Ge,Zhenglong Wu,Weidong Qin
BACKGROUND Hg(II) and MeHg(I) are toxic pollutants causing wide concerns. Polyamidoamine-grafted magnetic silica nanoparticles (Fe 3 O 4 -SiO 2 -PAMAMs) were synthesized as beads, on which herring sperm DNA fragments were immobilized as reacting moieties for removal of Hg(II) and MeHg(I) from water matrices. The factors influencing the removal, such as DNA fragments, generation of the polyamidoamine spacers and pH, were studied. Further, the adsorption mechanisms were explored by means of adsorption kinetics and isotherms. RESULTS Assembling DNA fragments on the polyamidoamine-grafted beads promoted sharply the removal of both Hg(II) and MeHg(I). Adsorptions of Hg(II) and MeHg(I) followed pseudo-second-order kinetics; but their adsorption isotherms obeyed Langmuir and Freundlich models, respectively. Under the optimum conditions, the adsorption equilibrium time was approximately 5 min for Hg(II) and 5 s for MeHg(I) with maximum percentage removals of ∼95% and ∼90%, respectively. The adsorbent could be regenerated easily without significant decrease in removal efficiencies. CONCLUSION The Fe 3 O 4 -SiO 2 -PAMAM beads could bind DNA steadily, and the DNA fragments interacted strongly with mercury species. The strategy enabled the water-soluble DNAs to work as efficient removing reagents for rapid and cost-effective removal of Hg(II) and MeHg(I). © 2016 Society of Chemical Industry
✓ 已验证
产品关联
DOI
高影响因子
Energy & Environmental Science
·
2016
·Vol. 9
·期 12
·3736-3745
·
IF 25.427
Haihua Wu,Haobo Li,Xinfei Zhao,Qingfei Liu,Jing Wang,Jianping Xiao,Songhai Xie,Rui Si,Fan Yang,Shu Miao,Xiaoguang Guo,Guoxiong Wang,Xinhe Bao
A coordinatively unsaturated copper–nitrogen architecture in copper metalloenzymes is essential for its capability to catalyze the oxygen reduction reaction (ORR). However, the stabilization of analogous active sites in realistic catalysts remains a key challenge. Herein, we report a facile route to synthesize highly doped and exposed copper(I)–nitrogen (Cu(I)–N) active sites within graphene (Cu–N©C) by pyrolysis of coordinatively saturated copper phthalocyanine, which is inert for the ORR, together with dicyandiamide. Cu(I)–N is identified as the active site for catalyzing the ORR by combining physicochemical and electrochemical studies, as well as density function theory calculations. The graphene matrix could stabilize the high density of Cu(I)–N active sites with a copper loading higher than 8.5 wt%, while acting as the electron-conducting path. The ORR activity increases with the specific surface area of the Cu–N©C catalysts due to more exposed Cu(I)–N active sites. The optimum Cu–N©C catalyst demonstrates a high ORR activity and stability, as well as an excellent performance and stability in zinc–air batteries with ultralow catalyst loading.
✓ 已验证
产品关联
DOI
高影响因子
INORGANIC CHEMISTRY
·
2014
·
IF 4.794
Jun-Feng Liu,Xue Min,Jin-Yu Lv,Fu-Xing Pan,Qing-Jiang Pan,Zhong-Ming Sun
A family of di-, tri-, and tetranuclear copper(I) complexes supported by length-controlled silaamidinate ligands have been synthesized to show short CuI–CuI distances (2.43–2.62 Å) and feature a linear or bent metal–metal arrangement, which is elucidated by a relativistic density functional theory calculation.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2013
·
IF 3.172
Guangfang Li,Fan Qin,Runming Wang,Shengqiang Xiao,Hongzhe Sun,Rong Chen
A facile microwave irradiation method has been successfully developed for the controllable fabrication of BiOX (X = Cl, Br, I) nanostructures in mannitol solution. The morphology and size of BiOX nanostructures could be readily tailored by adjusting the amount of halide, reaction precursor, and mannitol concentration. Mannitol molecule acts as both a capping agent and a cohesive agent in the formation of BiOX nanostructures. A possible two-stage formation mechanism was discussed based on the morphology evolution of BiOI nanostructures obtained in mannitol solution with different concentrations. The as-synthesized BiOX nanostructures exhibit much higher photocatalytic activities than that of commercial TiO 2 . In particular, flower-like BiOX hierarchical nanostructures display the best photocatalytic performance, which is mainly ascribed to their unique hierarchical structure, high BET surface area, and large band gap. Moreover, BiOX nanostructures also demonstrate superior Cr(VI) removal capacity. The Cr(VI) adsorption behavior was also analyzed by the Langmuir and Freundlich adsorption isotherms.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
·
2025
·
IF 5.4
Jiayun Cheng,Shufen Ren,Hanping Fu,Qing Zhang,Yan Xie,Qingshuang Liang,Xiufeng Xiao
Improving radiation effect and reducing radiation resistance is the key issue to boost the effectiveness of radiotherapy. Herein, we have developed a novel BiOBr 0.5 I 0.5 -BP heterojunction nanosheets (BOBI-BP NSs) for synergistic radiodynamic and photothermal therapy to enhance the efficacy of low-dose radiotherapy under hypoxic conditions. On one hand, this BOBI-BP heterojunction is rich in high-Z elements (Bi, I) and able to deposit high radiation doses into cancer cells, enhancing the radiotherapy effect. On the other hand, due to the heterojunction structure, a large number of electron-hole pairs can be generated and separated under X-ray trigger, which significantly improves the catalytic activity of catalyzing the overexpressed H 2 O 2 in cancer cells into highly toxic •OH, overcoming the oxygen dependence. 1 O 2 could be generated because of the unique sub-band structures of BP NSs and the synergistic effect between BOBI and BP, thereby improving the therapeutic utility of low-dose X-ray irradiation. The synergistic utility of BOBI-BP NSs as a combination of radiodynamic therapy, photothermal therapy agent and radiosensitizer was demonstrated both in vitro and in vivo. This work provides the idea to develop rational designed heterostructures as efficient therapeutic nanoplatform for cancer treatment.
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）