Cell Reports
·
2025
·
IF 6.9
Yiyi Guo,Yuanbin Zhang,Yuanyuan Li,Jie Liu,Yiyang Hu,Jiazhi Jiang,Qi Li,Yeke Chen,Weizhen Hu,Lixi Jiang,Ronghui Pan,Dezhi Wu,Jie Dong
Submergence poses a deleterious threat to plant development and the agricultural production of Brassica napus ( B. napus ), an important worldwide oil crop. However, the molecular mechanisms underlying submergence tolerance in B. napus remain elusive. Here, through a genome-wide association study, we identify a SOMATIC EMBRYOGENESIS RECEPTOR-LIKE KINASE, BKK1/BAK7, which is crucial for plant survival after submergence stress. Submergence rapidly activates the expression of BAK7 and induces the accumulation of its kinase domain in the nucleus. BAK7 interacts with and phosphorylates class I TEOSINTE BRANCHED1, CYCLOIDEA, PROLIFERATING CELL FACTOR 1 and 2 (TCP) transcription factor TCP21, thereby stabilizing it and modulating transcriptomic reprogramming after submergence. Moreover, overexpression of TCP21 rescues the submergence-intolerant phenotype of the bak1-3 bkk1-1 mutant. Interestingly, TCP21 directly binds to the promoter regions of BAK7 to activate its expression after submergence. This study provides insights into the molecular mechanism of plant adaptation to submergence stress and offers promising solutions for breeding submergence-resistant B. napus accessions.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
APPLIED SURFACE SCIENCE
·
2025
·
IF 6.9
Guanzheng Wang,Xiaoli Zhan,Wenjiang He,Zhentao Yuan,Lu Li,Xiao Wang,Wenshen Tang,Zhaolin Zhan
The electronic conductivity of TiO 2 -based anodes was improved fundamentally by co-integrating the oxygen vacancy of TiO 2 into the homogeneous structure with cobalt doping. The results showed that the introduction of oxygen vacancies and Co expanded the lattice space, reduced the charge transfer resistance, and effectively increased the electronic conductivity and ionic transport. Density functional theory (DFT) calculations illustrated that Co doping resulted in a continuous distribution of electronic states at the Fermi energy level, which permitted the sample Co-A/R-TiO 2 to have enhanced metallic properties. The presence of abundant grain boundaries, interfacial and vacancy defects in the hollow microsphere anode all served as additional active sites for Li + storage. The Co-A/R-TiO 2 anode had a high reversible specific capacity of 443 mAh/g after 500 cycles at 0.5 C current density. The high capacity was mainly attributed to the synergistic effect of the perfect defect structure of the hollow spheres and the heterogeneous interfaces. This strategy of using defects combined with homo/heterojunction engineering could be extended to the design of other conventional semiconductor materials as energy storage electrodes.
✓ 已验证
产品关联
DOI
高影响因子
Journal of Energy Storage
·
2025
·
IF 9.8
Guanzheng Wang,Xiaoli Zhan,Wenjiang He,Wenshen Tang,Zhentao Yuan,Lu Li,Xiao Wang,Zhaolin Zhan
Titania (TiO 2 ) is widely recognized as an intercalation-type anode material with favorable parameters of low cost, abundant reserves, high safety, and long life. However, electrode kinetics within TiO 2 is limited, resulting in a theoretical capacity below 335 mAh g −1 . Here, CoTiO 3 was fused with anatase (A)/rutile (R) biphasic TiO 2 to construct multi-scale hybrid CoTiO 3 /A/R-TiO 2 –2 hollow microspheres with a TiO 2 content of about 90 % in this work. The average particle size of the CoTiO 3 /A/R-TiO 2 –2 anode was about 1.97 μm, with a high specific surface area of 76.67 m 2 g −1 , a pore volume of 0.16 cm 3 g −1 , and a large pore size of 8.55 nm. When deployed as an anode in a lithium-ion battery, it provided a high reversible specific capacity of 455 mAh g −1 after 500 cycles at 0.5C. After repeated charge/discharge cycles, a solid electrolyte interphase (SEI) film rich in conducting LiF was formed on the surface of the electrode. Therefore, the high capacity of the anode was mainly attributed to the stable multi-scale hybrid CoTiO 3 /A/R-TiO 2 hollow microspheres and the thin, uniform SEI film. This strategy provided a viable solution for the design of long-life, high-capacity conventional oxide semiconductor anodes.
✓ 已验证
产品关联
DOI
高影响因子
ENERGY
·
2025
·
IF 9.4
Ruihan Dong,Ziyue Tang,Yingquan Chen,Xianhua Wang,Wei Cheng,Qiang Hu,Shusheng Pang,Haiping Yang,Hanping Chen
This study proposes a novel and sustainable approach for the catalytic pyrolysis of microalgae to produce monocyclic aromatic hydrocarbons (MAHs) via algae-based modified biochar catalysts with variant porosity and N content. The effects of introducing of different activators (KOH, KHCO 3 , CH 3 COOK, K 2 CO 3 ) on the physicochemical properties and catalytic performance of the catalysts were systematically investigated. The results indicated that the addition of the activators enhances the specific surface area, porosity, and the abundance of O-/N-containing functional groups with catalytic activity in the biochar catalyst, thereby significantly enhancing the performance of catalyst. Among them, SAC-KOH exhibited a superior porous structure and catalytic effect. The modified biochar catalysts markedly promoted MAHs formation, with benzene, toluene, and xylene identified as the major products. With the addition of the SAC-KOH catalyst, the total relative content of benzene, toluene, and xylene can increase from 8.16 % to 36.53 %. Furthermore, to gain deeper insight into the catalytic conversion mechanism of microalgae to MAHs using modified biochar catalysts, the product transition pathway was explored in depth and comprehensively with soybean protein, sucrose, and peanut oil as the main model compounds of microalgae. These findings demonstrate the feasibility and effectiveness of modified biochar catalysts in enhancing MAHs production from microalgae, providing a promising strategy for aromatic generation.
✓ 已验证
产品关联
DOI
高影响因子
MICROCHEMICAL JOURNAL
·
2025
·
IF 5.1
Xinmei Qian,Chunxiang Li,Mingyu Zheng,Keqin Deng
A flower-like S, N-codoped carbon nanosheets loaded with hybrid magnetic nanoparticles (HMNPs/S,N-CNSs) by using MOF as precursor was prepared. The morphology, composition, microstructure, and property were evaluated by SEM, HRTEM, EDS, XRD, XPS, magnetic analysis, and cyclic voltammetry. The hybrid nanoparticles were composed of most Fe 3 O 4 , some CoFe alloy, and a few Fe 2 S. The magnetic material showed high magnetism and brilliant electrocatalysis towards the electrochemical reduction of antibiotic nitrofurazone (NFZ). By utilizing screen-printed electrode (SPE) and HMNPs/S,N-CNSs, a disposable electrochemical NFZ sensor (HMNPs/S,N-CNSs/SPE) was fabricated by magnetic control. The current signal of NFZ at HMNPs/S,N-CNSs was 6.38 times higher than that of bare SPE. It displayed a wide detection range of 0.01–50 μM with a detection limit of 4.2 nM (S/N = 3). The practical applicability of the sensor in real samples presented satisfactory results. The disposability, low cost, high sensitivity, low consumption volume in analyses, and good selectivity make the proposed sensor a promising tool for NFZ detection.
✓ 已验证
产品关联
DOI
高影响因子
ELECTROCHIMICA ACTA
·
2026
·
IF 5.8
Qiao Wan,Yajun Li,Yahong Su,Wenqing Jia,Jiang Zhu,Qiang Yu,Zhen Chen,Lingli Lei,Yuanyuan Zhang
This study aims to develop a high-performance, low-cost non-enzymatic electrochemical sensing materials for glucose detection, addressing the limitations of existing technologies. A three-dimensional porous hierarchical layered-nanoflower heterostructured CuCoP/MXene composite was synthesized through in situ growth of CuCo-MOF nanoflowers on Ti 3 C 2 -MXene via a one-step hydrothermal method, followed by oxidation and phosphidation treatments. This unique architecture significantly increases the specific reactive surface area, exposes abundant active sites, and provides sufficient interfacial regions for glucose oxidation. The synergistic effect between copper (Cu) and cobalt (Co) further enhances the electrocatalytic performance. Meanwhile, MXene serves as a conductive scaffold that not only facilitates electron transfer but also promotes the diffusion and adsorption of glucose molecules, owing to its excellent conductivity and continuous interlayer channels. The fabricated sensor exhibits an extensive linear detection range (0.5-6000 μM), high sensitivity (1408.49 μA mM -1 ·cm -2 ), a low detection limit (0.14 μM, S/N=3), along with excellent selectivity, reproducibility, and stability, together with a swift response time (3 s). Moreover, the sensor has been successfully applied to the accurate detection of glucosein samples of serum, showing high reliability and promising practical value.
✓ 已验证
产品关联
DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2026
·
IF 12.5
Zhen Zhang,Xiaojian Tian,Yuxiao Sun,Dandan Han,Bang Gu,Dan Wu,Armin Rezayan,Xian Wu,Jingpeng Zhao,Jianshe Wang,Tianliang Lu,Renfeng Nie,Xiaoqin Si,Chunbao Xu,Yongsheng Zhang
Vanadium-based catalysts are widely used in the oxidation of carbohydrates to produce formic acid (FA), a promising liquid organic hydrogen carrier, but still suffers from low yield due to the formation of CO 2 . This study found that the spatially isolated VO x on active carbon (AC) can significantly increase FA yield from 43.5 to 72.9% in glucose oxidation compared with free VO x . Two specific roles of AC were revealed. Firstly, the oxygenated functional groups, high surface area and abundant microporous of AC, play a crucial role in the atomic dispersion of VO x , resulting in a heterogeneous, single-site VO x -AC catalyst. The isolated VO x site favors the oxidative C C bond cleavage in glucose via a stepwise α-cleavage pathway, thus improving FA selectivity. Secondly, the conductive AC acts as an electron buffer, which accelerates the catalytic redox cycle between V 5+ and V 4+ of the isolated VO x sites, thus increasing the reaction activity. The prepared single-site VO x -AC catalyst is reusable and can generate a concentrated FA solution (4.7 wt%) by simple filtration of the solid catalyst. This work presents a simple method for the production of H 2 energy carrier from biomass and provides a fundamental basis for designing efficient catalytic systems for aqueous-phase oxidation reactions.
✓ 已验证
产品关联
DOI
高影响因子
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
·
2026
·
IF 3.8
Li Anan,Lu Shijie,Shang Xueqing,Zhang He,Xie Min,Lu Qiao,Hu Yongjun
Mass spectrometry imaging (MSI) enables spatial mapping of chemical distributions across complex surfaces, with broad applications spanning materials analysis, life sciences, and clinical diagnostics. However, conventional ionization sources often suffer from limited ionization efficiency, creating a trade-off between detection sensitivity and spatial resolution. Post-ionization technology addresses this constraint by incorporating a secondary ionization step, significantly enhancing ionization yield and establishing itself as a leading approach for advancing mass spectrometry techniques. In this study, we have independently developed a vacuum ultraviolet-laser desorption post-ionization mass spectrometry (VUV-LDPI-MS) system, which significantly enhances detection sensitivity through the implementation of post-ionization technology. By integrating low-photon-energy long-wavelength laser desorption with the soft-ionizing capability of VUV light, this technique enhances the detection of chemical species within biological tissues—including both exogenous drugs and endogenous metabolites. The method achieved a theoretical detection limit of 8.3 pg/spot for methylene blue (MB), while markedly reducing substrate effects and sample background interference. Imaging results revealed that endogenous compounds closely aligned with zebrafish tissue anatomy, whereas the spatial distribution of exogenous MB strongly correlated with optical images. Successful application to zebrafish tissue sections enabled clear visualization of both MB and intrinsic metabolites. VUV-LDPI-MSI offers superior ionization efficiency with minimal sample preparation, presenting a robust alternative to conventional LDI-MS approaches and holding considerable promise for future technological development.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Journal of Materials Chemistry A
·
2026
·
IF 9.5
Guangmeng Chen,Ziqiang Hu,Yuan Liu,Li Jia,Weiwei Zhao,Xiaoqing Liu
Non-enzymatic electrochemical glucose sensors (NEGS) offer advantages over enzymatic counterparts, but conventional supporting scaffolds suffer from poor conductivity, limited surface area, and binder dependence. Herein, we present a strategy to fabricate high-performance, binder-free NEGS based on a hierarchical laser-induced graphene/carbon fiber framework (LW-CFF-B) functionalized with NiO nanoparticles. The 3D porous LW-CFF scaffold is engineered by in-situ carbon fiber felt (CFF) enhanced LIG using 1,4-phenylenediboronic acid (PA) modified liquid benzoxazine (PGE-a) as the precursor. PA serves a dual role in enhancing carbon yield and improving electrical conductivity (sheet resistance reduced from 2.54 to 1.23 Ω/sq). Moreover, PA promotes the formation of a hierarchical porous carbon architecture, which is beneficial for facilitating electrochemical performances of the obtained carbon product. Subsequent laser assisted deposition of NiO nano-layer on LW-CFF-B scaffold yields the LW-CFF-B-Ni electrode. This optimized architecture combines mechanical integrity with exceptional electrocatalytic properties, leading to outstanding glucose sensing performance: ultrafast response (1.2 s), ultrahigh sensitivity (5758 μA mM⁻¹ cm⁻²), a low detection limit (0.16 μM), and excellent selectivity against common interferents. The developed sensor demonstrates appreciable recoveries (91.1% to 107.3%) regarding glucose concentration in beverages. These outstanding analytical results demonstrate significant potential for this sensor in precise glucose monitoring.
✓ 已验证
产品关联
DOI
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2026
·
IF 8.5
Weimin Xing,Wenyan Liu,Bei Yang,Linwang Fan,Yan Zhou,Zhuoyue Wang,Cheng Niu,Jiacheng Li,Yuhong Feng
To mitigate environmental pollution and food contact safety concerns associated with traditional non-biodegradable plastic packaging, biodegradable and edible polysaccharide-based materials such as bacterial cellulose (BC) can serve as an ideal alternative for food packaging. In this paper, BC/Nisin/SA-PBA composite films were prepared using an in situ multi-crosslinking strategy to enhance the mechanical strength, barrier performance, and antimicrobial activity of BC films. The goal was to develop biodegradable and food-contact safe packaging films based on BC composites. Specifically, amphiphilic alginate derivatives (SA-PBA) were synthesized and incorporated during the bacterial cellulose biosynthesis together with Nisin, while subsequent cross-linking with Ca 2+ was performed after harvest. Compared to pure BC film, the BC/Nisin/SA-PBA composite film containing 0.2 wt% SA-PBA exhibited significant improvements in mechanical properties, with tensile strength (TS) increasing by 3.08 times (24.77 MPa) and elongation at break (EAB) increasing by 37.51 times (16.13%). The oxygen transmission rate (OTR) and water vapor permeability (WVP) decreased by 98.11% and 80.93%, respectively. Additionally, the composite film demonstrated excellent antimicrobial activity, particularly against Staphylococcus aureus , and extended the shelf life of pork to 10 days at 4 °C. The film significantly reduced the total volatile basic nitrogen (TVB-N) and total viable count (TVC), indicating its potential for preserving food quality. This work proposes a novel in situ multi-crosslinking strategy to develop biodegradable, food-safe, and high-performance food packaging materials.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Cells
·
2026
·Vol. 15
·期 2
·208
·
IF 5.2
Xianjun Wang,Weibing Zhang,Hong Hu,Wenjing Gao,Xu Ma,Yarong Wu,Yongfeng Qiao,Yang Wang,Ding Zhang,Chunbo Dong,Haidong Wang,Zhida Liu
Highlights What are the main findings? A highly efficient veterinary vaccine platform was developed using cellular membrane nanovesicles (CMN) and validated for PEDV by presenting the spike protein. The CMN-based PEDV vaccine elicited robust humoral and CD8 + T cell immune responses in both murine and porcine models, accompanied by notable virus-neutralizing antibody production. What are the implications of the main findings? The CMN-based platform enables multivalent PEDV vaccine design by co-expressing spike proteins from diverse viral variants to elicit broad-spectrum protection. The CMN-based approach provides a versatile strategy for the modular development of polyvalent and multivalent veterinary vaccines via co-expression of antigens from distinct virus. Porcine epidemic diarrhea virus ( PEDV ) has emerged as a major pathogen responsible for porcine diarrheal diseases, causing outbreaks of severe diarrhea and high mortality in neonatal piglets, thereby inflicting severe economic losses on the global swine industry. Current commercial PED vaccines, comprising conventional inactivated and live attenuated formulations, have exhibited progressively diminished efficacy in the face of emerging PEDV variants. The development of high-efficiency vaccine platforms is therefore critical for PED control. This study engineered a cellular membrane nanovesicle (CMN)-based vaccine, which differs from existing inactivated or subunit vaccines by presenting the PEDV spike (S) protein on the cell membranes to mimic the bilayer phospholipid structure of the viral envelope. The full-length S protein (FS, aa 19-1309) or a truncated S protein fragment (TS, aa 19-726) was expressed in Expi293F cells, followed by extraction of cell membranes to assemble antigen-displaying CMN vaccines. Compared with commercial live attenuated vaccine, administration of the CMN vaccine elicited high-titer neutralizing antibodies and elevated IFN-γ-producing CD8 + T cells in murine studies. Safety assessments revealed no adverse effects on body weight, hepatic/renal function indices, or histopathological parameters in vaccinated mice. Furthermore, immunization of piglets elicited notable humoral and CD8 + T cell immune responses. Collectively, the strategy of CMN-based vaccine described herein delivers a potential PEDV vaccine platform, thereby offering a novel avenue for next-generation veterinary vaccine development.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Food Bioscience
·
2026
·
IF 5.9
Shijin Huang,Ganggang Zhang,Zongyou Chen,Jiawei Chen,Xiaocui Lai,Weihua Lai
Chlortetracycline (CTC), a broad-spectrum veterinary antibiotic, poses serious risks to human health through bioaccumulation due to excessive use. To address the critical need for CTC monitoring, we developed a fluorescence quenching lateral flow immunoassay (FQ-LFIA) employing black bimetallic hollow nanoparticles (BBHNPs) as quencher. BBHNPs were engineered with a unique dual-advantage architecture: an internal hollow structure for enhanced light capture capability and an external polydopamine layer for higher spectral overlap with fluorophores. This design resulted in exceptional photophysical characteristics, including a remarkable molar extinction coefficient (2.18×10 12 L mol -1 cm -1 ) and an unprecedented fluorescence quenching constant (5.20×10 13 L mol -1 ). BBHNP-based FQ-LFIA achieved a limit of detection (LOD) of 0.32 ng mL -1 , representing a 6.91-fold improvement over conventional gold nanoparticle-based lateral flow immunoassay (LFIA). Validation studies in spiked milk samples showed excellent recovery rates (87.73-118.09%) with high precision (coefficient of variation < 10.36%). Method comparison with liquid chromatography-tandem mass spectrometry (LC-MS/MS) analysis confirmed the reliability of BBHNP-FQ-LFIA for real-world applications.
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）