DENTAL MATERIALS
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2025
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IF 6.3
Jiajia Xu,Yanji Lu,Kai Zhang,Qiaojie Luo,Xiaodong Li
Objective To compare the bonding efficacy of one-step versus two-step calcium fluoride (CaF₂) nanoparticle deposition and to elucidate the underlying mechanisms. The null hypotheses tested are as follows: 1) Nanoparticles deposited via the one-step strategy are less uniformly distributed than those deposited via the two-step strategy; 2) The one-step strategy does not release more confined water compared to the two-step strategy; 3) The one-step strategy is inferior to the two-step strategy in enhancing dentin bonding durability. Methods A stable amorphous calcium fluoride (ACF) precursor solution was prepared by mixing 10 mM CaCl₂ and 10 mM NaF in 20 mM HEPES buffer for 20 s, enabling one-step CaF₂ nanoparticle deposition through the mineralization-regulating function of non-collagenous proteins acting as pseudonuclei. The two-step strategy consisted of sequentially applying 0.1 M CaCl₂ and 0.2 M NaF, each for 20 s. Neutralization of matrix negative charges, reduced hydration capacity, and confined water release were assessed via cationic dye adsorption, zeta potential, water contact angle, ATR-FTIR spectroscopy, and thermogravimetric analysis. Interface characteristics were evaluated using SEM, TEM, and XPS. Bonding effectiveness was determined by adhesive infiltration depth, micro-tensile bonding strength (μTBS), and nanoleakage expression, both initially and after aging. Results Our results demonstrate that the one-step strategy produces smaller, more homogeneous nanoparticles that penetrate collagen fibrils more effectively. We thus reject the null hypothesis 1. Compared to the unmodified demineralized dentin matrix (DDM), the DDM obtained with the two-step approach exhibits reduced interfacial water, which further reduced by the one-step strategy. The null hypothesis 2 is thus rejected. Compared to the conventional wet-bonding control (AW), bonding performed on these optimized DDM leads to enhanced adhesive infiltration. Both one-step (ACF) and two-step strategies (CW) improve the immediate bonding strength (43.00 ± 4.15 MPa and 36.81 ± 3.32 vs. 31.57 ± 2.02 MPa). after 12 months of storage in water at 37 °C, bonding strength of the AW group significantly decreased to 26.92 ± 2.35 MPa (p < 0.05), whereas the CW group decreased to 30.20 ± 4.66 MPa (p < 0.05) and the ACF group maintained a high level (39.22 ± 5.12 MPa, p > 0.05). Significance This novel one-step dentin bonding strategy effectively addresses the challenge of dentin bonding durability. By simultaneously reduced electronegativity, lower hydration capacity, decreased confined water, enhanced mechanical properties, and reinforcement at the basal level, adhesive infiltration was improved, clinical procedure was simplified, and bond durability was sustained provided. The one-step dentin bonding strategy offers a clinically practical, time-efficient, and superior alternative for durable resin-dentin bonds.
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DOI
PubMed
高影响因子
CERAMICS INTERNATIONAL
·
2025
·
IF 5.6
Wentao Guo,Xi Lan,Yongli Jin,Ziqi Ding,Jintao Gao,Zhancheng Guo,Zengwu Zhao
The irreplaceability role of rare earths in high-performance materials, such as ceramics, highlighting the significance of rare earth extraction. Strengthening the crystallization growth of the rare earth phase in rare earth slag is crucial for ensuring effective subsequent rare earth enrichment and separation. However, viscosity plays a major role in the characteristics of high-temperature melts and the crystallization process. In this study, an internal column rotation method was used to measure the viscosity of CaO-SiO 2 -CaF 2 -Ce 2 O 3 slag melts. The effect of shear rate on the rheological behavior of CaO-SiO 2 -CaF 2 -Ce 2 O 3 slag with varying Ce 2 O 3 and CaF 2 contents, and CaO/SiO 2 ratio was investigated by examining the viscosity evolution during the rare earth crystallization growth process. The rheological behavior of the CaO-SiO 2 -CaF 2 -Ce 2 O 3 slag was elucidated in regions of liquid phase, low solid phase, and high solid phase, providing insight into the viscosity changes of non-Newtonian flowing melts. Based on this, the effect of shear rate on the crystallization behavior of rare earth phases was investigated to provide a basis for improving the subsequent separation of rare earth phases.
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高影响因子
ACS Nano
·
2021
·
IF 15.881
Zhao Jiang,Liangrui He,Xujiang Yu,Zhiwen Yang,Weijie Wu,Xiaoyan Wang,Rihua Mao,Daxiang Cui,Xiaoyuan Chen,Wanwan Li
X-ray-induced photodynamic therapy (XPDT) is overwhelmingly superior in treating deep-seated cancers. However, limitations remain, owing to a combination of the poor scintillation performance of the nanoscintillator, low energy transfer efficiency of the therapeutic nanoplatform, and hypoxic environment presented in the tumor tissue. Collectively, these reduce the curative effect of XPDT. Here, we report a highly efficient, low-dose XPDT realized by systematic optimization from scintillation efficiency, nanoplatform structure, to therapeutic approach. We developed a biocompatible, codoped CaF2 nanoscintillator that emitted sufficiently green radioluminescence that was bright enough to be seen by the naked eye. Using dendrimers as a framework, we built a nanoplatform featuring a dual-core–satellite architecture, which enabled both procedurally and spatially separate dual-loading of therapeutic agents. This strategy allowed for the fabrication of a combined XPDT and antiangiogenic therapy, resulting in a therapeutic system capable of simultaneous tumor attacks. After exposure to ultralow dose radiation, XPDT resulted in marked tumor reduction while the antiangiogenic drug effectively blocked tumor vascularization exacerbated by XPDT-mediated hypoxia, rendering a pronounced synergy effect. This system also showed high biosafety, as the agents adopted had been used clinically and both Ca and F elements were widespread in the human body. Taken together, the findings presented here provided a reference for the construction of complex, multiloading architecture in coordination with structural complexity and functional diversification. This work provided a safer and more robust application of the combined XPDT and antiangiogenesis in future clinical treatment settings.
研究领域:
癌症研究
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放射肿瘤学
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纳米技术
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生物医学工程
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治疗策略
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DOI
PubMed
高影响因子
Environmental Science-Nano
·
2025
·
IF 5.1
Guangxin Liao,Li Li,Zeyu Kang,Xibing Zhou,Jie Li,Zhulin Xue,Huiqin Gao,Zhang Lin,Weizhen Liu
Fluorine-containing sludge (FCS), an industrial hazardous waste generated during processes such as fluorine chemical production and solar cell manufacturing, is highly toxic and challenging to degrade, posing significant environmental threats. In this study, we developed a promising new method to convert FCS into monodisperse, highly crystalline, and high-purity CaF2 nanomaterials using low-concentration inorganic or organic acids as regulators under hydrothermal conditions. This method involved regulating the dissolution–deposition behaviours of the CaF2 matrix, controlling impurity transformation, promoting the growth of CaF2 crystals and achieving deep removal of impurities. Under optimized conditions (0.5 M hydrofluoric acid, liquid-to-solid ratio of 10 : 1, 180 °C, and 24 h), the produced CaF2 exhibited 98% purity, 99% crystallinity and excellent monodispersity. The purification and impurity separation mechanism of CaF2 in FCS was studied by analysing the dissolution–deposition process, the crystal growth behavior of CaF2, and the migration and transformation of impurities under the treatment. It was revealed that hydrofluoric acid, as a regulator, plays the following important roles: (i) targeted conversion of calcium in sludge into CaF2 and enhancement of its purity, (ii) regulation of the digestive ripening process of fine CaF2 particles and enhancement of the dispersity and crystallinity of the CaF2 product, and (iii) release of encapsulated and lattice-doped impurities and dissolution of other solid impurities into the liquid phase. Ultimately, this process yielded monodisperse, high-crystallinity, acid-grade CaF2 nanomaterials. This study provided critical insights into the nano-structure control and transformation of hazardous FCS, thereby developing a sustainable approach to fluorine resource recovery.
研究领域:
环境科学
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材料科学
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化学工程
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DOI
高影响因子
SURFACE & COATINGS TECHNOLOGY
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2025
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IF 6.1
Zhihui Zhang,Jianxin Deng,Shiyao Rong,Junyan Wang,Yichen Bao
To further enhance the lubrication performance of composite coatings, this study employed an electrospray masking in-situ forming technology to fabricate textured (CF x ) n /CaF 2 /C-ZrO 2 /TiO 2 composite coatings. Their microstructures, mechanical properties, and reciprocating wear behaviors were investigated. Results showed that this technique could directly create high-quality chessboard microtextures during coating fabrication, integrating multiple materials on a single surface. Compared to non-textured LT samples, the CBM samples demonstrated enhanced coating-substrate adhesion strength (132 N, increased by 11 %), low friction coefficient (~0.09, reduced by 18.2 %) and wear rate (~1.86 × 10 −7 mm 3 ·N −1 ·mm −1 , reduced by 42.4 %) at 25 °C, and excellent self-lubricating performance across 200–600 °C. Mechanism analysis revealed that the chessboard structure exhibited a synergistic effect with the coating materials.
研究领域:
材料科学
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表面工程
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DOI
高影响因子
MATERIALS CHEMISTRY AND PHYSICS
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2024
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IF 4.3
Shuo Tian,Hao Yang Shen,Jun Jie Huang,Hao Zhang,Kai Ge Liu,Bin He,Jianwei Zhao,Ling Bing Kong
When preparing glass-ceramics using sintering method, porosity is the main reason affecting their properties. To achieve glass-ceramics with low thermal expansion performance, cold isostatic pressing is adopted to significantly reduce the porosity. In this study, we systematically analyzed the effect of CaF 2 /CaO content on sintering behavior, microstructure and properties of Li 2 O–Al 2 O 3 –SiO 2 (LAS) glass-ceramics. It was found that the [CaF 2 ]/([CaO]+[CaF 2 ]) ratio x can be used to regulate the coefficient of thermal expansion (CTE) of the LAS glass-ceramics. The optimized sample has a CTE of 2.2865 ppm/°C, which is compatible with that of silicon (2.5 ppm/°C). At the same time, low dielectric constant (5.95 ≤ ε r ≤ 8.89) and dielectric loss (1.179 × 10 −3 ≤ tanδ ≤2.871 × 10 −2 ) were observed, which makes them a promising candidate for low-temperature co-fired ceramic substrate applications.
研究领域:
材料科学
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陶瓷工程
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电气工程
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DOI
高影响因子
ACS Applied Nano Materials
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2022
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IF 6.14
Wubin Lv,Jin Ye,Qiang Wang,Chunsheng Li,Jun Wang,Zhiyong Zhang,Na Niu,Zhiguo Liu,Jiating Xu,Yujie Fu
Rare earth (RE)-based inorganic upconversion nanoparticles (UCNPs) have huge potency for applications varying from bioimaging to theranostics of tumors. For these applications, it is of great importance that UCNPs be expelled innocuously from a living body during a rational period of time after executing their diagnostic and/or therapeutic tasks. Despite great efforts to modulate biodegradability, a reasonable biodegradation rate for currently available UCNPs in weakly alkaline physiochemical buffers has not yet been realized. Herein, to achieve a tunable biodegradation rate for UCNPs, a class of core–shell-structured nanoparticles is invented by heteroepitaxially growing a CaF2:Yb shell with varying Zr4+ doping content on a biodegradable Na3ZrF7:Yb,Er core. The CaF2:Yb,Zr shell can not only enhance the emission intensity but also ensure the overall biodegradation of the nanocrystals. The degradation rate of core–shell UCNPs can be easily modulated by changing the Zr4+ doping content in the shell, and the degradation rate is pH-responsive; thus, tumor acidity-triggered degradation can be realized. When sodium alginate (SA)-modified UCNPs are used for the bioimaging of tumors, the intracellularly degraded metal ions and the released SA molecules can self-assemble through a coordination cross-linking effect, thereby improving the tumor retention of the nanosystems. These discoveries will unequivocally promote the future clinical applications of RE-based UCNPs.
研究领域:
纳米技术
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生物医学工程
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材料科学
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癌症研究
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光学成像
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DOI
高影响因子
Journal of Materials Research and Technology-JMR&T
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2025
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IF 6.6
Zhihui Zhang,Jianxin Deng,Lingxuan Fan,Junyan Wang
The paper presents the fabrication of chessboard-structured (CF x ) n /CaF 2 /C–ZrO 2 /TiO 2 lubricant-hard alternate coatings by electrospray mask in-situ forming technique. The influence of the coating's structure and components on microstructure, film-substrate adhesion strength, and reciprocating wear performance were studied. The results showed that the chessboard structure of the hard coating had a high surface energy of 83.45 mJ/m 2 , which enhanced the adhesion of the lubricant coating. The addition of graphite (C) improved the uniformity, thermal stability, and lubrication of the (CF x ) n /CaF 2 lubricant coating. Within the 25–600 °C temperature range, the chessboard-textured (CF x ) n /CaF 2 /C–ZrO 2 /TiO 2 lubricant-hard alternate coating all exhibited low friction coefficients, which attributed to the synergistic effect between chessboard structure and coating material.
研究领域:
材料科学
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表面工程
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DOI
高影响因子
JOURNAL OF PHYSICS AND CHEMISTRY OF SOLIDS
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2021
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IF 3.995
Zhiyu Liu,Jianhe Tang,Congcong Piao,Xing Zhang,Xiaochen Qi,Ying Tian,Dawei Fang,Jun Wang
A novel Z-scheme CaF 2 :Yb 3+ ,Er 3+ @ZnTiO 3 /Au/CdS photocatalyst has been prepared. In this system, an excellent up-conversion luminescent agent, CaF 2 :Yb 3+ ,Er 3+ , is introduced to broaden the light response range. The Au surface plasmon resonance effect endows the system with highly efficient charge transfer. The photocatalytic activity of the Z-scheme CaF 2 :Yb 3+ ,Er 3+ @ZnTiO 3 /Au/CdS photocatalyst has been evaluated in the degradation of norfloxacin (NOR) with simultaneous hydrogen production . Some influencing factors, such as solar light irradiation time, sacrificial agent concentration, and number of reuse cycles, are discussed. The emission spectrum and energy conversion mechanism of CaF 2 :Yb 3+ ,Er 3+ have also been studied. The prepared photocatalyst facilitated a significant degree of degradation (92.05%) of NOR and considerable hydrogen production (513.39 μmol/g) under solar light irradiation for 5.0 h. Moreover, it showed high stability in photocatalytic NOR degradation with simultaneous hydrogen production over five cycles. A possible mechanism for photocatalytic degradation of NOR with simultaneous hydrogen production promoted by the Z-scheme CaF 2 :Yb 3+ ,Er 3+ @ZnTiO 3 /Au/CdS photocatalyst is proposed.
研究领域:
环境科学
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材料科学
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DOI
高影响因子
CERAMICS INTERNATIONAL
·
2021
·
IF 4.527
He Sun,Yusheng Yang
Neodynium oxyfluoride has been applied for luminescence materials and solid electrolytes because of its structure combined advantages of rare-earth cations with F − and O 2− anions. Since the neodynium oxyfluoride with tetragonal structure retains a defect structure having anion vacancies where anions transfer, it shows higher anion conductivity than that with cubic and rhombohedral structures. The feasibility of synthesizing tetragonal neodynium oxyfluoride in molten fluorides was investigated in this work. The neodynium oxyfluoride was not dissolved in molten LiF–CaF 2 based on the in-situ observation using confocal scanning laser microscope, therefore neodynium oxyfluoride can be easily collected from molten fluorides. The neodynium oxyfluoride with tetragonal structure was successfully synthesized by the reaction of Nd 2 O 3 with molten fluorides. The synthesis process was analyzed by differential scanning calorimetry combining X-ray diffraction and scanning electron microscope. The reaction model was described and the reaction rate constant was calculated. According to the mathematical description of kinetic equation, the reaction rate could be proportional to the interface difference between molten fluorides and solid Nd 2 O 3 .
研究领域:
材料科学
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固体化学
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电化学
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DOI
高影响因子
Journal of Materials Chemistry A
·
2023
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IF 11.9
Yingdan Song,Jianqiang Xiao,Lei Zhao,Zhichao Liu,Yami Ling,Yingjuan Yan,Yixuan Xu,Alexey Nikolaevich Yakovlev,Tingting Hu,Tatiana Grigorievna Cherkasova,Qiang Xu,Canjun Wang,Xuhui Xu
The smart mechanical sensing technology based on mechanoluminescence (ML) has potential applications in the fields of wearable mechanical sensors and remote detection of human health due to its characteristics of non-contact, visualization, and remote signal transmission. Herein, a new strategy for multi-mode ML in the rigid and flexible medium by embedding fluoride nanocrystals (CaF2: Tb3+) in amorphous media was proposed and the intrinsic physical mechanism of energy conversion was clarified. For the rigid transparent CaF2: Tb3+ glass ceramics (GCs), without being fabricated with any special medium, recoverable trap-controlled ML can be generated under friction after X-Ray pre-irradiation. Furthermore, the ML composite device fabricated using CaF2: Tb3+ GCs powder and flexible stretchable polydimethylsiloxane (PDMS) can achieve self-recovery ML under multimode mechanical stimulation due to the induction of inorganic-organic interface triboelectrification. Finally, a rigid accurate stress detection at non-stressed point positions is designed based on the remote transmission of ML signal owing to the unique optical waveguide effect of GCs, and a flexible mechanical-sensing optical skin for real-time monitoring of human health status is realized by CaF2: Tb3+ GCs powder/PDMS composite device. This work opens up a new avenue for the realization of multi-scene stress detection based on rigid/flexible ML material.
研究领域:
材料科学
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光学
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机械工程
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生物医学工程
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传感器与执行器
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DOI
高影响因子
危险品化学品经营许可证（带存储）