JOURNAL OF SOLID STATE CHEMISTRY
·
2025
·
IF 3.5
Jun Liu,Yongpeng Chen,Xiuyan Zhang,Zhenye Ma
In this article, copper-based metal organic framework (MOF) HKUST-1 was synthesized via room temperature stirring method, and a series of HKUST-1/AP composite particles with different mass ratios were prepared via mechanical grinding method; The morphology and structure of the prepared HKUST-1 were characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM), Transmission electron microscopy (TEM), fourier transform infrared spectroscopy (FTIR), and X-ray photoelectron spectroscopy (XPS), and the particle size data were measured by laser particle size analyzer; Thermogravimetric analysis-differential scanning calorimetry (TG-DSC) was employed to evaluate the catalytic activity of HKUST-1 during AP thermal decomposition. The results revealed that variations in copper salt type exerted a marked influence on HKUST-1's powder particle size. The addition of 4 % HKUST-1-C, HKUST-1-S, HKUST-1-N, and HKUST-1-Cl respectively reduces the high-temperature decomposition (HTD) temperature of AP by 113.5 °C, 113.1 °C, 107.4 °C, and 107.7 °C. Concurrently, the heat release of AP undergoes a dramatic increase, rising from the initial 415.71 J/g to 1188 J/g, 1181 J/g, 864.8 J/g, and 856.8 J/g for each corresponding sample. Among them, HKUST-1-C demonstrated superior catalytic performance, characterized by a remarkable reduction in the HTD of ammonium perchlorate by 110.8 °C with only a 2 % addition. Notably, this catalyst enhanced heat release by 750.3 J/g and decreased the reaction activation energy by 66.9 kJ/mol, thereby significantly improving the overall thermodynamic efficiency of the system.
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NANO
·
2025
·
IF 1.1
Peixuan Zou,Yusong Pan,Kuen-Song Lin,Wei-Chin Tsai,Yinghai Xie,Wenjie Luo,Run Huang,Xiuling Lin
The use of nanocarriers with combined photothermal and chemotherapeutic methods has been widely accepted as a promising anti-tumor treatment strategy. Leveraging the tumor-specific microenvironment, these nanocarriers enhance therapeutic outcomes. Our research developed an innovative drug carrier platform, which was composed of the Metal-Organic Framework (MOF) HKUST-1 as a drug carrier and the Fe 3 O 4 nanoparticles as a photothermal functional phase. This novel carrier demonstrated an impressive drug loading rate of 110% for Doxorubicin (DOX), suggesting a high capacity for drug delivery. Additionally, the as-prepared nanocarrier also displayed excellent photothermal conversion capability, which can efficiently convert light into heat under near-infrared light with 980 nm irradiation, thus utilizing photothermal therapy for tumors. The release mechanism of pH sensitivity of the carrier expedited drug release under acidic conditions, aligning with the tumor microenvironment. Biocompatibility assays confirmed the excellent compatibility of Fe 3 O 4 @HKUST-1 with normal tissue cells. While photothermal therapy alone successfully induced apoptosis in tumor cells, the treatment’s efficacy requires improvement as cell viability remained at 80%. Conversely, combining chemotherapy with photothermal therapy decreased cell viability to 30%, thereby effectively inhibiting proliferation. In sum, the Fe 3 O 4 @HKUST-1 drug delivery system exhibits significant potential in medical applications due to its dual-therapy approach.
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SEPARATION AND PURIFICATION TECHNOLOGY
·
2022
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IF 9.136
Fei Yu,Xueting Bai,Mingxing Liang,Jie Ma
Considering the increasingly serious levels of antibiotic pollution, it is necessary to find new and efficient adsorbents. In this study, the adsorptive removal of a model quinolone antibiotic, ciprofloxacin (CIP), from wastewater is presented using a metal–organic framework (MOF)-derived carbon. HKUST-1-derived carbon (HDC-1100) was obtained by high-temperature carbonization of the HKUST-1 precursor at 1100 °C. HDC-1100 has a regular octahedron shape decorated with Cu/Cu 2 O particles and has a microporous and mesoporous structure with abundant oxygen-containing functional groups on the surface. Within 48 h, HDC-1100 could reach adsorption equilibrium for 30 mg·L -1 CIP, and the kinetic data were fitted with a pseudo-first-order model and a pseudo-second-order model. In this study, the maximum adsorption capacity of HDC-1100 for CIP was as high as 592 mg·g −1 . The high adsorption capacity is attributed mainly to metal–organic complexation, electrostatic interactions, and hydrogen bonding. Also, the effects of environmental factors, such as pH, ionic strength, and humic acid, on the adsorption capacity were considered. This study is significant for the treatment of high-concentration antibiotic-polluted wastewater.
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APPLIED ORGANOMETALLIC CHEMISTRY
·
2022
·Vol. 36
·期 6
·e6693
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IF 4.072
Jiale Liu,Mengyao Huang,Zhongyu Hua,Jiatong Ni,Yi Dong,Zeran Feng,Tiedong Sun,Chunxia Chen
Chemodynamic therapy (CDT) uses the conversion of H 2 O 2 to ·OH triggered by Fenton-like reactions to treat tumors, but the treatment is not complete due to insufficient intracellular H 2 O 2 content. Photothermal therapy (PTT) uses photothermal materials for photothermal conversion to kill tumors, but it is limited by the extent of exogenous light transmission and cannot achieve satisfactory therapeutic effects. Therefore, designing a composite nanomaterial that amplifies CDT and couples it with PTT for tumor treatment is a major challenge. Herein, we designed a W-POM NCs@HKUST-1 nanoplatform that combines PTT and CDT and has better targeting properties. It shows high stability and photothermal conversion efficiency under the irradiation of near-infrared light and efficiently catalyzes the generation of intracellular hydroxyl radicals, this composite material exhibits higher lethality than single therapeutic strategies. This study expands the application area of POM@MOF composite nanomaterials and provides a promising means of enhanced tumor therapy.
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JOURNAL OF HAZARDOUS MATERIALS
·
2021
·
IF 10.588
Xiaoyan Ma,Lei Wang,Hong Wang,Jing Deng,Yali Song,Qingsong Li,Xueyan Li,Andrea M. Dietrich
Natural organic matter (NOM) has rich halogenation reactive sites, therefore acts as the main precursor of disinfection byproducts (DBPs) in the chlorine disinfection process during drinking water treatment . In this research, high-quality metal-organic framework HKUST-1 is rapidly synthesized by a solvothermal method, and we are the first to report adsorption of aqueous humic acid (HA), representing NOM, and its adsorption behavior, influencing factors, and recycling capability. The crystalline HKUST-1 possessed a microporous framework with a high 1385 m 2 /g specific surface area, and three-dimensional structure as characterized by Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), scanning electron microscope (SEM). 99% removal of 5 mg/L HA was observed at pH 5.8, room temperature, and 0.6 g/L HKUST-1. The maximum capacity was 14.42 mg HA/g HKUST-1 at room temperature. The Langmuir adsorption isotherm , quasi-second-order kinetic model, and thermodynamic parameters accurately describe the spontaneous and disorderly endothermic adsorption of HA by HKUST-1. The desorption regeneration process was accomplished by washing HKUST-1 with NaOH and calcination ; it showed that HKUST-1 was viable in three regeneration cycles. The mechanism of HA adsorption by HKUST-1 is electrostatic and synergistic interaction between π-π bonding, and hydrogen bonding. HKUST-1 is a potential treatment strategy to remove NOM.
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ENVIRONMENTAL TECHNOLOGY
·
2021
·
IF 3.247
Min Xiaobo,Li Xinyu,Zhao Jie,Hu Xiaoxian,Yang Weichun
Aiming at exploring an effective photocatalytic adsorbent for organic dye removal, a series of heterostructured TiO2@HKUST-1 photocatalysts, by incorporating HKUST-1 with different TiO2 nanoparticles loading, were prepared by single-step hydrothermal method. The morphology and surface characteristics of the as-prepared TiO2@HKUST-1were analyzed using SEM, HRTEM, XRD, FTIR, UV–vis DRS, and Photoluminescence techniques. The adsorption-photocatalytic degradation of the model dye methylene blue (MB) on the catalysts was investigated. It was indicated that the introduction of a certain amount of TiO2 on the surface of HKUST-1 could improve the transfer and separation of the photogenerated charge carriers, resulting in the enhanced photocatalytic activity. The optimal 0.02TiO2@HKUST-1 exhibited the highest MB removal rate with about 4.4 and 19.3 times as high MB removal efficiency as that of HKUST-1 and TiO2, respectively. Heterostructured TiO2@HKUST-1 materials for the removal of MB involved the integrated adsorption and visible light photocatalysis. Meanwhile, the composite exhibited good reusability in the process of cyclic experiments. Therefore, this work provides a potential MOF-based photocatalytic adsorbent for organic dye removal.
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BIOSENSORS & BIOELECTRONICS
·
2016
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IF 7.476
Shuisheng Hu,Wenjun Ouyang,Longhua Guo,Zhenyu Lin,Xiaohua Jiang,Bin Qiu,Guonan Chen
A fluorescent biosensor for ochratoxin A was fabricated on the basis of a new nanocomposite (Fe 3 O 4 /g-C 3 N 4 /HKUST-1 composites). Fe 3 O 4 /g-C 3 N 4 /HKUST-1 was synthesized in this work for the first time, which combined HKUST-1 with g-C 3 N 4 to improve its chemical stability. Fe 3 O 4 /g-C 3 N 4 /HKUST-1 composites have strong adsorption capacity for dye-labeled aptamer and are able to completely quench the fluorescence of the dye through the photoinduced electron transfer (PET) mechanism. In the presence of ochratoxin A (OTA), it can bind with the aptamer with high affinity, causing the releasing of the dye-labeled aptamer from the Fe 3 O 4 /g-C 3 N 4 /HKUST-1 and therefore results in the recovery of fluorescence. The fluorescence intensity of the biosensor has a linear relationship with the OTA concentration in the range of 5.0–160.0 ng/mL. The LOD of sensor is 2.57 ng/mL (S/N=3). This fluorescence sensor based on the Fe 3 O 4 /g-C 3 N 4 /HKUST-1 composites has been applied to detect OTA in corn with satisfying results.
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ANALYTICA CHIMICA ACTA
·
2024
·
IF 5.7
Shaojie Ma,Yuchen Zhu,Boxin Chen,Bin Zhao,Fei Feng
Background The micro gas chromatography column (μGCC) is one of the key components of the miniaturized gas chromatography system. However, light alkanes are difficult to be separated by a micro gas chromatography column , especially for methane and ethane, because the length of μGCC is limited by the area of a silicon substrate. More importantly, the heterogeneous microchannel surface formed by silicon glass bonding causes uneven stationary phase coating and the forces between the untreated microchannel surfaces and the stationary phase materials are weak, which will prevent the improvement of separation performance. Results In this paper, a micro gas chromatography column (μGCC) with uniform HKUST-1 stationary phase is reported. Significantly, an alumina film prepared by the atomic layer deposition (ALD) technique is used to homogenize the heterogeneous microchannels. The alumina is a hydrophilic material and the alumina made by the ALD technique is uniform. The forces between hydrophilic alumina film and HKUST-1 are strong, which can greatly improve the coating uniformity of the hydrophilic stationary phase HKUST-1. The test results show that the μGCC could baseline separate the light alkane mixtures (CH 4 , C 2 H 6 , C 3 H 8 , and C 4 H 10 ) at the high testing temperature of 120 °C. The maximum resolution of the difficult-separated methane and ethane reached 19.2, which is 108 % higher than the μGCC using the same stationary phase without homogenizing the microchannel inner surface. Significance The μGCC uses ALD alumina film to homogenize the microchannel inner surface; meanwhile, hydrophilic ALD alumina has a strong electrostatic attraction with the hydrophilic stationary phase HKUST-1. Homogeneous microchannel surface and strong electrostatic attraction are favorable to obtain uniform stationary phase which greatly improves the separation performance, resulting in a large resolution for methane and ethane. The μGCC has broad application prospects in light alkane separation.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2024
·
IF 7.7
Guodong Chai,Ning Wang,Meiling Xu,Lina Ma,Xinglong Liu,Qiteng Ding,Shuai Zhang,Anning Li,Guofeng Xia,Yingchun Zhao,Wencong Liu,Dadong Liang,Chuanbo Ding
Bacterial infection, hyperinflammation and hypoxia, which can lead to amputation in severe cases, are frequently observed in diabetic wounds, and this has been a critical issue facing the repair of chronic skin injuries. In this study, a copper-based MOF (TAX@HKUST-1) highly loaded with taxifolin (TAX) with a drug loading of 41.94 ± 2.60 % was prepared. In addition, it has excellent catalase activity, and by constructing an oxygen-releasing hydrogel (PTH) system with calcium peroxide (CaO 2 ), it can be used as a nano-enzyme to promote the generation of oxygen from hydrogen peroxide (H 2 O 2 ) to provide sufficient oxygen to the wound, and at the same time, solve the problem of the oxidative stress damage caused by excess H 2 O 2 to the cells during the oxygen-releasing process. On the other hand, TAX and HKUST-1 in PTH synergistically promoted antimicrobial and anti-oxidative stress properties, and the bacterial inhibition rate against Staphylococcus aureus and Escherichia coli reached 90 %. In vivo experiments have shown that PTH hydrogel is able to treat diabetic skin repair by inhibiting the expression of inflammation-related proteins and promoting epidermal neogenesis, angiogenesis and collagen deposition.
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Biomicrofluidics
·
2020
·Vol. 14
·期 3
·
IF 2.504
Wu Qirui,Wang Xiaohong,Liu Jinfeng,Wu Jinbo,Zhang Yuan,Zhao Lijuan,Wen Weijia,Gong Xiuqing
Metal-organic frameworks (MOFs) have attracted considerable attention as novel nanoporous materials that combine the properties of organic and inorganic porous materials. HKUST-1 is one of the most well-developed and representative MOFs with wide applications in gas storage and separation, adsorption, and capture. In this study, we used microfluidics, an advanced technique of manipulation of small fluid volumes in microscale or even nanoscale channels, to investigate the effect of sodium dodecyl sulfate (SDS) on the growth of HKUST-1 crystals. We directly observed the morphological evolution of HKUST-1 crystals through droplet arrays with the SDS concentration gradient. The morphology of HKUST-1 evolved from cubic to cuboctahedron and finally to octahedron with increasing SDS concentration. The study results demonstrated the important role played by anions in solution in the structural regulation of HKUST-1.
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JOURNAL OF ENVIRONMENTAL MANAGEMENT
·
2025
·
IF 8.4
Jiantao Zhu,He Wen,Xiaofei Liu,Shuai Zhang,Jinkun Wang,Chunbo He,Wei Han,Yinghong Han,Dongying Yang,Na Song
Global climate change has been a serious issue, and the innovation of CO 2 reduction technologies has become a universal consensus and trend. The preparation of hierarchical porous metal-organic frameworks (MOFs) is an effective approach to improve CO 2 adsorption performance due to the accelerating the diffusion of gas flow and exposing more adsorptive pore surface. In this study, an innovative synthesis method that enlarges the pore size of HKUST-1 through utilizing nitrogen doped graphene quantum dots (NGQDs) was developed to induce defect formation during its self-assembly process. The mesoporous and total pore volume of HKUST-1@NGQDs-3 was 0.27 and 0.48 cm 3 /g, respectively, which was 58.8 % and 23.1 % higher than those of pure HKUST-1. The HKUST-1@NGQDs-3 exhibited high CO 2 adsorption capacity of 4.03 mmol/g at 1 bar, elevated up to 53.8 % compared to pristine HKUST-1 owing to its mesoporous structure. Importantly, the CO 2 /N 2 selectivity was significantly improved up to 31.7 % at 1 bar compared to HKUST-1. Additionally, the isosteric heat of adsorption for HKUST-1@NGQDs was lower than that of pure HKUST-1, facilitating the regeneration of adsorbent. This work presents a simple and efficient strategy for the developing MOFs-based composites for enhanced CO 2 capture.
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COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
·
2026
·
IF 5.4
Chunyu Zhao,Di Gao,Yuxuan Weng,Liquan Xiong,DongSheng Chen,Ying Wang
Size-controlled cubic–octahedral HKUST-1 is synthesized for modifying both inner and outer walls of hollow microtubes. • The Mn 3 O 4 -derived MnO 2 @HKUST-1 hollow composite micromotor integrates pollutant adsorption-enrichment with redox-mediated catalytic degradation within a unified platform. • Controlled HKUST-1 crystal size and deposition enabled uniform coating on hollow MnO₂ microtubes, enhancing pollutant enrichment while preserving catalytic sites and self-propulsion. In this study, cotton was employed as a biological template, and a size-controlled octahedral HKUST-1 structure was constructed via a combined calcination and hydrothermal process. Subsequently, a hollow tubular MnO 2 @HKUST-1 composite micromotor, derived from Mn 3 O 4 , was successfully fabricated. Under H 2 O 2 -driven conditions, the as-prepared micromotor exhibits stable autonomous motion and enables efficient removal of methylene blue (MB). Under optimized reaction conditions, a 90.4% removal efficiency was achieved within 10 min, and complete degradation was reached within 40 min. Kinetic and mechanistic analyses indicate that HKUST-1 primarily contributes to pollutant enrichment via its porous structure, whereas MnO 2 is responsible for H 2 O 2 activation and reactive oxygen species (ROS) generation. This work, for the first time, proposes a structural design principle for MOF-based micromotors that differs fundamentally from conventional MOF-coating strategies. Rather than improving performance by increasing MOF coverage or forming dense, continuous MOF coatings, the crystal size and deposition behavior of HKUST-1 were deliberately regulated to achieve a uniform yet non-continuous distribution over the inner and outer surfaces of hollow MnO 2 microtubes. This architecture simultaneously enhances pollutant enrichment, preserves the accessibility of MnO 2 catalytic sites, and maintains autonomous micromotor propulsion, thereby establishing a rational design principle for integrating adsorption, catalytic activity, and self-propulsion in multifunctional MOF-based environmental micromotors. Download: Download high-res image (318KB) Download: Download full-size image
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