ACS Applied Materials & Interfaces
·
2014
·
IF 5.9
Mufang Li,Haiying Li,Weibing Zhong,Qinghua Zhao,Dong Wang
The development of wearable electronics that can monitor human physiological information demands specially structured materials with excellent stretchability and electrical conductivity. In this study, a new stretchable conductive polypyrrole/polyurethane (PPy/PU) elastomer was designed and prepared by surface diffusion and in situ polymerization of PPy inside and on porous PU substrates. The structures allowed the formation of netlike microcracks under stretching. The netlike microcrack structures make possible the reversible changes in the electrical resistance of PPy/PU elastomers under stretching and releasing cycles. The variations in morphology and chemical structures, stretchability, and conductivity as well as the sensitivity of resistance change under stretching cycles were investigated. The mechanism of reversible conductivity of the PPy/PU elastomer was proposed. This property was then used to construct a waistband-like human breath detector. The results demonstrated its potential as a strain sensor for human health care applications by showing reversible resistance changes in the repeated stretching and contracting motion when human breathes in and out.
研究领域:
材料科学
·
可穿戴电子学
·
生物医学工程
·
传感器与执行器
·
高分子化学
✓ 已验证
DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2022
·
IF 16.744
Tianrui Cui,Yancong Qiao,Ding Li,Xiaorui Huang,Le Yang,Anzhi Yan,Zhikang Chen,Jiandong Xu,Xichao Tan,Jinming Jian,Zhen Li,Shourui Ji,Houfang Liu,Yi Yang,Xuegong Zhang,Tian-Ling Ren
With the advent of an aging society and increasing concern for cardiovascular health, comfortable long-term electrocardiographic (ECG) monitoring systems in daily life are much in demand. If the system can give real-time feedback on cardiovascular status and offer timely personalized advice like doctors, it will be beneficial to promote cardiovascular health and alleviate the imbalance of medical resources. Herein, we report a multifunctional, conformal, and air-permeable electronic skin (e-skin) based on MXene-Polyurethane mesh (MPM). When used as ECG electrodes, the e-skin shows ultra-low electrode–skin contact impedance (4.68 kΩ at 1 kHz), high signal-to-noise ratio (16.5 dB), and high breathability (2.1838 kg/m 2 /day), and can be continuously worn for at least 7 days. As a strain sensor, the e-skin exhibits a large measurement range (>40 %) and unique segmental sensitivity (GF = 172.54 in 0 ∼ 18.64 % and 79.38 in 18.64 ∼ 50 %), which is suitable for detecting both subtle and large physiological signals. More significantly, by combining the MPM e-skin with a flexible printed circuit board (FPCB) and a merged convolutional neural network & long-short-term memory (CNN & LSTM) intelligent algorithm, the acquired wearable intelligent e-skin system can realize daily 12-hour 12-lead ECG monitoring with diagnostic accuracy over 99 % for four arrhythmias. These results show that the MPM e-skin has huge potential in multifunctional intelligent healthcare systems. In particular, an intelligent ECG system similar to a “daily doctor” is proposed for daily long-term cardiovascular health monitoring.
研究领域:
生物医学工程
·
柔性电子学
·
心血管监测
·
智能医疗系统
·
转化医学
✓ 已验证
DOI
高影响因子
JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY
·
2018
·Vol. 316
·期 1
·411-417
·
IF 1.181
Wang Zhongtang,Wen Wei,Quan Wei,Du Liang,Wang Ping,Lin Jinxian,Xie Yun,Tan Zhaoyi
Plutonium is one of the key radionuclides in nuclear decommission. In this study, a rapid method was developed to analyze Pu for concrete samples using total digestion, CaF 2 /LaF 3 coprecipitation, extraction chromatography using TEVA and DGA resins, and ICP-MS measurement. The whole analytical process can be achieved within 2 days, with sufficiently high decontamination factors of interfering elements and high Pu chemical recovery (57–93%). The high throughput (22 samples/2 days) and low LODs (0.008 mBq g −1 for 239 Pu and 0.02 mBq g −1 for 240 Pu) allow this method to effectively detect low level Pu contamination in concrete samples.
研究领域:
分析化学
·
核科学与技术
·
环境科学
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
·
2021
·
IF 5.279
Yina Huang,Qin Yang,Xuan Mi,Liang Qiu,Xueying Tao,Zhihong Zhang,Jun Xia,Qinglong Wu,Hua Wei
Ripened Pu-erh tea (RPT) has been shown to be an effective natural ingredient to defend against experimentally induced colitis. We hypothesized that RPT would alleviate dextran sulfate sodium (DSS) induced colitis via modulating intestinal microbiota. The effect of RPT on mice gut microbiota was evaluated using 16S rRNA gene amplicon sequencing, broad-spectrum antibiotic (ABX) treatment, and fecal microbiota transplantation (FMT). Pretreatment with RPT enhanced intestinal barrier function, reduced colonic and serum proinflammatory cytokine and macrophage infiltration, and preserved the resilience of gut microbiota in mice during a DSS challenge. Administration of either RPT-regulated or healthy control-derived gut microbiota showed similar protection against colitis, and such protection could not be recapitulated with fecal microbiota from ABX-treated mice, suggesting a key role of protective consortium in the disease protection. Mechanistically, cecal contents of short-chain fatty acids (SCFAs) and colonic peroxisome proliferator activated receptor-γ (PPAR-γ) expression in colitis mice increased significantly by RPT intervention. Collectively, RPT treatment improved DSS-induced colitis by partially reversing the dysbiosis state of gut microbiota, which might be associated with an increase in SCFA level and PPAR-γ expression.
研究领域:
微生物学
·
免疫学
·
胃肠病学
·
药理学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
COMPOSITES COMMUNICATIONS
·
2024
·
IF 6.5
Yunlei Yin,Cheng Guo,Wanwan Li,Hongchen Liu,Qianqian Mu
Yarn-based strain sensors increasingly garner attention for their potential applications in intelligent wearable electronic devices. Developing highly elastic conductive composite yarns and integrating them into fabrics poses a significant challenge in manufacturing flexible electronic devices. In this study, a polyurethane (PU)/carbon nanotubes (CNTs) composite nanofiber yarn was successfully and continuously prepared using a simple conjugate spinning technique. The resulting yarn exhibited excellent mechanical properties, with a high tensile strength of up to 56.7 MPa and an elongation at break of 504 %. A yarn with a dual conductive network was created using CNTs ink dip-coating. It demonstrated excellent conductivity (8.77 S/cm), exceptional linear variation, and reusability. The sensor remained stable after 1000 cycles of testing, exhibiting a relative electrical resistance change of up to 594 % under a strain of 350 %. Additionally, taking advantage of the inherent knittability of one-dimensional yarn structures, a susceptible wearable textile-type strain sensor was successfully developed using textile knitting technology. This sensor can be directly attached to the surface of the human body for real-time monitoring of human body dynamics. This sensor showcases significant promise for use in flexible, intelligent, wearable electronic devices.
研究领域:
材料科学
·
生物医学工程
·
纺织工程
✓ 已验证
产品关联
DOI
高影响因子
LWT-FOOD SCIENCE AND TECHNOLOGY
·
2022
·
IF 6.056
Lijuan Ma,Yuxi Peng,Liping Du,Linqi Zhang,Wenzhe Tong,Yanru Weng,Dongguang Xiao,Huiling Zhang,Jihong Huang
As a typical Chinese tea, Pu-erh tea attracts much attention due to its unique flavor formed by taste and aroma compounds. To study the effects of taste compounds on the aroma release, model solutions containing five typical methoxyphenolic compounds (MCs) and main taste compounds with different concentrations were prepared based on the analysis of Pu-erh tea samples. GC-MS results indicated that the release of five MCs was inhibited by theabrownin, tea polysaccharide, tea polyphenol and catechins. The release of 1,2-dimethoxybenzene, 3,4-dimethoxytoluene and 1,2,3-trimethoxy-5-methyl-benzene was promoted by gallic acid under a low concentration (≤4 mg/g). Statistically, gallic acid had the most significant effect on the release of MCs. Isothermal titration calorimetry suggested that hydrogen bonds and hydrophobic effects had potential contributions to the interaction between taste and aroma compounds. This work will provide the research basis for revealing the formation mechanism of tea flavor.
研究领域:
食品科学
·
化学
·
农业科学
✓ 已验证
产品关联
DOI
高影响因子
Bioactive Materials
·
2022
·
IF 16.874
Limei Li,Qing Li,Li Gui,Yi Deng,Lu Wang,Jianlin Jiao,Yingrui Hu,Xiaoqian Lan,Jianhong Hou,Yao Li,Di Lu
Wound healing is a highly orchestrated process involving a variety of cells, including immune cells. Developing immunomodulatory biomaterials for regenerative engineering applications, such as bone regeneration, is an appealing strategy. Herein, inspired by the immunomodulatory effects of gastrodin (a bioactive component in traditional Chinese herbal medicine), a series of new immunomodulatory gastrodin-comprising biodegradable polyurethane (gastrodin-PU) and nano-hydroxyapatite (n-HA) (gastrodin-PU/n-HA) composites were developed. RAW 264.7 macrophages, rat bone marrow mesenchymal stem cells (rBMSCs), and human umbilical vein endothelial cells (HUVECs) were cultured with gastrodin-PU/n-HA containing different concentrations of gastrodin (0.5%, 1%, and 2%) to decipher their immunomodulatory effects on osteogenesis and angiogenesis in vitro . Results demonstrated that, compared with PU/n-HA, gastrodin-PU/n-HA induced macrophage polarization toward the M2 phenotype, as evidenced by the higher expression level of pro-regenerative cytokines (CD206, Arg-1) and the lower expression of pro-inflammatory cytokines (iNOS). The expression levels of osteogenesis-related factors (BMP-2 and ALP) in the rBMSCs and angiogenesis-related factors (VEGF and BFGF) in the HUVECs were significantly up-regulated in gastrodin-PU/n-HA/macrophage-conditioned medium. The immunomodulatory effects of gastrodin-PU/n-HA to reprogram macrophages from a pro-inflammatory (M1) phenotype to an anti-inflammatory and pro-healing (M2) phenotype were validated in a rat subcutaneous implantation model. And the 2% gastrodin-PU/n-HA significantly decreased fibrous capsule formation and enhanced angiogenesis. Additionally, 2% gastrodin-PU/n-HA scaffolds implanted in the rat femoral condyle defect model showed accelerated osteogenesis and angiogenesis. Thus, the novel gastrodin-PU/n-HA scaffold may represent a new and promising immunomodulatory biomaterial for bone repair and regeneration.
研究领域:
生物医学工程
·
组织工程
·
免疫学
·
材料科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
MECHANICS OF ADVANCED MATERIALS AND STRUCTURES
·
2023
·
IF 2.8
Mei Deng,Xuejuan Cao,Zhen He,Kuiling Wei,Boming Tang
The effect of filler modification on polyurethane (PU) properties was investigated by experimental and molecular dynamics simulation. Ultra-thin wearing course (PUTWC) was prepared using PU composite as a binder. The results indicated that, compared with composite with mineral powder, the tensile strength and elongation at break of PU composite (PUNC) containing CaCO3 increased by 32.7% and 15.8%, also exposed an appropriate viscosity. Stronger interaction energy and smaller free volume distribution existed in PUNC interface, which was obviously related to the PU soft segment. Additionally, prepared PUTWC using the single-layer paving method and PUNC of 1 kg. (m2)−1 showed high-skid resistance.
研究领域:
材料科学
·
化学工程
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF ENVIRONMENTAL RADIOACTIVITY
·
2023
·
IF 2.3
Yao Yang,Maoyi Luo,Yang Wu,Ni Yuan,Jingjing He,Hongmei Guo,Quan an
A reliable and stable method was developed to accurately analyze neptunium ( 237 Np) and plutonium isotopes in environmental samples using 242 Pu or 236 Pu as a tracer. Key parameters, including the valence adjustment conditions and the stabilities of Pu and Np in the different resins, were investigated using TK200 and TEVA resin. It was found that Pu and Np could be efficiently extracted simultaneously using TK200 resin under the optimal loading conditions (6–12 M HNO 3 ) with the addition of 0.01–0.12 M NaNO 2 for valence adjustment. These isotopes were subsequently stripped out using a solution containing 0.1 M HCl , 0.05 M HF, and 0.01 M NH 2 OH·HCl. The separation efficiencies of Pu and Np were >93%, and the chemical yield ratio between Np and Pu was maintained steady at an average of 1.00 ± 0.03 (n > 50) under the optimal conditions. The analytical method was validated by analyzing environmental soil samples spiked with known amounts of 239 Pu and 237 Np standard solutions or certified reference materials. The measured values of 237 Np, 239 Pu, and 240 Pu obtained by inductively coupled plasma tandem mass spectrometry were consistent with their International Atomic Energy Agency literature values within a 95% confidence interval. These results confirm the reliability and high analytical precision (<6%) of this developed method using Pu as a non-isotopic tracer for monitoring the chemical yield of 237 Np. The developed method can also be used for environmental pollutant monitoring and for tracer studies of the 237 Np and Pu isotopes.
研究领域:
环境科学
·
核化学
·
分析化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ACS Applied Materials & Interfaces
·
2015
·
IF 6.723
Limei Li,Yi Zuo,Qin Zou,Boyuan Yang,Lili Lin,Jidong Li,Yubao Li
To improve the mechanical properties of bone tissue and achieve the desired bone tissue regeneration for orthopedic surgery, newly designed hydroxyapatite/polyurethane (HA/PU) porous scaffolds were developed via in situ polymerization. The results showed that the molecular modification of PU soft segments by glyceride of castor oil (GCO) can increase the scaffold compressive strength by 48% and the elastic modulus by 96%. When nano-HA (n-HA) particles were incorporated into the GCO–PU matrix, the compressive strength and elastic modulus further increased by 49 and 74%, from 2.91 to 4.34 MPa and from 95 to 165.36 MPa, respectively. The n-HA particles with fine dispersity not only improved the interface bonding with the GCO–PU matrix but also provided effective bioactivity for bonding with bone tissue. The hierarchical structure and mechanical quality of the n-HA/GCO–PU composite scaffold were determined to be appropriate for the growth of cells and the regeneration of bony tissues, demonstrating promising prospects for bone repair and regeneration.
研究领域:
生物材料学
·
组织工程学
✓ 已验证
DOI
PubMed
高影响因子
INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
·
2024
·
IF 3.8
Huan Zhang,Hui Zhao,Tao Wang
High sensitivity, good mechanical property, and durability are critical parameters to value piezoresistive sensing performance, which highly rely on the interfacial interaction between the conductive filler and the polymer matrix. Using polydopamine (PDA) to improve the interfacial interaction is the usually adopted manner. However, unsatisfactory sensing performance is afforded, resulting from the formation of inhomogeneous deposition of PDA on the polymer matrix. In this work, for the first time, a piezoresistive sensor comprising anisotropic PU foam with a tightly adhered MXene conductive layer (MXene@PU) is fabricated by microwave sintering. The strong interfacial adhesion induced by microwave sintering coupled with the stress–strain amplification effect imparted by the aligned parallel channels of the directional TPU foams results in trinity excellence in sensitivity, mechanical performance, and durability. As a result, the as-fabricated sensor delivers a high sensitivity of 0.109 kPa–1, an impressive gauge factor of 7.78, and an excellent mechanical property with a compressive strength of 1603 kPa at 80% strain, which is 11.1 times, 16.2 times, and 1.6 times that of PDA-treated traditional ones, respectively. Moreover, superior durability is demonstrated for the MXene@PU foam sensor even under macropressure or macrostrain, which is a big challenge for conductive nanomaterial-coated polymer matrix-derived sensors. This novel approach provides a practical methodology for architecting a high-performance piezoresistive sensor that is very attractive in the intelligent sensing field.
研究领域:
材料科学
·
传感器技术
·
纳米技术
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF ELECTRONIC MATERIALS
·
2024
·
IF 2.2
Hong Zhen,Xing Yun,Xue Mingshan,Yang Dan,Luo Yidan,Yin Zuozhu,Xie Chan
Owing to their excellent thermal conductivity (TC), boron nitride nanosheet (BNNS)-filled polymer composite films have aroused great interest in their use for heat dissipation in the electronics industry. However, the application of BNNS composite films is limited by their lack of hydrophobicity and non-fouling properties, as well as their low corrosion resistance, affecting their long-term stability in specific environments, such as high humidity environment, rainwater erosion, corrosion from pollutants, and dust pollution. In this work, a composite film with both superhydrophobicity and a high TC was constructed by spraying a silicon carbide (SiC) and polyurethane (PU) coating modified by perfluorooctylmethoxysilane (PFTMS) onto the surface of BNNS-filled polymer composite films. The PFTMS coupling agent not only improved the dispersibility of SiC in PU and the combination of SiC with PU, but also reduced the surface free energy of the film. The optimal mass ratio of SiC to PU for the SiC/PU composite coating was 1.2:1, resulting in superhydrophobic properties with a contact angle (CA) of 168.6 ± 1.3° and a rolling angle (RA) of 2.8 ± 1.2°. Meanwhile, SiC with higher TC also allowed the BNNS-filled composite films to maintain a high TC (32.3 W/m K). The composite films exhibited excellent TC and self-cleaning ability, as well as improved mechanical and chemical stability of the surface, which provides a strategy for enhancing the environmental adaptability of BNNS composite films and broadening their application scenarios. Graphical Abstract Superhydrophobic SiC/PU-coated BNNS composite films with excellent anti-fouling properties and high thermal conductivity
研究领域:
材料科学
·
表面工程
·
热管理技术
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）