BIOMACROMOLECULES
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2023
·
IF 6.2
Shuang Qi,Bo Jiang,Caoxing Huang,Yongcan Jin
With the rapid increase of diabetes cases in the world, there is an increasing demand for slowing down and managing diabetes and its effects. It is considered that a viable prophylactic treatment for type 2 diabetes mellitus (T2DM) is to reduce carbohydrate digestibility by controlling the activities of α-amylase and α-glucosidase to control postprandial hyperglycemia and promote the growth of intestinal beneficial bacteria. In this work, the effects of sulfonated lignin with different sulfonation degrees (0.8 mmol/g, SL1; 2.9 mmol/g, SL2) on the inhibition of α-amylase and α-glucosidase and the proliferation of intestinal beneficial bacteria in vitro were investigated. The results showed that both SL1 and SL2 can inhibit the activity of α-amylase and α-glucosidase. The inhibition capacity (IC50, 32.35 μg/mL) of SL2 with a low concentration (0–0.5 mg/mL) to α-amylase was close to that of acarbose to α-amylase (IC50, 27.33 μg/mL). Compared with the control groups, the bacterial cell concentrations of Bifidobacteria adolescentis and Lactobacillus acidophilus cultured with SL1 and SL2 increased in varying degrees (8–36%), and the produced short-chain fatty acids were about 1.2 times higher. This work demonstrates the prospect of sulfonated lignin as a prebiotic for the prevention and treatment of T2DM, which provides new insights for opening up a brand new field of lignin.
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JOURNAL OF COLLOID AND INTERFACE SCIENCE
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2022
·
IF 9.965
Huaiwei Zhang,Yifan Chen,Liang Bao,Jing-yuan Ge
The green synthesis process of photocatalytic ammonia production has received more and more attentions. Herein, a Z-scheme heterojunction with all-solid-state structures is constructed, in which carbon dots can act as electron transferring mediators. The photocatalytic measurement shows that the modified photocatalysts exhibit much higher activities, in which the ammonia production rates can reach above 232 µmol·g cal -1 ·h −1 under the light irradiation. The improved catalytic properties can be credited to the significantly increased number of photoinduced oxygen vacancies, the excellent visible-light adsorption abilities and photogenerated electron-hole separation efficiencies for the carbon dots bridged heterostructures. More hydroxyl and superoxide radicals can be simultaneously produced in the composites. This work provides reasonable guidance for applications in photocatalytic ammonia synthesis and a promising construction strategy of efficient Z-scheme photocatalysts.
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Materials
·
2023
·Vol. 16
·期 4
·1568
·
IF 3.4
Feng Wang,Yaoqi Gu,Jianrui Zha,Shuya Wei
Ca(OH)2nanoparticles are effective materials for cultural heritage restoration, hazardous substance absorption and photocatalyst. However, many methods are complex, and the particle sizes are usually above 80–100 nm, involving mediocre efficacy for application in the stone restoration field. In this work, Nano Ca(OH)2with diameters less than 70 nm and composited with Graphene Quantum Dots (GQDs) were successfully synthesized in aqueous media. The morphology and structure of the nanoparticles were investigated with TEM, HRTEM, XRD, Raman and FTIR. The particle size distribution and relative kinetic stability of the Ca(OH)2in ethanol were performed using a laser particle size analyzer and spectrophotometer. Firstprinciple calculations based on the spin-polarized density functional theory (DFT) were carried out to study the reaction process and combination model. The nanoparticles, as prepared, are composed of primary hexagonal crystals and high ammoniated precursors, which have a positive effect on reducing the grain size, and interacted with the GQDs hybrid process. According to the First-principle calculations results, the energy variation of the whole reaction process and the bonding mode between Ca(OH)2and GQDs can be understood better.Keywords:Ca(OH)2;Graphene Quantum Dots;DFT;complex;nanoparticles
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Microorganisms
·
2023
·Vol. 11
·期 12
·2954
·
IF 4.5
Shufang Sun,Nawen Tang,Kun Han,Qunqing Wang,Qian Xu
Applying plant-derived fungicides is a safe and sustainable way to control wheat scab. In this study, volatile organic compounds (VOCs) of wheat cultivars with and without the resistance geneFhb1were analyzed by GC-MS, and 2-phenylethanol was screened out. The biocontrol function of 2-phenylethanol onFusarium graminearumwas evaluated in vitro and in vivo. Metabolomics analysis indicated that 2-phenylethanol altered the amino acid pathways ofF. graminearum, affecting its normal life activities. Under SEM and TEM observation, the mycelial morphology changed, and the integrity of the cell membrane was destroyed. Furthermore, 2-phenylethanol could inhibit the production of mycotoxins (DON, 3-ADON, 15-ADON) byF. graminearumand reduce grain contamination. This research provides new ideas for green prevention and control of wheat FHB in the field.Keywords:2-phenylethanol;Fusarium graminearum;volatile organic compounds (VOCs);antifungal mechanism;metabolomics
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COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
·
2023
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IF 5.2
Yidi Teng,Xiaoke Wei,Bingshu Wu,Yanmin Liu,Naixuan Fan,Yueyu Ma,Fengxiang Wang,Xiangyu Dou,Xifeng Yang,Weiwei Zhang
Developing eco-friendly coatings is crucial for protecting the surface of carbon steel , and particularly important is the development of chemically stable, durable, and highly stable superhydrophobic coatings which have become a growing trend. In this study, a hydrophobic nano-composite coating was synthesized, which consists of 2-methylimidazolezincsalt (ZIF-8) particles stabilized in cross-linked TEOS and coated with micro/nano-sized silica . Electrochemical experiments and surface analysis were conducted to evaluate the electrochemical behavior and interaction mechanism between ZIF-8 @SiO 2 /APTES/EP and Fe. The results showed that ZIF-8 @SiO 2 /APTES/EP has excellent inhibition performance in 3.5 wt% NaCl solution with inhibition efficiency up to 99.99%. Even after soaking for 72 h, the impedance modulus remains at 6 orders of magnitude, demonstrating excellent anti-corrosion performance. SEM and contact angle analysis demonstrated that a dense ZIF-8 @SiO 2 /APTES/EP film was formed on the mild steel surface, which has good corrosion resistance and chemical stability. This study is of great significance for guiding the design of high-performance hydrophobic coatings and meets the requirements of various industries for corrosion protection of mild steel surfaces.
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International Journal of Electrochemical Science
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2023
·
IF 1.5
Yuwan Tian,Cheng Wen,Chaofang Dong,Gui Wang,Peichang Deng,Guanting Zhou
A low pH-triggered intelligent corrosion inhibitor based on BTA loaded poly(2-diethylaminoethyl methacrylate) (PDEAEMA) microspheres was designed to prevent metal corrosion in a variable pH environment. The average particle size of the microspheres was 3 μm. The microspheres swelled at low pH values and shrank at high pH values, which guarantees pH sensitivity. The BTA release from the intelligent corrosion inhibitor depends on the environment pH value. The electrochemical results revealed that the intelligent corrosion inhibitor exhibited smart and efficient corrosion inhibition performance on steel corrosion, which was attributed to the pH-dependent supply of BTA.
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COLORATION TECHNOLOGY
·
2023
·Vol. 140
·期 2
·300-312
·
IF 1.8
Jianing Fan,Shouying Wu,Zixian Wang,Minglong Zheng,Miaomiao Zhang,Linping Zhang,Yi Zhong,Xiaofeng Sui,Hong Xu,Zhiping Mao
The discharge of coloured textile printing and dyeing wastewater causes environmental pollution. Disposing of wastewater efficiently, simply and with low consumption, is a problem that must be addressed. Herein, a catalytic method for rapid decolorisation of organic dyes was devised employing a terpyridine iron complex to activate oxidised permonosulphate. CI Acid Red 1 was used as the simulated pollutant, the influences of operating parameters on the fading effects of wastewater were explored. According to the results, the produced catalytic system exhibits a universal catalytic effect. Even when the dye concentration reaches 76.4 mg/L, the dyeing wastewater may be effectively decolorised. In addition, when anions (HCO 3 − , SO 4 2− , Cl − ) were present in the solution, the degradation effect of CI Acid Red 1 was still effective. Interestingly, active species such as sulphate radicals and singlet oxygen were detected in the catalytic degradation system by radical capture experiments. The removal rate of total organic carbon can achieve a percentage of 26.22% in 2 hours. This research provides a unique, enzyme-like catalytic system for the rapid breakdown of dye contaminants.
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ACS Applied Materials & Interfaces
·
2022
·
IF 10.383
Lina Wu,Xinjie Wang,Xiangchuan Wu,Shiqi Xu,Ming Liu,Xizhong Cao,Taishan Tang,Xingxu Huang,He Huang
The CRISPR-Cas system was developed into a molecular diagnostic tool with high sensitivity, low cost, and high specificity in recent years. Colorimetric assays based on nanozymes offer an attractive point-of-care testing method for their low cost of use and user-friendly operation. Here, a MnO2 nanozyme-mediated CRISPR-Cas12a system was instituted to detect SARS-CoV-2. MnO2 nanorods linked to magnetic beads via a single-stranded DNA (ssDNA) linker used as an oxidase-like nanozyme inducing the color change of 3,3′,5,5′-tetramethylbenzidine, which can be distinguished by the naked eye. The detection buffer color will change when the Cas12a is activated by SARS-CoV-2 and indiscriminately cleave the linker ssDNA. The detection limit was 10 copies per microliter and showed no cross-reaction with other coronaviruses. The nanozyme-mediated CRISPR-Cas12a system shows high selectivity and facile operation, with great potential for molecular diagnosis in point-of-care testing applications.
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BIOMEDICINE & PHARMACOTHERAPY
·
2022
·
IF 7.419
Zhiqi Zhao,Yizhang Chen,Xiaoqiong Li,Liying Zhu,Xin Wang,Li Li,Haibiao Sun,Xiaoqiang Han,Jinjun Li
To verify the role of myricetin in alleviating the symptoms of type 2 diabetes and regulating the intestinal flora, we established a type 2 diabetes mouse model. After being fed a high-fat and high-sugar diet for six weeks, mice were intraperitoneally injected with streptozotocin (80 mg/kg body weight [BW]) 2–3 times. Type 2 diabetes mice were randomly divided into type 2 diabetes control (T2DM) and myricetin intervention groups. Water and food intake, fasting blood glucose (FBG), and BW were monitored weekly. After six weeks of myricetin administration, superoxide dismutase (SOD) levels and blood lipid content were measured. Furthermore, 16S rRNA sequencing was used to detect the gut microbiota composition. FBG and blood lipid levels of T2DM mice were significantly reduced upon myricetin treatment, while SOD levels were increased. Myricetin improved polydipsia, polyphagia, polyuria, and weight loss in T2DM mice. In addition, the signature type 2 diabetes microflora was established by analyzing the microflora structure of healthy mice, type 2 diabetes mice, and mice treated with myricetin. Results showed that type 2 diabetes disrupted the mice intestinal flora, and myricetin intervention normalized the intestinal flora. In conclusion, our results indicate that myricetin alleviates type 2 diabetes in mice and regulates the intestinal microflora.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2022
·
IF 8.025
Weibo Zhang,Shucheng Zhang,Chong Chen,Ning Liu,Dong Yang,Pengjie Wang,Fazheng Ren
Pea albumin (PA) can reach the intestine in the active form because it is highly resistant to gastric acid and proteolytic enzymes after their oral intake, which can supply various bioactivities. However, there is no detailed knowledge of the intestinal cell uptake about PA. The aim of this work was to study the internalization mechanism and intracellular trafficking route of PA. The uptake of PA-cyanine 5.5 NHS ester (Cy5.5) was a time-dependent and concentration-dependent process in Caco-2 cells. Endocytosis inhibitors or small interfering RNA (siRNA) techniques revealed that the internalization of PA-Cy5.5 was energy-dependent and mediated by caveolin-mediated endocytosis. Furthermore, we observed colocalization of PA-Cy5.5 and its subcellular localization in Caco-2 cells by using confocal laser scanning microscopy, which revealed that the intracellular trafficking process of PA-Cy5.5 was related to endoplasmic reticulum, Golgi, and lysosome. Interestingly, PA can alleviate lipopolysaccharide -induced ER stress, which may be the main reason why pea albumin is anti-inflammatory. Overall, our findings suggest caveolin may be critical for PA uptake in enterocytes and could contribute to explore the bioactivities mechanism of pea albumin in body.
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JOURNAL OF ALLOYS AND COMPOUNDS
·
2022
·
IF 6.371
Wenhui Wang,Ruikang Zhang,Xiaoru Gao,Borong Yu,Zhan-gang Han,Yuanzhe Gao
Nickel and cobalt phosphates as a kind of low-cost inorganic materials are promising electroactive materials. The structure stability and good dispersibility of micro-spherical materials make them popular in the energy storage field. Therefore, the fabrications of Ni–Co phosphate microspheres with some facile and cost-effective methods have attracted lots of attentions. In this work, we present one-step growth of Ni 2 Co(PO 4 ) 2 microspheres using urea as pH regulator. Urea decomposes into NH 3 and CO 2 during the hydrothermal reaction process, resulting in the precipitation of Ni–Co phosphates. The as-prepared Ni 2 Co(PO 4 ) 2 microspheres exhibit uniform and well-dispersed spherical morphology. Compared with traditional Ni 2 Co(PO 4 ) 2 particles, Ni 2 Co(PO 4 ) 2 microspheres exhibit larger electrochemical specific surface area and smaller resistance of electrons/ions transfer. The specific capacity of Ni 2 Co(PO 4 ) 2 microspheres reaches as high as 153 mAh g - 1 at a current density of 1 A g - 1 , which is 1.59 times higher than that of traditional Ni 2 Co(PO 4 ) 2 particles. In addition, this facile one-step synthetic method can be applied to fabricate series of Ni–Co phosphates with different Ni/Co atomic ratios. This work provides a facile synthetic method of fabricating Ni–Co phosphate materials, which has potential applications in large-scale manufacture.
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Sustainable Energy & Fuels
·
2022
·Vol. 6
·期 4
·1156-1163
·
IF 6.813
Guangzhi Ren,Guangyi Li,Ying Zhang,Aiqin Wang,Xiaodong Wang,Yu Cong,Tao Zhang,Ning Li
Jet fuel and diesel range C12 and C17 cycloalkanes were synthesized for the first time by a two-step process with 2-methylfuran and benzaldehyde, two platform compounds which can be derived from lignocellulose. In the first step, 5,5′-(phenylmethylene)bis(2-methylfuran) was obtained by the acid-catalyzed hydroxylalkylation/alkylation (HAA) of 2-methylfuran and benzaldehyde. Among the investigated commercial acidic resins, Nafion resin demonstrated the highest activity for the HAA of 2-methylfuran and benzaldehyde, which can be rationalized by the highest acid strength of Nafion resin. In the second step, the 5,5′-(phenylmethylene)bis(2-methylfuran) from the HAA reaction was further hydrodeoxygenated to jet fuel and diesel range C12 and C17 cycloalkanes. Among the investigated catalyst systems, the combination of H-ZSM-5 and Ru/hydroxyapatite (denoted as H-ZSM-5 + Ru/HAP) exhibited the best hydrodeoxygenation (HDO) performance. Over it, a high total carbon yield (87.3%) of jet fuel and diesel range C12 and C17 cycloalkanes was obtained under mild conditions (453 K and 4 MPa H2). According to our measurements, the mixture of C12 and C17 cycloalkanes obtained from the HDO process has high density (0.816 g mL−1) and low freezing point (240 K). Therefore, it can be blended into current bio-diesel and bio-jet fuel to increase their volumetric heat values. As another option, the C12 and C17 cycloalkanes can also be dehydrogenated to produce alkylbenzenes that can be used as feedstock in the production of surfactants.
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