JOURNAL OF NANOBIOTECHNOLOGY
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2026
·Vol. 24
·期 1
·145
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IF 12.6
Zhao Jianguo,Lou Wanqing,Wang Yixin,Wang Lu,Jin Xiaoqian,Wang Chenyang,Yao Jiangmeng,Zhang Jinjin,Zhuang Wenjuan,Wei Jiayi,Lin Dajun,Guo Yishun,Shao Yi,Wang Bailiang,Jiang Zipei
During keratitis treatment, oxidative stress and inflammation often result in corneal neovascularisation, scarring, and reduced light transmittance. In this study, single-atom Pt/CeO 2 is synthesized, exhibiting significantly enhanced catalase-like and superoxide dismutase-like activities for the elimination of superoxide anions (•O 2 − ), hydrogen peroxide (H 2 O 2 ), and hydroxyl radicals (•OH). Doping single-atom Pt onto CeO 2 increases the Ce 3+ concentration in the Ce 3+ /Ce 4+ ratio from 39.12% to 58.66%, as confirmed by electron spin resonance, high-resolution transmission electron microscopy, X-ray photoelectron spectroscopy, and Raman spectroscopy. In vitro studies demonstrate that single-atom Pt/CeO 2 effectively reduces intracellular ROS levels in H 2 O 2 -activated human corneal epithelial cells. Additionally, it exerts an anti-inflammatory effect on LPS-stimulated RAW264.7 macrophages, significantly decreasing the expression of interleukin-1β, interleukin-6, and tumour necrosis factor-α. In vivo, in an LPS-induced keratitis animal model, single-atom Pt/CeO 2 accelerates corneal ulcer healing and preserves corneal light transmittance, attributed to its anti-inflammatory properties, enzyme-like activities, and ability to promote cell migration. This study offers a novel approach for treating various inflammatory and autoimmune diseases. Graphical
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COLLOID AND POLYMER SCIENCE
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2026
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IF 2.3
Zhang Hongmei,Wang Pengge,Yang Yunxia,Zhu Daliang,Wang Yanqing
Succinoglycan riclin (RIC), a natural polysaccharide with diverse biological activities, was employed as a drug carrier to construct a novel nanoplatform. Polysaccharide-Pt(IV) conjugates were synthesized via esterification between the hydroxyl groups of RIC and a Pt(IV) prodrug, which was subsequently loaded with resveratrol (RES) to form the RES@RIC-Pt(IV) nanoplatform. The successful synthesis and physical properties of the complex were confirmed through multiple characterization techniques. Pt(IV) was significantly bonded to the polysaccharide chain. The drug loading capacities for platinum and RES were quantified using ICP-OES and UV–Vis spectrophotometry, respectively. The percentage of Pt content in RIC-Pt (IV) conjugates can be calculated as 11.71%. In vitro cytotoxicity assays revealed that the RES@RIC-Pt(IV) platform exhibited significantly enhanced toxicity against HepG2 and LO2 cancer cell lines compared to individual small-molecule drugs. These results demonstrate that this multi-drug delivery system achieves a potent synergistic anticancer effect, highlighting its potential for improved cancer therapy. Graphical abstract
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FULLERENES NANOTUBES AND CARBON NANOSTRUCTURES
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2018
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IF 1.011
Xingfeng Zhang,Qiujie Wu,Zhongyi Du,Yanmei Zheng,Qingbiao Li
The g-C3N4-Pt photocatalyst was successfully prepared by the combination of a biosynthesis method and sol deposition, which were used for hydrogen evolution from water splitting. The layers of g-C3N4 are thinned and the Pt nanoparticles simultaneously become tightly bound to g-C3N4 by secondary calcination in the process of synthesizing the g-C3N4-Pt photocatalyst. Analysis of the morphological structure and instrumental characterization of the optical performance revealed that the Pt nanoparticles were successfully loaded and well dispersed on the surface of g-C3N4. Furthermore, the absorption wavelength range of the g-C3N4-Pt photocatalyst in visible light was widened and the absorption increased. The activity and photostability of the g-C3N4-Pt photocatalyst for hydrogen evolution under visible light irradiation (λ≥420 nm) were excellent. The rate of H2 evolution reached 582.4 μmol h−1 g−1, and the quantum efficiency (QE) reached 2.70% at 420 nm.
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ELECTROCHIMICA ACTA
·
2018
·
IF 5.116
Lulu Yang,Yujin Ji,Fan Liao,Yafei Cheng,Yuyang Sun,Youyong Li,Mingwang Shao
Recently, much attention has focused on less platinum alternative materials serving as the counter electrode material for dye-sensitized solar cells, while platinum itself has a lot of room for improvement. Herein, we introduce the earth-abundant silicon and combine it with Pt nanoparticles as the counter electrode in dye-sensitized solar cells to enlarge surface area and enhance the activity of Pt. Si-H bonds can reduce metal ions and enable small metal nanoparticles grown on the surface of silicon nanowires, which can effectively prevent metal nanoparticles from agglomeration in the catalysis. The density functional theory (DFT) calculation shows that the adsorption energy of I atom on the Pt/Si interface is −0.8 eV, which is the optimal adsorption energy for triiodide reduction, indicating that Pt/Si is a perfect material for the counter electrode. The electrochemical characterizations and the photocurrent-voltage performance experimentally confirm that Pt/SiNW is a better counter electrode material than other metal/SiNW composites and Pt, which is in accordance with DFT calculations. The power conversion efficiency of device based on the Pt/SiNW electrode is higher than that of the device based on Pt (8.23% vs.7.93%).
研究领域:
材料科学
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纳米技术
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光伏学
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计算化学
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COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
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2026
·
IF 5.4
Huanming Wang,Jinqiao Hou,Chong Li,Xinge Cui,Chenze Lu,Fujian Ren,Chen Fu,Jingting Luo,Ran Tao
Non-invasive monitoring of exhaled isopropanol (IPA) is a promising route for diabetes management. However, current analytical methods are limited by inadequate sensitivity, low selectivity, and slow response times. In this work, we report a high-performance surface acoustic wave (SAW) gas sensor engineered with Pt-doped ZnO nanoparticle films synthesized via hydrothermal growth and spin-coating. The sensitive layer is optimized with 0.5 wt% Pt doping level, which enhances the specific surface area and pore structure uniformity. At room temperature (25°C), the sensor demonstrates exceptional performance, featuring highly selective IPA detection with a sensitivity of 6.76 Hz/ppm, fast response/recovery times of 12 s/12 s, a low detection limit of 1.38 ppm, and excellent reproducibility over 30 days of operation. Mechanistic studies confirm that the high selectivity is governed by a Pt-O coordination effect that facilitates preferential IPA adsorption. This work presents a robust and practical platform for diabetes monitoring and provides a clear strategy for the rational design of next-generation metal oxide-based gas sensors.
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Materials
·
2026
·Vol. 19
·期 1
·194
·
IF 3.2
Yu Gao,Lipeng Wang,Kun Li,Yongbo Ji
In this work, V-Pt-Ti catalysts were synthesized employing impregnation (IP), precipitation (PC), sol-gel (SG), thermal decomposition (TD), and hydrothermal (HD) methods. A systematic study has been carried out to investigate impacts of various preparation methods on the performance of NH3selective catalytic oxidation (SCO) at temperatures from 150 °C to 450 °C. N2adsorption/desorption, XPS, XRD, H2-TPR, NH3-TPD, O2-TPD, SEM, TEM, and in situ DRIFTS were adopted to characterize the physico-chemical property of V-Pt-Ti catalysts. The results suggested that V-Pt-Ti catalysts synthesized by precipitation methods (denoted as VPT-PC) exhibited notably better SCO performance across the 150–450 °C temperature range compared with those produced by impregnation (IP), sol-gel (SG), thermal decomposition (TD), and hydrothermal (HD) methods. The outstanding performance of the VPT-PC catalyst could be ascribed to its larger surface area, higher relative contents of Pt0, V5+, and Oα, more abundant surface acid sites, and better redox property. In situ DRIFTS results suggested that NO2species could participate in NH3oxidation reaction on the surface of the VPT-PC catalyst, which was beneficial for improving the SCO activity.
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Journal of Materials Chemistry A
·
2026
·
IF 9.2
Chonghan Xia,Junhao Ma,Qihang Chen,Yee Yan Tay,Lydia H. Wong,Kwan W. Tan
The synthesis of ordered mesoporous multimetallic alloys (MMAs) with controlled composition remains challenging due to disparate reduction kinetics of multimetal precursors. Here we report a one-pot nanocasting approach in which PtFeCoNiCu salts are co-infiltrated and co-reduced within a gyroidal KIT-6 mesoporous silica scaffold, followed by template removal and acid etching, yielding single phase fcc mesoporous alloys with a 3D bicontinuous network morphology. By tuning the reduction conditions, we regulate the incorporation of Fe, Co and Ni around a PtCu-rich solid-solution lattice and remove FeCoNi overgrowths, exposing an ordered Pt-based mesoporous framework with excellent HER performance. The optimized ordered MMA catalyst, delivers an overpotential of 25 mV at 10 mA cm−2, a Tafel slope of 49.1 mV dec−1, and negligible degradation over 100 000 cycles, outperforming both commercial Pt/C and mesoporous Pt controls. This work demonstrates a general route to compositionally tuned ordered mesoporous multimetallic solid-solution alloys suitable for catalysis, sensing and related functional materials.
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MICROCHIMICA ACTA
·
2026
·Vol. 193
·期 4
·233
·
IF 5.4
Gao Xiang,Hou Yujiao,Lin Fang,Wen Limei,Guo Yali,Kong Weijun,Hu Junping,Yang Jianhua
An electrochemical (EC) molecularly imprinted polymer (MIP) sensor for therapeutic drug monitoring of olanzapine (OLZ) has been developed. A “rime-like” gold-platinum nanostructured film (Au-Pt NF) was fabricated on a screen-printed carbon electrode (SPCE) via an one-step hydrogen bubble dynamic template (HBDT) method, followed by electropolymerization of a polyaniline-based MIP. The Au-Pt NF/SPCE served as an ideal three-dimensional conductive substrate with a large active area and enhanced electron-transfer capability, endowing the specific MIP sensor with high sensitivity. Using [Fe(CN) 6 ] 3−/4− as a redox probe, the sensor quantified OLZ by the decrease in differential pulse voltammetry current caused by target binding. It exhibited two linear ranges (0.005–0.4 µM and 0.4–10 µM) with a detection limit of 0.94 nM, and demonstrated high selectivity, reproducibility, and stability. The sensor achieved recoveries of 96.7–102.7% for OLZ in tablets, urine, and whole blood. This work provides a reliable, all-EC sensing platform with strong potential for rapid OLZ monitoring in clinical settings.
Section
Graphical
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Catalysis Science & Technology
·
2026
·
IF 4
Qin Zhao,Ruize Sun,Xiaonan Liu,Lexi Tang,Jingge Chen,Jicheng Zhou,Wentao Xu
Propane direct dehydrogenation (PDH) is an important way to prepare propylene (C3H6). However, the conventional thermal catalytic process often has the problems of high reaction temperature and side reactions such as carbon deposition, which makes it difficult to balance the conversion of C3H8 and the selectivity of C3H6. In this work, a new method for direct dehydrogenation of low-temperature and high-efficiency propane (C3H8) to C3H6 by microwave catalysis was proposed, and a Pt-Co/SiBeta+SiC microwave catalyst was developed. The results showed that microwave catalysis significantly improved the C3H8 conversion and C3H6 selectivity of the catalyst, and effectively reduced the reaction temperature. Under 450 °C lowtemperature microwave catalysis (MCRM), the initial conversion of C3H8 was as high as 50.4%, and the initial selectivity of C3H6 was as high as 97.2%. Both are significantly better than the 5.9% initial conversion and 95.6% initial selectivity under conventional thermal catalysis (CRM). It was further found that the microwave irradiation significantly reduced the apparent activation energy of the catalyst from 164.4 kJ•mol -1 under CRM to 68.4 kJ•mol -1 under MCRM. This work provides a new idea for the development of low-temperature and high-efficiency PDH catalytic system, and shows the application potential of microwave catalysis in light hydrocarbon conversion.
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ACS Sensors
·
2026
·
IF 10.9
Xinxin He,Ping Guo,Yinhua Hu,Xuyang An,Shuai Liang,Tiezhu Liu,Tong Zhang,Guohua Cai,Yanjie Chu,Jia Zhang
Exhaled human breath contains disease-related biomarkers, enabling non-invasive medical diagnostics. Small intestinal bacterial overgrowth (SIBO) is traditionally diagnosed through hydrogen measurement, a method that offers limited specificity and sensitivity. Herein, we introduce a simplified Pt/Pd-SnO2 electronic composed of using only two sensing materials to achieve multi-gas detection. By simultaneously monitoring H2, CO, ethanol, and acetone, the system provides a more informative diagnostic profile than conventional single-marker tests. Furthermore, the electronic nose employs dual operating temperatures (135 and 190 °C) to enhance gas discrimination. Machine learning-assisted signal processing further optimizes the system’s ability to differentiate gases, enabling more accurate detection in clinical settings. It achieves a 93% classification accuracy and a mean squared error of 0.78 for gas concentration estimation. Importantly, the system was validated using real clinical breath samples collected after lactulose ingestion, where SIBO patients exhibited markedly elevated responses (7.62−18.77) compared to healthy individuals (2.45−4.91). This clinically validated, multi-gas platform offers improved accuracy and practical potential for SIBO diagnosis.
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Chemical Science
·
2025
·
IF 7.4
Yundao Jing,Xiaohu Ge,Rui Song,Ningchao Zhu,Jinquan Ming,Nihong An,Yueqiang Cao,Gang Qian,Xuezhi Duan,Xing-Gui Zhou
Selective hydrogenation of amino acids to amino alcohols is a valuable transformation in the synthesis of pharmaceuticals, fine chemicals, and chiral building blocks. However, achieving high activity and selectivity under mild conditions remains challenging due to the need for simultaneous hydrogen activation and substrate coordination. Here, we report a series of Pt–MoO3 bifunctional catalysts for the hydrogenation of L-alanine (Ala) to alaninol (AlaOH), with a focus on tuning metal–oxide synergy. Structural and electronic characterization by high-angle annular dark-field scanning transmission electron microscopy, X-ray photoelectron spectroscopy and X-ray adsorption spectroscopy reveal strong Pt–MoO3 interactions, characterized by partial electron transfer. Catalytic tests reveal a volcano-type dependence on Pt/Mo ratio, with the 4-Pt-MoO3 catalyst achieving the highest performance. The experiments of H2 temperature programmed desorption and in-situ diffuse reflectance infrared Fourier transform spectroscopy combined with theoretical calculations support a bifunctional mechanism, in which Pt serves as the primary site for H2 activation, while MoO3 facilitates adsorption and stabilization of polar alanine. Further tuning via thermal treatments show that the moderate treatment at 500 °C optimally balances the redox state of MoO3 without compromising Pt dispersion, leading to enhanced hydrogenation performance. This work not only advances understanding of metal-oxide interfacial catalysis but also provides a rational design strategy for efficient and selective hydrogenation amino acid.
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Energies
·
2023
·Vol. 16
·期 9
·3684
·
IF 3.2
Ruimin Zhang,Ke Wang,Peng Wang,Yan He,Zhiming Liu
Single-atom catalysts (SACs) within carbon matrix became one of the most promising alternatives to noble metal-based catalysts for oxygen reduction reaction (ORR). Although SACs have significant benefits in reducing the total catalyst cost, it also has the disadvantages of weak interaction between atoms and poor stability. Hence, there is still much room for improvement for the catalyst activity. In response, we designed a Fe-Co-Pt ternary metal single atom catalyst anchored on covalent organic framework (COF)-derived N-doped carbon nanospheres (Pt, Fe, Co/N-C). Due to effective charge transfer between Pt single atom and neighboring Fe-Co components, an intense electron interaction can be established within the Pt, Fe, Co/N-C catalyst. This is beneficial for enhancing charge transfer efficiency, modulating d electronic structure of Pt center and weakening oxygen intermediate adsorption, thus distinctly accelerating ORR catalytic kinetics. As expected, the half-wave potential of Pt, Fe, Co/N-C was 0.845 V, much higher than those of commercial 20 wt% Pt/C (0.835 V), Pt/N-C (0.79 V) and Fe, Co/N-C (0.81 V) counterparts. Moreover, the Pt, Fe, Co/N-C catalyst demonstrated much-improved cycling stability and methanol tolerance.Keywords:oxygen reduction reaction;electrocatalysts;single atom;ternary metal;kinetics
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