INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
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2024
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IF 7.7
Dongxing Dong,Zhiqiang Cheng,Jingjing Zhang,Zhengyi Gu,Zhaolian Han,Wenli Hou,Xiaoli Lv
Pressure ulcer dressings with different functions can enhance wound healing ability to varying degrees; however, pressure ulcer dressings that integrate various functions and break the resistance of bacteria to traditional antibiotics have not been widely studied. We proposed a self-pumping/super-absorbent/transportable drug dressing (PLD-SLD), polycaprolactone (PCL)/sodium alginate (SA) was used to load platelet-derived growth factor (PDGF) and lidocaine hydrochloride (LID) by Janus electrospinning and self-assembly technology, and Ɛ-polylysine was used as a biological bacteriostatic agent to prepare a multi-layer dressing. SEM showed that the dressing had a fluffy structure. The dressing can pump the exudate to the SA layer away from the skin. The swelling ratio reached 1378.667 ± 44.752 %. Coagulate blood in 5 min. On the 8th day, the unclosed area rate of the PLD-SLD dressing group was 16.112 ± 0.088 % lower than that of the model group. Importantly, the dressing can induce the expression of CD31, VEGF, α-SMA, and reduce the expression of CD68, thereby giving priority to wound healing. There was no scar formation after healing. In this study, a new dressing preparation method was proposed for the problems of exudate management, infection control, pain relief and healing promotion of stage 3–4 pressure ulcer healing.
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FOOD HYDROCOLLOIDS
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2025
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IF 12.4
Yan Wen,Yan Zhang,Na Lü,Zehui Xuan,Lili Lu
D-tagatose is an attractive functional sweetener, and its production via enzymatic synthesis is simple and environmentally friendly; however, it faces challenges related to enzyme and substrate costs. In this study, a novel and cost-effective method for synthesizing D-tagatose was established using L-arabinose isomerase (L-AI) immobilized within a sodium alginate (SA) composite hydrogel, with the low-cost guar gum as the starting material. Eight inorganic or organic materials were individually combined with SA to encapsulate L-AI. The immobilized enzyme prepared with SA and 50-nm SiO 2 particles demonstrated superior properties, including enhanced mechanical strength and improved reusability, compared to enzymes immobilized with other carriers. The structure of the immobilized enzyme was characterized by scanning electron microscopy, Fourier-transform infrared spectroscopy, and X-ray diffraction. The D-tagatose synthesis reaction using the immobilized enzyme was optimized through both single-factor and statistical methods. The maximum yield of D-tagatose reached 30.12% from 1 M D-galactose at 68°C, with a productivity of 6.78 g/L/h. The immobilized enzyme was reusable for 20 cycles of reaction at 60°C, retaining over 55% of its initial activity and accumulating a high amount of 863.74 g/L D-tagatose. Furthermore, it efficiently converted guar gum hydrolysate into D-tagatose, retaining over 50% enzyme activity and yielding 114.32 g/L of D-tagatose after 10 cycles. The excellent enzyme reusability and the exploration of an economic substrate would significantly reduce production costs in large-scale D-tagatose synthesis in the future.
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Scientific Reports
·
2024
·Vol. 14
·期 1
·1-17
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IF 3.8
El-diehy Mahmoud A.,Farghal Ibrahim I.,Amin Mohamed A.,Ghobashy Mohamed mohamady,Nowwar Abdelatti I.,Gayed H. M.
The main focus of this study was on using radiation to make an ultra-absorbent hydrogel (UAH) from sodium alginate (SA) and gelatin (GL) biopolymers. This UAH can effectively handle water and nitrogen in wheat farming during drought stress. The hydrogel was synthesized by gamma irradiation-induced SA/GL/polyacrylamide crosslinking at 10–40 kGy. Varying SA/GL ratios affected swelling and the gel fraction of SA/GL/PAm hydrogels. The (SA/GL 17/83) hydrogel exhibited a 40.03 g/g swelling degree, while increasing SA content resulted in higher swelling, peaking at 75.5 g/g for (SA/GL 83/17). This indicated a synergistic interaction between SA and GL. The gel fraction also increased from 76.8 to 90.3%, with a higher GL content reflecting increased crosslinking. After multiple hydrolysis cycles, the hydrogel achieved 1293 (g/g) swelling and 36 days of water retention. When applied to wheat ( Triticuma estivum ) under drought stress, it significantly improved shoot length (18%), root length (43%), shoot fresh weight (49%), and shoot dry weight (51%) under extreme drought. The significant increases in protein and carbohydrate content in both shoots (up to 32% and 19%, respectively) and grains (up to 21% and 24%, respectively), along with the reduction in proline content (up to 38%), demonstrate that ultra-absorbent hydrogel (UAH) effectively enhances nitrogen content, photosynthesis, and overall plant health in wheat under varying drought stress levels. This novel SA/GL-based UAH holds promise for addressing water scarcity and agricultural challenges, offering a sustainable solution for water and nitrogen management under drought stress.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
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2025
·
IF 8.5
Huanggen Yang,Pei Zhang,Qi Zheng,Faisal Alresheedi,Saleem Raza,Duofu Li,Yan Sui,Mang Lu
In this work, an environmentally friendly method was employed to synthesize a composite hydrogel possessing superior photocatalytic capabilities for removal of volatile organic compound (VOC). TiNbC-MXene were synthesized by exfoliation of TiNbAlC-Maxphase, then TiNbC/VO 2 composites were synthesized by water bath heating synthesis method. After that, polydopamine was in situ deposited on the surface of TiNbC/VO 2 composites to synthesize TiNbC/VO 2 @PDA materials. Finally, the TiNbC/VO 2 @PDA composites were successfully incorporated in sodium alginate (SA) by titration and two-step composite cross-linking process to form TiNbC/VO 2 @PDA-SA. Its morphological properties and structure were investigated through a series of characterizations. This study further investigates the photocatalytic performance of TiNbC/VO 2 @PDA-SA for the degradation of six VOCs under UV-light. Toluene, Xylene, and Acetone achieved degradation efficiencies of 88.2 %, 91.6 %, and 94.3 %, respectively, following first-order kinetics. Vinyl Chloride, Isopropyl Alcohol, and Formaldehyde showed removal rates of 86.8 %, 90.3 %, and 92.6 %. A 30-min dark adsorption phase was critical for achieving equilibrium. Moreover, the proposed mechanism and quenching study indicate that hydroxyl and oxygen radicals play a key role in the degradation process. The materials also exhibited outstanding regeneration capability and maintained strong recyclability over ten successive cycles. Overall, the results confirm that TiNbC/VO 2 @PDA-SA is a highly efficient photocatalyst for VOCs removal.
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Food Packaging and Shelf Life
·
2025
·
IF 10.6
Yanyan Wang,Ruoran Qin,Jiayi Xue,Hui Li,Longwei Jiang
Succinate cyclodextrin/chitosan nanoparticles (SCC NPs) loaded with resveratrol (Res) were successfully synthesized by self-assembly. Nanocomposite films were prepared by adding R-SCC NPs to sodium alginate (SA). The structure, physical and chemical properties, and antioxidant, antibacterial and biodegradability properties of the nanocomposite films were characterized. Scanning electron microscopy (SEM) results revealed that R-SCC NPs in 1–6 % were uniformly distributed in the SA film matrix. FTIR analysis revealed that the R-SCC NPs formed intermolecular hydrogen bonds with SA. The maximum tensile strength of the nanocomposite film was 44.24 ± 0.82 MPa, which was 153.50 % of that of the SA film. The addition of R-SCC NPs markedly enhanced the UV absorption capacity, antioxidant stability, and antibacterial activity of the nanocomposite films. In addition, because Res was encapsulated in the SCC NPs, control over the release from the composite film was achieved. This film has excellent biodegradability in soil and can regulate the soil microbial community. Furthermore, the developed film package can effectively prolong the expiry date of blueberries, so the SA film containing R-SCC NPs as active packaging has significant potential for maintaining food quality.
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Energy Technology
·
2025
·
IF 3.6
Xiaogang Fu,Xinghao Wang,Wenting Zhang
Wearable self-powered sensors offer significant potential for real-time monitoring and behavioral assessment in personalized rehabilitation and neurodevelopmental interventions. In this work, a sodium alginate/silk (SA/silk) composite film–based triboelectric nanogenerator (SS-TENG) is developed for bio-mechanical energy harvesting and motion monitoring in traditional physical training programs for children with autism spectrum disorder. The SA/silk composite provides high mechanical flexibility and stable surface morphology, ensuring consistent triboelectric output during dynamic movements. The SS-TENG delivers a peak open-circuit voltage ( V OC ) of 195.3 V, short-circuit current ( I SC ) of 58.8 μA, and transferred charge ( Q SC ) of 174.5 nC, with a maximum power of 4.3 mW. Its output is highly sensitive to changes in force, frequency, and displacement, enabling precise detection of activity intensity. The device also demonstrates strong energy storage capability by effectively charging capacitors. When integrated into footwear, the SS-TENG enables battery-free, real-time monitoring of gait and movement. Notably, it distinguishes between neurotypical and autistic motor behaviors during walking, running, and jumping based on characteristic signal patterns. These results demonstrate the SS-TENG's potential as a wearable, self-powered platform for quantitative evaluation of sports-based interventions, supporting early diagnosis and personalized training in autism spectrum disorder therapy.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2025
·
IF 8.5
Huiying He,Shuai Zhang,Qiteng Ding,Chuanbo Ding,Junran Yang,Xiaoyu Bi,Xiaohang Sun,Dan Sun,Zhiqiang Cheng,Wencong Liu,Dadong Liang
Ulcerative colitis (UC) is a chronic inflammatory bowel disease, and its pathogenesis is closely related to the dysbiosis of intestinal microbiota and the excessive activation of the immune system. Research has shown that Lactobacillus spp. can alleviate UC by enhancing intestinal barrier function and modulating immune responses. However, the primary challenge lies in ensuring the targeted release and survival of Lactobacillus spp. This research aims to develop a drug delivery system comprising Lactobacillus reuteri strain C1/5R (L. r ) encapsulated in zeolitic imidazolate framework (ZIF)-67/sodium alginate (SA) hydrogel microspheres (L. r @ZIF/SA) to achieve targeted delivery of the probiotic to the colon. This study employed dihydrogenourea (taxifolin, TAX) as a pre-intervention to enrich Lactobacillus spp. in the intestinal tract of mice. SA was used as a matrix to encapsulate L. r and ZIF-67. The pH-sensitive characteristics of ZIF-67 enabled in situ crosslinking of SA in the stomach to form stable hydrogels. The hydrogels were converted into emulsion-processed microspheres with reduced particle size to facilitate gastric transit. The pH-dependent degradation of ZIF-67 in the intestine enabled the controlled release of L. r , which modulated the gut microbiota, exerted anti-inflammatory activities, and restored epithelial barrier function. This research overcomes limitations of UC in terms of low oral probiotic viability and antibiotic resistance development, offering a therapeutically effective and clinically translatable strategy for UC management.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2020
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IF 5.162
Peiyun Li,Qianqian Zhou,Yuanming Chu,Weiqing Lan,Jun Mei,Jing Xie
The present study evaluated the effects of chitosan (CH) and sodium alginate (SA) bioactive coatings containing 0.1, 0.2 and 0.3% ε-polylysine (ε-PL) combined with high CO 2 modified atmosphere packaging conditions (MAP, 60% CO 2 /5% O 2 /35% N 2 ) on the quality of cultured pufferfish ( Takifugu obscurus ) at 4 °C for 18 days. Results showed that CH-SA coatings containing ε-PL and high CO 2 MAP treatments could significantly lower total viable count (TVC), Pseudomonas spp., H 2 S-producing bacteria and lactic acid bacteria counts (LAB), and reduce the productions of off-flavor compounds including total volatile basic nitrogen (TVB-N), trimethylamine (TMA) and ATP-related compounds. Volatile compounds were identified and quantified by SPME gas chromatography–mass spectrometer (SPME-GC/MS) for pufferfish during cold storage and the bioactive coating treated pufferfish significantly lowered the relative content of fishy flavor compounds, such as 1-octen-3-ol, hexanal, (E)-2-octenal, octanal and 2,3-butanedione. Further, CH-SA coatings containing ε-PL and high CO 2 MAP treatments could more efficiently retard the water migration by magnetic resonance imaging (MRI) results, and maintained the quality of pufferfish during storage at 4 °C according to organoleptic evaluation results.
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JOURNAL OF COLLOID AND INTERFACE SCIENCE
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2019
·
IF 6.361
Lihong Fan,Yuqing Lu,Li-Ye Yang,Fangfang Huang,Xiao-kun Ouyang
Hypothesis We synthesized composite microspheres from cellulose nanocrystal (CNC), polyvinyl alcohol (PVA), and sodium alginate (SA), which were modified with polyethyleneimine (PEI) to introduce a high density of active amino sites onto the surface via the Schiff base reaction. We hypothesized that these (SA/CNC/PVA)@PEI microspheres would have a high adsorption capacity for aqueous diclofenac sodium (DS). Experiments The PEI-modified composite microspheres were characterized and assessed and optimized for aqueous DS adsorption. In addition, the morphology and synthesis mechanism of the adsorbent were studied. Findings The adsorption process showed a good fit with the pseudo-second-order kinetic model (i.e., the process is driven by a chemical adsorption mechanism) and Langmuir adsorption isotherm model (i.e., adsorption follows a single-layer process). Under the optimum experimental conditions (pH: 4.5, adsorption time: 50 min, temperature: 303 K), the maximum adsorption capacity was 418.4104 mg/g, which was relatively high compared to other reported adsorbents. Importantly, after five adsorption–desorption cycles, (SA/CNC/PVA)@PEI showed only a slight loss in adsorption capacity. Compared with other reported adsorbents, the core–shell composite has a good DS adsorptive capacity and high recyclability.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2026
·
IF 8.5
Chen Chen,Wenhui Li,Huiying Tian,Xiaoyu Fan,Songtao Wang,Shuo Zhao,Liangmin Yu
To produce efficient green adsorbent materials, neodymium alginate (SA/Nd) gel spheres were prepared by crosslinking sodium alginate with rare earth ions using the droplet polymerization method. The prepared materials were characterized and analysed by SEM–EDS, XRD, TGA, FT–IR, UV–Vis, BET–BJH and XPS, and the adsorption performance of the SA/Nd for two azo dyes in water was investigated. The results show that the SA/Nd has a pleated structure with abundant oxygen-containing functional groups. The maximum adsorption capacities for the dyes reached 1325 and 1175 mg/g under the optimal conditions. The adsorption process is consistent with the pseudo-second-order kinetic model and is accomplished by a combination of physical and chemical adsorption. The Langmuir isotherm model better reflects the adsorption equilibrium, and surface monolayer-dominated adsorption occurs. After seven cycles of desorption and recycling of the adsorbent material, the removal rate of the two azo dyes remained above 80%. The SA/Nd promotes the efficient adsorption of dyes mainly through electrostatic interactions, hydrogen bonding and complexation. These results provide reference data for the treatment of printing and dyeing wastewater.
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CHEMICAL ENGINEERING JOURNAL
·
2023
·
IF 15.1
Shi Li,Zhihao Zheng,Sijie Xia,Jiwen Hu,Lihui Chen,Liulian Huang,Qingping Song,Xianrong Shen,Wei Zhang
The cross-linking coating modification strategy was adopted to construct an environmentally sustainable bamboo cellulose-based composite nanofiltration membrane (CL-NF-BCM), with bamboo cellulose providing as the support material. Solid-state Nuclear Magnetic Resonance ( 13 C NMR) results show that alginate (ALG) and carboxymethyl cellulose (CMC) were successfully cross-linked onto the cellulose membrane. Furthermore, the transfer of chemical elements was confirmed by X-ray Photoelectron Spectroscopy (XPS) measurements. The microscopic morphology illustrates that after cross-linking coating modification, the surface of the bamboo cellulose membrane turns from a uniform porous structure to a polymerized layer with interwoven network structure. In addition, the result of Brunauer-Emmett-Teller (BET) shows that the average pore size of the as-prepared CL-NF-BCM of about 1.1 nm. The performance testing results show that the CL-NF-BCM cellulose membrane had a rejection of 48% against 500 ppm NaCl solution and membrane flux of 17 L·m −2 ·h −1 under a nanofiltration condition of 0.5 MPa operating pressure. This work enriches a high value-added application of bamboo products, as well as provides a novel perspective for membrane surface modification.
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International Journal of Electrochemical Science
·
2023
·Vol. 12
·期 12
·11633-11645
·
IF 1.5
Xiuqiong Chen,Meixi Feng,Huiqiong Yan,Wei Sun,Zaifeng Shi,Qiang Lin
To achieve the accurate determination of trichloroacetic acid (TCA) in water chlorination, the sensitive electrochemical biosensor, Nafion/myoglobin-sodium alginate-graphene composite modified carbon ionic liquid electrode (Nafion/Mb-SA-GR/CILE), was fabricated by the electrodeposition method. Spectroscopic results implied that Mb could keep its biological activity in the SA-GR composite film. Direct electrochemistry of Nafion/Mb-SA-GR/CILE indicated that direct electron transfer of Mb was realized on the modified electrode, which was attributed to the synergistic effects of SA-GR composite film with excellent electrocatalytic capability and good biocompatibility. Furthermore, the modified electrode displayed good electrocatalytic ability towards TCA with the linear range from 7.5 to 69.0 mmol/L and a low detection limit of 0.163 mmol/L (3σ). Meanwhile, the modified electrode possessed good stability, reproducibility and excellent accuracy for the detection of tap-water, exhibiting great potentials for electroanalysis and electrocatalysis applications.
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