Nature Communications
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2026
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IF 18.1
Zhang Keming,Huan Haishan,Tian Xiaohe,Yin Chongshan,Ma Xiaohua,Wang Shaofei
Helium (He) recovery via conventional cryogenic distillation is highly energy-intensive and costly. Membrane separation features modularity and efficiency, but mixed-matrix membranes (MMMs) often suffer from discontinuous channels and poor filler–polymer compatibility, which impair separation performance. Here, we report an MMM platform by embedding a continuous 3D nanoporous ZIF-67-NH 2 gel within a polyimide matrix. The gel functions as a dual-functional crosslinker, forming covalent amide linkages and hydrogen bonds with the polymer to eliminate interfacial voids, while creating interconnected, selective nanochannels through its intrinsic nanoporosity. This yields He/CH 4 performance: 549 Barrer He permeability and 110.3 selectivity, surpassing the benchmark membranes. The membrane retains over 95% performance in mixed-gas tests over 180 h. Process simulations show that a hybrid membrane–cryogenic system achieves >93% He recovery and 74% energy savings. This work provides an energy-efficient platform for critical gas separations.
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JOURNAL OF NANOBIOTECHNOLOGY
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2026
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IF 15
Wang Huan-Hui,Nan Long-Yi,Zheng Yan,Guo Jianpeng
Sonodynamic therapy (SDT) offers deep tissue penetration and noninvasive tumor treatment, yet its efficacy remains limited by inadequate reactive oxygen species (ROS) generation and an immunosuppressive tumor microenvironment (TME). In this work, we developed a porphyrin-based bimetallic nanoplatform by integrating Fe and Mn centers within a structurally ordered metal-organic framework (MOF), followed by surface modification with the tumor-homing peptide CRGDK to achieve active targeting. The rationally engineered Mn-Fe(TCPP) MOF exhibits a spatially confined configuration that minimizes π-π aggregation of porphyrins enhancing ROS production under ultrasound (US). Meanwhile, Fe 3+ and Mn 2+ are released in the mildly acidic TME. The Fe 3+ catalyzes Fenton-like reactions to generate abundant •OH radicals, leading to glutathione (GSH) depletion, glutathione peroxidase-4 (GPX4) inhibition, and triggers ferroptosis. Simultaneously, Mn 2+ and ROS inflict mitochondrial damage and cause cytosolic double-stranded DNA (dsDNA) leakage, thereby activating the cGAS-STING signaling pathway and amplifying type I interferon (IFN-I) responses. This dual immunometabolic modulation induces immunogenic cell death (ICD), promotes dendritic cells (DCs) maturation, and strengthens adaptive antitumor immunity. Overall, this study presents a concise strategy coupling ferroptosis induction with innate-immune activation through a porphyrinic bimetallic MOF, offering a promising direction for SDT-based immunotherapy against hard-to-treat tumors. Graphical The alternative text for this image may have been generated using AI.
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Journal of Water Process Engineering
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2026
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IF 6.6
Suyu Xu,Liulu Liu,Fuwen Lei,Gexin Liu,Liang Xiao,Yafeng Zhang,Guangli Li
A sensitive voltammetric platform for determination of pefloxacin. • UiO-67/MWCNT-COOH exhibited significant synergistic effect toward pefloxacin. • Wide linear range (0.01–10 μM), low LOD (5.0 nM) and good stability (30 days). • High sensitivity in the detection of pefloxacin in lake water and honey. Developing a simple and efficient detection method for pefloxacin (PEF) is crucial for environmental monitoring and food safety assurance. In this study, we designed a novel electrochemical sensor for PEF detection by integrating zirconium-based metal-organic frameworks (UiO-67 MOFs) with carboxylated multi-walled carbon nanotubes (MWCNT-COOH) through a two-step hydrothermal and ultrasonic-assisted strategy. The coordination of the carboxyl groups of MWCNT-COOH with the unsaturated metal sites on the zirconium clusters of UiO-67, and the strong electrostatic attraction between PEF and the negatively charged composite surface, as well as strong π-π stacking interactions between the aromatic ring of PEF and the benzene rings of the organic ligands in UiO-67 and the graphite surface of MWCNT-COOH, collectively contribute to the efficient accumulation and sensitive detection of PEF. The sensor demonstrated a wide linear range (0.01–10 μM), an ultralow detection limit (0.005 μM), and outstanding overall sensing performance. When applied to real-world samples, including lake water and honey, the method achieved satisfactory recovery (94.48% − 108.9% and 100.9% to 106.4%, respectively), confirming its practical applicability for monitoring PEF in environmental and food matrices. A sensitive electrochemical sensing platform was developed for the detection of trace pefloxacin residues in lake water and honey by integrating zirconium-based metal-organic frameworks (UiO-67 MOFs) with carboxylated multi-walled carbon nanotubes (MWCNTs-COOH). Download: Download high-res image (126KB) Download: Download full-size image
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ACS Sensors
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2026
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IF 10.9
Yali Zhao,Shiqi Sun,Ezgi Pulatsu,Kai Wen Choo,Yunfei Xie,Zhilong Yu
Real-time and accurate monitoring of meat freshness remains a critical challenge for intelligent food-sensing systems. Herein, a dual-mode sensor array was developed by combining ratiometric fluorescent lanthanide metal−organic frameworks (Ln-MOFs) with pH-responsive anthocyanins for real-time, high-precision monitoring of pork freshness. Specifically, two “traffic-light” ratiometric fluorescent probes were engineered by doping Eu3+ and Tb3+ into UiO-66-OH. These probes exhibited exceptional sensitivity and specificity toward ammonia and biogenic amines, achieving detection limits for ammonia as low as 1.224 ppm (Eu3+-doped) and 2.359 ppm (Tb3+-doped). Furthermore, the dual-mode array demonstrated robust fluorescence-colorimetric responses and outstanding color stability (Euclidean distance <5 after 14 days of storage). During pork freshness monitoring, fluorescence signals enabled sensitive early-spoilage warnings at TVB-N levels of 15–20 mg/100 g (less fresh state), while colorimetric signals provided visual cues for naked-eye discrimination, changing from pink to purple and then to blue. By coupling the array with three convolutional neural networks, high-accuracy classification of pork into fresh, less fresh, and spoiled states was achieved, reaching a maximum accuracy of 97.8%. This strategy provides a reliable and early-warning-capable solution for real-time pork freshness monitoring in intelligent food packaging and logistics.
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ANALYTICAL CHEMISTRY
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2026
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IF 7.3
Yi-Xuan Li,Yu-Xuan Dai,Yuechao Wu,Haoming Ren,Jérome Chauvin,Xue-Ji Zhang,Serge Cosnier,Dan Shan
Electrochemiluminescent (ECL) biosensing is fundamentally limited by inefficient coupling between catalytic radical generation and luminophore excitation. Here, we report an amino acid-programmed biomineralization strategy for constructing radical-proximal enzyme–MOF interfaces under mild aqueous conditions. Serine reconfigures zirconium precursor chemistry to convert a charge-mismatched mineralization process into a charge-adaptive one, enabling biomineralization of cationic horseradish peroxidase (HRP) within PCN-224. The resulting HRP@PCN-224(Ser) exhibits enhanced enzyme loading, preserved protein structure, improved catalytic competence, and pronounced solvent tolerance. Mechanistic analyses indicate that serine-mediated mineralization does more than facilitate enzyme incorporation: it creates a spatially integrated microenvironment in which H2O2 activation and ZnTCPP excitation are more effectively coupled, leading to enhanced ECL transduction. Accordingly, HRP@PCN-224(Ser) produces an approximately 9-fold stronger ECL response than the serine-free counterpart in the presence of H2O2. Integrated with a dual-aptamer signal-off format, this interface enables ECL sensing of influenza H1N1 hemagglutinin (HA) over 0.1–1000 ng mL–1 with a detection limit of 0.03 ng mL–1, together with good selectivity and satisfactory recovery in serum samples. These findings establish amino acid programmed biomineralization as an interfacial design strategy for enzyme–MOF integration and provide a mechanistically grounded framework for improving ECL bioanalysis through radical-proximal transduction.
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Journal of Materials Chemistry A
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2026
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IF 9.2
Yixuan Gao,Ziyi Tang,Huanhui Zhang,Kai Zhang,Wenming Sun,Yueyue Wang,Hongliang Dong,Sihui Zhan,Yang Tian
Water splitting via photoelectrochemical (PEC) system is a promising approach for sustainable hydrogen production. Yet, photogenerated charge accumulation and recombination impede it by water oxidation kinetics due to not only four-electron transfer process but also the oxygen spin state change. Here, a modulation of spin state in NiFe-based metal-organic framework (NiFe-MOF) cocatalyst is employed on BiVO4 photoanodes to accelerate interface kinetics. X-ray magnetic circular dichroism combined with spin-polarized density functional theory calculations reveal that Fe incorporation induces a spin-state transition of the Ni dz2 orbital (dz2↓ to dz2↑) through asymmetric Fe-O-Ni bond coupling within the MOF nodes. The resulting downward shift of the Ni dz2 energy level weakens the adsorption of oxygenated intermediates (*OH/*OOH) on Ni sites, thereby facilitating *OOH desorption and O2 release during oxygen evolution. Consequently, the NiFe-MOF/BiVO4 photoanodes exhibit a significantly enhanced PEC performance, delivering a photocurrent density of 6.0 mA cm-2 at 1.23 V versus Reversible Hydrogen Electrode (RHE) under simulated sunlight. This work highlights asymmetric metal–oxygen bond-driven electron spin engineering as an effective strategy to boost PEC activity.
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JOURNAL OF ALLOYS AND COMPOUNDS
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2026
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IF 6.7
Yuyang Zhang,Zixuan Chen,Yuqing Zhang,Qiong Wu,Yipu Wang,Jiaying Dong,Zihan Yuan,Jingyun Liang,Yang Wu,Zhengbo Han
The application of Pickering emulsions in interfacial catalysis provides a promising platform for biphasic reactions. Metal–organic frameworks (MOFs), owing to their high surface area, tunable porosity, and flexible functionalization, have emerged as ideal stabilizers for Pickering emulsions in such catalytic systems. Herein, we report the incorporation of PdNi alloy nanoparticles into MIL-101, where the Lewis acidity of the MOF combined with the catalytic activity of PdNi NPs enables two-step one-pot reactions. Interestingly, the resulting bimetallic PdNi@MIL-101 not only acts as an effective emulsifier to stabilize Pickering emulsions, but also exhibits superior performance in the reductive amination of Nitroarenes compared with the corresponding monometallic@MOFs. Moreover, PdNi@MIL-101 demonstrates excellent stability, maintaining high reproducibility after five consecutive cycles. This work not only reduces the catalyst cost, but also exploits the synergistic effect of bimetallic components and interfacial catalysis, which opens up new avenues for efficient and environmentally friendly organic synthesis.
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POLYMER ENGINEERING AND SCIENCE
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2026
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IF 3.6
Hafiza Aroosa Aslam Khan,Naveed Ramzan,Asif Jamil,Ghulam Rasool,Muneerah Alomar,Muhammad Sarfraz
Decarbonization is essential to address climatic variations caused by greenhouse effects. Membrane-based separation processes present an energy-efficient and scalable pathway for flue gas purification. Permeability-selectivity trade-off of polymeric membranes can be mitigated through combined impregnation of bi-fillers within polymer matrix coupled with applying ultrathin secondary polymer coating to fabricate efficacious dual-layer composite membrane. Microporous activated MOF-5 nanocrystals with high surface area and CO 2 affinity, combined with graphene nanoplatelets possessing exceptional CO 2 uptake, were synergistically embedded into flexible polysulfone matrix. Biodegradable poly(vinyl alcohol) coating layer was uniformly deposited onto doped polysulfone substrate, yielding novel class of anisotropic dual-layer mixed matrix composite membranes, rendering drastically improved CO 2 /N 2 selectivity of 70 and upgraded CO 2 permeability of 92 Barrer as compared to bare polysulfone membrane. Advanced characterizations verified uniform nanofiller dispersion, strong interfacial bonding, and enhanced thermal stability. Five percent PVA coating boosted thermal stability and improved mechanical robustness by 84%, markedly strengthening membrane structural and thermal resilience. An effective strategy is introduced to produce dual-layer membranes with remarkable CO 2 capture performance via optimized bi-filler loading and PVA based surface modification. Highlights Solvothermal synthesis of highly microporous activated MOF-5 nanocrystals. Preparation of Zn-BDC MOF- and graphene nanoplates-embedded composite membranes. Enhanced nanofiller-polymer interfacial compatibility furnishing uniform filler dispersal. Constructing a dual-layer composite membrane by depositing an ultrathin poly(vinyl alcohol) layer. Marked improvement in decarbonization performance of prepared multilayered membranes.
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CHEMICAL ENGINEERING JOURNAL
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2026
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IF 12.5
Duo Zhang,Ying-Nan Dou,Rui Gao,Xian-Fa Zhang,Hui Zhao,Xiao-Li Cheng,Shan Gao,Ying-Ming Xu,Li-Hua Huo
Rapid, highly sensitive detection of mustard gas is a critical requirement in public safety and national defense. However, achieving highly sensitive, ppb-level detection of mustard gas under low-power conditions remains a significant challenge. Focusing on the typical blister agent simulant 2-chloroethyl ethyl sulfide (2-CEES), a solvothermal method was employed combined with controlled thermal treatment to fabricate an ultrathin porous NiFe 2 O 4 /NiO nanosheets heterostructure sensor derived from an Fe-Ni-MOF in-situ grown on a ceramic tube in this study. This material possesses uniformly distributed intimate heterogeneous interface, a high specific surface area (95.8 m 2 ·g −1 ), and abundant surface active sites, thereby significantly enhancing its adsorption and catalytic oxidation capability toward 2-CEES. At a low operating temperature of 130 °C, the sensor demonstrates a high response of 41.5 toward 10 ppm 2-CEES, a rapid recovery capability of only 84 s, and a low detection limit of 20 ppb, along with excellent selectivity, humidity resistance, reproducibility, and long-term stability. Through systematic characterization including XPS, in-situ DRIFTS, TPD, and DFT calculations, the multi-step catalytic oxidation pathway of 2-CEES on the composite surface is elucidated, along with the mechanism by which the heterostructure enhances gas-sensing performance via band structure modulation, interfacial charge transfer, and the built-in electric field. This study offers both new materials and novel insights for the development of low-power, highly sensitive sensors for trace detection of chemical warfare agents.
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JOURNAL OF MEMBRANE SCIENCE
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2026
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IF 8.8
Lingya Fei,Xiaoting Ye,Jingyu Yu,Baoliang Chen,Xiaoying Zhu
Metal–organic frameworks (MOFs), with ultrahigh surface areas and tunable pore architectures, are promising for advanced separation membranes; however, despite advances in defect engineering for catalysis and adsorption, its potential in membrane separations remains largely unexplored. Here, we introduce a defect engineering strategy for the Zr-MOF MIP-202(Zr) through precise regulation of defect density. The defective MIP-202(Zr) was integrated with graphene oxide (GO) nanosheets via vacuum-assisted self-assembly to form hierarchical composite membranes. Notably, the defective composite membrane exhibited a two-fold increase in water permeability (up to 36.74 L m −2 h −1 bar −1 ) compared to the defect-free counterpart, while maintaining high rejection (>95%) for multiple model dyes, overcoming the conventional permeability–selectivity trade-off. The introduced defects created open sites and enhanced mass transport, collectively improving membrane hydrophilicity and water permeability. This work demonstrates defect engineering as a transformative strategy for designing high-efficiency MOF-based membranes, with significant implications for sustainable wastewater treatment and resource recovery.
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APPLIED SURFACE SCIENCE
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2026
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IF 6.6
Xiaojing Liu,Fozia Sultana,Ting Xiao,Qiurong Wang,Meijie Shi,Xiaoqing Yan,Tongtong Li,Renhong Li
High-entropy alloy (HEA) catalysts derived from metal-organic frameworks (MOFs) pave the way for efficient electrochemical energy conversion. Herein, we report the synthesis of C@FeCoNiMnMo/NF, C@FeCoNi/NF and C@FeCoNiMn/NF catalysts via a one-step hydrothermal process coupled with subsequent calcination. Structural and morphological characterizations (XRD, XPS, SEM, and TEM) verifies the successful formation of a carbonized MOF-derived high-entropy alloy with uniform metal dispersion. Among these catalysts, C@FeCoNiMnMo/NF exhibits superior urea oxidation reaction (UOR) activity, achieving E 10 = 1.24 V and E 100 = 1.32 V (corresponding to 10 and 100 mA·cm −2 , respectively), with excellent durability over 30 h of continuous operation. The enhanced adsorption of key intermediates induced by Mo doping, as evidenced by both electrochemical analysis and DFT calculations, is identified as the primary factor responsible for the accelerated UOR kinetics. This work establishes an innovative approach for the rational design of MOF-derived HEA catalysts, which boosts the efficiency of urea-assisted hydrogen production from water.
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JOURNAL OF ALLOYS AND COMPOUNDS
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2026
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IF 6.7
Jinyi Hu,Hongtao Zhou,Siyan Lv,Jiaming Wu,Baochen Tian,Yuehong Zhang,Caisheng Li,Zhihuan Zheng,Zejie Zhang,Xinjun Bao
Developing cost-effective bifunctional oxygen catalysts with robust activity and stability remains a core challenge for rechargeable zinc-air batteries (ZABs), primarily hindered by the slow kinetics of oxygen reduction/evolution reactions (ORR/OER). Herein, we report a Fe/Co-based composite catalyst, P-Fe-ZIF67@PI-COF-T (T represents calcination temperature), which is constructed by using a polyimide-based covalent organic framework as a support, followed by phosphorization and high-temperature pyrolysis of ZIF67 (zeolitic imidazolate framework67). Electrochemical measurements demonstrate outstanding bifunctional performance: an ORR half-wave potential (E 1/2 ) of 0.81 V, an OER overpotential of 250 mV at 10 mA cm −2 , and a ΔE of 0.67 V. The corresponding ZABs exhibit a high peak power density of 142.8 mW cm −2 and long-term durability for 300 h. Systematic analysis attributes the excellent performance to the synergistic effects of N/P co-doping induced defects, and the graphitized carbon layer. This study provides a rational design principle for advanced non-noble metal catalysts.
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