RSC Advances
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2022
·Vol. 12
·期 18
·11090-11099
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IF 4.036
Jiacheng Shi,Rui Shu,Xiuyuan Shi,Yunfei Li,Jiangge Li,Yi Deng,Weizhong Yang
Drug-free antibacterial strategies are of great significance for pathogenic bacterial infection treatment in clinical practice. Phototherapy with antibacterial function plays a vital role in mainstream germicidal research. However, phototherapy could lead to residual heat and excess reactive oxygen species (ROS), which are the main side-effects during antibacterial treatment. Unique CoFe2O4/MXene (CM) nanoenzymes, which were fabricated with electrostatic interactions, have been designed to conquer those challenges caused by side-effects of phototherapy in our research. The CM nanoenzymes possess many promising properties including photothermal and photodynamic induced phototherapy and mimic peroxidase (POD), glutathione oxidase (GSHOx), and catalase (CAT). Upon treatment with near-infrared (NIR) light, CM nanoenzymes can create a local high-temperature circumstance as well as raise bacterial membrane permeability. Furthermore, the photodynamic process and multi-enzyme-mimicking activities of CM enzymes boost the interbacterial ROS level. Herein, bacteria can hardly survive in synergistic phototherapy and multi-enzyme-mimicking catalytic therapy in vitro and in vivo. Meanwhile, the CM nanoenzymes exhibit excellent biocompatibility in vitro and in vivo. Overall, this research establishes a strong foundation for effectively employing nanoenzymes, leading to a new way to cure bacterial infections.
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ANALYTICAL AND BIOANALYTICAL CHEMISTRY
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2022
·Vol. 414
·期 7
·2355-2362
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IF 4.478
Zhao Xueqi,Zhang Yue,Wang Xinghua,Ma Pinyi,Song Daqian,Sun Ying
Long-range surface plasmon resonance (LRSPR) has demonstrated excellent performance in sensing and detection, due to its higher accuracy and sensitivity compared with conventional surface plasmon resonance (cSPR). In this work, we establish an LRSPR biosensor which employs PDA/Ti 3 C 2 -MXene/PDA-gold film as a sensing substrate and gold nanoparticles (AuNPs) as enhancers. Ti 3 C 2 -MXene is an emerging two-dimensional (2D) layered material which is used extensively in immunoassay and biosensing. The sensing substrate comprises two polydopamine (PDA) films between which is sandwiched a Ti 3 C 2 -MXene film based on a gold film, which provides a large surface area and abundant binding sites to rabbit anti-human IgG (Ab 1 ). Sandwich amplification is adopted to enhance the sensitivity of the LRSPR biosensor, and AuNPs/staphylococcal protein A (SPA)/mouse anti-human IgG (Ab 2 ) composites are introduced into the flow cell as enhancers after the immune binding of human IgG to Ab 1 . The antigen (human IgG) detection range is 0.075 μg mL −1 to 40 μg mL −1 , and the limit of detection is almost 20 times lower than that for cSPR biosensors. This novel LRSPR biosensor demonstrates excellent performance in immune sensing over a broad detection range and a low limit of detection. Subsequent modification of the LRSPR sensing platform could be made for extensive application in various biological detection fields. Graphical abstract
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COLLOIDS AND SURFACES B-BIOINTERFACES
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2022
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IF 5.999
Miao Qin,Wenfeng Yuan,Xiumei Zhang,Yizhu Cheng,Mengjie Xu,Yan Wei,Weiyi Chen,Di Huang
Conductive hydrogels based on MXene have gained more attention due to the excellent conductive property and biocompatibility. At present, they have great potential in electronic skins, personally healthcare monitoring and human motion sensing. However, MXene are prone to be oxidized due to the abundant hydroxyls , which results in the unstable conductive property of hydrogel. To improve the shortcoming, conductive PAA/PAM/MXene/TA hydrogel was prepared, in which the introduction of TA can prevent MXene from oxidation owing to the great deal of pyrogallol groups. Mechanical tests showed that the tensile strength , toughness and elongation at break of PAA/PAM/MXene/TA hydrogel are 0.251 ± 0.05 MPa, 0.895 ± 0.16 MJ/m 3 and 560.82 ± 19.56%, respectively, indicating the hydrogel possess good stretchability. In addition, the MXene and TA were introduced into hydrogel through hydrogen bonds , which endow the hydrogel with good restorability and self-healing property. Resistance variation-strain curves demonstrated that the introduction of MXene endue the hydrogel with appreciable sensing performances. Moreover, in vitro cytotoxicity assay indicated that the hydrogel has good biocompatibility. In conclusion, PAA/PAM/MXene/TA hydrogel has great potential in flexible wearable sensor field.
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Membranes
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2022
·Vol. 12
·期 4
·368
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IF 4.562
Yi Wang,Yuqi Nie,Chunhong Chen,Hongjie Zhao,Ye Zhao,Yujin Jia,Jun Li,Zhanguo Li
MXene nano-sheets were introduced into a thin-film composite membrane (TFC) to reduce the mass transfer resistance (concentration polarization) and improve the membrane performance. The process entailed dissolving the MXene nano-sheets in a membrane casting solution using the blending method and introducing them into the porous support layer to prepare a modified thin-film composite forward osmosis (TFC-FO) membrane. The results showed that the water contact angle decreased by about 16%, indicating that the hydrophilicity was strengthened, and the O/N ratio of the active selective layer decreased by 13%, indicating an increased degree of crosslinking, thereby demonstrating that the introduction of MXene nano-sheets changed the properties of the membrane and played a positive role in its physicochemical properties. In contrast to the unmodified TFC-FO membrane, the modified membrane had a slightly higher reverse solute flux, while its water flux increased by about 80%. Its specific reverse osmosis flux was also significantly optimized (only 0.63 g/L). In conclusion, adding MXene nanosheets to TFC-FO membranes led to the modified membranes with better mass transfer, lessened internal concentration polarization (ICP), and better osmotic separation.Keywords:TFC-FO membrane;MXene nano-sheets;internal concentration polarization
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ANALYTICA CHIMICA ACTA
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2022
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IF 6.911
Rui Zhou,Bo Tu,Dacheng Xia,Hanping He,Zhiwei Cai,Nan Gao,Gang Chang,Yunbin He
Accurate measurement of dopamine (DA) is of great significance for human health monitoring and disease prevention. Herein, two-dimensional Ti 3 C 2 T x MXene with high performance was prepared by layer liquid exfoliation method and used for the modification of gate electrode. The glassy carbon electrode (GCE) modified with Pt/Ti 3 C 2 T x was used as the gate, and assembled with monolayer graphene channel to form a complete transistor device. The device combines the amplification effect of transistors, good electrical conductivity of Ti 3 C 2 T x MXene and excellent catalytic properties of Pt nanoparticles , showing a low detection limit (50 nM) and a wide detection concentration range (50 nM-9 mM) of DA. Ti 3 C 2 T x MXene not only provides a large number of attachment sites for the deposition of Pt nanoparticles , but also improves the electrical conductivity and hydrophilicity of the electrode material , thus enhancing the sensitivity of the device and facilitating the penetration of the solution to be measured. In addition, Ti 3 C 2 T x MXene is negatively charged, it has a certain electrostatic adsorption effect on protonated DA and electrostatic repulsion effect on negatively charged interfering substances. As a result, the device exhibits good selectivity , which provides a great application prospect for the construction of DA sensing platform.
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Electrocatalysis
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2022
·Vol. 13
·期 4
·469-478
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IF 2.933
Guo Shanshan,Jian Xuan,Hou Xiaodong,Wu Jianhong,Tian Bining,Tian Yue
Developing electrocatalysts with ultralow platinum (Pt) content for hydrogen evolution reaction (HER) is essential. In this work, we electrodeposited Pt nanoparticles on the composite carrier of polypyrrole (PPy) nanowires and MXene materials, thereby obtaining a catalyst with a mixed structure consisting of three materials with different dimensions, namely zero-dimensional (0D) platinum nanoparticles (Pt NPs ), one-dimensional (1D) PPy nanowires and two-dimensional (2D) MXene nanosheets. The PPy nanowires were compounded with MXene nanosheets, which enhanced the conductivity of the catalytic carrier and provided more active sites. The overpotential of the electrocatalyst with ultralow Pt loading (17.11 μg cm ‒2 ) is 40 mV when the current density is 10 mA cm −2 , which is very close to the commercial 20 wt% Pt/C (41 mV). The catalyst exhibits high turnover frequencies (2.21 H 2 s −1 in 0.5 M H 2 SO 4 ) at 100 mV and has relatively good stability due to the composite structural characteristics of 1D and 2D materials. This research provides a direction for the design and development of other MXene-based electrocatalysts and more conductive polymers.
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JOURNAL OF COLLOID AND INTERFACE SCIENCE
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2022
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IF 9.965
Yujie Gao,Yuanhao Dong,Shuting Yang,Anchun Mo,Xin Zeng,Qianming Chen,Qiang Peng
Developing antibiotics-independent antibacterial materials is of great importance for combating drug-resistant bacteria, such as methicillin-resistant Staphylococcus aureus (MRSA). MXene (transition metal carbides and nitrides), a class of novel 2D nanomaterials , has shown great potentials in biomedical areas. However, the effect of MXene size on its properties and bioactivity is still unknown. Herein, we report for the first time that the antibacterial photothermal therapy efficacy of Ti 3 C 2 T x MXene nanosheets is size-dependent. Three MXene suspensions with small size of 196 nm (MX-s), medium size of 347 nm (MX-m) and large size of 497 nm (MX-l) were prepared via ultrasonication. Upon NIR irradiation for 5 min, the temperature of MXene suspensions (10 μg/mL) increased to 64, 60 and 56 °C for MX-s, MX-m and MX-l, respectively. Accordingly, the viability loss of MRSA induced by MX-s, MX-m and MX-l under NIR was 93%, 69% and 56%, respectively. The in vivo study in the MRSA-infected mouse model showed that the photothermal therapy efficacy of MX-s was comparable to that of the positive control vancomycin . This is the first report on the size-dependent photothermal effect and photothermal antibacterial activity of MXene, which may guide the development of MXene-based therapeutics in the future. In addition, the drug-free antibacterial therapy has great implications for the treatment of antibiotics-resistant bacteria infections.
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JOURNAL OF BIOMATERIALS APPLICATIONS
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2022
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IF 2.712
Lumin Li,Xiaofeng Ji,Kai Chen
The rapid development of flexible electronic technology has led to the in-depth study of flexible wearable sensors to achieve accurate sensing under different external stimuli. However, it is still a huge challenge to develop hydrogel-based wearable skin-like sensors with super ductility, high sensitivity, and self-healing properties. Herein, the Ti3C2 type of MXene was synthesized, and the Ag/MXene nanocomplexes were incorporated into polyvinyl alcohol-borax matrix to construct a novel composite hydrogel as the multifunctional nanofillers, which could bring both improved properties and novel functionalities. The Ag/MXene-Poly (vinyl alcohol) (PVA) hydrogel displayed integrated merits of highly strain sensitive (GF = 3.26), self-healing (within 10 min, 91% healing efficiency), and excellent antibacterial activity. The hydrogel could be assembled into a wearable skin-like sensor to monitor human movement, including large deformations (finger, elbow, wrist, and knee bending) and tiny deformations (mouth’s movement and throat vocalization) in real time. Therefore, this work shed a new light on the development of flexible wearable skin-like sensors for the personalized healthcare monitoring, human–machine interfaces, and artificial intelligence.
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ACS Nano
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2022
·
IF 18.027
Zhiming Deng,Lulu Li,Pingping Tang,Chenyang Jiao,Zhong-Zhen Yu,Chong Min Koo,Hao-Bin Zhang
Two-dimensional transition metal carbide/nitride (MXene) conductive inks are promising for scalable production of printable electronics, electromagnetic devices, and multifunctional coatings. However, the susceptible oxidation and poor rheological property seriously impede the printability of MXene inks and the exploration of functional devices. Here, we proposed a controllable surface grafting strategy for MXene flakes (p-MXene) with prepolymerized polydopamine macromolecules to protect against water and oxygen, enrich surface chemistry, and significantly optimize the rheological properties of the inks. The obtained p-MXene inks can adapt to screen-printing and other high-viscosity processing techniques, facilitating the development of patterned electromagnetic films and coatings. Interestingly, the printed MXene polarizer can freely switch and quantitatively control microwave transmission, giving an inspiring means for smart microwave modulation beyond the commonly reported shielding function. Moreover, the introduction of polydopamine nanoshell enables the infrared emissivity of MXene coating to be adjusted to a large extent, which can produce infrared anti-counterfeiting patterns in a thermal imager. Therefore, multifunctional antioxidant p-MXene inks will greatly extend the potential applications for the next-generation printable electronics and devices.
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JOURNAL OF COLLOID AND INTERFACE SCIENCE
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2022
·
IF 9.965
An Gui,Xiuyu Chen,Xiaoyu Zhang,Changchang Shi,Haibo Yi,Yongan Hu,Wei Zeng,Siliang Wang,Limin Ruan,Yi Xiong,Zhiliang Chen
With WO 3 /BiVO 4 /MXene ternary composite layers as a working electrode, a smart volumetric photoelectrochemical system using electrostatic bias voltage inducted by atmospheric electric field was developed. Under single sun illumination and 0.8 V hardwired bias, the current response of the ternary electrode is 1.15 mA cm −2 , which is 1.31 times higher than that of the WO 3 /BiVO 4 electrode, mainly due to the higher charge transfer rate between the MXene layer and the BiVO 4 structure. Further, the response of the ternary electrode increases to 1.39 mA cm −2 at an extra atmospheric electric field of 1100 V m −1 . It can be demonstrated that the effect of the atmospheric electric field can be regarded as an extra hardwired bias of 0.101 V in the system. The experimental results reveal that the native carriers, including inducted electron/holes in MXene and BiVO 4 , and carriers in the electrolyte, are all effectively excited by the electrostatic induction of atmospheric electric field.
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Materials Today Energy
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2022
·
IF 9.257
Hong Zhang,Yao Chen,Xiaofang Liu,Hengyang Wang,Chengzhi Niu,Sikang Zheng,Bin Zhang,Xu Lu,Guoyu Wang,Guang Han,Xiaoyuan Zhou
SnSe-based materials, comprising nontoxic, eco-friendly and abundant elements, have intrinsically low lattice thermal conductivity , which are promising candidates for thermoelectric conversion. However, unmodified, polycrystalline SnSe reveals poor electrical transport properties due to the lower carrier mobility . Herein, two-dimensional Ti 3 C 2 T x MXene has been incorporated into SnSe matrix by solution synthesis and fast consolidation, which efficiently increases the carrier mobility and concentration; accordingly, the electrical conductivity is improved in the temperature range of 323–523 K. Meanwhile, SnSe/Ti 3 C 2 T x composites achieve diminished lattice thermal conductivity, delivering a low value of 0.41 W m −1 K −1 at 773 K. Ultimately, a peak zT of 0.93 at 773 K is attained in SnSe/Ti 3 C 2 T x composite with addition of 0.3 wt% Ti 3 C 2 T x , representing a 66% increase compared to that of SnSe. This work sheds light on the thermoelectric performance improvement of polycrystalline SnSe by controllably incorporating two-dimensional MXene.
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SCIENCE OF THE TOTAL ENVIRONMENT
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2022
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IF 10.753
Ao Wang,Hang Xu,Jiawei Fu,Tao Lin,Jun Ma,Mingmei Ding,Li Gao
The introduce of a nanomaterial interlayer between the substrate and polyamide is identified as a promising strategy to construct highly performed membranes. Two-dimensional (2D) materials are potential candidates as interlayer for advanced thin-film nanocomposite interlayer (TFNi) membranes. Nevertheless, low permeability, selectivity and long-term stability are still critical issues in TFNi membrane manufacture. Herein, a scalable approach for constructing TFNi membranes was implemented using stacked MXene nanosheets as interlayer, wherein the Fe 3 O 4 nanoparticles worked as the sacrificial template to regulate the interlayer spacing of the 2D channels. SEM , XPS, water contact angle, and zeta potential were used to characterize the physical and chemical properties of prepared TFNi membranes, and the results shows that the presence of MXene interlayer increased the hydrophilicity, thinness and roughness of polyamide layer compared to that of pure TFC membranes. Besides, the enlarged interlayer channel after the sacrifice of the Fe 3 O 4 nanoparticles greatly boosted the transport of the water molecules. The resultant membranes exhibited nearly double fold of water flux (66.4 ± 3.45 L·m −2 ·h −1 ) and higher selective separation factor (48.4) compared with those prepared without interlayer, while the outstanding salt rejection (>97 %) was maintained. This work achieves an innovative strategy for multifunctional polyamide nanofiltration membrane construction.
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