CHEMICAL ENGINEERING JOURNAL
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2025
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IF 13.2
Yi Yao,Zixin Gao,Zhongjie Pan,Yanping Zhong,Lili Qin,Kexin Zhao,Shuhan Liu,Shengqing Zhang,Haoyang Han,Feiying Yin,Ruizheng Liang,Jinmin Zhao,Li Zheng
Platinum (Pt)-based nanozymes that effectively exert antioxidant effects exhibit great potential in the treatment of osteoarthritis (OA). However, these nanozymes are easy to agglomerate and have low catalytic efficiency, which can hardly meet the criterion of clinical therapy. To achieve efficient ROS removal, this study develops a novel ultrasound (US)-responsive piezoelectric nanozyme (MOF(Hf)-Pt) based on Pt with multi-enzyme mimicking activities and metal-organic frameworks (MOFs) with excellent piezoelectric properties. Results show that MOF(Hf)-Pt has excellent piezocatalytic enzyme activity, which can be adjusted by varying the intensity and time of US. Mechanistically, MOF(Hf)-Pt can increase ATP output and restore mitochondrial function, thereby reducing inflammatory factor levels. In vivo studies also reveal that under suitable US action, MOF(Hf)-Pt nanozymes can effectively inhibit the deterioration of OA, with reductions in OARSCI scores of 76.90 % and 82.66 % after 4 and 8 weeks, respectively. Particularly, the piezoelectric catalytic effect generated by MOF(Hf)-Pt can reverse oxidative stress-induced articular cartilage damage and promote cartilage regeneration, making it a promising candidate for OA treatment.
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JOURNAL OF APPLIED POLYMER SCIENCE
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2025
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IF 2.8
Jingguang Wang,Yutao Lin,Tao Wang,Zhenze Xie,Wenxin Guo,Chang Du
Cancer treatment techniques often struggle to simultaneously address the issues of significant impact from cancer heterogeneity, poor resistance to drugs, and non-selective drug toxicity. Therefore, cancer treatment strategies based on nanoplatforms with multiple responsive properties have attracted wide attention due to their broad applicability and minimal side effects on normal cells. Herein, we constructed a nano iron-based metal–organic framework loading Pt and coated with polydopamine (Fe-MOF-NH 2 @Pt@PDA) using the solvothermal method for multimodal cancer therapy. The Pt and Fe could leverage the unique weak acidity and overexpression of hydrogen peroxide in the tumor cell to generate reactive oxygen species (ROS) for chemodynamic therapy (CDT). Additionally, Pt and Fe gave its peroxidase-like activity to produce oxygen, improving the hypoxic environment in the tumor microenvironment. Due to Pt, Fe-MOF-NH 2 @Pt@PDA achieved excellent sonodynamic therapy (SDT) under ultrasound (US) stimulation. Under US, more ROS were generated, enhancing the anticancer effect of CDT. Moreover, Fe-MOF-NH 2 @Pt@PDA produced an excellent photothermal effect under 808 nm near-infrared (NIR) irradiation for photothermal therapy (PTT). Furthermore, Fe-MOF-NH 2 @Pt@PDA exhibited good biocompatibility. Taken together, the nano Fe-MOF-NH 2 @Pt@PDA with synergistic CDT, SDT, and PTT combined treatment was a promising biomaterial for non-invasive clinical cancer therapy.
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ENVIRONMENTAL SCIENCE & TECHNOLOGY
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2025
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IF 11.3
Chonghui Zhu,Yu Liang,Chenshuai Han,Zhaorui Zhang,Huashuai Hu,Minghui Yang
Efficient monitoring of hydrogen sulfide (H2S) in wastewater is essential for preventing environmental contamination and safeguarding public health. Current methods for assessing sulfide levels are limited by complex, time-consuming processes. Here, we introduce a Pt/CrWN2-based electrochemical gas sensor designed for real-time detection of H2S gas, offering a fast, reliable, and cost-effective solution for monitoring sulfate concentrations in wastewater. It exhibits rapid response and recovery times (3.6/3.5 s), high sensitivity (0.295 μA/ppm), and stability (90 days), even after direct exposure to sewage. Our findings demonstrate the potential of this system for continuous water quality assessment, providing valuable insights into pollution dynamics and enhancing environmental monitoring capabilities.
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CHEMICAL ENGINEERING JOURNAL
·
2025
·
IF 13.2
Qiaolan Shi,Lu Yuan,Joop de Vries,Brandon W. Peterson,Jian Liu,Yijin Ren,Henny C. van der Mei
Due to the high resistance and complexity of biofilms, alternatives to traditional antibiotic treatments are urgently needed. Here, we investigated whether Pt nanoparticles grown on Bi 3 O 4 Br nanosheets (Pt NP /Bi 3 O 4 Br) can enhance the efficacy of the antibiotic ampicillin against biofilm-associated infections. X-ray photoelectron spectroscopy revealed abundant oxygen vacancies in the Bi 3 O 4 Br nanosheet creating an ideal surface for Pt nanoparticles growth. The obtained Pt NP /Bi 3 O 4 Br nanozyme had a uniform Pt nanoparticle distribution confirmed by X-ray powder diffraction and transmission electron microscopy with high-angle annular dark-field scanning. Compared to Bi 3 O 4 Br nanosheets alone, the nanozyme demonstrated significantly higher catalytic activity for reactive oxygen species generation facilitated by efficient electron transfer from Pt nanoparticles. When combined with ampicillin, Pt NP /Bi 3 O 4 Br nanozyme significantly enhanced bactericidal efficacy against both Gram-positive Staphylococcus aureus and Gram-negative Escherichia coli biofilms in vitro as shown by reduction in biofilm thickness and colony-forming units. In a murine skin infection model, the combination accelerated wound healing following S. aureus infection. Additionally, the combined treatment selectively reduced the pathogen Streptococcus mutans in human ex vivo oral biofilms while preserving the healthy human microbiome indicating potential applications in dental care. In conclusion, this work demonstrates that nanozyme-enhanced antibiotic therapy offers a promising strategy to combat biofilm-associated infections and antibiotic resistance.
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JOURNAL OF CATALYSIS
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2025
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IF 6.5
Yuxuan Xie,Zhao Li,Ziruo Zeng,Lina Sun,Shuangyou Bao,Xin Sun,Kunlin Li,Chi Wang,Fei Wang,Ping Ning,Kai Li
To investigate the mechanism of the role of active center size on the selectivity of methyl mercaptan (CH 3 SH) and methane (CH 4 ) in the deep hydrogenation reaction of carbon disulfide (CS 2 ), it was first derived from DFT calculations that the Pt cluster geometries showed a decreasing and increasing pattern on the energy barriers of the two key hydrogenation steps: (I) HCSS* to HCSSH* and (II) deep hydrogenation of CH 2 S* to CH 3 SH. For further validation, we synthesized Pt NPs with varied average sizes (1.7–4.0 nm) using a reduction-agglomeration strategy to probe the source of size sensitivity at low Pt loading. It was found that the active centers of Pt NPs located in the 2.0–3.0 nm region have the highest proportion of medium-coordinated Pt sites, which can effectively promote hydrogen spillover and enhance the HCSS* pathway. Finally, with this modulation strategy, the catalytic activity and selectivity were significantly improved at 1 wt% Pt loading, which exceeded that of the fresh 4 wt% Pt/Al 2 O 3 catalyst, and the long-term stable production of CH 3 SH (selectivity was maintained at 80 %) was achieved at 250 ℃ in the high-concentration CS 2 environment.
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CHEMICAL ENGINEERING JOURNAL
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2025
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IF 13.2
Yong Liu,Mingjun Han,Jianye Liu,Yaling Huang,Yisi Liu,Wenzhang Li,Yang Liu,Jie Li
The practical implementation of Li-O 2 batteries remains constrained by three persistent challenges: sluggish oxygen redox kinetics, prohibitive costs of noble metal catalysts, and insufficient activity of non-precious alternatives. Herein, we present a novel ultralow Pt (0.25 wt%) single-atom loading Co 3 O 4 nanoneedle array catalyst (Pt 1 -Co 3 O 4 ) grown on carbon cloth via an ionic substitution strategy. This material functions as an advanced self-supporting cathode for aprotic Li-O 2 batteries. Benefiting from the surface self-reconstruction induced by Pt single-atom occupied the tetrahedral central sites of Co 3 O 4 , the electronic structure of Co 3 O 4 is modified, significantly enhancing the kinetics of both the oxygen reduction reaction (ORR) and oxygen evolution reaction (OER). As a result, the Pt 1 -Co 3 O 4 cathode demonstrates excellent cycling stability and a remarkably low discharge–charge overpotential of just 0.86 V. Furthermore, the Li-O 2 battery with this cathode exhibits a high discharge-specific capacity (8.20mAh cm −2 ) and long cycling life (220 cycles, >1100 h at 0.1 mA cm −2 ), outperforming all reported Co 3 O 4 -based ORR/OER catalysts, as well as many non-noble metal catalysts, even those with significant noble metal loading. Crucially, the thin-film-like layers of discharge product Li 2 O 2 are uniformly dispersed on the Pt 1 -Co 3 O 4 nanoneedles. This reduces the adsorption energy between LiO 2 /Li 2 O 2 and Pt 1 -Co 3 O 4 compared to Co 3 O 4 , ensuring good structural stability during discharge/charge cycles and facilitating the decomposition of discharge products during recharge, thus reducing overvoltage and enhancing battery efficiency. These findings position Pt 1 -Co 3 O 4 as a promising catalyst for Li-O 2 batteries and open new avenues for the development of oxide-based single-atom catalysis.
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INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
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2025
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IF 3.9
Yi Yang,Yuxi Si,Libin Liu,Hairui Lin,Chuan Qin,Dangguo Cheng,Youwei Cheng
The chemical conversion of 5-hydroxymethylfurfural (HMF) into high-value-added products offers a potential substitute for fossil-based products, which has garnered significant attention in light of energy depletion and environmental concerns. Among the various HMF derivatives, 2,5-bis(hydroxymethyl)furan (BHMF), applicable in polyester manufacturing, pharmaceutical intermediates, biodiesel, and other sectors, can be synthesized through the C═O hydrogenation of HMF. However, the inevitable humins formation and the over-hydrogenation/hydrogenolysis constrain the further application of this process. In this study, a series of hydroxyl-enriched Pt-based catalysts have been prepared and applied in the hydrogenation of HMF. For 1% Pt/CeO2, the selectivity for BHMF over 85% can be consistently maintained at 30 °C or at a substrate concentration of 100 g/L. Experiments and characterization studies indicate that hydroxyl groups presented on the catalyst surface could protect BHMF, inhibiting side reactions and thereby increasing carbon balance and main product selectivity. This superior selective catalytic performance was further demonstrated in the C═O hydrogenation over various aromatic aldehyde substrates, providing a novel approach for biomass compounds conversion to value-added chemicals and providing a perspective for catalyst design.
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Energy Materials
·
2025
·Vol. 5
·期 6
·N
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IF 11.2
Shensong Wang,Zhiliang Zhao,Yongming Hu,Sanping Jiang,Xinyi Zhang
Direct ethanol fuel cells are considered indispensable and prospective energy storage devices due to their high volumetric energy density. Platinum (Pt) and Pt-based alloys are regarded as the most effective catalysts for both oxygen reduction reaction (ORR) and ethanol oxidation reaction. To further enhance the catalytic performance of the catalyst, it is necessary to improve the mass activity and utilization efficiency of Pt. In this work, we report a strategy for fabricating ordered mesostructured platinum-palladium alloy nanotubes (MPPNs) with high hierarchical porosity (68%) and abundant exposed active edge sites. MPPNs exhibit excellent catalytic activity and stability for ORR, with a mass activity approximately 7.4 times higher than that of the commercial Pt/C catalyst. After 20 k cycles of accelerated durability test for ORR, MPPNs demonstrate impressive retention of their original mass activity, maintaining a value of 93.9%. Furthermore, they display superior catalytic activity and stability for ethanol oxidation reactions, with a mass activity about 2.4 times higher than that of commercial Pt/C. After the 2,000 scan cycles, the mass activity remains at 84.5% of initial performance. Both experimental and theoretical studies reveal that the synergistic effect of neighboring (111) and (100) facets on the edge sites plays a critical role in enhancing the electrocatalytic selectivity, activity and stability.
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Nature Communications
·
2022
·Vol. 13
·期 1
·1-13
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IF 17.694
Tang Hongying,Geng Kang,Aili David,Ju Qing,Pan Ji,Chao Ge,Yin Xi,Guo Xiang,Li Qingfeng,Li Nanwen
A key challenge for fuel cells based on phosphoric acid doped polybenzimidazole membranes is the high Pt loading, which is required due to the low electrode performance owing to the poor mass transport and severe Pt poisoning via acid absorption on the Pt surface. Herein, these issues are well addressed by design and synthesis of effective catalyst binders based on polymers of intrinsic microporosity (PIMs) with strong hydrogen-bonding functionalities which improve phosphoric acid binding energy, and thus preferably uphold phosphoric acid in the vicinity of Pt catalyst particles to mitigate the adsorption of phosphoric acid on the Pt surface. With combination of the highly mass transport microporosity, strong hydrogen-bonds and high phosphoric acid binding energy, the tetrazole functionalized PIM binder enables an H 2 -O 2 cell to reach a high Pt-mass specific peak power density of 3.8 W mg Pt −1 at 160 °C with a low Pt loading of only 0.15 mg Pt cm −2 .
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SEPARATION AND PURIFICATION TECHNOLOGY
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2025
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IF 9
Dongdong Zhang,Jiang Zhong,Linjie Tong,Peng Chen,Xingan Jiang,Lin Wang,Xiaoqiang Zhan,Hongli Yang,Hongxian Zhu,Yong Luo,Weiyou Yang
Single-atom catalysts (SACs) show great potential in enhancing CO 2 photoreduction activity, thanks to their exceptional atomic efficiency and outstanding catalytic properties. However, the high surface energy of SACs presents a significant challenge, as the single atoms often tend to be aggregated during the synthesis and catalytic processes, thus making them be difficult for efficient and sustainable performance. Herein, we report a strategy to stabilize SACs on photocatalytic materials enabled by creating oxygen vacancy defects on the matrix surface, which allow the single-atom platinum (Pt) uniformly and solidly anchored on BiOBr nanosheets (NSs). The as-synthesized Pt-BiOBr-V O achieves a dramatic CO 2 photoreduction activity with a CO production rate of 93.5 μmol·g −1 ·h −1 and 75 % selectivity, outperforming those of most BiOBr-based photocatalysts ever reported. The overall enhanced catalytic behaviors are mainly attributed to the synergistic effect between the Pt single atoms and V O , which optimizes the electronic structure of BiOBr with improved charge transfer and extended lifetime of photogenerated carriers. Moreover, the created oxygen vacancies could act as the electron absorption centers, thus accelerating the activation of CO 2 and the formation of intermediates. The present work provides new insights on rationally designing highly efficient and stable photocatalysts based on defect engineering for developing sustainable green energy.
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ACS Sensors
·
2025
·
IF 9.1
Chonghui Zhu,Huan Wang,Zhaorui Zhang,Chenshuai Han,Huashuai Hu,Minghui Yang
Food spoilage leads to significant waste and poses serious health risks, yet real-time monitoring solutions remain limited throughout the supply chain and storage. Herein, we develop a Pt/Fe-TiN-based fuel cell gas sensor for highly sensitive and selective detection of hydrogen sulfide (H2S), a key indicator of meat spoilage. Fe doping in TiN effectively modulates the electronic structure of Pt, enhancing H2S sensitivity and mitigating humidity interference. The Pt/Fe-TiN sensor achieves a detection limit of 100 ppb and remains fully operational even at −18 °C. Compared to commercial Pt/C electrodes, it exhibits superior stability, retaining over 97% of its sensitivity after 60 days under high humidity. Furthermore, a real-time H2S monitoring device integrated with a smartphone interface was developed for continuous spoilage detection in meat storage. This work provides a practical, real-time sensing platform for food safety monitoring, contributing to reduced waste and improved supply chain transparency.
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Small
·
2025
·
IF 12.1
Zhaoxin Li,Zewen Shen,Haotian Zhang,Chumin Yan,Lisha Yin,Yezi Hu,Guangtong Hai,Guixia Zhao,Xiubing Huang
Terminal bifunctional aliphatic compounds are important intermediates for synthesis of drugs, food additives, polymers, while oxidative conversion from diols in mild conditions and the insight mechanism are rarely investigated. In this work, Pt-loaded BiVO 4 (4%Pt/S-BVO and 4%Pt/H-BVO) is proposed to be utilized for the oxidation of 1,6-hexanediol (1,6-HDO). In dark conditions, the electronic metal-support interactions between Pt and BiVO 4 and abundant oxygen vacancies (OVs) activated C-H and O 2 , leading to the primary oxidation of terminal hydroxyl group of 1,6-HDO. The generated·O 2 − radicals enable further oxidation of aldehyde group to carboxyl group. With illumination, the photo-generated holes promoted oxidation of hydroxyl group to aldehyde group while the increased ·O 2 − radicals promoted the oxidation of aldehyde group to carboxyl group. The introduced heat originated from the photothermal effect and an additional heat source is supposed to boost the mass transfer of molecules and ·O 2 − radicals. In particular, with more abundant OVs and exposed {040} facets, more ·O 2 − radicals, and improved charge separation, 4%Pt/S-BVO exhibit 90% conversion of 1,6-HDO with selectivity of 98.6% to TBACs in 6 h. Those findings highlight the great promise of catalytic organics transformation by integrating solar energy to enhance the reaction efficiency.
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