JOURNAL OF ALLOYS AND COMPOUNDS
·
2022
·
IF 6.371
Wen-Fa Chen,Bin-Wen Liu,Xiao-Ming Jiang,Guo-Cong Guo
Nonlinear optical (NLO) crystals can produce tunable lasers through the direct second-harmonic generation (SHG) process, which is of great significance in modern laser technology. Herein, a new chalcogenide β -PbGa 2 S 4 ( 1 ) crystallized in space group of Pna 2 1 was synthesized via high-temperature solid-state reactions. Compound 1 is composed of a three-dimensional framework [Ga 8 S 16 ] 8− with hexagonal voids filled by Pb atoms via covalent Pb–S interactions. Importantly, it exhibits promising NLO performances, such as phase-matchable SHG efficiency (0.6×AgGaS 2 @1200 nm and 0.1×AgGaS 2 @1910 nm), moderate band-gap (2.46 eV), suitable laser-induced damage threshold (3.0×AgGaS 2 ), and a broad IR transparency window (0.5–25.0 µm). SHG response of 1 is mainly attributable to the occupied S–3p and Ga–4p states and unoccupied S–3p and Pb–6p states.
研究领域:
材料科学
·
光学
✓ 已验证
DOI
高影响因子
ADVANCED MATERIALS
·
2025
·
IF 26.8
Liyan Wang,Shuai Liu,Ziyuan Liu,Mengjiao Han,Jiehui Tian,Yuchuan Xiao,Qitian Chen,Debo Hu,Lizhi Zhang,Lixing Kang,Qing Dai
Beta-phase gallium sesquioxide ( β -Ga 2 O 3 ), possessing an ultrawide bandgap and high breakdown voltage, exhibits strong potential for deep-ultraviolet photodetection and high-power electronics. However, nanometer-scale line defects, prevalent in β -Ga 2 O 3 growth, degrade device performance by increasing leakage currents and reducing breakdown voltages, thus termed “killer defects”. Critically, the impact of these defects at the atomic scale remains unclear due to limited characterization and a lack of detailed understanding. Here, the observation of novel conductive atomic line defects is reported within β -Ga 2 O 3 nanoflakes using near-field infrared imaging. Combining atomic-resolution imaging with density functional theory calculations, these defects are identified as interstitial Ga atoms migrating along the c -axis. These atomic line defects exhibit a broadband infrared response and quenched cathodoluminescence, indicative of significantly enhanced local conductivity. This elevated conductivity enables subsurface near-field detection of the defects and remote excitation of phonon polaritons in a hexagonal boron nitride ( h BN) capping layer. These findings underscore the distinct conductivity of atomic-scale line defects, emphasizing the need for their controlled management during material synthesis and device fabrication, while simultaneously suggesting opportunities for their exploitation in nanophotonic applications.
研究领域:
材料科学
·
物理学
·
纳米光学
✓ 已验证
DOI
PubMed
高影响因子
Food & Function
·
2015
·Vol. 6
·期 10
·3291-3295
·
IF 2.791
Hui-da Wan,Yong-mei Xia
Enzymatic hydrolysis and transgalactosylation of stevioside (St) were investigated using a β-galactosidase from Sulfolobus sp. The hydrolysis yielded steviol as the main final product. Under the optimal transgalactosylation conditions, the highest conversion of stevioside was 87.3% with lactose as a donor, several galactosylated products (St-Gals) were obtained. Metal ions such as Na+, K2+, Ca2+, Ba2+, Mn2+ and Mg2+ (2 mM) did not affect the transgalactosylation activity, while Fe2+, Fe3+ and Cu2+ reduced the transgalactosylation activity of β-galactosidase to 64%, 33% and 18%, respectively.
研究领域:
生物化学
·
食品科学
✓ 已验证
DOI
高影响因子
BIOPOLYMERS
·
2012
·Vol. 97
·期 12
·988-997
·
IF 2.87
Qingye Liu,Xiaojuan Xu,Lina Zhang
We have firstly demonstrated the renaturation process of dissociated single chains of lentinan (s-LNT) and the variable conformations of the renatured LNT (r-LNT). The results from ultrasensitive differential scanning calorimetry and circular dichroism revealed that the variable structures including perfect triple helix, defective triple helix containing duplex segment, and single chains occurred in the renaturation of s-LNT, depending on the renaturation time, solvent composition, molecular weight, and the mode of renaturation. When water was added into s-LNT/dimethylsulfoxide (DMSO) to reach 95% (v/v), the classic low-temperature intra-triple-helical conformational transition at ∼10 ° C ( T 1 ) appeared within 4 h, indicative of a rapid reconstruction of triple helical structure. Besides, one newly endothermic peak at ∼43 ° C ( T 2 ) simultaneously occurred, which was first ascribed to the melting of duplex segment in the imperfect triplex. The duplex stretches disappeared when DMSO reached 50%, in which single chains coexisted with triplex. Moreover, the duplex segment disappeared by slowly dropping water into s-LNT/DMSO. This work suggested that the structure of r-LNT could be controllable, and provided important information for their successful development and application in polymer and life science. © 2012 Wiley Periodicals, Inc. Biopolymers 97:988–997, 2012.
研究领域:
生物化学
·
分子生物学
·
聚合物科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
·
2014
·
IF 2.129
Na Li,Jiang-Kun Dai,Hong-Tao Du,Mao-Sen Yuan,Ji-Wen Zhang,Jun-Ru Wang
A novel sensing system based on the β -carboline core has been designed and synthesized for Hg 2+ detection in water. We have demonstrated that a straight forward methodology can provide rapid, sensitive and selective recognition (cross-contamination experiments) for Hg 2+ over a wide pH range. The vivid fluorescence change from blue to colorless can be clearly discriminated by the naked eye. Furthermore, there is a good negative correlation between the fluorescent intensity and the concentration of Hg 2+ in the range 1.0 × 10 −6 M–7.0 × 10 −6 M. β -Carboline as a fluorophore synthesized via this route also provides a new strategy for the design of novel fluorescence probes and fluorochromes.
研究领域:
分析化学
·
环境科学
·
材料科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ACS Omega
·
2017
·
IF 0
Yijun Li,Xinyu Wen,Min Nie,Qi Wang
Dendritic β-nucleating agent (β-NA) can readily manipulate the formation of dendritic β-crystal with a unique toughening effect on polypropylene (PP) to drastically enhance the ductility. However, by the current method, the geometric size is too large to fully perform the nucleating efficiency. In this study, by comparatively investigating the effect of molecular weight of PP and diffusion of β-NAs in a PP melt, we proposed a novel carrier strategy that selective enrichment of β-NAs in a PP carrier was followed by directed migration into polymer matrix. Accordingly, the growth of NAs was controlled by the release from the PP carrier, which decreased the available amount of β-NAs during the growth stage. In this case, the viscosity difference between PP carrier and matrix determined the interfacial movement of β-NAs. When the PP carrier and matrix had same molecular weight, the diffusion and release became favorable to facilitate the formation of the dense and fine dendritic aggregates. As a result, the relative content of β-crystals reached 92%, with a drastic increase of ∼82% in the optimal condition compared to the directed compounded PP/β-NAs sample. This study can open a new avenue to tailor the topologies of β-NAs and the ensuing β-crystals for high-performance PP products.
研究领域:
材料科学
·
高分子化学
✓ 已验证
产品关联
DOI
PubMed
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
·
2018
·Vol. 42
·期 1
·61-70
·
IF 2.784
Yuhuan Ma,Wenwei Zheng,Houhuang Chen,Xiang Shao,Pingdong Lin,Xianxiang Liu,Xihai Li,Hongzhi Ye
The present study investigated the mechanism underlying the effects of glucosamine (GlcN) on the proliferation of chondrocytes isolated from the knee cartilage of Sprague‑Dawley rats. Chondrocytes were treated with various concentrations of GlcN or without GlcN. The effects of GlcN on chondrocyte proliferation were determined using reverse transcription‑polymerase chain reaction, western blot analysis and immunohistochemistry. The results indicated that GlcN significantly improved chondrocyte viability, accelerated G1/S transition during progression of the cell cycle and promoted the expression of cell cycle regulatory proteins, including cyclin D1, cyclin‑dependent kinase (CDK)4 and CDK6, thus indicating that GlcN may promote chondrocyte proliferation. Furthermore, GlcN upregulated the expression levels of Wnt‑4, Frizzled‑2 and β‑catenin, and downregulated the expression of glycogen synthase kinase‑3. GlcN also promoted β‑catenin translocation; β‑catenin is able to activate numerous downstream target genes, including cyclin D1. To determine the role of the Wnt/β‑catenin signaling pathway in chondrocyte proliferation, the Wnt/β‑catenin signaling pathway was inhibited using Dickkopf‑1 (DKK‑1), after which chondrocytes were treated with GlcN. The results demonstrated that the expression levels of β‑catenin and cyclin D1 were decreased in chondrocytes treated with DKK‑1 and GlcN. These results suggested that GlcN may promote chondrocyte proliferation via the Wnt/β‑catenin signaling pathway.
研究领域:
药理学
·
细胞生物学
·
分子生物学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2019
·
IF 6.361
Qi Wang,Chenlu Zhang,Hong Wu,Qiaoyuan Gao,Ran Duan,Chuncheng Chen
Bi 2 O 2 CO 3 was co-decorated by β-phase AgI and Bi 2 O 3 forming visible-light-active AgI(β)/Bi 2 O 3 (β)-Bi 2 O 2 CO 3 composite via simply calcining AgI/Bi 2 O 2 CO 3 . The calcination temperature and time played vital role in regulating the structure as well as photocatalytic performance. Optimal AgI(β)/Bi 2 O 3 (β)-Bi 2 O 2 CO 3 was obtained after 325 ◦ C calcination for 2 h with 5% AgI. The ratio of Bi 2 O 3 to Bi 2 O 2 CO 3 was estimated to be ca. 3:1 on the catalyst surface. The transformation process for n -type Bi 2 O 2 CO 3 to p-type Bi 2 O 3 (β) was monitored and verified by flat band potential measurements. Due to the presence of p-n junctions between p-type Bi 2 O 3 (β), n -type AgI(β) and Bi 2 O 2 CO 3 , the optimized ternary composite displayed enhanced photocurrent density and reduced charge transfer resistance, which were beneficial for photocatalytic applications. Despite of decreased specific surface area, dramatically enhanced photocatalytic performance can be observed for simultaneous removal of Cr(VI) and phenol . For example, the estimated k Cr(VI) and k phenol on AgI(β)/Bi 2 O 3 (β)-Bi 2 O 2 CO 3 were 3.3 and 2.2 times relative to those on uncalcined AgI/Bi 2 O 2 CO 3 , respectively. The optimized composite also displayed good stability in 4 successive cyclic runs.
研究领域:
材料科学
·
环境科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF SEPARATION SCIENCE
·
2015
·Vol. 38
·期 11
·1813-1821
·
IF 2.737
Qiaoxuan Zhang,Jialiang Guo,Yuan Xiao,Jacques Crommen,Zhengjin Jiang
To further evaluate the feasibility and applicability of the one-pot strategy in monolithic column preparation, two novel β-cyclodextrin-functionalized organic polymeric monoliths were prepared using two β-cyclodextrin derivatives, i.e. mono(6-amino-6-deoxy)-β-cyclodextrin and heptakis(6-amino-6-deoxy)-β-cyclodextrin. In this improved method, mono(6-amino-6-deoxy)-β-cyclodextrin or heptakis(6-amino-6-deoxy)-β-cyclodextrin reacted with glycidyl methacrylate to generate the corresponding functional monomers and were subsequently copolymerized with ethylene dimethacrylate. The polymerization conditions for both monoliths were carefully optimized to obtain satisfactory column performance with respect to column efficiency, reproducibility, permeability, and stability. The obtained poly(glycidyl methacrylate-mono(6-amino-6-deoxy)-β-cyclodextrin- co -ethylene dimethacrylate) and poly(glycidyl methacrylate-heptakis(6-amino-6-deoxy)-β-cyclodextrin- co -ethylene dimethacrylate) monoliths exhibited a uniform structure, good permeability, and mechanical stability as indicated by scanning electron microscopy and micro-high-performance liquid chromatography experimental results. Because of the probable existence of multi-glycidyl methacrylate linking spacers on the poly(glycidyl methacrylate-heptakis(6-amino-6-deoxy)-β-cyclodextrin- co -ethylene dimethacrylate) monolith, the effect of the ratio of glycidyl methacrylate/heptakis(6-amino-6-deoxy)-β-cyclodextrin was especially studied, and satisfactory reproducibility could still be achieved by strictly controlling the composition of the polymerization mixture. To investigate the effect of the degree of amino substitution of β-cyclodextrin on column performance, a detailed comparison of the two monoliths was also carried out using series of analytes including small peptides and chiral acids. It was found that the β-cyclodextrin-functionalized monolith with mono-glycidyl methacrylate linking spacers demonstrated better chiral separation performance than that with multi-glycidyl methacrylate linking spacers.
研究领域:
分析化学
·
材料科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
PHYTOTHERAPY RESEARCH
·
2025
·
IF 6.3
Yichao Du,Junjie Bai,Tingting Ma,Ziming Wu,Pengru Wang,Xiaolin Zhong,Wenguang Fu,Shuixiang He
Liver fibrosis, a pivotal pathological feature in the progression of chronic liver injury, currently lacks effective therapies. Sinomenine (SIN), a bioactive alkaloid derived from traditional Chinese medicine, demonstrates diverse pharmacological properties. However, its therapeutic potential and mechanisms in liver fibrosis remain inadequately characterized. This study investigates the anti-fibrotic effects of SIN and its underlying molecular mechanisms. The anti-fibrotic efficacy of SIN was evaluated in two murine models of liver fibrosis induced by carbon tetrachloride (CCl 4 ) or bile duct ligation (BDL), along with transforming growth factor-beta 1 (TGF-β1)-stimulated rat hepatic stellate cells (HSC-T6). Serum biochemical markers, histopathological analyses (Hematoxylin–Eosin, Sirius red, and Masson's trichrome staining), immunofluorescence, and immunohistochemistry were employed to assess hepatic injury and collagen deposition. Western blotting elucidated molecular mechanisms. SIN administration significantly attenuated hepatic injury in CCl 4 - or BDL-induced mice, as evidenced by reduced transaminase levels and improved histopathological features. In both in vivo and in vitro models, SIN suppressed fibrogenesis by decreasing collagen deposition and downregulating expression of α-smooth muscle actin (α-SMA), matrix metalloproteinase 2 (MMP2), and collagen I. Mechanistically, SIN inhibited the TGF-β/SMAD pathway through reduced phosphorylation of SMAD2/3 and attenuated c-JUN signaling via diminished phosphorylated c-JUN levels. Pretreatment with TP0427736 (a SMAD2/3 inhibitor) or SP600125 (a c-JUN inhibitor) synergistically enhanced SIN-mediated α-SMA suppression in HSC-T6 cells. SIN ameliorates liver fibrosis through inhibition of TGF-β/SMAD and c-JUN signaling pathways. These findings position SIN as a promising therapeutic candidate for liver fibrotic disorders.
研究领域:
药理学
·
肝脏病学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
CERAMICS INTERNATIONAL
·
2012
·
IF 1.751
Lin Gan,Zhi-Yong Mao,Yu-Qiang Zhang,Fang-Fang Xu,Ying-Chun Zhu,Xue-Jian Liu
Ce 3+ -doped β-SiAlON blue phosphors with composition of Ce x Si 6− z Al z O z N 8− z (0.2≤ z ≤4) at a fixed x =0.01 were synthesized by the gas pressure sintering method. The phases and photoluminescence properties were found to be directly correlated to the z value. Higher z value would result in the formation of AlN polytypoid impurity phases. The optimal z value resides in the range 0.3≤ z ≤0.5, by which high purity of β-SiAlON phase, good crystallinity and fine grain size were obtained, leading to the best luminescence properties. These phosphors could be a good candidate for application in white light-emitting diodes using InGaN-based near–ultraviolet chips.
研究领域:
材料科学
·
光学
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF HAZARDOUS MATERIALS
·
2022
·
IF 14.224
Long Kong,Ruixin Yan,Min Liu,Junqing Xu,Takeshi Hagio,Ryoichi Ichino,Liang Li,Xinde Cao
In this study, β-Cyclodextrin (CD) modified Fe 3 S 4 nanomaterials were synthesized by a one-step facile strategy and investigated for the removal of Cr(VI). The resulted CD-Fe 3 S 4 exhibited enhanced removal efficiency toward Cr(VI) than bared Fe 3 S 4 with a maximum capacity of 220.26 mg·g -1 as the molar ratio of CD-to-Fe 3 S 4 at 0.2. The effective performance of CD-Fe 3 S 4 toward Cr(VI) could well maintain under oxic conditions and a wide pH range of aqueous solution. A high selectivity for Cr(VI) was achieved in the presence of coexisting cations and anions. More significantly, a single treatment step of CD-Fe 3 S 4 effectively removed chromium from actual electroplating wastewater to the detection limit of 0.004 mg·L -1 that far below the WHO limitation of Cr (VI) (<0.05 mg·L -1 ) combing with the rapid magnetic separation without adjusting the pH value of wastewater at 7. The effective removal of Cr (VI) by CD-Fe 3 S 4 involved a complex process of surface adsorption/reduction, and solution homogenous reduction and subsequent sequestration of Cr(III) achieving the effective removal of aqueous total Cr. The superior Cr (VI) removal capability and facial separation of CD-Fe 3 S 4 attained its prominent potential application as an effective material for the Cr(VI) removal.
研究领域:
环境科学
·
材料科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）