RSC Advances
·
2017
·Vol. 7
·期 68
·42884-42890
·
IF 3.108
Weiping Wu,Yuting Fang,Chenchen Zhu,Shiyu Chen,Ting Li,Lei Wu,Ning Bao,Yang Liu,Haiying Gu
To improve electron transfer, a combination of electroactive hemoglobin (Hb) and Au nanoparticles (Au NPs) was designed to obtain nanocomposites (NCs). Cyclic voltammetry and redox probe characterization showed that Hb–Au NCs incorporating the layer-by-layer technique to improve the ration of electroactive Hb, showed a better conjugated structure, lower standard entropy, and faster electron transfer. Au entrapped in Hb on the glassy carbon electrode (GCE) also exhibited a wider linear range, and excellent reproducibility and recovery for analytical applications of hydrogen peroxide, oxygen, and trichloroacetic acid. Therefore, our research could potentially become a promising alternative by combining bioactive molecules with nanoparticles, and broaden the applications of mediator-free biosensors.
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ELECTROANALYSIS
·
2017
·Vol. 29
·期 11
·2620-2627
·
IF 2.851
Mingxia Wang,Yifei Shi,Yubin Zhang,Yang Wang,Huayu Huang,Jiangyi Zhang,Jinxi Song
Bisphenol A, an important compound that is classified as an environmental hormone, has been proven to have harmful effects on human health and ecology. A molybdenum disulfide/Au nanorod-modified glassy carbon electrode was prepared as an electrochemical sensor for the detection of bisphenol A using a simple and convenient approach. UV–Vis spectrophotometry and transmission electron microscopy were employed to characterize the composite. The electrochemical behavior of bisphenol A at the modified electrode was investigated via differential pulse voltammetry and cyclic voltammetry. The results show that bisphenol A exhibits a good electrochemical signal at the modified electrode under optimized conditions, and a good linear relationship was observed between the bisphenol A concentration and peak current within the range of 0.01–50 μM, with a detection limit of 3.4 nM. Furthermore, the fabricated electrodes showed good anti-interference, reproducibility and stability. The proposed electrochemical method was successfully applied for the detection of bisphenol A in milk and water samples, and its potential for applications in pollutant detection was demonstrated.
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FOOD CHEMISTRY
·
2024
·
IF 8.5
Yuting Guan,Siyu Wang,Guanghua Lei,Zikang Hu,Hengye Chen,Huiwen Gu,Xiaoli Yin,Yuanbin She,Wanjun Long,Haiyan Fu
Enshi Yulu green tea (ESYL) is the most representative traditional steamed green tea in Enshi, Hubei. Different ESYL grades exhibit distinct flavors, tastes, and prices. In this study, a visual sensor based on 4-MPBA Au@AgNPs was developed for the rapid and accurate identification of ESYL grades. The recognition mechanism involved the binding of 4-MPBA Au@AgNPs with polyphenolic compounds in ESYL to form borate esters and the conversion of Ag + to Ag 0 , with the generated Ag 0 depositing on the surface of 4-MPBA Au@AgNPs. The results showed that the sensor can amplify the color differences of different grades of ESYL. The visual results were also validated by the partial least squares discriminant analysis model, demonstrating an enhancement in recognition accuracy from 68.2 % to 95.5 % compared to the original extraction solution. The colorimetric sensor developed in this study is expected to provide a new approach for traceability research of other foods.
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Biosensors-Basel
·
2025
·Vol. 15
·期 1
·49
·
IF 5.6
Yijiong Xue,Chengqi Bao,Hui Liu,Fanghui Ma,Minghui Yang,Xiaoqing Li
A fluorescence probe for “switch-on” detection of alkaline phosphatase (ALP) was developed based on Au nanoclusters anchored MnO2nanosheets (Au NCs-MnO2NSs), which were synthesized using bovine serum albumin (BSA) as template through a simple one-pot approach. In the sensing system, MnO2NSs function as both energy acceptors and target identifiers, effectively quenches the fluorescence of Au NCs via fluorescence resonance energy transfer (FRET). The presence of ALP catalyzes the hydrolysis of L-ascorbic acid-2-phosphate (AAP) to ascorbic acid (AA), reducing MnO2NSs to Mn2+and facilitate the fluorescence recovery of Au NCs. The fluorescence assay offers the advantages of facile preparation, cost-effectiveness, good specificity, and high sensitivity. Moreover, the assay exhibits a broad linear range (0.005 U/mL to 8 U/mL) for ALP detection with a remarkable limit of detection of 0.0015 U/mL. Notably, this assay demonstrates promising applicability for detection ALP in human serum samples, thereby providing valuable potential for clinical applications.
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TALANTA
·
2024
·
IF 5.6
Siyu Wu,Hongyun Ma,Xiaoyan Chen,Wen Zhong,Yingying Gu,Yuqing Miao,Yarui An
Here, a label-free immunosensor was conducted using rGO/Collard-like Bi 2 S 3 @Au nanocomposite system to detect carbohydrate antigen 19-9 (CA19-9) as a diagnostic biomarker for Pancreatic cancer. The unique morphology of Collard-like Bi 2 S 3 increases its specific surface area, which allows it to immobilize more materials and biomolecules on its surface. To realize the covalent bonding of bismuth-based materials with biomolecules, bismuth-based materials were functionalized by Au NPs. Besides, the superior electrochemical activity and large specific surface area of Bi 2 S 3 @Au improved the stability of the sensor, which made it an ideal candidate for regulating the sensing interface in this study. Meanwhile, reduced graphene oxide (rGO) with remarkable electrical conductivity to improve the current response of the sensing interface, thus broadening the linear range of the immunosensor. Based on the above materials, a label free electrochemical immunosensor was constructed for detecting CA19-9. Under optimal conditions, it displays good linear relationship within the range of 0.01 U mL −1 to 100 U mL −1 , the detection limit being 0.0012 U mL −1 . Additionally, the immunosensor prepared in this work is characterized by superior interference immunity, reproducibility and storage stability, and has yielded satisfactory recovery rate in testing the serum samples of patients.
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ACS Applied Nano Materials
·
2024
·
IF 5.3
Junnan Wang,Zeyu Wang,Jindou Shi,Chen Zhang,Yun Zhou,Zheyuan Da,Arshad Saleem Bhatti,Minqiang Wang
In the realm of surface-enhanced Raman scattering (SERS) research, the precise detection and effective cleansing of substances are critical. This study introduces a novel Au nanotriangle/Cs2AgBiBr6 (Au NT/CABB) SERS array, synthesized through a meticulous two-step process, which demonstrates remarkable SERS effectiveness. Using Rhodamine 6G (R6G) as the probe molecule, this substrate accurately detects target molecules and achieves an exceptional detection threshold of 1 × 10–13 M. The integration of CABB into the substrate endows it with photocatalytic properties, thereby accelerating the degradation of adsorbed signaling molecules and significantly enhancing the reusability of the Au NT/CABB arrays. Furthermore, the arrays exhibit outstanding SERS and photocatalytic performance with methylene blue (MB) and MB&R6G mixed solutions, distinguishing between the two signal molecules with high fidelity. Additionally, the SERS enhancement mechanism of the Au NT/CABB array is analyzed by the finite-difference time-domain (FDTD) simulation and energy band structure. These findings highlight the substrate’s dual capability in leveraging both electromagnetic and chemical enhancement mechanisms for superior SERS performance, complemented by an integrated photocatalytic self-cleaning feature, making it a promising candidate for environmental detection applications.
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BIOSENSORS & BIOELECTRONICS
·
2025
·
IF 10.5
Xu Yang,Fan Wu,Haowei Huang,Guojun Zheng,Hongyu Zhang,Wenrong Cai,Junyao Li,Zheng-Zhi Yin,Yong Kong
Wearable sensors can easily enable real-time and noninvasive glucose (Glu) monitoring, providing vital information for effectively preventing various complications caused by high glucose level. Here, a wearable sensor based on nanozyme-catalyzed cascade reactions is designed for Glu monitoring in sweat. Au nanoparticles (AuNPs) are anchored to the carbonated zeolitic imidazolate framework-8 (ZIF-8-C), endowing the sensor with Glu oxidase (GOx)-like and peroxidase (POD)-like activity. A flexible screen-printed carbon electrode (SPCE) is decorated with the resultant AuNPs@ZIF-8-C, which is further modified with biocompatible and swellable calcium alginate (CA) gels for the preparation of the wearable Glu sensor. The linear range for Glu detection is 10∼300 μM with a limit of detection (LOD) of 4.99 μM, which covers the physiological Glu concentration range in human sweat (10–200 μM). The developed wearable Glu sensor can fit well with the skin tissues due to the flexibility of the SPCE, and thus it can be successfully applied in real-time and noninvasive monitoring of Glu in human sweat. Additionally, the wearable Glu sensor exhibits high antibacterial activity resulted from the generated hydroxyl radicals (·OH), enabling long-term Glu monitoring in sweat.
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JOURNAL OF CATALYSIS
·
2024
·
IF 6.5
Shengqiang Zhou,Tianliang Lu,Lipeng Zhou,Xiaomei Yang
Au/Sn-zeolite catalysts showed high activity for selective conversion of glycerol to methyl lactate, but suffered from poor stability under the reaction conditions in our previous report (ACS Catal. 2017, 7, 7274). Encapsulation of Au nanoparticles within zeolite is a promising strategy to enhance their stability in catalytic reaction. Herein, one-pot synthesis of Au@Snβ was achieved by a mercaptosilane-assisted hydrothermal synthesis method. The protocol involves crystallization of Snβ synthesis gels around coordinated Au precursors, resulting in Snβ framework constraining Au coordination complexes. The confinement of small (∼2.89 nm) and uniform Au particles within Snβ was achieved. The bifunctional catalyst composed of oxidative sites (Au) and Lewis acid sites (Sn) gave 77.3 % methyl lactate (MLA) yield from the base-free selective conversion of glycerol (GLY). The TOF value of Au@Snβ was higher than that of Au/Sn-zeolite in our previous report. Moreover, the special structure protects Au nanoparticles from sintering or agglomeration and improves the stability and recyclability in selective oxidation of GLY to MLA.
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ACS Applied Materials & Interfaces
·
2015
·
IF 6.723
Jing Li,Wenjing Wang,Liang Zhao,Li Rong,Shijie Lan,Hongchen Sun,Hao Zhang,Bai Yang
Despite the success of galvanic replacement in preparing hollow nanostructures with diversified morphologies via the replacement reaction between sacrificial metal nanoparticles (NPs) seeds and less active metal ions, limited advances are made for producing branched alloy nanostructures. In this paper, we report an extended galvanic replacement for preparing branched Au–Ag NPs with Au-rich core and Ag branches using hydroquinone (HQ) as the reductant. In the presence of HQ, the preformed Ag seeds are replaceable by Au and, in turn, supply the growth of Ag branches. By altering the feed ratio of Ag seeds, HAuCl4, and HQ, the size and morphology of the NPs are tunable. Accordingly, the surface plasmon resonance absorption is tuned to near-infrared (NIR) region, making the branched NPs as potential materials in photothermal therapy. The branched NPs are further coated with polydopamine (PDA) shell via dopamine polymerization at room temperature. In comparison with bare NPs, PDA-coated branched Au–Ag (Au–Ag@PDA) NPs exhibit improved stability, biocompatibility, and photothermal performance. In vitro experiments indicate that the branched Au–Ag@PDA NPs are competitive agents for photothermal ablation of cancer cells.
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COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
·
2024
·
IF 4.9
Feihu Mu,Jin Huang,Shengpan Xu,Ruiqing Wang,Xiaozhong Chu,Zhipeng Cheng,Xujing Guo,Wei Zhao,Benlin Dai,Wenshuai Zhu
Dissolved organic matter (DOM) in black-odorous water can cause excessive growth of plants and algae, leading to deterioration of water quality. Herein, an S-scheme Au/g-C 3 N 4 /BiVO 4 heterojunction was constructed using a three-step method for DOM degradation in real black-odorous water in the presence of peroxymonosulfate (PMS). 4Au/g-C 3 N 4 /BiVO 4 /PMS exhibited highly efficient photocatalytic performance, and the DOM removal rate could reach 92.9 %, which was 19.1 and 9.9 times higher than that of g-C 3 N 4 /PMS and BiVO 4 /PMS, respectively. The changes of fluorescence components in DOM were detected using synchronous fluorescence spectra and two-dimensional correlated spectroscopy analysis, and the toxicity of catalytically treated black-odorous water was evaluated by growth inhibition of Escherichia coli . A reasonable S-scheme mechanism was suggested by theoretical calculations and photoelectrochemical tests. The S-scheme mechanism and the synergistic effect of photocatalysis and hybrid advanced oxidation process (HAOP) increased the catalytic activity of Au/g-C 3 N 4 /BiVO 4 /PMS.
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INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
·
2025
·Vol. 26
·期 3
·1348
·
IF 4.9
Yansen Li,Jingyao Chen,Chaojie Yang,Wenhao Fan,Qirong Chen,Nan Yang,Pingye Deng,Wenlei Zhai,Zhiyong Yan,Feng Wang
A novel photoelectrochemical (PEC) biosensor was proposed by preparing Au NP/MXene–BiOCl Moiré superlattice nanosheets as the probes. Upon irradiation with visible light, the probe exhibited excellent electrical conductivity as well as high photoelectric conversion efficiency. Benefitting from the excellent PEC property of the hybrid probe, sensitive and accurate detection of protein kinase activity was demonstrated with a limit of detection of 0.0029 U mL−1. This study verifies the great PEC potential of MXene hybrid nanomaterials.
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INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
·
2024
·
IF 3.8
Tianci Zheng,Yanfei Zhu,Rui Ma,Liguang Bai,He Yu,Shixi Zhao,Yufei He,Yanan Liu,Dianqing Li
Hydrogenation of unsaturated C≡C groups is a promising way to realize ethylene purification in petrochemical processes and produce value-added products. Gold catalysts are known to exhibit satisfactory selectivity toward olefins. However, it still remains a grand challenge to improve the activity and inhibit the heavy coke effect while balancing the selectivity. This article describes the construction of Cu vacancies at an abrupt surface over a Au–Cu alloy catalyst to effectively promote the activation and dissociation of hydrogen, thereby reducing the activation energy barrier. More importantly, the generation of abundant Cu vacancies contributes to the electronic interaction with the adjacent second metal to generate coordination unsaturated and electron-deficient Au species, which facilitates the desorption of product intermediates. Consequently, the activity and selectivity of the acid-etched Au3Cu1/TiO2 are much higher than those of the untreated Au–Cu and monometallic Au catalysts. This report opens up promising possibilities for engineering highly efficient heterogeneous gold catalysts.
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