基本描述

别名	4-马来酰亚胺丁酸
英文别名	M2337 \| 4-(2,5-dioxo-2H-pyrrol-1(5H)-yl)butanoic acid \| 4-Maleimidobutyric acid \| 4-Maleimidobutyric acid, >=98.0% (T) \| BP-21999 \| A8148 \| 1H-Pyrrole-1-butanoic acid, 2,5-dihydro-2,5-dioxo- \| 4-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)butanoic acid;4-Maleim
规格或纯度	≥98%
英文名称	4-Maleimidobutyric Acid
生化机理	用于修饰肽和蛋白质的 SH 标记1；用于制备酶免疫分析 (EIA) 用的新型博莱霉素类似物；膜 SH 基团探针
应用	Gamma-maleimidobutyric acid may be used as a spacer in the construction of drug and other types of bioconjugates. 4-Maleimidobutyric acid is used with N-hydroxysuccinimide ester as a bifunctional cross-linking agent. Modification reagent for thiol groups in proteins
储存温度	2-8°C储存,充氩
运输条件	冰袋运输
产品介绍	Gamma-maleimidobutyric acid may be used as a spacer in the construction of drμg and other types of bioconjμgates. 4-Maleimidobutyric acid is used with N-hydroxysuccinimide ester as a bifunctional cross-linking agent. Modification reagent for thiol groups in proteins Gamma-maleimidobutyric acid may be used as a spacer in the construction of drug and other types of bioconjugates. 4-Maleimidobutyric acid is used with N-hydroxysuccinimide ester as a bifunctional cross-linking agent. Modification reagent for thiol groups in proteins

AI解读

名称和识别符

PubChem SID	488194386
IUPAC Name	4-(2,5-dioxopyrrol-1-yl)butanoic acid
INCHI	InChI=1S/C8H9NO4/c10-6-3-4-7(11)9(6)5-1-2-8(12)13/h3-4H,1-2,5H2,(H,12,13)
InChi Key	NCPQROHLJFARLL-UHFFFAOYSA-N
Canonical SMILES	C1=CC(=O)N(C1=O)CCCC(=O)O
Isomeric SMILES	C1=CC(=O)N(C1=O)CCCC(=O)O
WGK Germany	3
PubChem CID	3404904
分子量	183.16
Beilstein号	1455876
Reaxy-Rn	1455876

化学和物理性质

溶解性	可溶于甲醇
敏感性	对湿度敏感
熔点	96 °C
分子量	183.160 g/mol
XLogP3	0.400
氢键供体数Hydrogen Bond Donor Count	1
氢键受体数Hydrogen Bond Acceptor Count	4
可旋转键计数Rotatable Bond Count	4
精确质量Exact Mass	183.053 Da
单同位素质量Monoisotopic Mass	183.053 Da
拓扑极表面积Topological Polar Surface Area	74.700 Å²
重原子数Heavy Atom Count	13
形式电荷Formal Charge	0
复杂度Complexity	264.000
同位素原子数Isotope Atom Count	0
定义的原子立体中心计数Defined Atom Stereocenter Count	0
未定义的原子立体中心计数Undefined Atom Stereocenter Count	0
定义的键立体中心计数Defined Bond Stereocenter Count	0
未定义的键立体中心计数Undefined Bond Stereocenter Count	0
所有立体化学键的总数The total count of all stereochemical bonds	0
共价键合单元计数Covalently-Bonded Unit Count	1

安全和危险性（GHS）

象形图	GHS07
信号词	Warning
危险声明	H315: 引起皮肤刺激 H319: 引起严重眼睛刺激 H335: 可能引起呼吸道刺激
预防措施声明	P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P302+P352: 如皮肤沾染：用水充分清洗。 P321: 特殊处理（请参阅此标签上的...）。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P271: 仅在室外或通风良好的地方使用。 P304+P340: 如误吸入：将人转移到空气新鲜处，保持呼吸舒适体位。 P403+P233: 存放在通风良好的地方。保持容器密闭。 P362+P364: 脱掉沾污的衣服，清洗后方可重新使用。 P264+P265: 处理后彻底洗手[和…]。不要触摸眼睛。 P337+P317: 如果眼睛刺激持续：寻求医疗帮助。 P332+P317: 如果出现皮肤刺激：请寻求医疗帮助。 P319: 如果你感到不适，请寻求医疗帮助。
WGK Germany	3
Reaxy-Rn	1455876
个人防护装备	dust mask type N95 (US), Eyeshields, Gloves

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找到8个结果

批号(Lot Number)	证书类型	日期	货号
B23021190	分析证书	22-12-02	M122236
B23021217	分析证书	22-12-02	M122236
B23021232	分析证书	22-12-02	M122236
B2303058	分析证书	22-12-02	M122236
B2303059	分析证书	22-12-02	M122236
B23031214	分析证书	22-12-02	M122236
K1814172	分析证书	22-09-15	M122236
K2223285	分析证书	21-10-22	M122236

此产品的引用文献

如何在您的发表作品中引用阿拉丁的产品和网站?

1. Jiaqi Qiu, Siyuan Xiang, Miyao Sun, Mingqian Tan. (2023) Preparation of Polysaccharide–Protein Hydrogels with an Ultrafast Self-Healing Property as a Superior Oral Delivery System of Probiotics. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, (15): [PMID:37978937] [10.1021/acs.jafc.3c05898]
2. Hailiang Chen, Chenyu Liu, Simiao Yu, Hengjun Zhou, Farishta Shafiq, Weihong Qiao. (2023) αvβ3 Receptor-targeted acid-responsive controlled-release endosome escape doxorubicin-loaded liposomes for A549/ADR treatment. COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS, 674 (131990). [10.1016/j.colsurfa.2023.131990]
3. Pengxu Kong, Jing Dong, Wenchao Li, Zefu Li, Rui Gao, Xiang Liu, Jingrong Wang, Qi Su, Bin Wen, Wenbin Ouyang, Shouzheng Wang, Fengwen Zhang, Shuyi Feng, Donglin Zhuang, Yongquan Xie, Guangzhi Zhao, Hang Yi, Zujian Feng, Weiwei Wang, Xiangbin Pan. (2023) Extracellular Matrix/Glycopeptide Hybrid Hydrogel as an Immunomodulatory Niche for Endogenous Cardiac Repair after Myocardial Infarction. Advanced Science, (2301244). [PMID:37318159] [10.1002/advs.202301244]
4. Hailiang Chen, Chenyu Liu, Simiao Yu, Hengjun Zhou, Farishta Shafiq, Weihong Qiao. (2023) Acid/GSH Dual-Responsive Endosome Escape Dual Pro-drug Micelles Targeted Synergistic Treatment for A549/ADR. LANGMUIR, 39 (22): (7660–7671). [PMID:37219917] [10.1021/acs.langmuir.3c00439]
5. Xuedi Zhang, Xue Zhao, Zheng Hua, Shanghua Xing, Jiaxuan Li, Siyuan Fei, Mingqian Tan. (2023) ROS-triggered self-disintegrating and pH-responsive astaxanthin nanoparticles for regulating the intestinal barrier and colitis. BIOMATERIALS, 292 (121937). [PMID:36495803] [10.1016/j.biomaterials.2022.121937]
6. Luo Zhenyu, Luo Lihua, Lu Yichao, Zhu Chunqi, Qin Bing, Jiang Mengshi, Li Xiang, Shi Yingying, Zhang Junlei, Liu Yu, Shan Xinyu, Yin Hang, Guan Guannan, Du Yongzhong, Cheng Ningtao, You Jian. (2022) Dual-binding nanoparticles improve the killing effect of T cells on solid tumor. JOURNAL OF NANOBIOTECHNOLOGY, 20 (1): (1-13). [PMID:35672752] [10.1186/s12951-022-01480-z]
7. Wen Liu, Jian Dai, Wei Xue. (2018) Design and self-assembly of albumin nanoclusters as a dynamic-covalent targeting co-delivery and stimuli-responsive controlled release platform. Journal of Materials Chemistry B, 6 (42): (6817-6830). [PMID:32254698] [10.1039/C8TB01791C]

参考文献

1. Jiaqi Qiu, Siyuan Xiang, Miyao Sun, Mingqian Tan. (2023) Preparation of Polysaccharide–Protein Hydrogels with an Ultrafast Self-Healing Property as a Superior Oral Delivery System of Probiotics. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, (15): [PMID:37978937] [10.1021/acs.jafc.3c05898]
2. Hailiang Chen, Chenyu Liu, Simiao Yu, Hengjun Zhou, Farishta Shafiq, Weihong Qiao. (2023) αvβ3 Receptor-targeted acid-responsive controlled-release endosome escape doxorubicin-loaded liposomes for A549/ADR treatment. COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS, 674 (131990). [10.1016/j.colsurfa.2023.131990]
3. Pengxu Kong, Jing Dong, Wenchao Li, Zefu Li, Rui Gao, Xiang Liu, Jingrong Wang, Qi Su, Bin Wen, Wenbin Ouyang, Shouzheng Wang, Fengwen Zhang, Shuyi Feng, Donglin Zhuang, Yongquan Xie, Guangzhi Zhao, Hang Yi, Zujian Feng, Weiwei Wang, Xiangbin Pan. (2023) Extracellular Matrix/Glycopeptide Hybrid Hydrogel as an Immunomodulatory Niche for Endogenous Cardiac Repair after Myocardial Infarction. Advanced Science, (2301244). [PMID:37318159] [10.1002/advs.202301244]
4. Hailiang Chen, Chenyu Liu, Simiao Yu, Hengjun Zhou, Farishta Shafiq, Weihong Qiao. (2023) Acid/GSH Dual-Responsive Endosome Escape Dual Pro-drug Micelles Targeted Synergistic Treatment for A549/ADR. LANGMUIR, 39 (22): (7660–7671). [PMID:37219917] [10.1021/acs.langmuir.3c00439]
5. Xuedi Zhang, Xue Zhao, Zheng Hua, Shanghua Xing, Jiaxuan Li, Siyuan Fei, Mingqian Tan. (2023) ROS-triggered self-disintegrating and pH-responsive astaxanthin nanoparticles for regulating the intestinal barrier and colitis. BIOMATERIALS, 292 (121937). [PMID:36495803] [10.1016/j.biomaterials.2022.121937]
6. Luo Zhenyu, Luo Lihua, Lu Yichao, Zhu Chunqi, Qin Bing, Jiang Mengshi, Li Xiang, Shi Yingying, Zhang Junlei, Liu Yu, Shan Xinyu, Yin Hang, Guan Guannan, Du Yongzhong, Cheng Ningtao, You Jian. (2022) Dual-binding nanoparticles improve the killing effect of T cells on solid tumor. JOURNAL OF NANOBIOTECHNOLOGY, 20 (1): (1-13). [PMID:35672752] [10.1186/s12951-022-01480-z]
7. Wen Liu, Jian Dai, Wei Xue. (2018) Design and self-assembly of albumin nanoclusters as a dynamic-covalent targeting co-delivery and stimuli-responsive controlled release platform. Journal of Materials Chemistry B, 6 (42): (6817-6830). [PMID:32254698] [10.1039/C8TB01791C]

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货号 (SKU)	包装规格	是否现货
M122236-1g	1g	现货
M122236-5g	5g	现货
M122236-10g	10g	现货
M122236-25g	25g	现货

4-马来酰亚胺丁酸

库存信息

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库存信息

库存信息

基本描述

AI解读

名称和识别符

化学和物理性质

安全和危险性（GHS）

质检证书（CoA,COO,BSE/TSE 和分析图谱)

相关文档

此产品的引用文献

参考文献

溶液计算器

摩尔浓度计算器

稀释计算器

复溶计算器