MAL3-101 is a potent HSP70 allosteric inhibitor. MAL3-101 inhibits HSP70 ATPase activity by blocking Hsp40 co-chaperone interaction. MAL3-101 can be used for researching muscle invasive bladder cancer (MIBC)
In Vitro
MAL3-101 (10 μM; 24, 48, 72 hours) induces cell viability in MIBC cell lines UMUC3, T24, SW780 and J82. MCE has not independently confirmed the accuracy of these methods. They are for reference only.