MMV688845 is a nontuberculous mycobacteria (NTM) RNA polymerase inhibitor with bactericidal activity against Mycobacterium abscessus and anti-tuberculosis efficacy.
In Vitro
MMV688845 can inhibit M. abscessus ATCC 19977 in a dose-dependent manner with the MIC value of 9.3 μM. MCE has not independently confirmed the accuracy of these methods. They are for reference only.