MC-Val-Cit-PAB-Exatecan (MC-Val-Cit-PAB-DX8951) is a agent-linker conjugate for ADC. MC-Val-Cit-PAB-Exatecan is composed of a DNA topoisomerase I DX-8951 and a cathepsin cleavable ADC linker .
In Vitro
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Form:Solid
IC50& Target:Camptothecins
规格
别名
MC-Val-Cit-PAB-依沙替康
规格或纯度
Moligand™, ≥95%
英文名称
MC-Val-Cit-PAB-Exatecan
生化机理
MC-Val-Cit-PAB-Exatecan(MC-Val-Cit-PAB-DX8951)是一种用于 ADC 的药剂连接体共轭物。MC-Val-Cit-PAB-Exatecan 由 DNA 拓扑异构酶 I DX-8951 (Aladdin-E650836)和可被螯合蛋白酶裂解的 ADC 连接物组成。