计算溶液所需的质量、体积或浓度。
提供 ≥99% 纯度,适用于对基线干扰要求严格的色谱和分析工作流程。
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在色谱分析、有机合成和交叉偶联反应领域已被 0 篇同行评审文献引用。
MMG-11 quarterhydrate is a potent and selective human TLR2 antagonist with low cytotoxicity. MMG-11 quarterhydrate inhibits both TLR2/1 and TLR2/6 signaling with IC 50 s of 1.7 µM for Pam 3 CSK 4 -induced hTLR2/1 and 5.7 µM for Pam 2 CSK 4 -induced hTLR2/
Appearance:Solid
IC50& Target:TLR2
In Vitro:MMG-11 neither shows cellular toxicity nor interference with signaling induced by other TLR agonists, IL-1β or TNF. MMG-11 (0.01-100 µM) shows no cytotoxic effects up to 100 µM in peripheral blood mononuclear cells (PBMCs). MCE has not independently
Biological Activity:MMG-11 quarterhydrate is a potent and selective human TLR2 antagonist with low cytotoxicity. MMG-11 quarterhydrate inhibits both TLR2/1 and TLR2/6 signaling with IC 50 s of 1.7u202fµM for Pam 3 CSK 4 -induced hTLR2/1 and 5.7u202fµM for Pam 2 CSK 4 -induce