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MY-875 is a competitive microtubulin polymerization inhibitor with an IC 50 value of 0.92 μM. MY-875 inhibits microtubulin polymerization by targeting colchicine binding sites and activates the Hippo pathway. MY-875 induces apoptosis and has anticancer ac
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In Vitro:MY-875 (0-80 μM, 48 h) has significant anti-proliferative activity against cancer cells. MY-875 (1-10 μM) can inhibit microtubule protein polymerization with an IC 50 value of 0.92 μM while inhibiting alkylation of β-tubulin and the formation of EBI-
Biological Activity:MY-875 is a competitive microtubulin polymerization inhibitor with an IC 50 value of 0.92 μM. MY-875 inhibits microtubulin polymerization by targeting colchicine binding sites and activates the Hippo pathway. MY-875 induces apoptosis and has anticancer ac