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1、吖啶磺酰胺盐-N-乙胺基马来酰亚胺NSP-SA-N-Mal是一种具有高度特异性和反应性的生物分子标记试剂,适用于标记含巯基的蛋白、抗体或核酸等。
2、含有马来酰亚胺(Maleimide)官能团,该官能团可以与含有巯基(-SH)的生物分子通过亲和加成反应形成稳定的共价键。
3、马来酰亚胺官能团对巯基的亲和力远高于其他含有活泼氢的官能团,如氨基或羟基,因此具有较高的选择性。
1. Acridine sulfonamide salt-N-ethylamino maleimide NSP-SA-N-Mal is a highly specific and reactive biomolecular labeling reagent, suitable for labeling proteins, antibodies, or nucleic acids containing thiol groups.
2. It contains a maleimide functional group, which can form stable covalent bonds with biomolecules containing sulfhydryl (-SH) groups through an affinity addition reaction.
3. The affinity of maleimide functional groups for thiol groups is much higher than that of other functional groups containing active hydrogen, such as amino or hydroxyl groups, thus exhibiting high selectivity.