Niclosamide- 13 C 6 is the 13 C 6 labeled Niclosamide. Niclosamide (BAY2353) is an orally bioavailable chlorinated salicylanilide, with anthelmintic and potential antineoplastic activity. Niclosamide (BAY2353) inhibits STAT3 with IC50 of 0.25 μM in HeLa cells and inhibits DNA replication in a cell-free assay.
In Vitro
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs. MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Form:Solid
规格
别名
氯硝柳胺-13C6
规格或纯度
≥99%
英文名称
Niclosamide-13C6
生化机理
Niclosamide- 13 C 6 是标记为 13 C 6 的氯硝柳胺。Niclosamide (BAY2353)xa0 是一种口服生物可用的氯化水杨酰苯胺,具有驱虫和潜在的抗肿瘤活性。烟酰胺(BAY2353)对 STAT3 的抑制作用在 HeLa 细胞中的 IC50 为 0.25 μM。