NLRP3-IN-11 is a NLR family pyrin domain containing 3 (NLRP3) proteins inhibitor. NLRP3-IN-11 has biological activity for NLRP3 with an IC 50 value of <0.3 μM. NLRP3-IN-11 can be used for the researh of inflammatory and degenerative diseases including NASH, atherosclerosis and other cardiovascular diseases, Alzheimer's disease, Parkinson's disease, diabetes, gout, and numerous other autoinflammatory diseases
In Vitro
NLRP3-IN-11 has biological activity with an IC 50 value of <0.3 μM in human PBMC NLRP3 assayMCE has not independently confirmed the accuracy of these methods. They are for reference only.
Form:Solid
IC50& Target:NLRP3 <0.3 μM (IC 50 )
规格
规格或纯度
≥98%
英文名称
NLRP3-IN-11
生化机理
NLRP3-IN-11 是一种 NLR 家族含吡咯啉结构域 3(NLRP3)蛋白抑制剂。NLRP3-IN-11 对 NLRP3 具有生物活性,其 IC 50 值小于 0.3 μM。NLRP3-IN-11 可用于研究炎症性和退行性疾病,包括 NAS