NSC 694623 is a potent histone acetyltransferase (HAT) inhibitor with an IC 50 value of 15.9 μM for recombinant HAT p300/CBP-associated factor (PCAF). NSC 694623 has antiproliferative activity against certain cancer cells. NSC 694623 can be used for researching anticancer
In Vitro
NSC 694623 has antiproliferative activity against SK-N-SH with an IC 50 of 8.93 μM, and inhibits 21% of HCT116 at 25 μM. MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Form:Solid
IC50& Target:PCAF 15.9 μM (IC 50 )
规格
别名
国家安全委员会 694623
规格或纯度
≥99%
英文名称
NSC 694623
生化机理
NSC 694623 是一种强效组蛋白乙酰转移酶(HAT)抑制剂,对重组 HAT p300/CBP 相关因子(PCAF)的 IC 50 值为 15.9 μM。NSC 694623 对某些癌细胞具有抗增殖活性。NSC 694623 可用于研究和治疗癌症。