BioReagent,PBS Only 级 提供 ≥95%(SDS-PAGE) 纯度，适用于对基线干扰要求严格的色谱和分析工作流程。
🌡
储存与运输
-20°C储存,避免反复冻融。超低温运输 。请查阅批次 COA 获取详细规格。
📋
质量文档
SDS、COA、产品数据表及规格说明书均可下载。可通过批号查询获取批次 COA。
📚
文献证明
在色谱分析、有机合成和交叉偶联反应领域已被 0 篇同行评审文献引用。
概述
Serum protein found in plasma at 30 mg per 100 ml. Functions in the transport of thyroxine, vitamin A, and retinol-binding protein. Clinically, prealbumin is a sensitive indicator of impaired liver function; low levels are found in viral hepatitis, cirrhosis, malnutrition, inflammation, and surgical trauma. Prepared from plasma shown to be non reactive for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA-required tests.
BioReagent,PBS Only,≥95%(SDS-PAGE),Pre-lyophilization Protein Concentration
生化机理
Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain. Miscellaneous: Tetramer dissociation and partial unfolding leads to the formation of aggregates and amyloid fibrils. Small molecules that occupy at least one of the thyroid hormone binding sites stabilize the tetramer, and thereby stabilize the native state and protect against misfolding and the formation of amyloid fibrils. Two binding sites for thyroxine are located in the channel. Less than 1% of plasma prealbumin molecules are normally involved in thyroxine transport. L-thyroxine binds to the transthyretin by an order of magnitude stronger than does the triiodo-L-thyronine. Thyroxine-binding globulin is the major carrier protein for thyroid hormones in man. About 40% of plasma transthyretin circulates in a tight protein-protein complex with the plasma retinol-binding protein (RBP). The formation of the complex with RBP stabilizes the binding of retinol to RBP and decreases the glomerular filtration and renal catabolism of the relatively small RBP molecule. There is evidence for 2 binding sites for RBP, one possibly being a region that includes Ile-104, located on the outer surface of the transthyretin molecule.
种属
人(Human)
来源
天然
预测分子量
55 kDa
CAS编号和信息
87090-18-4
分子类型
蛋白质
产品线
生物产品
储存与运输
物理形态
冻干(Lyophilized)
储存缓冲液
Lyophilized from 50 mM Na phosphate, 150 mM NaCl, pH 7.5.
浓度
Pre-lyophilization Protein Concentration
复溶
After centrifugation, we suggest addition of de-ionized H2O to the original volume (See COA), followed by gentle mixingto ensure adequate homogenization. If further dilution is required, please use the lyophilization buffer.
ZJ25F0825189
危险品化学品经营许可证（带存储）