Apolipoprotein CI is one of the protein components of VLDL lipoprotein. The normal plasma concentration of Apo CI is 4-7 mg per 100 ml. Elevated levels of Apo CI may offer some protection from obesity and insulin-dependent diabetes. Some evidence exists that the Apo CI H2 gene is positively associated with late-onset Alzheimer's disease.
Prepared from fresh, non-frozen plasma shown to be non reactive for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests.
Inhibitor of lipoprotein binding to the low density lipoprotein (LDL) receptor, LDL receptor-related protein, and very low density lipoprotein (VLDL) receptor. Associates with high density lipoproteins (HDL) and the triacylglycerol-rich lipoproteins in the plasma and makes up about 10% of the protein of the VLDL and 2% of that of HDL. Appears to interfere directly with fatty acid uptake and is also the major plasma inhibitor of cholesteryl ester transfer protein (CETP). Binds free fatty acids and reduces their intracellular esterification. Modulates the interaction of APOE with beta-migrating VLDL and inhibits binding of beta-VLDL to the LDL receptor-related protein.
种属
人(Human)
来源
天然
预测分子量
6.6 kDa
CAS编号和信息
2235444-72-9
分子类型
蛋白质
产品线
生物产品
储存与运输
物理形态
冻干(Lyophilized)
储存缓冲液
Lyophilized from 10 mM NH4HCO3, pH 7.4
浓度
冻干前浓度：见COA
复溶
After centrifugation, we suggest re-addition of lyophilization buffer (10 mM NH4HCO3, pH 7.4) to the original volume (See COA), followed by gentle mixingto ensure adequate homogenization. If further dilution is required, please use the lyophilization buffer.
ZJ26F0333376
危险品化学品经营许可证（带存储）