| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| np001156-25μg |
25μg |
期货  |
| |
| np001156-100μg |
100μg |
期货 |
|
| 产品名称 | 血管紧张素原,人血浆 |
|---|---|
| 别名 | Hypertensinogen, Renin substrate |
| 规格或纯度 | ≥95%(SDS-PAGE), Extinction Coefficient: 0.92 |
| 产品介绍 |
Buy Purified Native Angiotensinogen from Human Plasma direct from the manufacturer. Angiotensinogen (AGT) is a glycoprotein found in plasma at a concentration of 2.8-7.1 mg per 100mL in healthy individuals. AGT is produced primarily by the liver but also is synthesized in the brain, large arteries, kidneys and adipose tissue. In plasma it exists as a monomeric form (55-65 kDa) as well as a high molecular mass form (200-550 kDa). In non-pregnant individuals with normal blood pressure, the high molecular mass form accounts for 3% of total circulating AGT. In the first half of pregnancy the total AGT increases by 4-fold and the high molecular mass form increases by 20-fold. Up to 80% of the total AGT in amniotic fluid is the high molecular mass form. Angiotensinogen is an essential component of the renin-angiotensin system, a potent regulator of blood pressure, body fluid and electrolyte homeostasis. It functions as the substrate for human renin and is the precursor molecule for Angiotensins 1,2,3,4, 1-9, 1-7, 1-5 and 1-4. AGT is also a member of the SERPIN family but it is not known to possess protease-inhibitory activity. Levels in plasma are increased by plasma corticosteroid, estrogen, thyroid hormone and angiotensin-2 levels. Synonym: Hypertensinogen, Renin substrate Prepared from plasma shown to be non-reactive for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA-required tests. |
| 预测分子量 | 55,000-65,000Da |
| 物理形态 | 冻干(Lyophilized) |
|---|---|
| 储存缓冲液 | Lyophilized from 30 mM sodium phosphate, pH 6.8 |
| 浓度 | Extinction Coefficient: 0.92 |
| 储存温度 | -20°C储存 |
| 运输条件 | 超低温冰袋运输 |
| 分子类型 | 蛋白质 |
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