Found in human serum at 60 mg per 100 ml. This protein is a negative acute-phase reactant. Clinically, concentrations are reduced in cancer patients. AHSG levels are positively correlated with gestational diabetes and negatively correlated with neonatal skeletal development. Studies show AHSG to be present at high concentrations in the peritoneal fluids of patients with endometriosis. Extinction Coefficient: 0.54 Prepared from plasma shown to be non reactive for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests.
BioReagent, 天然, ≥90%(SDS-PAGE), Pre-lyophilization Protein Concentration
生化机理
Promotes endocytosis, possesses opsonic properties and influences the mineral phase of bone. Shows affinity for calcium and barium ions.
Post-translational: Phosphorylated by FAM20C in the extracellular medium. O- and N-glycosylated. O-glycosylated with core 1 or possibly core 8 glycans. N-glycan at Asn-156: Hex5HexNAc4; N-glycan heterogeneity at Asn-176: Hex5HexNAc4 (major) and Hex6HexNAc5 (minor).
种属
人(Human)
来源
天然
预测分子量
49 kDa
分子类型
蛋白质
产品线
生物产品
储存与运输
物理形态
冻干(Lyophilized)
储存缓冲液
Lyophilized from 20 mM Tris-HCl, 200 mM NaCl, pH 8.0.
浓度
Pre-lyophilization Protein Concentration
复溶
After centrifugation, we suggest addition of de-ionized H2O to the original volume (See COA), followed by gentle mixingto ensure adequate homogenization. If further dilution is required, please use the lyophilization buffer.
储存条件
-20°C储存,避免反复冻融
运输条件
超低温运输
稳定性与储存
长期储存-20℃(5年);复溶后建议分装,避免反复冻融。
图片
α2-hs-Glycoprotein from Human Plasma (np001159) - SDS-PAGE
2 μg/lane of α2-hs-Glycoprotein from Human Plasma was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 51 kDa.