计算溶液所需的质量、体积或浓度。
为什么选择此级别
提供 ≥99% 纯度，适用于对基线干扰要求严格的色谱和分析工作流程。
储存与运输
避光,干燥,-80℃储存。特低温运输 。请查阅批次 COA 获取详细规格。
质量文档
SDS、COA、产品数据表及规格说明书均可下载。可通过批号查询获取批次 COA。
文献证明
在色谱分析、有机合成和交叉偶联反应领域已被 0 篇同行评审文献引用。
概述
(Thr4,Gly7)-Oxytocin, an Oxytocin analogue, is a specific OT receptor agonist. (Thr4,Gly7)-Oxytocin also excites subicular neurons via activation of TRPV1 channels, and depression of K + channels.
In Vitro
(Thr4,Gly7)-Oxytocin (1 μM, 1 min) evokes an inward current of 5.9 pA in paraventricular thalamus (PVT) neurons. (Thr4,Gly7)-Oxytocin (1 μM, 1 min) increases spontaneous excitatory postsynaptic currents (sEPSCs) frequency in PVT neurons. (Thr4,Gly7)-Oxytocin (0.3 μM, 5 min) induces depolarization in both bursting cells and regular firing cells. (Thr4,Gly7)-Oxytocin (0.3 μM, 5 min) depolarizes subicular neurons by activating TRPV1 channels. MCE has not independently confirmed the accuracy of these methods. They are for reference only.
In Vivo
(Thr4,Gly7)-Oxytocin (1 μM, direct intra-PVT infusion for 1 min) evokes depolarization on TGOT-responsive neurons in mice . (Thr4,Gly7)-Oxytocin (100 ng, intracerebroventrical injection) increases nitric oxide production in the paraventricular nucleus of the hypothalamus of male rats. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: Swiss Webster mice Dosage: 1 μM Administration: Intratracheal administration for 24 h Result: Excited 34.3% of aPVT neurons, 57.6% of mPVT neurons, and 60.0% of pPVT neurons. Increased the firing rate of TGOT-responsive PVT neurons in all subregions.
Form:Solid
IC50& Target:OT receptors, K + channels
规格
别名
(Thr4,Gly7)-催产素
规格或纯度
≥99%
英文名称
(Thr4,Gly7)-Oxytocin
生化机理
(Thr4,Gly7)-催产素是一种催产素类似物，是一种特异性催产素受体激动剂。(Thr4,Gly7)-催产素还能通过激活 TRPV1 通道和抑制 K + 通道来兴奋泡状神经元。
储存条件
避光,干燥,-80℃储存
运输条件
特低温运输
作用类型
激动剂
纯度
≥99%
名称和识别符
分子类型
肽
分子量
940.10
技术文档
高级数据
化学和物理性质
溶解性
H2O : 100 mg/mL (106.37 mM; Need ultrasonic)
质检证书（CoA,COO,BSE/TSE 和分析图谱)
C of A & Other Certificates(BSE/TSE, COO):
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溶液计算器
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