Orexin B, human (TFA) is an endogenous agonist at Orexin receptor with K i s of 420 and 36 nM for OX1 and OX2, respectively.
Appearance:Solid
IC50& Target:Ki: 420 nM (OX1), 36 nM (OX2) .
In Vitro:Orexin B is derived by proteolytic amino acid precursor, prepro-orexin, which is encoded by a gene localized to chromosome 17q21 in humans. In radioligand binding studies, Orexin B has a higher affinity for the OX2 receptor. Human Orexin B has two am
In Vivo:Human Orexin B significantly augments food intake; at the 2 hr time point, 5- and 12-fold stimulation of food consumption is observed by 3 nM and 30 nM orexin-B, respectively. MCE has not independently confirmed the accuracy of these methods. They ar
Biological Activity:Orexin B, human (TFA) is an endogenous agonist at Orexin receptor with K i s of 420 and 36 nM for OX1 and OX2, respectively.
H2O Peptide Solubility and Storage Guidelines: 1.Calculate the length of the peptide. 2.Calculate the overall charge of the entire peptide according to the following table: Contents Assign value Acidic amino acid Asp (D), Glu (E), a